Change search
Refine search result
35363738394041 1851 - 1900 of 1156728
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rows per page
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sort
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
Select
The maximal number of hits you can export is 250. When you want to export more records please use the Create feeds function.
  • 1851. Aalto-Setälä, Katriina
    et al.
    Palomäki, Heikki
    Miettinen, Helena
    Vuorio, Alpo
    Kuusi, Timo
    Raininko, Raili
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology.
    Salonen, Oili
    Kaste, Markku
    Kontula, Kimmo
    Genetic risk factors and ischemic cerebrovascular disease: role of common variation of the genes encoding apolipoproteins and angiotensin-converting enzyme1998In: Annals of Medicine, ISSN 0785-3890, E-ISSN 1365-2060, Vol. 30, no 2, p. 224-33Article in journal (Refereed)
    Abstract [en]

    DNA polymorphisms in genes encoding apolipoproteins (apo) A-I, C-III, B and E and angiotensin-converting enzyme (ACE) have been proposed to be associated with the risk of coronary artery disease (CAD). We studied whether the same genetic markers would also be associated with the occurrence and extent of atherosclerosis in cervical arteries. DNA samples from 234 survivors of stroke or a transient ischaemic attack aged 60 years or less were examined. The presence of atherosclerosis was assessed using aortic arch angiograms. The SstI polymorphism of apoA-I/C-III gene locus, the XbaI polymorphism of apoB gene, common apoE phenotypes and the insertion/deletion polymorphism of the ACE gene were analysed. The allele frequencies of the apoA-I/C-III, apoB, apoE or ACE gene did not differ between the groups with (n = 148) or without (n = 85) cervical atherosclerosis. However, when patients with at least one apoE4 allele and one X2 allele of apoB were combined and compared with those without either of them (E2E3 or E3E3 and X1X1), a significant association with the presence of cervical atherosclerosis was found (P = 0.03). The patients having the E2E3 phenotype had a significantly elevated serum triglyceride level compared with those with the E3E3 phenotype (P = 0.03). Serum high-density lipoprotein (HDL) cholesterol was lower in the patients with the E2E3 phenotype than in those with the E3E3 and E3E4 (P = 0.01 and P = 0.06, respectively). The apoB or ACE genotypes were not significantly associated with serum lipid or lipoprotein levels. There was no association between the ACE gene polymorphism and the occurrence of hypertension. In conclusion, the interaction of common apoB and apoE alleles may increase the risk of atherosclerosis in cervical arteries.

  • 1852.
    Aamaas, Borgar
    et al.
    Ctr Int Climate & Environm Res Oslo, N-0318 Oslo, Norway.;Univ Oslo, UiO, N-0316 Oslo, Norway.;UNIS, Univ Ctr Svalbard, N-9171 Longyearbyen, Norway..
    Boggild, Carl Egede
    UNIS, Univ Ctr Svalbard, N-9171 Longyearbyen, Norway..
    Stordal, Frode
    Univ Oslo, UiO, N-0316 Oslo, Norway..
    Berntsen, Terje
    Ctr Int Climate & Environm Res Oslo, N-0318 Oslo, Norway.;Univ Oslo, UiO, N-0316 Oslo, Norway..
    Holmen, Kim
    UNIS, Univ Ctr Svalbard, N-9171 Longyearbyen, Norway.;Polar Environm Ctr, NPI, N-9296 Tromso, Norway..
    Ström, Johan
    Stockholm Univ, S-10691 Stockholm, Sweden.;Polar Environm Ctr, NPI, N-9296 Tromso, Norway..
    Elemental carbon deposition to Svalbard snow from Norwegian settlements and long-range transport2011In: Tellus. Series B, Chemical and physical meteorology, ISSN 0280-6509, E-ISSN 1600-0889, Vol. 63, no 3, p. 340-351Article in journal (Refereed)
    Abstract [en]

    The impact on snow pack albedo from local elemental carbon (EC) sources in Svalbard has been investigated for the winter of 2008. Highly elevated EC concentrations in the snow are observed around the settlements of Longyearbyen and Svea (locally > 1000 ng g(-1), about 200 times over the background level), while EC concentrations similar to the background level are seen around Ny-Alesund. Near Longyearbyen and Svea, darkened snow influenced by wind transported coal dust from open coal stockpiles is clearly visible from satellite images and by eye at the ground. As a first estimate, the reduction in snow albedo caused by local EC pollution from the Norwegian settlements has been compared to the estimated reduction caused by long-range transported EC for entire Svalbard. The effect of local EC from Longyearbyen, Svea and all Norwegian settlements are estimated to 2.1%, 7.9% and 10% of the total impact of EC, respectively. The EC particles tend to stay on the surface during melting, and elevated EC concentrations due to the spring melt was observed. This accumulation of EC enhances the positive albedo feedbacks. The EC concentrations were observed to be larger in metamorphosed snow than in fresh snow, and especially around ice lenses.

  • 1853. Aamaas, Borgar
    et al.
    Boggild, Carl Egede
    Stordal, Frode
    Berntsen, Terje
    Holmen, Kim
    Ström, Johan
    Stockholm University, Faculty of Science, Department of Applied Environmental Science (ITM).
    Elemental carbon deposition to Svalbard snow from Norwegian settlements and long-range transport2011In: Tellus. Series B, Chemical and physical meteorology, ISSN 0280-6509, E-ISSN 1600-0889, Vol. 63, no 3, p. 340-351Article in journal (Refereed)
    Abstract [en]

    The impact on snow pack albedo from local elemental carbon (EC) sources in Svalbard has been investigated for the winter of 2008. Highly elevated EC concentrations in the snow are observed around the settlements of Longyearbyen and Svea (locally > 1000 ng g(-1), about 200 times over the background level), while EC concentrations similar to the background level are seen around Ny-Alesund. Near Longyearbyen and Svea, darkened snow influenced by wind transported coal dust from open coal stockpiles is clearly visible from satellite images and by eye at the ground. As a first estimate, the reduction in snow albedo caused by local EC pollution from the Norwegian settlements has been compared to the estimated reduction caused by long-range transported EC for entire Svalbard. The effect of local EC from Longyearbyen, Svea and all Norwegian settlements are estimated to 2.1%, 7.9% and 10% of the total impact of EC, respectively. The EC particles tend to stay on the surface during melting, and elevated EC concentrations due to the spring melt was observed. This accumulation of EC enhances the positive albedo feedbacks. The EC concentrations were observed to be larger in metamorphosed snow than in fresh snow, and especially around ice lenses.

  • 1854.
    Aaman, Sophia
    et al.
    KTH, School of Industrial Engineering and Management (ITM).
    Hessel Lundberg, Johan Henrik
    KTH, School of Industrial Engineering and Management (ITM).
    Setting the seeds for a green growth -A Study of biofuel development in Indonesia’s transport sector2017Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 1855.
    Aamand Grabau, Dorthe
    et al.
    Skåne University Hospital, Sweden .
    Bendahl, Par-Ola
    Lund University, Sweden .
    Ryden, Lisa
    Lund University, Sweden .
    Stål, Olle
    Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Center for Surgery, Orthopaedics and Cancer Treatment, Department of Oncology.
    Ferno, Marten
    Lund University, Sweden .
    The prevalence of immunohistochemically determined oestrogen receptor positivity in primary breast cancer is dependent on the choice of antibody and method of heat-induced epitope retrieval - prognostic implications?2013In: Acta Oncologica, ISSN 0284-186X, E-ISSN 1651-226X, Vol. 52, no 8, p. 1657-1666Article in journal (Refereed)
    Abstract [en]

    Background. Oestrogen receptor (ER) status is important for the choice of systemic treatment of breast cancer patients. However, most data from randomised trials on the effect of adjuvant endocrine therapy according to ER status are based on the cytosol methods. Comparisons with immunohistochemical methods have given similar results. The aim of the present study was to examine whether different ER antibodies and heat-induced epitope retrieval (HIER) methods influence the prevalence of ER-positivity in primary breast cancer. Material and methods. This study is based on patients included in a clinical trial designed to compare the effect of two years of adjuvant tamoxifen versus no adjuvant systemic treatment in premenopausal women. From 1986 to 1991, 564 patients from two study centres in Sweden were enrolled and randomised. Patients were randomised independently of ER status. In the present study, ER status was assessed on tissue microarrays with the three different ER antibody/HIER combinations: 1D5 in citrate pH 6 (n = 390), SP1 in Tris pH 9 (n = 390) and PharmDx in citrate pH 6 (n = 361). Results. At cut-offs of 1% and 10%, respectively, the prevalence of ER-positivity was higher with SP1 (75% and 72%) compared with 1D5 (68% and 66%) and PharmDx (66% and 62%). At these cut-offs, patients in the discordant groups (SP1-positive and 1D5-negative) seem to have a prognosis intermediate between those of the double-positive and double-negative groups. Comparison with the ER status determined by the cytosol-based methods in the discordant group also showed an intermediate pattern. The repeatability was good for all antibodies and cut-offs, with overall agreement andgt;= 93%. Conclusion. The present study shows that the choice of antibody and HIER method influences the prevalence of ER-positivity. We suggest that this be taken into consideration when choosing a cut-off for clinical decision making.

