One of the most transformative developments today is the integration of generative artificial intelligence into the development of critical software-intensive cyber-physical systems. From autonomous vehicles to industrial robotics, these systems are entering a new era shaped by artificial intelligence-driven development and automation. In this paper, we consider software engineering, artificial intelligence, artificial intelligence ethics, and social aspects, to explore how such technologies can be harnessed safely, transparently, and with human values at the center. Our contributions include a vision for software engineering, guiding the engineering of future trustworthy safety-critical cyber-physical systems under the influence of generative artificial intelligence. We critically analyze how three established certification principles can be leveraged to cope with the societal and technical tensions introduced by generative artificial intelligence adoption, and propose a research and practice agenda to ensure that future cyber-physical systems development and operations cycle remain trustworthy, both from a system (hardware and software) and from a societal perspective.