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Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot Trial
Örebro Univ, Fac Med & Hlth, Sch Med Sci, Sodra Grey Rosengatan 32, S-70362 Örebro, Sweden..ORCID iD: 0000-0002-7151-3642
Örebro Univ, Fac Med & Hlth, Sch Med Sci, Sodra Grey Rosengatan 32, S-70362 Örebro, Sweden.;Örebro Univ, Sch Hospitality Culinary Arts & Meal Sci, S-71202 Grythyttan, Sweden..
Örebro Univ, Fac Med & Hlth, Sch Med Sci, Sodra Grey Rosengatan 32, S-70362 Örebro, Sweden.;Örebro Univ, Sch Hospitality Culinary Arts & Meal Sci, S-71202 Grythyttan, Sweden..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism.ORCID iD: 0000-0002-8620-4586
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2021 (English)In: Nutrients, E-ISSN 2072-6643, Vol. 13, no 3, article id 902Article in journal (Refereed) Published
Abstract [en]

Healthy diet interventions have been shown to improve depressive symptoms, but there is a need for randomized controlled trials (RCTs) that are double blind and investigate biological mechanisms. The primary objectives of this randomized controlled pilot trial were to test the palatability of the meals and the acceptability of the intervention in preparation for an 8-week RCT in the future, which will investigate whether a healthy Nordic diet improves depressive symptoms in individuals with major depressive disorder, and associated biological mechanisms. Depressed (n = 10) and non-depressed (n = 6) women and men were randomized to receive either a healthy Nordic diet (ND) or a control diet (CD) for 8 days. Participants were blinded to their diet allocation and the study hypotheses. Health questionnaires were completed before and after the intervention and, throughout the study, questionnaires assessed participants' liking for the meals, their sensory properties, adherence, and open-ended feedback. In the ND group, 75% of participants consumed only the provided foods, as instructed, compared to 50% of CD participants. The meals of both diets, on average, received good ratings for liking and sensory properties, though the ND ratings were somewhat higher. Overall, results were positive and informative, indicating that the planned RCT will be feasible and well-accepted, with some proposed modifications.

Place, publisher, year, edition, pages
MDPI MDPI, 2021. Vol. 13, no 3, article id 902
Keywords [en]
depression, major depressive disorder, diet, nutrition, randomized controlled trial, randomized controlled pilot trial, healthy Nordic diet, mental health, palatability, food liking
National Category
Nutrition and Dietetics
Identifiers
URN: urn:nbn:se:uu:diva-442113DOI: 10.3390/nu13030902ISI: 000633936000001PubMedID: 33802181OAI: oai:DiVA.org:uu-442113DiVA, id: diva2:1553625
Available from: 2021-05-10 Created: 2021-05-10 Last updated: 2024-01-15Bibliographically approved

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