  • 1856.
    Aamir, Suhaib
    et al.
    Umeå University, Faculty of Social Sciences, Umeå School of Business.
    Farooq, Umar
    Umeå University, Faculty of Social Sciences, Umeå School of Business.
    Assessing the Preparedness of Small and Medium-sized Entities in Sweden: to Adopt International Financial Reporting Standard (IFRS) for Small and Medium-sized Entities (SMEs).2010Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    SMEs serve as a backbone to keep an economy going and to boost it up in times of difficult hours like recession, for example. They are considered as the main source of modernization, innovation and entrepreneurial spirit. Like rest of Europe, 99% of enterprises are SMEs in Sweden which form a ratio of approximately 58 SMEs per 1000 inhabitants. Moreover SMEs employ around 60% of Sweden‟s manpower which shows their concern toward social responsibility.

    Several companies irrespective of their size are bound by the statutory rules of a particular country in which they operate to prepare financial reports that conform to specified set of accounting principles. There has been much ongoing debate regarding the suitability of one set of accounting standards in a country for all its operating enterprises, regardless of their size. In July 2009 the International Accounting Standards Board (IASB) published the International Financial Reporting Standard (IFRS) for Small and Medium-sized Entities (SMEs). The IFRS for SMEs is intended to be applied to the general purpose financial statements of entities that do not have public accountability. The main theme of our thesis is to examine the suitability and difficulties faced by SMEs in Sweden towards IFRS for SMEs. Furthermore, this thesis will identify the problems that will be faced by SMEs in Sweden, in the process of adopting IFRS for SMEs. Lastly, this study will be conducted to check whether SMEs in Sweden prefer to choose and use IFRS for SMEs or Swedish GAAP.

    In order to achieve the determined objectives, the study "Assessing the preparedness of small and medium-sized entities in Sweden to adopt International Financial Reporting Standard (IFRS) for Small and Medium-sized Entities (SMEs)" was conducted. A qualitative research employing semi-structured interviews was carried out with eleven interviews in order to solidify the quality criteria of our research work. Sample was selected based on convenient sampling from Umeå due to the limitations of resources in terms of cost and time; opinions from three different categories of respondents (audit firms, SMEs and experts‟ opinion from the academic perspective) would be gathered. All collected data would be analyzed against the theoretical framework, and with the help of analysis conclusion regarding this study would be drawn.

    Based on the qualitative results, the findings exhibits that SMEs in Sweden are not inclined towards IFRs for SMEs and are not ready in any way to adopt these standards. The Swedish GAAP has been designed over years and all SMEs are very much familiar with the rules and principles applicable in Swedish GAAP. Therefore, according to our research inclination of SMEs in Sweden is towards Swedish GAAP rather than IFRS for SMEs.

  • 1857.
    Aamir, Suhaib
    et al.
    Umeå University, Faculty of Social Sciences, Umeå School of Business.
    Farooq, Umar
    Umeå University, Faculty of Social Sciences, Umeå School of Business.
    Auditor client relationship and audit Quality: The effects of long-term auditor client relationship on audit quality in SMEs2011Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Different scandals around the globe during the past, in specific during the last decade, have intrigued the stakeholders to question the roles of both auditors and management. But most of the fingers since then have been raised on the role of auditors, because it is the auditors who are entrusted with the responsibility to detect any errors or frauds in the financial reports of the client-firm. Apart from this, the long-term auditor client relationship has been the center of attention in most of the discussions and debates as well. Numerous studies have been conducted by the academic researchers, financial and professional analysts, regulatory authorities and governing bodies, and in some cases by the auditors and the firms as well regarding the effects of long-term auditor-client relationship on audit quality, equity risk premium, financial reports quality, audit pricing etc. These studies provide us with different results, both with the positive and negative associations and effects of long-term auditor-client relationship on the basis of different factors and contexts.

    For long, auditing has been discussed in different studies and research areas but mostly in association with publicly listed companies. Less attention has been paid to the relationship of auditors and clients as far as clients in SMEs are concerned. In any country around the globe, SMEs are of major contribution in terms of backing the economy, giving it both the boost and the stability, as they collectively form the major chunk of the economy. If we specify our study to the SMEs in Sweden, then 99% of the enterprises in Sweden represent the SME sector; in addition they employ around 60% of the manpower. Based on these facts, and due to less attention given to auditor-client relationship in terms of SMEs, instead of; we have directed our concerns towards the study of effects of auditor-client relationship on audit quality in SMEs in this particular research study.

    In this study, we have opted for qualitative research with semi-structured interviews to be used as the tool for data collection. Interviews were conducted with two different groups of interviewees, one group representing the auditors and the other group representing the client-firms (SMEs). A total of seven interviews were conducted in order to strengthen and validate the results for our research question. Due to the limitations of this study, mostly in terms of cost and time, samples were selected from Umeå, Sweden. The data interview structure, data analysis and discussion, and conclusions were all made based on existing theories summarized in the theoretical review of this study. The results of this study suggests that (1) long-term audit tenure is beneficial for the audit quality if certain risk factors like risk of auditor independence and risk of developing complacency are controlled; and (2) factors such as NAS, industry specialization, knowledge and experience of the auditor, internal control in the client-firm, professional ethics, proper audit plan, providence of unbiased information by the client, and appointment of the auditor by the client-firm itself enhances the audit quality.

  • 1858.
    Aamir, Syed Ahmed
    Linköping University. Linköping University, Department of Electrical Engineering.
    A 65nm, Low Voltage, Fully Differential, SC Programmable Gain Amplifier for Video AFE2010Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    Due to rapid growth of home entertainment consumer market, video technology has been continuously pushed to deliver sharper pictures with higher resolution. This has brought about stringent requirements on the video analog front end, which often coupled with the low power and low voltage regulations had to deal with short channel effects of the deep submicron CMOS processes.

    This thesis presents the design of a fully differential programmable gain amplifier, as a subcircuit of a larger video digitizing IC designed at division of Electronic Systems. The switched capacitor architecture of the PGA does not only buffer the signal, but performs compensation for the sync-tip of analog video signal.

    The pseudo differential OTA eliminates tail current source and maintains high signal swing and has efficient common mode feedforward mechanism. When coupled with a similar stage provides inherent common moode feedback without using an additional SC-CMFB block.

    The PGA has been implemented using a 65 nm digital CMOS process. Expected difficulties in a 1.2 V OTA design make themselves evident in 65 nm, which is why cascaded OTA structures were inevitable for attaining gain specification of 60 dB. Nested Miller compensation with a pole shifting source follower, stabilizes the multipole system. The final circuit attains up to 200 MHz bandwidth and maintains high output swing of 0.85 V. High slew rate and good common mode and power supply rejection are observed. Noise requirements require careful design of input differential stage. Although output source follower stabilized the system, it reduces significant bandwidth and adds to second order non-linearity.

  • 1859.
    Aamir, Syed Ahmed
    et al.
    Linköping University, Department of Electrical Engineering, Electronics System. Linköping University, The Institute of Technology.
    Wikner, J Jacob
    Linköping University, Department of Electrical Engineering, Electronics System. Linköping University, The Institute of Technology.
    A 1.2-V pseudo-differential OTA with common-mode feedforward in 65-nm CMOS2010In: Proceedings of the 17th IEEE International Conference on Electronics, Circuits, and Systems, Institute of Electrical and Electronics Engineers (IEEE), 2010, p. 29-32Conference paper (Refereed)
    Abstract [en]

    In this work, we describe the implementation of a 1. 2-V pseudo-differential operational transconductance amplifier (OTA) with common-mode feedforward (CMFF) and inher­ent common-mode feedback (CMFB) in a 65-nm, digital CMOS process. The OTA architecture provides an inher­ent CMFB when cascaded OTA structures are utilized andthis work has studied a cascaded amplifier consisting of fourstages. Due to the low-gain using core 65-nm circuit de­vices, the overall gain must be distributed on all four stages to acquire a gain of more than 60 dB, while maintaining a-3-dB bandwidth of 200 MHz. To achieve high gain, we propose using a modified, positive-feedback, cross-coupled input differential stage. The modified OTA achieves a high output swing of ± 0.85 V due to only two stacked transistors, 88 dB DC gain and a third-order harmonic of -60 dB for 800 mVpp at 30 MHz. Further on, in a capacitive buffer configuration, we achieve a high slew rate of 1240 V/µS, -3-dB bandwidth of 509 MHz, signal-to-noise ratio of 63 dB while consuming 10.4 mW power.

