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  • 51.
    Bergström, Anna
    et al.
    Stockholms universitet, Humanistiska fakulteten, Institutionen för språkdidaktik.
    Ljungros, Kristina
    Forsberg Nilsson, Karin
    Ericson, Emilia
    Lindenfors, Patrik
    Stockholms universitet, Naturvetenskapliga fakulteten, Zoologiska institutionen, Avdelningen för zoologisk ekologi. Stockholms universitet, Humanistiska fakulteten, Centrum för evolutionär kulturforskning.
    Larhammar, Dan
    Nu hotas kvinnors rätt till sina kroppar2014Inngår i: Aftonbladet, ISSN 0349-1145Artikkel i tidsskrift (Annet (populærvitenskap, debatt, mm))
  • 52.
    Bergström, Ulrika
    et al.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Teknisk-naturvetenskapliga fakulteten, Biologiska sektionen, Institutionen för fysiologi och utvecklingsbiologi. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Teknisk-naturvetenskapliga fakulteten, Biologiska sektionen, Institutionen för fysiologi och utvecklingsbiologi. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Teknisk-naturvetenskapliga fakulteten, Biologiska sektionen, Institutionen för fysiologi och utvecklingsbiologi, Ekotoxikologi. ekotoxikologi.
    Olsson, Jan
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Teknisk-naturvetenskapliga fakulteten, Biologiska sektionen, Institutionen för fysiologi och utvecklingsbiologi. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Teknisk-naturvetenskapliga fakulteten, Biologiska sektionen, Institutionen för fysiologi och utvecklingsbiologi. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Teknisk-naturvetenskapliga fakulteten, Biologiska sektionen, Institutionen för fysiologi och utvecklingsbiologi, Ekotoxikologi. ekotoxikologi.
    Hvidsten, Torgeir R
    Komorowski, Jan
    Brandt, Ingvar
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Teknisk-naturvetenskapliga fakulteten, Biologiska sektionen, Institutionen för fysiologi och utvecklingsbiologi. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Teknisk-naturvetenskapliga fakulteten, Biologiska sektionen, Institutionen för fysiologi och utvecklingsbiologi. Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Teknisk-naturvetenskapliga fakulteten, Biologiska sektionen, Institutionen för fysiologi och utvecklingsbiologi, Ekotoxikologi. ekotoxikologi.
    Neurotoxicity of the Olfactory toxicant 2,6-Dichlorophenyl Methylsulphone in Olfactory bulb:Impaired expression of genes relating to neurodegenerative disease2007Inngår i: DIOXIN2007, 2007, s. 1841-1844Konferansepaper (Fagfellevurdert)
  • 53. Berntsson, Jonna
    et al.
    Lundgren, Sebastian
    Nodin, Björn
    Uhlén, Mathias
    KTH, Skolan för bioteknologi (BIO), Proteomik och nanobioteknologi. KTH, Centra, Science for Life Laboratory, SciLifeLab.
    Gaber, Alexander
    Jirström, Karin
    Expression and prognostic significance of the polymeric immunoglobulin receptor in epithelial ovarian cancer2014Inngår i: Journal of Ovarian Research, ISSN 1757-2215, E-ISSN 1757-2215, Vol. 7, nr 1, s. 26-Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background: High expression of the polymeric immunoglobulin receptor (PIGR) has previously been associated with a favourable prognosis in a few cancer forms, but its expression and relationship with clinical outcome in epithelial ovarian cancer (EOC) has not yet been reported. The aim of this study was therefore to examine the clinicopathological correlates and prognostic significance of PIGR expression in EOC. Methods: After an initial screening in the Human Protein Atlas portal, a validated antibody was selected for extended analysis of immunohistochemical PIGR expression in tissue microarrays with tumours from 154 incident cases of EOC from two pooled prospective population-based cohorts. Subsets of corresponding benign-appearing fallopian tubes (n = 38) and omental metastases (n = 33) were also analysed. Kaplan-Meier analysis and Cox regression analysis were applied to examine the impact of PIGR expression on overall survival (OS) and ovarian cancer-specific survival (OCSS). Results: PIGR expression was significantly higher in fallopian tubes compared to primary tumours and metastases (p < 0.001) and lower in carcinoma of the serous subtype compared to other carcinomas (p < 0.001). PIGR expression was significantly associated with lower grade (p = 0.001), mucinous histological subtype (p = 0.002), positive progesterone receptor expression (p = 0.009) and negative or low Ki-67 expression (p = 0.003). Kaplan-Meier analysis revealed a significantly improved OS (p = 0.013) and OCSS (p = 0.009) for patients with tumours displaying high expression of PIGR. These associations were confirmed in unadjusted Cox regression analysis (HR = 0.48; 95% CI 0.26-0.87; p = 0.015 for OS and HR = 0.43, 95% CI 0.22-0.82; p = 0.011 for OCSS) but did not remain significant after adjustment for age, grade and clinical stage. Conclusions: This study provides a first demonstration of PIGR expression in human fallopian tubes, primary EOC tumours and metastases. High tumour-specific expression of PIGR was found to be associated with a favourable prognosis in unadjusted, but not in adjusted, analysis. These findings are novel and merit further investigation.

