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Do autoantibodies shape cancer immunosurveillance?
Necker Hosp Sick Children, Necker Branch, Lab Human Genet Infect Dis, INSERM,U1163, Paris, France.;Paris Cite Univ, Imagine Inst, Paris, France.;Necker Hosp Sick Children, Pediat Hematol Immunol & Rheumatol Unit, AP HP, Paris, France..
CDI Labs, Baltimore, MD USA..
Univ Oxford, Canc Epidemiol Unit, Oxford Populat Hlth, Oxford OX3 7LF, England..
Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology, Genetics and Genomics.ORCID iD: 0000-0002-6163-9540
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2026 (English)In: Cell, ISSN 0092-8674, E-ISSN 1097-4172, Vol. 189, no 15, p. 4525-4530Article in journal, Editorial material (Other academic) Published
Abstract [en]

Why cancer arises, progresses, or proves fatal in some people but not others remains largely unresolved. Antibody repertoires, including autoantibodies targeting immune pathways, may shape cancer immunosurveillance. Mapping antibody landscapes across cancer-free, at-risk, and cancer-affected individuals could clarify their roles in cancer susceptibility and disease outcome.
Place, publisher, year, edition, pages
Cell Press, 2026. Vol. 189, no 15, p. 4525-4530
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Cancer and Oncology Immunology in the Medical Area
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URN: urn:nbn:se:uu:diva-595653DOI: 10.1016/j.cell.2026.06.021ISI: 001834928300001PubMedID: 42492493Scopus ID: 2-s2.0-105045033136OAI: oai:DiVA.org:uu-595653DiVA, id: diva2:2093694
Available from: 2026-08-19 Created: 2026-08-19 Last updated: 2026-08-19Bibliographically approved

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