  • 1860.
    Aamir, Syed Ahmed
    et al.
    Linköping University, Department of Electrical Engineering, Electronics System. Linköping University, The Institute of Technology.
    Wikner, J Jacob
    Linköping University, Department of Electrical Engineering, Electronics System. Linköping University, The Institute of Technology.
    A 500-MHz low-voltage programmable gain amplifier for HD video in 65-nm CMOS2010In: Proceedings of 28th IEEE Norchip Conference., NORCHIP'10, Tampere: www.ieee.org , 2010, p. 1-4Conference paper (Refereed)
    Abstract [en]

    This work describes the implementation of a 1.2-V programmable gain amplifier (PGA) for high-definition (HD) video digitizers in a 65-nm digital CMOS process. The “pseudo” switched-capacitor (SC) PGA architecture buffers the video signal, without switching, during the active video. The SC circuitry is used for setup of DC operating point during horizontal and vertical blanking periods. Additionally, it compensates for the `sync-tip' of analog video signals to an equal blanking level for increased dynamic range to the digitizer following the PGA. The operational transconductance amplifier (OTA) employed as main amplifier in the PGA is a pseudo-differential, positive-feedback input stage architecture with a common-mode feedforward (CMFF) technique. The common-mode feedback (CMFB) is provided once two OTAs are cascaded. Schematic-level simulation results show that the OTA maintains a -3-dB bandwidth of 550 MHz, while keeping the distortion HD3 at -60 dB for a 30-MHz, 850 mVpp high definition video signal. The 88 dB DC gain is distributed among four OTA stages and the overall, combined PGA achieves a signal-to-noise ratio of 63 dB. Due to only two stacked transistors, it achieves high output swing of ±0.85 V, 1240 V/μs slew rate while consuming 10.4 mW power.

  • 1861.
    AAMIR, ZEESHAN
    Dalarna University, School of Technology and Business Studies, Computer Engineering.
    Developing a Communication link between Agents and cross Platform IDE2010Independent thesis Advanced level (degree of Master (Two Years))Student thesis
    Abstract [en]

    The main objective of this thesis work is to develop communication link between Runrev Revolution (IDE) and JADE (Multi-Agent System) through Socket programming using TCP/IP layer. These two independent platforms are connected using socket programming technique. Socket programming is considered to be newly emerging technology among these two platforms, the work done in this thesis work is considered to be a prototype. A Graphical simulation model is developed by salixphere (Company in Hedemora) to simulate logistic problems using Runrev Revolution (IDE). The simulation software/program is called “BIOSIM”. The logistic problems are complex, and conventional optimization techniques are unlikely very successful. “BIOSIM” can demonstrate the graphical representation of logistic problems depending upon the problem domains. As this simulation model is developed in revolution programming language (Transcript) which is dynamically typed and English-like language, it is quite slow compared to other high level programming languages. The object of this thesis work is to add intelligent behaviour in graphical objects and develop communication link between Runrev revolution (IDE) and JADE (Multi-Agent System) using TCP/IP layers. The test shows the intelligent behaviour in the graphical objects and successful communication between Runrev Revolution (IDE) and JADE (Multi-Agent System).

  • 1862. Aamodt, A.
    et al.
    Gundersen, O. E.
    Loge, J. H.
    Wasteson, Elisabet
    Mid Sweden University, Faculty of Human Sciences, Department of Social Sciences.
    Szczepanski, T.
    Case-based reasoning for assessment and diagnosis of depression in palliative care2010In: Proceedings - IEEE Symposium on Computer-Based Medical Systems, 2010, p. 480-485Conference paper (Refereed)
    Abstract [en]

    The goal of the research presented is to create a computational framework and system architecture for clinical decision support in palliative care. The application focused is the classification of depression. The method under investigation is case-based reasoning, motivated by the complexity of the domain and a lack of generalized principles of sufficient coverage and strength for diagnosis and treatment. A system architecture is described and exemplified through an implemented prototype. The outcome of the research so far is a system that captures the properties intended, and for which a clinical test set-up has been defined. © 2010 IEEE.

  • 1863.
    Aamodt, Ina Thon
    et al.
    Oslo Univ Hosp Ulleval, Norway; Univ Oslo, Norway.
    Lycholip, Edita
    Vilnius Univ, Lithuania.
    Celutkiene, Jelena
    Vilnius Univ, Lithuania.
    Strömberg, Anna
    Linköping University, Department of Medical and Health Sciences, Division of Nursing Science. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Heart and Medicine Center, Department of Cardiology in Linköping.
    Atar, Dan
    Oslo Univ Hosp, Norway; Univ Oslo, Norway.
    Falk, Ragnhild Sorum
    Oslo Univ Hosp, Norway.
    von Lueder, Thomas
    Oslo Univ Hosp, Norway.
    Helleso, Ragnhild
    Univ Oslo, Norway.
    Jaarsma, Tiny
    Linköping University, Department of Social and Welfare Studies, Division of Nursing Science. Linköping University, Faculty of Medicine and Health Sciences.
    Lie, Irene
    Oslo Univ Hosp Ulleval, Norway.
    Health Care Professionals Perceptions of Home Telemonitoring in Heart Failure Care: Cross-Sectional Survey2019In: Journal of Medical Internet Research, ISSN 1438-8871, E-ISSN 1438-8871, Vol. 21, no 2, article id e10362Article in journal (Refereed)
    Abstract [en]

    Background: Noninvasive telemonitoring (TM) can be used in heart failure (HF) patients to perform early detection of decompensation at home, prevent unnecessary health care utilization, and decrease health care costs. However, the evidence is not sufficient to be part of HF guidelines for follow-up care, and we have no knowledge of how TM is used in the Nordic Baltic region. Objective: The aim of this study was to describe health care professionals (HCPs) perception of and presumed experience with noninvasive TM in daily HF patient care, perspectives of the relevance of and reasons for applying noninvasive TM, and barriers to the use of noninvasive TM. Methods: A cross-sectional survey was performed between September and December 2016 in Norway and Lithuania with physicians and nurses treating HF patients at either a hospital ward or an outpatient clinic. A total of 784 questionnaires were sent nationwide by postal mail to 107 hospitals. The questionnaire consisted of 43 items with close- and open-ended questions. In Norway, the response rate was 68.7% (226/329), with 57 of 60 hospitals participating, whereas the response rate was 68.1% (310/455) in Lithuania, with 41 of 47 hospitals participating. Responses to the closed questions were analyzed using descriptive statistics, and the open-ended questions were analyzed using summative content analysis. Results: This study showed that noninvasive TM is not part of the current daily clinical practice in Norway or Lithuania. A minority of HCPs responded to be familiar with noninvasive TM in HF care in Norway (48/226, 21.2%) and Lithuania (64/310, 20.6%). Approximately half of the HCPs in both countries perceived noninvasive TM to be relevant in follow-up of HF patients in Norway (131/226, 58.0%) and Lithuania (172/310, 55.5%). For physicians in both countries and nurses in Norway, the 3 most mentioned reasons for introducing noninvasive TM were to improve self-care, to reduce hospitalizations, and to provide high-quality care, whereas the Lithuanian nurses described ability to treat more patients and to reduce their workload as reasons for introducing noninvasive TM. The main barriers to implement noninvasive TM were lack of funding from health care authorities or the Territorial Patient Fund. Moreover, HCPs perceive that HF patients themselves could represent barriers because of their physical or mental condition in addition to a lack of internet access. Conclusions: HCPs in Norway and Lithuania are currently nonusers of TM in daily HF care. However, they perceive a future with TM to improve the quality of care for HF patients. Financial barriers and HF patients condition may have an impact on the use of TM, whereas sufficient funding from health care authorities and improved knowledge may encourage the more widespread use of TM in the Nordic Baltic region and beyond.

