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Effects of OsteoStrong vs. dynamic multicomponent exercise on physical function in older women in the BONEMORE randomized controlled trial.
Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, 171 77, Sweden. .
Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, 171 77, Sweden. Academic Healthcare Centre Stockholm, Stockholm, Sweden..
Swedish School of Sport and Health Sciences, GIH, Department of Physical Activity and Health. Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden..ORCID iD: 0000-0001-9040-2158
Department of Health, Medicine and Caring Science, Linköping University, Linköping, Sweden..
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2026 (English)In: Aging Clinical and Experimental Research, ISSN 1594-0667, E-ISSN 1720-8319, Vol. 38, article id 168Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Limited research exists on the effects of OsteoStrong on physical function in older women.

AIM: This randomized controlled trial aimed to evaluate and compare the effects of OsteoStrong (OS) and dynamic multicomponent exercise (DME) on functional outcomes in older women with osteopenia or osteoporosis.

METHODS: A total of 194 women aged 65-79 years with a T-score of ≤-1.0 at the hip and/or spine were randomized to nine months of either OS (once weekly, 20 min) or DME (twice weekly, 60 min). Outcomes included measures of muscle strength (hand grip and back strength), back and trunk endurance, mobility (sit-to-stand tests, gait speed, Timed Up and Go), and balance (one-leg standing time, tandem standing, tandem walking). Measurements were conducted at baseline and again at nine months.

RESULTS: Both OS and DME showed significant improvements in grip strength, back strength, isometric trunk flexion endurance, gait speed 30 m (m/sec), 5 sit-to-stand (sec) and 50 sit-to-stand speed (n/sec) with no significant between-group differences. DME resulted in greater improvements in gait speed 30 m (+ 7.1% vs. +3.2%, p = 0.001), isometric trunk extension (+ 27.6% vs. +4.4%, p = 0.007), and one-leg standing balance (right leg: +13.1% vs. -2.1%, p = 0.001; left leg: +13.3% vs. -2.4%, p = 0.001) compared to OS.

CONCLUSION: These findings suggest that while both OS and DME improve physical function in older women with osteopenia or osteoporosis, DME provides superior benefits in gait speed, back muscle endurance, and balance. These findings should be interpreted with caution, as they are based on secondary outcomes.

Place, publisher, year, edition, pages
Springer, 2026. Vol. 38, article id 168
Keywords [en]
Balance, Dynamic exercise, Isometric exercise, Muscle strength, Osteopenia, Osteoporosis, Physical function, Postmenopausal women
National Category
Physiotherapy
Research subject
Medicine/Technology
Identifiers
URN: urn:nbn:se:gih:diva-9343DOI: 10.1007/s40520-026-03421-4PubMedID: 42402085OAI: oai:DiVA.org:gih-9343DiVA, id: diva2:2087653
Note

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

Available from: 2026-07-22 Created: 2026-07-22 Last updated: 2026-08-27

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