  • 54.
    Bisang, Irene
    et al.
    Naturhistoriska riksmuseet, Enheten för botanik.
    Hedenäs, Lars
    Naturhistoriska riksmuseet, Enheten för botanik.
    Drepanocladus turgescens (T. Jensen) Broth. doch im Engadin2017Inngår i: Meylania, ISSN 1018-8142, Vol. 59, s. 9-13Artikkel i tidsskrift (Annet (populærvitenskap, debatt, mm))
  • 55.
    Bjarre, Jonas
    KTH, Skolan för bioteknologi (BIO).
    Luftning i fedbatchodlingar av Saccharomyces cerevisiae2016Independent thesis Advanced level (degree of Master (Two Years)), 20 poäng / 30 hpOppgave
  • 56. Björn, Lars Olof
    et al.
    Bengtson, Sven-Axel
    Shaoshan, Li
    Hecker, Christoph
    Ullah, Saleem
    Roos, Arne
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Tekniska sektionen, Institutionen för teknikvetenskaper, Fasta tillståndets fysik.
    Nilsson, Annica M.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Tekniska sektionen, Institutionen för teknikvetenskaper, Fasta tillståndets fysik.
    Thermal emissivity of avian eggshells2016Inngår i: Journal of Thermal Biology, ISSN 0306-4565, E-ISSN 1879-0992, Vol. 57, s. 1-5Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The hypothesis has been tested that evolution has resulted in lower thermal emissivity of eggs of birds breeding openly in cold climates than of eggs of birds that nest under protective covering or in warmer climates. Directional thermal emissivity has been estimated from directional-hemispherical reflectance spectra. Due to several methodological difficulties the absolute emissivity is not accurately determined, but differences between species are obvious. Most notably, small waders of the genus Calidris, breeding in cold climates on the tundra, and in most cases with uniparental nest attendance, have low directional emissivity of their eggshells, about 0.92 when integration is carried out for wavelengths up to 16 mu m. Species belonging to Galloanserinae have the highest directional emissivity, about 0.96, of their eggs. No differences due to climate or breeding conditions were found within this group. Eggs of most other birds tested possess intermediate emissivity, but the values for Pica pica and Corvus corone cornix are as low as for Calidris. Large species-dependent differences in spectral reflectance were found at specific wavelengths. For instance, at 4.259 mu m the directional-hemispherical reflectance for galliforms range from 0.05 to 0.09, while for Fratercula arctica and Fulmarus glacialis it is about 0.3. The reflection peaks at 6.5 and 11.3 mu m due to calcite are differentially attenuated in different species. In conclusion, the hypothesis that evolution has resulted in lower thermal emissivity of bird eggs being exposed in cold climates is not supported by our results. The emissivity is not clearly related to nesting habits or climate, and it is unlikely that the small differences observed are ecologically important. The spectral differences between eggs that nevertheless exist should be taken into account when using infrared thermometers for estimating the surface temperature of avian eggs.

  • 57.
    Boalt, Elin
    Södertörns högskola, Institutionen för livsvetenskaper.
    Ecology and evolution of tolerance in two cruciferous species2008Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    Tolerance to herbivory is the ability of plants to maintain fitness in spite of damage. The goal of this thesis is to investigate the genetic variation and expression of tolerance within species, determine whether and in what conditions tolerance has negative side-effects, and how tolerance is affected by different ecological factors. Tolerance is investigated with special focus on the effects of different damage types, competitive regimes, history of herbivory, and polyploidization in plants. Studies are conducted as a literature review and three experiments on two cruciferous species Raphanus raphanistrum and Cardamine pratensis.

    In the tolerance experiments, plants are subjected to artificial damage solely, or in a combination with natural damage. A literature review was conducted in order to investigate the effects of damage method. We found that traits related to tolerance, such as growth and fitness were not as sensitive in regard to damage method as measures of induced chemical traits, or measures of secondary herbivory.

    Genetic variation of tolerance was demonstrated within populations of R. raphanistrum and between subspecies of C. pratensis. In R. raphanistrum, traits involved in floral display and male fitness were positively associated with plant tolerance to herbivore damage. A potential cost of tolerance was demonstrated as a negative correlation between levels of tolerance in high and low competitive regimes. I found no evidence of other proposed costs of tolerance in terms of highly tolerant plants suffering of reduced fitness in the absence of herbivores or trade-offs in terms of a negative association between tolerance to apical and leaf damage, or between tolerance and competitive ability. In C. pratensis, higher ploidy level in plants involved higher levels of tolerance measured as clonal reproduction. Furthermore, populations exposed to higher levels of herbivory had better tolerance than populations exposed to lower levels of herbivory. In this thesis, I demonstrate evidence of different components for the evolution of tolerance in plants: genotypic variation, selective factors in terms of costs and ploidization, and selective agents in terms of changing environment or herbivore pressure.