  • 1864. Aamotsbakken, Bente
    Christoffer Dahl, Litteraturstudiets legitimeringar. En analys av skrift och bild i fem läromedel i svenska för gymnasieskolan. Institutionen för litteratur, idéhistoria och religion, Göteborgs universitet. Göteborg 20152016In: Samlaren: tidskrift för svensk litteraturvetenskaplig forskning, ISSN 0348-6133, E-ISSN 2002-3871, Vol. 137, p. 222-229Article, book review (Other academic)
  • 1865.
    Aanaes, K
    et al.
    Rigshosp, Denmark .
    Rasmussen, N
    Rigshosp, Denmark Statens Serum Institute, Denmark .
    Pressler, T
    Rigshosp, Denmark Rigshosp, Denmark .
    Segelmark, Mårten
    Linköping University, Department of Medical and Health Sciences, Pharmacology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Centre, Department of Nephrology UHL.
    Johansen, H K
    Rigshosp, Denmark .
    Lindberg, U
    Lund University, Sweden .
    Hoiby, N
    Rigshosp, Denmark .
    Carlsson, M
    Lund University, Sweden .
    Wieslander, J
    EuroDiagnostica AB, Sweden .
    Buchwald, C
    Rigshosp, Denmark .
    Extensive Endoscopic Image-Guided Sinus Surgery Decreases BPI-ANCA in Patients with Cystic Fibrosis2012In: Scandinavian Journal of Immunology, ISSN 0300-9475, E-ISSN 1365-3083, Vol. 76, no 6, p. 573-579Article in journal (Refereed)
    Abstract [en]

    Antineutrophil cytoplasm autoantibodies (ANCA) directed against bactericidal/permeability-increasing protein (BPI) are common in patients with cystic fibrosis (CF), and serum levels are correlated with lung colonization by Pseudomonas aeruginosa and the severity of lung damage. The production of BPI-ANCA may be due to the costimulation of BPI when mounting an immune response against P. aeruginosa. The effect of surgery aiming to eradicate bacteria and infected tissue on BPI-ANCA levels is sparsely described. A cohort of patients with CF were included: 53 patients having extensive image-guided sinus surgery (EIGSS) with topical postoperative antibiotic treatment, 131 non-operated controls and 36 who had double lung transplantation (LTX). In all 219 patients, serum samples before and after surgery or at similar intervals were analysed for IgG and IgA BPI-ANCA. The EIGSS group showed a highly significant decrease in both IgA and IgG BPI-ANCA levels compared with their own preoperative values and control group values (P andlt; 0.0010.02). The LTX patients also showed a highly significant decrease in both IgA and IgG BPI-ANCA levels (P andlt; 0.001). EIGSS and LTX decrease IgA and IgG BPI-ANCA levels in patients with CF, indicating that extensive removal of infected tissue influences the pathogenic process of autoantibody production. The results shown herein are in favour of applying EIGSS in selected patients with CF and for using BPI-ANCA as a surrogate marker for guiding further therapeutic interventions.

  • 1866.
    Aandahl, Hanna
    Blekinge Institute of Technology, School of Planning and Media Design.
    Tryggare Park: Åtgärdsförslag för Kroksbäcksparken ur ett trygghetsperspektiv2011Independent thesis Advanced level (degree of Master (One Year))Student thesis
    Abstract [sv]

    Kan trygghet skapas? Trygghetsfrågorna har fått ett allt större utrymme i debatten om staden. Forskningen och debatten är långt ifrån entydig och recepten på trygghet varierar kraftigt mellan olika länder. Grovt kan de förespråkade åtgärderna delas in i två läger: säkerhet och trygghet. ”Säkerhet” med framför allt situationell brottsprevention med den filosofin att skadegörelse, våld och stölder leder till otrygghet, vilket i sin tur leder till att människor inte vågar ta plats i det offentliga rummet. Konsekvensen blir att de offentliga platserna mister sin sociala kontroll, och kriminalitet och otryggheten får ytterligare spelrum. ”Trygghet” förespråkar istället skapandet av en levande stad där folk vågar ta plats och på så sätt utöva en social och informell övervakning. I detta arbete undersöker jag hur tryggheten fungerar och hur den kan ökas i en otrygg park i södra Malmö -Kroksbäcksparken,

  • 1867. Aanes, R
    et al.
    Sæther, B-E
    Smith, F M
    Cooper, E J
    Wookey, Philip
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Earth Sciences, Department of Earth Sciences. Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Earth Sciences, Department of Earth Sciences, Environment and Landscape Dynamics. Miljö- och landskapsdynamik.
    The Arctic Oscillation predicts effects of climate change in the arctic ecosystem2002In: Ecology Letters, Vol. 4, p. 445-453Article in journal (Refereed)
  • 1868.
    Aanes R, Sæther B-E, Smith FM, Cooper EJ, Wookey PA, Øritsland NA
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Earth Sciences, Department of Earth Sciences. ENVIRONMENT AND LANDSCAPE DYNAMICS.
    The Arctic Oscillation predicts effects of climate change in two trophic levels in a high-arctic ecosystem2002In: Ecology Letters, ISSN ISSN 1461-023X, Vol. 5, p. 445-453Article in journal (Refereed)
    Abstract [en]

    During recent decades there has been a change in the circulation of atmospheric pressure throughout the Northern Hemisphere. These variations are expressed in the recently described Arctic Oscillation (AO), which has shown an upward trend (associated with

  • 1869. Aanesen, Arthur
    et al.
    Westerbotn, Margareta
    Sophiahemmet University.
    Prospective study of a Swedish infertile cohort 2005-08: population characteristics, treatments and pregnancy rates2014In: Family Practice, ISSN 0263-2136, E-ISSN 1460-2229, Vol. 31, no 3, p. 290-7Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: We here report on results from a prospective study comprising 380 infertile couples undergoing infertility work-up and various treatments for infertility in our clinic. The aim was to investigate the overall birth rate as a result of different treatments, as well as spontaneous pregnancies.

    METHODS: Three hundred and eighty couples were consecutively included between December 2005 and May 2008. All couples underwent a fertility work-up, including hysterosalpingogram, hormonal characterization, clinical examination, screening for infectious diseases and semen analysis. The mean age of the women at the time of inclusion was 33.2 years. The mean duration of infertility prior to inclusion was 1.8 years. And 46.6% (n = 177) of the women had been pregnant prior to their first visit to the clinic and 30.0% (n = 114) had been pregnant earlier in their present relationship.

    RESULTS: As of November 2010, 57.3% (n = 218) of the women had given birth to a child when they were lost to follow up by the study. Spontaneous conception was observed in 11.3% (n = 43) of the women, 14.5% (n = 64) conceived after intrauterine insemination (IUI), 4.2% (n = 16) conceived after ovarian hyperstimulation and ovulation induction (OH/OI) and 28.4% (n = 113) after in vitro fertilization. There were 280 pregnancies and 58 spontaneous abortions (22.3%) in the group. Mean anti-mullerian hormone significantly correlated with antral follicle count and age and was significantly higher in the subgroup that became pregnant after IUI.

    CONCLUSIONS: Spontaneous pregnancies and IUI + OH/OI contributed significantly to the pregnancies observed in the total population. Predictive factors for pregnancy were anti-mullerian hormone in the group undergoing IUI treatment and in the age group ≥38-duration of infertility. Previous pregnancies, body mass index, estradiol, follicle stimulating hormone or having given birth prior to the infertility period were not predictive of pregnancy for the infertile couples in this study.

  • 1870.
    Aanestad, O
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Surgical Sciences.
    Flink, R
    Department of Neuroscience.
    Urinary stress incontinence. A urodynamic and quantitative electromyographic study of the perineal muscles.1999In: Acta Obstet. Gynecol. Scand., Vol. 78, p. 245-Article in journal (Refereed)
  • 1871.
    Aanestad, Ö
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Neuroscience.
    Flink, R
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Neuroscience.
    Urinary stress incontinence: a urodynamic and quantitative electromyogrpahic study of the perineal muscles.1998In: Acta Obstet. Gynecol. Scand., Vol. 77, p. 1-Article in journal (Refereed)
  • 1872. Aanestad, Ö
    et al.
    Flink, R
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Neuroscience.
    Haggman, M
    Department of Surgical Sciences.
    Norlen, BJ
    Department of Surgical Sciences.
    Interference pattern in the urethral sphincter: a quantitative study in patients before and after radical retropubic prostatectomy.1998In: Scand J Urol and Nephrology, Vol. 32, p. 1-Article in journal (Refereed)
  • 1873.
    Aanestad, Öystein
    et al.
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Surgical Sciences.
    Flink, Roland
    Norlen, Bo Johan
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Surgical Sciences.
    Interference pattern in perineal muscles: A quantitative electromyographic study in patients before and after transurethral surgery of the prostate.1997In: Neurourol Urodyn, Vol. 16, p. 101-Article in journal (Refereed)
  • 1874.
    Aanestad, Øystein
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Surgical Sciences.
    Quantitative electromyographic studies of the perineal muscles in normal subjects and patients suffering from anal or urinary incontinence1998Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    The aims of the study were to characterize the interference pattern in perineal muscles in healthy subjects with the use of quantitative EMG techniques, to evaluate if prostatic surgery had any effect on the interference pattern and furthermore to examine the interference pattern in the perineal muscles in patients suffering from urinary or anal incontinence.

    The interference pattern in the perineal muscles was examined with a computerized analysis, the Turns and Amplitude (T/A) analysis, and the innervation pattern of the muscles was examined with single fiber electromyography measuring the fiber density. Reference values were collected from 30 normal subjects. The patient material consisted of 20 males subjected to transurethral prostatectomy (TUR-P), 10 males who underwent radical retropubic prostatectomy (RRP), 20 patients suffering from anal incontinence and 24 women withurinary incontinence.

    T/A analysis of the interference pattern in the perineal muscles in normal subjects showed a significant increase in number of turns/sec and mean amplitude correlating to increasing force but no age-related changes.

    TUR-P and RRP did effect the innervation of the distal urethral sphincter muscle as shown by increased fiber density indicating a peripheral nerve lesion. T/A analysis did not shown any increased activation of the distal urethral sphincter as a compensation for the loss in bladder neck sphincter function but rather signs of decreasedcentral activation.

    Patients with idiopathic faecal incontinence showed signs of impaired innervation of the external anal sphincter muscle. A decreased interference pattern at maximal contraction indicated a reduced central activation of perineal muscles, in particular for patients with partial rupture of the external anal sphincter muscle. The reduced central activation could play a role for the aetiology of faecal incontinence.

    Patients with urinary stress incontinence also showed signs of impaired innervation of the external anal sphincter muscle as well as reduced interference pattern at maximal contraction and during continuous recording of the EMG activity during cystometry. A reduced central activation of the motor units was predicted as one factor involved in the aetiology.

  • 1875. Aannestad, Hanne Lovise
    Gjenstander over grenser: potensialet i studier av importerte og ikke-lokale gjenstander i vikingtid2016In: Fornvännen, ISSN 0015-7813, E-ISSN 1404-9430, Vol. 111, no 4, p. 217-228Article in journal (Other academic)
  • 1876. Aanstad, Siri
    et al.
    Koch, Per
    Foreign takeovers in the Nordic countries (FOTON)2005Book (Other (popular science, discussion, etc.))
    Abstract [en]

    Like domestic owned multinational companies, foreign owned multinational companies represent equally positive opportunities for Nordic trade and industry, both in terms of innovative capabilities and value creation. There are no apparent reasons for leading a different policy towards companies with foreign ownership. The governments in the Nordic countries should encourage initiatives that attract this type of companies. Foreign owned multinationals take part in international networks that might benefit other firms in the national innovation system.

  • 1877. Aapro, Matti
    et al.
    Beguin, Yves
    Birgegård, Gunnar
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Gascon, Pere
    Hedenus, Michael
    Österborg, Anders
    Too-Low Iron Doses and Too Many Dropouts in Negative Iron Trial?2011In: Journal of Clinical Oncology, ISSN 0732-183X, E-ISSN 1527-7755, Vol. 29, no 17, p. E525-E526Article in journal (Refereed)
  • 1878. Aapro, Matti S.
    et al.
    Birgegård, Gunnar
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
    Bokemeyer, Carsten
    Cornes, Paul
    Foubert, Jan
    Gascon, Pere
    Glaspy, John
    Hellström-Lindberg, Eva
    Link, Hartmut
    Ludwig, Heinz
    Österborg, Anders
    Repetto, Lazzaro
    Soubeyran, Pierre
    Erythropoietins should be used according to guidelines2008In: The Lancet Oncology, ISSN 1470-2045, E-ISSN 1474-5488, Vol. 9, no 5, p. 412-3Article in journal (Refereed)
  • 1879. Aarabi, Narjes
    et al.
    Bromideh, Ali Akbar
    The impact of e-commerce on the Iranian insurance companies2006Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    The conditions for doing business are rapidly changing. The Internet and related advances in information technology significantly affect financial services in general and insurance markets and institutions in particular. The growing importance of e-commerce represents a watershed event for insurance markets and institutions, as it does for most industries. By lowering information costs, e-commerce will enable insurers to classify, underwrite, and price risk as well as settle claims more accurately and efficiently. Overall, the Internet will significantly enhance the efficiency of insurance markets and institutions and benefit consumers by lowering transaction and information costs. The effects of e-commerce are the subjects of intense debate in insurance industry. The foundation for the purpose of this research has been created by a prospective study to explore the impact of application of e-commerce on the Iranian insurance industry. In order to fulfill the purpose of this study, a frame of reference has been emerged based on a vast literature review. With the focus at quantitative research as a general approach and descriptive research as the type of research in this study, a structured questionnaire was used as the data collection instrument. To accomplish this, a survey of 258 people (in almost all active insurance companies in Iran) has been carried out. The respondents from almost every department within the targeted insurance companies were randomly chosen. We have focused on the perception of insurers regarding the subject of study, and thus, the perception of other stakeholder such as insurance agents/brokers and even their customers have been suggested for future research, due to limitation and demarcation of this research. This dissertation has been organized in the seven chapters. An introduction this study, problem statements and research questions were presented in chapter one. The second chapter was devoted to literature review. The emerged frame of reference was provided in the third chapter and our research methodology was discussed in the fourth chapter. Data presentation and analysis were done in accordance with the research questions and the frame of reference in chapter five and six, respectively. Finally, in the last chapter findings and conclusions were drawn by answering the research questions. With respect to the findings, we conclude that the Iranian insurance companies were positively looked at e-commerce and its application in their companies. Their attitude and views toward e-commerce was positive so that they found that e-commerce would be an opportunity rather than a challenge or even a threat for insurance industry. They highly believed that e- commerce would affect on insurance companies and, thus, their companies should embrace e-commerce. Lack of skilled staffs in e-commerce application and scarcity of IT experts were the most infrastructure requirements which they found that the Iranian insures were suffering from. Whereas they were well equipped with hardware and networking as well as general and professional insurance software required in e-commerce applications. Lagging of other supportive sectors (e.g., e-Banking and Telecommunications), lack of appropriate legislation and regulation (e.g., copy right, digital signature, …), low Internet usage and fewer users, traditionally attitudes and views over the companies and scarcity of skilled staffs were the five top major obstacles which would hinder the Iranian insurers to embrace e-commerce. E-commerce is potentially applicable to marketing and sales as well as R&D with respect to insurance value chain. On the other hand, as far as insurance products concern, auto (motor) insurance, marine and aviation, life insurance and fire insurance were highly perceived to suitable to e- commerce (sale online). Finally, the Iranian insurance companies were chiefly believed that in the case of e-commerce application they would get these top five benefits: brand and image promotion (as a pioneer and modern company), extended corporation with partners (specially in the reinsurance cases), lower invest for establishing the sales and after sales services network, cost reduction in value chain management (e.g. product/service development) and decentralization and no restrictions imposed by national borders.

  • 1880.
    Aarao, J
    et al.
    University of South Australia.
    Bradshaw-Hajek, B H
    University of South Australia.
    Miklavcic, Stan
    Linköping University, Department of Science and Technology. Linköping University, The Institute of Technology.
    Ward, D A
    University of South Australia.
    Numerical implementation of the EDEM for modified Helmholtz BVPs on annular domains2011In: JOURNAL OF COMPUTATIONAL AND APPLIED MATHEMATICS, ISSN 0377-0427, Vol. 235, no 5, p. 1342-1353Article in journal (Refereed)
    Abstract [en]

    In a recent paper by the current authors a new methodology called the Extended-Domain-Eigenfunction-Method (EDEM) was proposed for solving elliptic boundary value problems on annular-like domains. In this paper we present and investigate one possible numerical algorithm to implement the EDEM. This algorithm is used to solve modified Helmholtz BVPs on annular-like domains. Two examples of annular-like domains are studied. The results and performance are compared with those of the well-known boundary element method (BEM). The high accuracy of the EDEM solutions and the superior efficiency of the EDEM over the BEM, make EDEM an excellent alternate candidate to use in the animation industry, where speed is a predominant requirement, and by the scientific community where accuracy is the paramount objective.