  • 58.
    Boalt, Elin
    Stockholms universitet, Naturvetenskapliga fakulteten, Botaniska institutionen.
    Ecology and evolution of tolerance in two cruciferous species2008Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    Tolerance to herbivory is the ability of plants to maintain fitness in spite of damage. The goal of this thesis is to investigate the genetic variation and expression of tolerance within species, determine whether and in what conditions tolerance has negative side-effects, and how tolerance is affected by different ecological factors. Tolerance is investigated with special focus on the effects of different damage types, competitive regimes, history of herbivory, and polyploidization in plants. Studies are conducted as a literature review and three experiments on two cruciferous species Raphanus raphanistrum and Cardamine pratensis.

    In the tolerance experiments, plants are subjected to artificial damage solely, or in a combination with natural damage. A literature review was conducted in order to investigate the effects of damage method. We found that traits related to tolerance, such as growth and fitness were not as sensitive in regard to damage method as measures of induced chemical traits, or measures of secondary herbivory.

    Genetic variation of tolerance was demonstrated within populations of R. raphanistrum and between subspecies of C. pratensis. In R. raphanistrum, traits involved in floral display and male fitness were positively associated with plant tolerance to herbivore damage. A potential cost of tolerance was demonstrated as a negative correlation between levels of tolerance in high and low competitive regimes. I found no evidence of other proposed costs of tolerance in terms of highly tolerant plants suffering of reduced fitness in the absence of herbivores or trade-offs in terms of a negative association between tolerance to apical and leaf damage, or between tolerance and competitive ability. In C. pratensis, higher ploidy level in plants involved higher levels of tolerance measured as clonal reproduction. Furthermore, populations exposed to higher levels of herbivory had better tolerance than populations exposed to lower levels of herbivory. In this thesis, I demonstrate evidence of different components for the evolution of tolerance in plants: genotypic variation, selective factors in terms of costs and ploidization, and selective agents in terms of changing environment or herbivore pressure.

  • 59.
    Bodin, Hristina
    et al.
    Högskolan Kristianstad, Sektionen för lärande och miljö, Avdelningen för Naturvetenskap. Högskolan Kristianstad, Forskningsmiljön Man & Biosphere Health (MABH). SLU, Alnarp.
    Asp, Håkan
    SLU, Alnarp.
    Hultberg, Malin
    SLU, Alnarp.
    Effects of biopellets composed of microalgae and fungi on cadmium present at environmentally relevant levels in water2017Inngår i: International journal of phytoremediation, ISSN 1522-6514, E-ISSN 1549-7879, Vol. 19, nr 5, s. 500-504Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Removal of cadmium (Cd) present at low levels (1 µg L−1) in water was investigated using three different microorganism treatments: the microalga Chlorella vulgaris, the fungus Aspergillus niger and for the first time biopellets composed of C. vulgaris and A. niger. After 5 days, all microorganism treatments resulted in significantly lower Cd concentrations compared with the control. Biopellets treatment resulted in significantly lower pH values than other microorganism treatments, indicating that the biopellets should be investigated further for their water treatment capacity, since pH is a factor affecting the fate of numerous pollutants in water. Use of biopellets as a method to simplify harvesting of microalgae from water is also suggested.

  • 60.
    Bohlin, Emma
    Högskolan i Gävle, Akademin för teknik och miljö, Avdelningen för elektronik, matematik och naturvetenskap.
    Trädgårdens betydelse för medlemmar i bostadsrättsföreningar: –ur ett hälsomässigt, estetiskt och skötselmässigt perspektiv2012Independent thesis Basic level (university diploma), 10 poäng / 15 hpOppgave
    Abstract [sv]

    Syftet med studien handlar om att försöka förstå vilken betydelse trädgårdsmiljön har för människor som bor i bostadsrättslägenheter - ur ett hälsomässigt, estetiskt och skötselmässigt perspektiv. Framför allt handlar studien om att ta reda på hur medlemmarna använder sin trädgård och om den har någon hälsomässig betydelse. Studien ska undersöka hur de ser på utformningen av trädgårdsmiljön i sitt bostadsområde, samt hur de skulle föredra att ha den. Den ska också undersöka vilken syn medlemmarna har på skötselfrågan och hur föreningen valt att lösa skötseln av trädgården. Studien bygger på fem kvalitativa intervjuer med representanter från bostadsrättsföreningar som fått besvara frågor om medlemmarnas syn på sina trädgårdsmiljöer.

  • 61.
    Bohlin, Matilda
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för biologisk grundutbildning.
    DEHP - från mjukgörare till hormonstörande2014Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 62. Bondesson, Maria
    et al.
    Jönsson, Jill
    Pongratz, Ingemar
    Olea, Nicholas
    Cravedi, Jean-Pierre
    Zalko, Daniel
    Håkansson, Helen
    Halldin, Krister
    Institutet för miljömedicin, Karolinska Institutet.
    Di Lorenzo, Diego
    Behl, Christian
    Manthey, Dieter
    Balaguer, Patrick
    Demeneix, Barbara
    Fini, Jean Baptiste
    Laudet, Vincent
    Gustafsson, Jan-Ake
    A CASCADE of effects of bisphenol A.2009Inngår i: Reproductive Toxicology, ISSN 0890-6238, E-ISSN 1873-1708, Vol. 28, nr 4, s. 563-7Artikkel i tidsskrift (Fagfellevurdert)
  • 63.
    Borg, Carola
    et al.
    Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Institutionen för miljö- och livsvetenskaper.
    Gericke, Niklas
    Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Institutionen för miljö- och livsvetenskaper.
    Höglund, Hans-Olof
    Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Institutionen för miljö- och livsvetenskaper.
    Bergman, Eva
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi. Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), Institutionen för miljö- och livsvetenskaper.
    Subject- and experience-bound differences in teachers' conceptual understanding of sustainable development2014Inngår i: Environmental Education Research, ISSN 1350-4622, E-ISSN 1469-5871, Vol. 20, nr 4, s. 526-551Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    This article describe the results of a nationwide questionnaire study of 3229 Swedish upper secondary school teachers’ understanding of sustainable development in relation to their subject discipline and teaching experience. Previous research has shown that teachers have difficulties understanding the complex concept of sustainable development. According to the Swedish curriculum all teachers in all subjects should integrate a holistic perspective of sustainable development including economic, ecological and social dimensions. This study shows that teachers differ in their understanding of the concept mostly according to their subject traditions. Social science teachers emphasize social dimensions, and science teachers’ ecological dimensions, respectively. Teachers are aware of the relevance of the three dimensions to various degrees, but do not generally have a holistic understanding. The greatest uncertainty in teachers’ understanding is related to the economic dimension. Science and social science teachers are critical of incorporating economic growth into the concept of sustainable development while language, vocational and esthetical-practical teachers are not. No experience-bound differences of the teachers’ understanding could be found, but recently qualified teachers consider their understanding of sustainable development to be poorer in comparison to more experienced teachers’ self-evaluation. The study highlights the need for further training in sustainable development since more than 70 % of the questioned teachers stated that they need such training.

  • 64.
    Bottinelli, Arianna
    et al.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Matematiska institutionen, Tillämpad matematik och statistik.
    van Wilgenburg, E.
    Fordham Univ, Dept Biol Sci, Bronx, NY 10458 USA..
    Sumpter, David J. T.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Matematiska institutionen, Tillämpad matematik och statistik.
    Latty, T.
    Univ Sydney, Sch Biol Sci, Sydney, NSW 2006, Australia..
    Local cost minimization in ant transport networks: from small-scale data to large-scale trade-offs2015Inngår i: Journal of the Royal Society Interface, ISSN 1742-5689, E-ISSN 1742-5662, Vol. 12, nr 112, artikkel-id 20150780Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Transport networks distribute resources and information in many human and biological systems. Their construction requires optimization and balance of conflicting criteria such as robustness against disruptions, transport efficiency and building cost. The colonies of the polydomous Australian meat ant Iridomyrmex purpureus are a striking example of such a decentralized network, consisting of trails that connect spatially separated nests. Here we study the rules that underlie network construction in these ants. We find that a simple model of network growth, which we call the minimum linking model (MLM), is sufficient to explain the growth of real ant colonies. For larger networks, the MLM shows a qualitative similarity with a Euclidean minimum spanning tree, prioritizing cost and efficiency over robustness. We introduce a variant of our model to show that a balance between cost, efficiency and robustness can be also reproduced at larger scales than ant colonies. Remarkably, such a balance is influenced by a parameter reflecting the specific features of the modelled transport system. The extended MLM could thus be a suitable source of inspiration for the construction of cheap and efficient transport networks with non-zero robustness, suggesting possible applications in the design of human-made networks.

  • 65.
    Britton, Tom
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Matematiska institutionen.
    Lindenstrand, David
    Stockholms universitet, Naturvetenskapliga fakulteten, Matematiska institutionen.
    Inhomogeneous epidemics on weighted networks2012Inngår i: Mathematical Biosciences, ISSN 0025-5564, E-ISSN 1879-3134, Vol. 240, nr 2, s. 124-131Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g., reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such that individuals are heterogeneous in terms of how susceptible and infectious they are. The basic reproduction number R-0 is derived and studied for various examples, but also the size and probability of a major outbreak. The qualitative conclusion is that R-0 gets larger as the community becomes more heterogeneous but that different heterogeneities (degree distribution, weight, susceptibility and infectivity) can sometimes have the cumulative effect of homogenizing the community, thus making R-0 smaller. The effect on the probability and final size of an outbreak is more complicated.