  • 1881.
    Aarao, J
    et al.
    University of South Australia.
    Bradshaw-Hajek, B H
    University of South Australia.
    Miklavcic, Stan
    Linköping University, Department of Science and Technology. Linköping University, The Institute of Technology.
    Ward, D A
    University of South Australia.
    The extended-domain-eigenfunction method for solving elliptic boundary value problems with annular domains2010In: JOURNAL OF PHYSICS A-MATHEMATICAL AND THEORETICAL, ISSN 1751-8113, Vol. 43, no 18, p. 185202-Article in journal (Refereed)
    Abstract [en]

    Standard analytical solutions to elliptic boundary value problems on asymmetric domains are rarely, if ever, obtainable. In this paper, we propose a solution technique wherein we embed the original domain into one with simple boundaries where the classical eigenfunction solution approach can be used. The solution in the larger domain, when restricted to the original domain, is then the solution of the original boundary value problem. We call this the extended-domain-eigenfunction method. To illustrate the methods strength and scope, we apply it to Laplaces equation on an annular-like domain.

  • 1882.
    Aarao, J
    et al.
    University of S Australia, Australia .
    Miklavcic, Stan J.
    Linköping University, Department of Science and Technology. Linköping University, The Institute of Technology.
    Ward, D A.
    University of S Australia, Australia .
    Extended-domain-eigenfunction method (EDEM): a study of ill posedness and regularization2013In: Journal of Physics A: Mathematical and Theoretical, ISSN 1751-8113, E-ISSN 1751-8121, Vol. 46, no 8Article in journal (Refereed)
    Abstract [en]

    The extended-domain-eigenfunction method (EDEM) proposed for solving elliptic boundary value problems on annular-like domains requires an inversion process. The procedure thus represents an ill-posed problem, whose numerical solution involves an ill-conditioned system of equations. In this paper, the ill-posed nature of EDEM is studied and numerical solutions based on regularization schemes are considered. It is shown that the EDEM solution methodology lends itself naturally to a formulation in terms of the well-known iterative Landweber method and the more general and faster converging semi-iterative regularization schemes. Theoretical details and numerical results of the regularization schemes are presented for the case of the two-dimensional Laplace operator on annular domains.

  • 1883.
    Aardal, Elisabeth
    et al.
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Faculty of Health Sciences.
    Ann-Charlotté, Holm
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Faculty of Health Sciences.
    Cortisol in Saliva: Reference Ranges and Relation to Cortisol in Serum1995In: European Journal of Clinical Chemistry and Clinical Biochemistry, ISSN 0939-4974, Vol. 33, p. 927-932Article in journal (Refereed)
    Abstract [en]

    The aim of this study was to establish morning and evening reference ranges for cortisol in saliva. Another objective was to compare the concentrations of the mainly free cortisol in saliva to those of total cortisol in serum as determined with a commercial radioimmunoassay. The concentrations were determined in matched samples of saliva and serum collected at 8am and 10pm from 197 healthy volunteers. The saliva samples were stable for at least 7 days at room temperature and for 9 months at —20 °C. Reference ranges, the central 95%, were estimated to 3.5—27.0 nmol/1 at 8 am and < 6.0 nmol/1 at 10 pm. The intra-assay coefficient of variation (CV) was below 5% and total CV below 10%. The relation between the cortisol concentrations in serum and saliva was nonlinear with r = 0.86 for serum concentrations < 450 nmol/1 and r = 0.44 for serum concentrations ^ 450 nmol/1. In conclusion, the satisfactory precision of the analysis and the simple non-invasive sampling procedure suggest that saliva may be used for cortisol measurements in situations where blood sampling is difficult to perform.

  • 1884.
    Aardal, Karen
    et al.
    Department of Mathematics, Linköping Institute of Technology.
    Ari, Aysen
    Luleå tekniska universitet.
    Decomposition principles applied to the dynamic production and work-force scheduling problem1987In: Engineering Costs and Production Economics, ISSN 0167-188X, E-ISSN 1878-4011, Vol. 12, no 1-4, p. 39-49Article in journal (Refereed)
    Abstract [en]

    One of the most important problems in the production and inventory planning field, is the scheduling of production and work force in a dynamic environment. Although this problem can be formulated as a linear program, it is often quite difficult to solve directly, due to its large scale. Instead, it might be fruitful to use a decomposition approach. Decomposition, in general, means decomposing a difficult problem into several easier, or a sequence of easier problems which are later coordinated to reconstruct the original problem.In this report we discuss several possibilities of applying the most common decomposition principles, namely Benders (primal) and Datnzig-Wolfe (dual), as well as a relatively new decomposition method, called cross decomposition, to the dynamic, multiproduct production and employment planning problem. A number of special cases are also presented.

  • 1885.
    Aardal, Karen
    et al.
    CORE, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
    Ari, Aysen
    Luleå tekniska universitet.
    On the resemblance between the Kornai-Liptak and cross decomposition techniques for block-angular linear programs1990In: European Journal of Operational Research, ISSN 0377-2217, E-ISSN 1872-6860, Vol. 46, no 3, p. 393-398Article in journal (Refereed)
    Abstract [en]

    In this paper the resemblance is demonstrated between the master- and subproblems generated by the Kornai-Liptak algorithm and the subproblems obtained by using the cross decomposition method on linear optimization problems with block-angular structure. The significance of the similarity between these two algorithms becomes apparent considering the main disadvantage attributed to cross decomposition. In cross decomposition a master problem has to be solved from time to time since the subproblems alone do not always give a converging sequence of primal and dual solutions. But if the cross decomposition algorithm is modified in such a way that the successive primal and dual subproblem solutions are taken into consideration with equal weights, this results in the Kornai-Liptak algorithm for which convergence is guaranteed

  • 1886. Aardal, S
    et al.
    Aardal, NP
    Larsen, TH
    Angeletti, RH
    Stridsberg, M
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences.
    Taupenot, L
    Aunis, D
    Helle, KB
    Human pheochromocytoma: different patterns of catecholamine and chromogranins in the intact tumour, urine and serum in clinically unsuspected cases1996In: Scand J clin Lab Invest, Vol. 56, p. 511-Article in journal (Refereed)
  • 1887. Aardal-Eriksson, E
    et al.
    Eriksson, T.E
    Holm, A-C
    Lundin, T
    Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Neuroscience.
    Salivary cortisol and serum prolactin in relation to stress rating scales in a group of rescue workers1999In: Biol. Psychiatry, Vol. 46, p. 850-Article in journal (Refereed)
  • 1888.
    Aardal-Eriksson, Elisabeth
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Department of Neuroscience and Locomotion, Psychiatry. Linköping University, Faculty of Health Sciences.
    Salivary cortisol and posttraumatic stress reactions: methodological and applied studies before and after trauma2002Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    The field of psychotraumatology has its roots in ancient history. During the past decades, the surveillance of the psychobiological background of reactions to and consequences of traumatic stress has made great progress and the complexity of the human stress response system stands out. The hypothalamic-pituitary-adrenocortical axis activity, modulated by various neuroimmunological substances, seems to play a major role in the stress response. However, there are still inconsistencies in explanations of relationships between biological and psychological changes following traumatic stress. Moreover, the matter of predictive factors for the development of posttraumatic morbidity is still in a speculative phase.

    The aims of the present thesis were to further develop a commercial serum cortisol radioimmunoassay (RIA) for determination of cortisol in saliva and to test its reliability, specificity and sensitivity as a biochemical assay. The saliva sampling procedures and sample storage stability were also to be tested. Further issues were to investigate determinations of salivary cortisol and serum prolactin in relation to selfratings of posttraumatic psychological distress and general psychological health. Possible predictive and concurrent validity of salivary cortisol as a biochemical marker for posttraumatic psychological distress were to be tested.

    Cortisol is present in saliva mainly in non-protein form, representing the free, biologically active fraction of the total plasma cortisol concentration. In a first phase of the present thesis, the commercial serum cortisol RIA was modified for determination of cortisol in saliva. The relation between salivary and serum cortisol concentrations was tested. Reference ranges at 8 AM and 10 PM for the salivary cortisol assay were established from 195 healthy subjects. Salivary cortisol concentrations were tested in relation to serum cortisol in estimating adrenocortical function during endocrine dynamic function tests in 37 patients and 13 healthy controls. In testing salivary cortisol as a marker for stress for fieldwork use, a screening study was performed on 66 male rescue workers. Salivary cortisol at 8 AM and 10 PM and serum prolactin were determined and general psychological health and posttraumatic psychological distress were estimated with the self-rating scales General Health Questionnaire, Impact of Event Scale and Posttraumatic Symptom Scale. These scales were used in the second phase of the thesis. Three applied follow-up studies were performed with sampling of salivary cortisol and self-ratings: (a) a study of 31 UN-soldiers five days, two and nine months after a mine accident; (b) a study of 145 UN-soldiers before, at return, and two and six month after a six month mission. (c) a study of 101 UN-soldiers six and twelve months after a six month mission with severe combat exposure.

    The results from the present thesis indicate that the modified method of salivary cortisol determination possesses sufficient precision, accuracy, sample storage stability and procedural advantages for laboratory, clinical and field application. Moreover, it possesses moderate predictive information and moderate to high concurrent validity as a biochemical marker for posttraumatic psychological distress.

  • 1889.
    Aardal-Eriksson, Elisabeth
    et al.
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Faculty of Health Sciences.
    Eriksson, Thomas E.
    Linköping University, Department of Neuroscience and Locomotion, Psychiatry. Linköping University, Faculty of Health Sciences.
    Thorell, Lars-Håkan
    Linköping University, Department of Neuroscience and Locomotion, Psychiatry. Linköping University, Faculty of Health Sciences.
    Pre-trauma Salivary Cortisol Levels and General Health Ratings in Relation to Post-trauma Changes in Cortisol and Psychological Distress after UN-service in BosniaManuscript (preprint) (Other academic)
    Abstract [en]

    Background: The psychobiology of post-traumatic distress is known to some extent, however the pre-trauma psychobiology is not. The aims of the present study were to relate pre- and post-trauma salivary cortisol levels and general health to post-traumatic distress in a Swedish UN-battalion in Bosnia.

    Methods: Salivary 8 AM and I 0 PM cortisol levels and "General Health Questionnaire" ratings were collected from 145 subjects before the six months' mission, at return and two and six months after mission. During follow-up, the ratings were extended by the "Impact of Events Scale" (IES) and "Post Traumatic Symptom Scale".

    Results: Low pre-trauma morning and evening salivary cortisol levels were statistically significantly related to high scores in all rating scales six months after mission and to increasing IES scores during follow-up. Low morning and high evening post-trauma salivary cortisol levels were related to high ratings of psychological distress six months after mission

    Conclusions: Pre-trauma salivary cortisol levels seem to be related to posttrauma psychological distress, however not to the extent that salivary cortisol levels in a simple way could be used for predictive screening.

  • 1890.
    Aardal-Eriksson, Elisabeth
    et al.
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Faculty of Health Sciences.
    Eriksson, Thomas E.
    Linköping University, Department of Neuroscience and Locomotion, Psychiatry. Linköping University, Faculty of Health Sciences.
    Thorell, Lars-Håkan
    Linköping University, Department of Neuroscience and Locomotion, Psychiatry. Linköping University, Faculty of Health Sciences.
    Salivary cortisol, posttraumatic stress symptoms, and general health in the acute phase and during 9-month follow-up2001In: Biological Psychiatry, ISSN 0006-3223, E-ISSN 1873-2402, Vol. 50, no 12, p. 986-993Article in journal (Refereed)
    Abstract [en]

    Background: Because traumatic events are unpredictable, there are few studies of psychobiological states immediately following such events. Our study aimed to determine the relation of salivary cortisol to psychologic distress immediately after a traumatic event and then during follow-up.

    Methods: Measurement of morning and evening salivary cortisol and ratings of psychologic distress (using the Impact of Events Scale [IES], the Post Traumatic Symptom Scale, and the General Health Questionnaire) were performed with 31 United Nations soldiers at three time points—5 days and 2 and 9 months—following a mine accident in Lebanon.

    Results: Five days after the accident, 15 subjects reported substantial posttraumatic distress according to the IES, as well as significantly lower morning and higher evening cortisol levels compared with the low-impact group. Within 9 months, the posttraumatic distress of the high-impact group was reduced, accompanied by an increase in morning and a decrease in evening cortisol levels. There were significant relationships between evening cortisol and all rating scales at the first and third time points.

    Conclusions: Subclinical posttraumatic stress following an adverse event can be measured biologically via salivary cortisol levels soon after the event.

  • 1891.
    Aardal-Eriksson, Elisabeth
    et al.
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Faculty of Health Sciences.
    Eriksson, Thomas E.
    Linköping University, Department of Neuroscience and Locomotion, Psychiatry. Linköping University, Faculty of Health Sciences.
    Thorell, Lars-Håkan
    Linköping University, Department of Neuroscience and Locomotion, Psychiatry. Linköping University, Faculty of Health Sciences.
    Twelve Months Follow-up of Salivary Cortisol in Relation to Psychological Distress and General Health in Swedish UN-personnel after Severe Combat Exposure during Six Months Mission in BosniaManuscript (preprint) (Other academic)
    Abstract [en]

    Background: Our group has presented evidence of relationships between salivary cortisol levels and psychological distress before, during and after trauma-related stress. The aim of the present study was to confirm the part of evidence of relationships between salivary cortisol and posttraumatic distress and their change over time.

    Methods: Salivary cortisol levels at 8 AM and 10 PM and self-ratings were collected from 106 subjects six and twelve months after a six months UNmission in Bosnia. The rating instruments were the "Impact of Event Scale" (IES), the "Post Traumatic Symptom Scale" and the "General Health Questionnaire".

    Results: Significant statistical interactions were found between changes in mean cortisol levels and IES scores over time. Decreasing evening cortisol levels over time were significantly related to decreasing IES scores and vice versa. Morning cortisol levels showed negative, and evening cortisol positive correlations with all rating scores.

    Conclusions: The evidence from previous studies on trauma related stress, that salivary cortisol is related to the development of posttraumatic stress reactions, the morning cortisol in reverse (negative) direction to that (positive) of evening cortisol, were confirmed.

  • 1892.
    Aardal-Eriksson, Elisabeth
    et al.
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Faculty of Health Sciences.
    Eriksson, Thomas
    Linköping University, Department of Neuroscience and Locomotion, Psychiatry. Linköping University, Faculty of Health Sciences.
    Holm, Ann-Charlotte
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Faculty of Health Sciences.
    Lundin, Tom
    Department of Psychiatry, Uppsala Academic Hospital, Uppsala University, Uppsala (TL), Sweden.
    Salivary cortisol and serum prolactin in relation to stress rating scales in a group of rescue workers1999In: Biological Psychiatry, ISSN 0006-3223, E-ISSN 1873-2402, Vol. 46, no 6, p. 850-855Article in journal (Refereed)
    Abstract [en]

    Background: Rescue service personnel are often exposed to traumatic events as part of their occupation, and higher prevalence rates of psychiatric illness have been found among this group.

    Methods: In 65 rescue workers, salivary cortisol at 8 am and 10 pm and serum prolactin at 8 am were related to the psychiatric self-rating scale General Health Questionnaire (GHQ-28) measuring psychiatric health, and the Impact of Events Scale (IES) and Post Traumatic Symptom Scale (PTSS) measuring posttraumatic symptoms.

    Results: Seventeen percent of the study population scored above the GHQ-28 cut-off limit but none scored beyond the cut-off limit in the IES and PTSS questionnaires. Salivary cortisol concentration at 10 pm correlated with statistical significance to anxiety (p < .005) and depressive symptoms (p < .01) measured with GHQ-28, as well as to posttraumatic symptoms, with avoidance behavior measured with IES (p < .01) and PTSS (p < .005). Two of the rescue workers were followed over time with the same sampling procedure after a major rescue commission.

    Conclusions: The correlation between evening salivary cortisol and anxiety, depressiveness, and posttraumatic avoidance symptoms indicates that these parameters can be used in screening and follow-up after traumatic stress events.

  • 1893.
    Aardal-Eriksson, Elisabeth
    et al.
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Neuroscience and Locomotion.
    Holm, AC
    Eriksson, TE
    Lundin, T
    Linkoping Univ, Fac Hlth Sci, Dept Biomed & Surg, Ctr Clin Chem, S-58185 Linkoping, Sweden.
    Thorell, Lars-Håkan
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Clinical and Experimental Medicine, Psychiatry . Östergötlands Läns Landsting, Local Health Care Services in Central Östergötland, Department of Psychiatry.
    Salivary cortisol and posttraumatic stress reactions methodological and applied studies before and after trauma2002In: International Journal of Psychophysiology, ISSN 0167-8760, E-ISSN 1872-7697, Vol. 45, no 1-2, p. 89-89Conference paper (Other academic)
  • 1894.
    Aardal-Eriksson, Elisabeth
    et al.
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Faculty of Health Sciences.
    Karlberg, Bengt E.
    Linköping University, Department of Medicine and Care, Internal Medicine. Linköping University, Faculty of Health Sciences.
    Holm, Ann-Charlotte
    Linköping University, Department of Biomedicine and Surgery, Clinical Chemistry. Linköping University, Faculty of Health Sciences.
    Salivary cortisol: an alternative to serum cortisol determinations in dynamic function tests1998In: Clinical Chemistry and Laboratory Medicine, ISSN 1434-6621, E-ISSN 1437-4331, Vol. 36, no 4, p. 215-222Article in journal (Refereed)
    Abstract [en]