  • 66.
    Buckland, Philip I.
    Umeå universitet, Humanistiska fakulteten, Institutionen för idé- och samhällsstudier, Miljöarkeologiska laboratoriet. Umeå universitet, Humanistiska fakulteten, Humlab.
    SEAD - The Strategic Environmental Archaeology Database Inter-linking Multiproxy Environmental Data with Archaeological Investigations and Ecology2013Inngår i: Archaeology in the Digital Era: Papers from the 40th Annual Conference of Computer Applications and Quantitative Methods in Archaeology (CAA), Southampton, 26-29 March 2012 / [ed] Graeme Earl, Tim Sly, Angeliki Chrysanthi, Patricia Murrieta-Flores, Constantinos Papadopoulos, Iza Romanowska & David Wheatley, Amsterdam University Press, 2013, Vol. 1, s. 320-331Konferansepaper (Fagfellevurdert)
    Abstract [en]

    The volume of data on past environmental and climate changes, as well as human interactions with these, has long since passed the level where it is manageable outside of large scale database systems. The Strategic Environmental Archaeology Database project aims to not only store and disseminate such data, but also provide tools for querying and analysing them, whilst maintaining a close connection with the archaeological and ecological data that are essential for their comprehensive interpretation. Large scale, geographically and chronologically unrestricted databases provide us with essentially unlimited scope for putting individual sites into a broader context and applying locally collated data to the investigation of earth system level changes. By providing integrated access to data from a variety of proxies, including plant macrofossils, pollen, insects and geochemistry, along with dating evidence, more complex questions can be answered where any single proxy would not be able to provide comprehensive answers.

  • 67.
    Buckland, Philip I.
    et al.
    Umeå universitet, Humanistiska fakulteten, Institutionen för idé- och samhällsstudier, Miljöarkeologiska laboratoriet.
    Eriksson, Erik J.
    Umeå universitet, Humanistiska fakulteten, Institutionen för idé- och samhällsstudier, Miljöarkeologiska laboratoriet.
    Palm, Fredrik
    Umeå universitet, Humanistiska fakulteten, Humlab.
    SEAD - The Strategic Environmental Archaeology Database: Progress Report Spring 20142014Rapport (Annet vitenskapelig)
    Abstract [en]

    This report provides an overview of the progress and results of the VR:KFI infrastructure projects 2007-7494 and (825-)2010-5976. It should be considered as a status report in an on-going long-term research infrastructure development project.

  • 68.
    Buckland, Philip I.
    et al.
    Umeå universitet, Humanistiska fakulteten, Institutionen för idé- och samhällsstudier, Miljöarkeologiska laboratoriet.
    Linderholm, Johan
    Umeå universitet, Humanistiska fakulteten, Institutionen för idé- och samhällsstudier, Miljöarkeologiska laboratoriet.
    Östman, Sofi
    Umeå universitet, Humanistiska fakulteten, Institutionen för idé- och samhällsstudier, Miljöarkeologiska laboratoriet.
    Samuel, Ericson
    Umeå universitet, Humanistiska fakulteten, Institutionen för idé- och samhällsstudier, Miljöarkeologiska laboratoriet.
    Wallin, Jan-Erik
    Pollenlaboratoriet i Umeå AB.
    Engelmark, Roger
    Environmental archaeological analysis from the archaeological excavations at Ørland kampflybase, Vik 70/1, Ørland, Sør-Trøndelag, Norway. 2015-20162017Rapport (Annet vitenskapelig)
    Abstract [en]

    A total of 322 bulk samples, 267 bulk subsamples and 1632 survey samples from the excavation of Iron Age settlements at Ørland, Vik, Sør-Trondelag, were analysed at the Environmental Archaeology Laboratory (MAL) at Umeå University. The overall aim of these analyses was to look for evidence which could help identify possible prehistoric activity areas, understand building functions and divisions, and shed light on land management around the farmsteads.

  • 69.
    Bunnfors, Kalle
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten.
    Synthesis and electrochemical characterisation of processable polypyrrole boronic acid derivatives for carbohydrate binding2015Independent thesis Advanced level (degree of Master (Two Years)), 20 poäng / 30 hpOppgave
    Abstract [en]

    Conducting polymers have been widely explored for many different purposes including sensing. In thisthesis the conducive properties of pyrrole and the carbohydrate binding properties of boronic acid iscombined to make a reagent-free detector for carbohydrates. The polymer is manufactured in form ofparticles in the μm scale to create a porous film which has a high surface to volume ratio.The material was characterised and the binding properties were evaluated for galactose and glucose.Proof of binding was found via both electrochemical methods and QCM-D. A correlation between R2 value and concentration of substrate was found which enables measurement of concentration of carbohydratesin unknown samples.

  • 70.
    Buratovic, Sonja
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för organismbiologi, Miljötoxikologi.
    Low-Dose Ionizing Radiation Induces Neurotoxicity in the Neonate: Acute or fractionated doses and interaction with xenobiotics in mice2016Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    This thesis examines the developmental neurotoxic effects of exposure to low-dose ionizing radiation (IR), alone or together with xenobiotics, during a critical period of neonatal brain development in mice.

    During mammalian brain development there is a period called the brain growth spurt (BGS), which involves extensive growth and maturation of the brain. It is known that neonatal exposure during the BGS to xenobiotics can have a negative impact on neonatal brain development, resulting in impaired cognitive function in the adult mouse. In humans, the BGS starts during the third trimester of pregnancy and continues for approximately 2 years in the child.  

    The present thesis has identified a defined critical period, during the BGS, when IR can induce developmental neurotoxicity in mice. The observed neurotoxicity was not dependent on sex or strain and manifested as altered neurobehaviour in the adult mouse. Furthermore, fractionated dose exposures appear to be as potent as a higher acute dose. The cholinergic system can be a target system for developmental neurotoxicity of IR, since alterations in adult mouse cholinergic system susceptibility were observed. Co-exposure to IR and nicotine exacerbated the behavioural disturbances and cholinergic system dysfunction. Furthermore, co-exposure with the environmental agent paraquat has indicated that the dopaminergic system can be a potential target.  

    In this thesis, clinically relevant doses of IR and a sedative/anesthetic agent (ketamine) were shown to interact and exacerbate defects in adult mouse neurobehaviour, learning and memory, following neonatal exposure, at doses where the single agents did not have any impact on the measured variables. This indicates a shift in the dose-response curve for IR, towards lower doses, if exposure occurs during the neonatal brain development. In addition, co-exposed mice, showing cognitive defects, expressed elevated levels of tau protein in the cerebral cortex. Furthermore, exacerbation of neurochemical deviations were observed following co-exposure compared to irradiation alone.

    Further investigations of neurotoxic effects following fractionated or acute low-dose IR, modelling the clinical situation during repeated CT scans or levels of radiation deposited in non-target tissue during radiotherapy, and possible interaction effects with xenobiotics, is of great importance in the field of radioprotection. 

  • 71.
    Bélteky, Johan
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Chicken domestication: Effects of tameness on brain gene expression and DNA methylation2016Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    Domestication greatly increases phenotypic variation in a short time span, with selection for a single phenotype and a plethora of associated phenotypic changes as an outcome of the process. The domestication process influences the underlying genomic architecture of a species, and the success and speed of the process is likely influenced by it. The main aims of my thesis was to study how domestication affects the brain of chickens: specifically changes in morphology, gene expression, and DNA methylation. Differences in gene expression and DNA methylation between White Leghorn and Red Junglefowl chickens were mapped, and inheritance of these patterns were quantified, indicating a faithful transmission of breed-specific epigenetic markers. Selection on the behavioral trait fearfulness, generated high and low fearful lines of Red Junglefowl. Both the parental population and the fifth selected generation were used for the analyses in this thesis. One experiment studied morphological changes in the brain and other vital organs, and found that relative total brain size increased in high fearful birds, as a consequence of an increase in cerebral hemisphere size in high fearful birds and not in low fearful birds. Also, the relative heart, liver, spleen and testis size increased in high fearful birds, indicating correlated morphological changes with selection for fearfulness. Two additional experiments examined differential gene expression in the hypothalamus and the anterior cerebral hemisphere. The hypothalamus differed in expression of genes with reproductive and immunological functions, whilst the cerebral hemisphere differed in expression of genes related to social behaviors and neurological functions especially those upregulated in low fearful birds.  These results indicate the occurrence of tissue- and species-specific changes in gene expression as overlap with other domestication events were nearly nonexistent. A fourth experiment sought to associate the change in fear levels and gene expression differences with DNA methylation. Chromosomal regions with differential DNA methylation between high and low fearful birds were identified, and genes in these regions had annotated functions relevant to phenotypic differences between the selection lines. This thesis is the first to study the genetic alterations of domestication using the wild ancestor of an already domesticated species to repeat the domestication process selecting against fear of humans. The findings corroborate results from previous comparisons of wild and domestic animals, and further support the theory that rigorous selection for a behavioral trait can cause a cascade of genetic and epigenetic changes facilitating the domestication of a population.

  • 72.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Applied Fisheries Research at Karlstad University2007Konferansepaper (Fagfellevurdert)
  • 73.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Applied Fisheries Research in Southern Sweden2008Konferansepaper (Annet vitenskapelig)
  • 74.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Att arbeta med projekt i reglerade vattendrag2011Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 75.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Fish passage - Where do we stand today2012Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 76.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Förbättrad nedströmsvandring i Klarälven och andra vattendrag2011Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 77.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Förbättrad nedströmsvandring i Lyckebyån och andra vattendrag: Länsstyrelsen Blekinge. Lyckeby, 21 oktober, 2011.2012Annet (Annet (populærvitenskap, debatt, mm))
  • 78.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Passageproblem för fisk i reglerade vattendrag i södra Sverige2008Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 79.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Passageproblem för fisk i reglerade vattendrag i södra Sverige - Erfarenheter av restaurering från Emån och Ätran2008Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 80.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Re-establishing connectivity for fish populations in regulated rivers2006Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 81.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Rädda vandringsfisken!: Presentation för allmänheten vid Naturum Ronneby, 20 oktober, 20112011Annet (Annet (populærvitenskap, debatt, mm))
  • 82.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Salmon Rivers in Southern Sweden2007Konferansepaper (Fagfellevurdert)
  • 83.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Smolt migration in the River Klarälven, the importance of food.2006Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 84.
    Calles, Olle
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Ålens nedströmspassage av vattenkraftverk2008Konferansepaper (Annet vitenskapelig)
  • 85.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Alenäs, Ingemar
    Falkenbergs kommun.
    Tielman, Johan
    E.ON Vattenkraft.
    Rivinoja, Peter
    Institutionen för vilt, fisk och miljö. SLU, Umeå.
    Lindqvist, Krister
    Fiskens vandring i Ätran: Fiskvandringens dag – Living North Sea. The Interreg IVB North Sea Region Programme. Falkenberg, 20110514.2011Annet (Annet (populærvitenskap, debatt, mm))
  • 86.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Christiansson, Jonas
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper.
    Andersson, Jonas
    Sahlberg, Tony
    Stein, Florian
    University of Potsdam.
    Olsson, Britt-Marie
    Alenäs, Ingemar
    Falkenbergs kommun.
    Tielman, Johan
    E.ON Vattenkraft.
    Ål i Ätran: En fallstudie för svensk ålförvaltning2012Rapport (Annet vitenskapelig)
    Abstract [sv]

    Det europeiska ålbeståndet har minskat drastiskt under de senaste årtiondena och år 2007 antog därför EU en förordning, som innehåller åtgärder för återhämtning av beståndet av europeisk ål och som innebar att alla medlemsländer måste upprätta en nationell ålförvaltningsplan. I Sveriges ålförvaltningsplan anges minskad dödlighet i vattenkraftverk som en viktig åtgärd för att öka mängden blankålar som når havet. För att sådana åtgärder ska få stor effekt, måste man veta var mest ål produceras och vilken skada som orsakas av de kraftverk ålen passerar på sin väg mot havet. Denna kunskap är bristfällig för de flesta vattendrag i Sverige.

    Ätran har en lång historia som ett ålproducerande vattendrag soch lämpar sig väl för en fallstudie för svensk ålförvaltning för att belysa ålproduktionens omfattning, dess lokalisering och därmed åtgärdsnyttan. Blankålsfångst på sex platser i Ätrans avrinningsområde under 2010-2011 visade att Ätran prducerar minst 950 blankålar/år och den totala produktionen för hela Åtrans avrinningsområde skulle kunna vara >5500 blankålar/år. Vår studie visar att man utöver redan genomförda och beslutade åtgärder endast behöver åtgärda ytterligare ett kraftverk för att merparten av Åtyrans blankålar ska nå havet.

  • 87.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Greenberg, Larry
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Evaluating fishway function in a regulated river2005Konferansepaper (Fagfellevurdert)
  • 88.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Greenberg, Larry
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Evaluating the effectiveness of bypass channels in a regulated river2003Konferansepaper (Fagfellevurdert)
  • 89.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Greenberg, Larry
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Fishways in regulated rivers: Consequences of a remedial measure for a stream’s productivity2002Konferansepaper (Fagfellevurdert)
  • 90.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Greenberg, Larry
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Fiskvandringsproblematik i Emån och Ätran2008Konferansepaper (Annet vitenskapelig)
  • 91.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Greenberg, Larry
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Rivinoja, Peter
    Institutionen för vilt, fisk och miljö. SLU, Umeå.
    A historical perspective on downstream passage at hydroelectric plants in Swedish rivers2013Inngår i: Ecohydraulics: an integrated approach / [ed] Ian Maddock, Atle Harby, Paul Kemp and Paul Wood, West Sussex, UK: John Wiley & Sons, 2013, 1, s. 309-322Kapittel i bok, del av antologi (Fagfellevurdert)
  • 92.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Karlsson, Simon
    School of Civil Engineering & Environment, University of Southampton.
    Hebrand, Mats
    Fiskevårdsteknik AB, Pålsjövägen 12, S-223 62 Lund, Sverige.
    Comoglio, Claudio
    DITAG—Land, Environment and Geo-Engineering Department, Politecnico di Torino, Italy.
    Evaluating technical improvements for downstream migrating diadromous fish at a hydroelectric plant2012Inngår i: Ecological Engineering - The Journal of Ecosystem Restoration, ISSN 0925-8574, Vol. 48, s. 30-37Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Technical improvements to ameliorate downstream passage for diadromous fish have rarely been eval-uated in regulated rivers in northern Europe. The current study evaluated rehabilitative measures for downstream migrating Atlantic salmon, brown trout and European eel at a hydroelectric plant in south-ern Sweden. Smolts (

    N= 66), kelts (N= 20) and silver eels (N= 55) were caught, radio-tagged and tracked whilst passing the facilities in spring (salmonids) and fall (eels) of 2007. A surface gate in combination with a 90 mm-spaced turbine intake rack had a fish guidance efficiency ranging from no effect for eels and trout smolts to 50% for trout kelts. A siphon discharging water from the bottom of the same 90 mm rack did not bypass any tagged fish, and only a few untagged eels. The poor function of the measures was attributed to the failure of the rack to stop smolts and eels from entering the turbines. The kelts, on the other hand, could not pass through the rack, and instead took a long time to locate the surface bypass entrance. The conditions for downstream migrating fish have improved at the hydroelectric plant, but the total losses remain quite high for the studied groups (10–67%), and there is a need for a new rehabilitative measure that effectively allows all fish to bypass the turbines.

  • 93.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Rivinoja, Peter
    Institutionen för vilt, fisk och miljö. SLU, Umeå.
    Upp & Nedströms Passage - Nuläget & Framtida Möjligheter2011Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 94.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Stein, Florian
    University of Potsdam.
    Sahlberg, Tony
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Christiansson, Jonas
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Olsson, Britt-Marie
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Tielman, Johan
    E.ON Vattenkraft.
    Alenäs, Ingemar
    Falkenbergs kommun.
    Åtgärder för nedströmsvandrande fisk i reglerade vattendrag2012Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 95.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Tielman, Johan
    E.ON Vattenkraft.
    Alenäs, Ingemar
    Falkenbergs kommun.
    Comoglio, Claudio
    DITAG—Land, Environment and Geo-Engineering Department, Politecnico di Torino.
    Greenberg, Larry
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Rehabilitating the River Ätran for diadromous fish species2010Konferansepaper (Fagfellevurdert)
  • 96.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Tielman, Johan
    E.ON Vattenkraft.
    Alenäs, Ingemar
    Falkenbergs kommun.
    Hebrand, Mats
    Fiskevårdsteknik AB, Pålsjövägen 12, S-223 62 Lund.
    Lindqvist, Krister
    Monitoring Migratory Fish in the River Ätran2011Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 97.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Tielman, Johan
    E.ON Vattenkraft.
    Alenäs, Ingemar
    Falkenbergs kommun.
    Hebrand, Mats
    Fiskevårdsteknik AB, Pålsjövägen 12, S-223 62 Lund.
    Lindqvist, Krister
    Sex års fiskforskning i Ätran - Implikationer för förvaltningen: Hur mår Ätran?2012Konferansepaper (Annet (populærvitenskap, debatt, mm))
  • 98.
    Calles, Olle
    et al.
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Österling, Martin
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Gustafsson, Stina
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Rees, Nina
    Karlstads universitet, Fakulteten för samhälls- och livsvetenskaper, Avdelningen för biologi.
    Ett riktigt ålamörker: Barnens universitet, Karlstads universitet, 17 oktober 2011.2011Annet (Annet (populærvitenskap, debatt, mm))
  • 99.
    Carlsson, Tomas
    Utförare miljöövervakning, Länsstyrelser, lst, Länsstyrelsen Gävleborg.
    Naturinventering av Holmarna inom Ljusdals kommun1976Rapport (Annet vitenskapelig)
    Abstract [sv]

    Föreliggande arbete gäller naturinventering av Holmarna inom Ljusdal kommun.

    Uppdragsgivare har varit länsstyrelsen i Gävleborgs län.

    Målsättningen vid inventeringen har varit att undersöka Holmarnas flora och fauna samt att ge förslag till området skötsel.

    Fältarbetet har utförts under maj-juni 1976 och sammanställningen gjordes under juli-september 1976.

  • 100.
    Caspillo, Nasim Reyhanian
    Södertörns högskola, Institutionen för naturvetenskap, miljö och teknik, Biologi. Örebro universitet.
    Hitting the mark: Studies of alterations in behaviour and fertility in ethinyl estradiol-exposed zebrafish and search related biomarkers2016Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    In this thesis, we have analysed the effects of EE2 on non-reproductive behaviours and fertility. We have showed that two doses of EE2 in male adult short-term exposures evokes opposite behaviours in the novel tank test. A lower dose induced increased bottom-dwelling, a sign of increased anxiety and a higher dose increased surface-dwelling, which would likely expose themselves to predation in a natural environment. Increased shoaling was observed in both exposures, possibly affecting feeding and reproduction opportunities. Fertility analysis of these fish demonstrated a complete inhibition of spawning in the highest dose group. To investigate mechanisms behind the spawning failure, we examined expression levels of genes involved in zebrafish sex differentiation and maintenance of gonadal function. We found downregulated transcription levels of male-predominant genes, suggesting a demasculinization of the testes contributing to functional sterility in these fish. We have demonstrated that non-reproductive behaviour in zebrafish is highly sensitive to EE2 exposure during development. After exposing male and female zebrafish to low doses of EE2 followed by remediation in clean water until adulthood, the fish displayed increased anxiety and shoaling behaviour, demonstrating persistent effects of EE2. Furthermore, behavioural effects were transferred to their progeny. Decreased fertilisation success of the developmentally exposed fish was observed in both sexes when mated to untreated animals of the opposite sex. These fertility effects persisted although the fish had a long remediation period, implying likely reduced fitness of fish populations in aquatic environments. Based on our findings on non-reproductive behaviours and fertility, we performed RNAsequencing analysis of the brain and testes in order to investigate possible biological mechanisms behind the persistent effects. There is a need for biomarkers allowing detection of both reversible and irreversible effects in animals exposed to estrogenic substances, hopefully contributing to better risk assessments for EDCs. Results from RNA-sequencing would serve as a basis for continued studies in pursuit of potential biomarkers.

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