    Salivary cortisol was measured as an alternative to serum cortisol as a marker for adrenocortical function following insulin tolerance test, corticotropin-releasing-hormone stimulation and adreno-corticotrophic hormone stimulation. During insulin tolerance test and corticotropin-releasing-hormone stimulation adreno-corticotrophic hormone was also measured. The tests were performed on healthy control subjects as well as on patients under investigation for various disturbances in the hypothalamic-pituitary-adrenocortical axis (insulin tolerance test: 3 controls on two occasions and 14 patients; corticotropin-releasing-hormone stimulation: 4 controls and 18 patients; adreno-corticotrophic hormone stimulation: 6 controls and 10 patients). Five patients underwent both insulin tolerance test and corticotropin-releasing-hormone stimulation. Using criteria for adequate cortisol response in serum, the patients were classified as good or poor responders. In 42 of the 45 tests performed the same conclusion as to cortisol status was drawn when based on serum and salivary cortisol responses. In healthy subjects and good responders the mean cortisol relative increase was greater in saliva than in serum in all three tests (p < 0.05). Characteristic of the results for the insulin tolerance test was a significant initial mean decrease (p < 0.05), not found in serum, and the highest observed salivary cortisol value was delayed for at least 30 minutes compared to that in serum. Plasma adreno-corticotrophic hormone correlated significantly with the cortisol concentrations determined 15 minutes later in serum (r = 0.54–0.64) and in saliva (r = 0.76–0.85). The more pronounced cortisol response in saliva than in serum and its closer correlation with adreno-corticotrophic hormone offer advantages over serum cortisol, suggesting salivary cortisol measurement may be used as an alternative parameter in dynamic endocrine tets.

  • 1895.
    Aardal-Eriksson, Elisabeth
    et al.
    Linköping University, Department of Clinical and Experimental Medicine, Division of Microbiology and Molecular Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Diagnostics, Department of Clinical Chemistry.
    Mobäck, Caroline
    Region Östergötland, Center for Diagnostics, Department of Clinical Chemistry.
    Jakobsson, Sandra
    Region Östergötland, Center for Diagnostics, Department of Clinical Chemistry. Germany.
    Hoffmann, Johannes J. M. L.
    Abbott GmbH and Co KG, Germany.
    Iron depletion in blood donors - Have extended erythrocyte and reticulocyte parameters diagnostic utility?2015In: Transfusion and apheresis science, ISSN 1473-0502, E-ISSN 1878-1683, Vol. 53, no 1, p. 76-81Article in journal (Refereed)
    Abstract [en]

    Background: Blood donation is associated with iron depletion, but donor iron status is not usually investigated, as such tests are cumbersome and costly. It would therefore be desirable to have simple, fast and inexpensive tests that give information on a donors risk of developing iron depletion. In a pilot study we investigated whether novel erythrocyte and reticulocyte parameters can serve this goal. Methods: In regular blood donors extended red cell parameters were measured using the Abbott CELL-DYN Sapphire hematology analyzer and conventional biochemical tests of iron status. Donors were compared with a regionally matched group of non-donating controls. Results: In the controls, the reference ranges of extended RBC parameters were well comparable to published data. Donors had significantly more microcytic RBC than controls (median 0.9 vs 0.6%), lower serum ferritin concentration (median 43 vs 91 mg/L) and higher soluble transferrin receptor/ferritin index (median 1.60 vs 1.27). Overall 18-28% of the donors were iron depleted. Moreover, 3.3% of donors had iron-restricted erythropoiesis. Microcytic RBC and reticulocyte mean cell hemoglobin content predicted iron depletion with 70% and 64% sensitivities and specificities of 72% and 78%, respectively. When combined these two parameters increased the sensitivity to 82%. Conclusions: Our results in Swedish blood donors confirm a high prevalence of iron depletion, despite iron supplementation used by about half of the donors. Microcytic RBC and MCHr appeared to be helpful in identifying iron-depleted donors, who might benefit from iron supplementation. We recommend larger prospective investigations in order to confirm and extend the findings of this pilot study. (C) 2015 Elsevier Ltd. All rights reserved.

  • 1896.
    Aardeck, Anna-Katharina
    et al.
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Business Administration.
    Behling, Corinna
    Umeå University, Faculty of Social Sciences, Umeå School of Business and Economics (USBE), Business Administration.
    Customer Value's Influence on International Market Entry Strategies in a B2B Context: Business and Market Opportunities in the Data Centre Segment in Northern Europe2016Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    nternational market entry strategies gained increasing importance due to globalisation. Companies became multinationals. Therefore, new challenges arose due to different market and customer requirements. One topic, which gained importance in B2B context, is customer value. Customer value can be defined as the perceived benefits a company delivers its customers in comparison to the perceived expenses. Nevertheless, no uniform definition exist. In addition to that, if there is a direct connection between B2B customer value and international market entry strategies have not been investigated yet. Therefore, this thesisprojectdeals with the influence of B2B customer value on international market entry strategies. To determine the link, following research question guides this thesis: How does B2B customer value influence international market entry strategies in Northern Europe?The research isnot only focused on Northern Europe but also on the data centre segment. The investigated countries are Norway, Ireland, UK and Finland. These countries are highly interesting for the commission partnerdue to market developments and mega trends. Furthermore, the commission partneris represented by local subsidiaries in the four countries of interest. In order to answer the research question, deep insights are generated via semi-structured interviews. Three customer groups are investigated: Data centre operator as well as owner, constructors including panel builder and system integrators as well as design consultants. The interviews are conducted either face-to-face or if necessary via telephone in the four countries of interest. The interviews include questions about B2B relationships, brand and marketing.If culture influences B2B customer value is investigated indirectly bythe questions on B2B relationship.Market intelligence questions are added in order to create a deeper understanding of the market.Furthermore, these insights also help to interpret the answers of customers. Due to the interviews, a picture of the B2B customer value in Northern Europe is created. Northern European customers value reliable suppliers who can offer quality products as well as solutions. In addition to that, the importance of global brands andmarketing of competences is determined. Due to combining the findings with the cultural dimensions of Hofstede, it is concluded that customer value differs between other countries.Hence, customer value influences international market strategies, as different customer value require distinct international market entry strategies.

  • 1897. Aardema, Frederick
    et al.
    Johansson, Petter
    Uppsala University, The Swedish Collegium for Advanced Study in the Social Sciences (SCASSS).
    Hall, Lars
    Paradisis, Stella-Marie
    Zidani, Melha
    Roberts, Sarah
    Choice Blindness, Confabulatory Introspection, and Obsessive-Compulsive Symptoms: A New Area of Investigation2014In: International Journal of Cognitive Therapy, ISSN 1937-1209, E-ISSN 1937-1217, Vol. 7, no 1, p. 83-102Article in journal (Refereed)
    Abstract [en]

    The current study is the first to investigate confabulatory introspection in relation to clinical psychological symptoms utilizing the Choice Blindness Paradigm (CBP). It was hypothesized that those with obsessive-compulsive symptoms are more likely to confabulate mental states. To test this hypothesis, an experimental choice blindness task was administered in two nonclinical samples (n = 47; n = 76). Results showed that a confabulatory introspection is significantly related to obsessive-compulsive symptoms. There was evidence for its specificity to symptoms of OCD depending on the obsessional theme addressed in the choice blindness task. However, confabulatory introspection was also found to be relevant to other symptoms, including depression and schizotypy. The results highlight a potentially fruitful new area of clinical investigation in the area of insight and self-knowledge, not limited to OCD alone, but potentially other disorders as well.

  • 1898.
    Aardoom, Leendert
    Uppsala University, Disciplinary Domain of Science and Technology.
    Some theoretical contributions to geodetic modeling of range-related observations in space1973Doctoral thesis, comprehensive summary (Other academic)
  • 1899.
    Aare, Anders
    Stockholm University of the Arts, The Film and Media Department.
    Ljuddesign för scenen2009Book (Other academic)
  • 1900.
    Aare, Cecilia
    Södertörn University, School of Social Sciences, Journalism.
    A Narratological Approach to Literary Journalism: How an Interplay between Voice and Point of View May Create Empathy with the Other2016In: Literary Journalism Studies, ISSN 1944-897X, E-ISSN 1944-8988, Vol. 8, no 1, p. 106-139Article in journal (Refereed)
    Abstract [en]

    The aim of this essay is to present a model for analyzing the in- terplay between voice and point of view in literary journalism/reportage. The model can be used to nuance previous researchers’ discussions about “subjective” and “objective” journalism. It also problematizes the reporter’s special role as an eyewitness by highlighting how narrative techniques can create empathy with the Other and move the reader’s gaze away from the reporter, away from the one who is witnessing. Using tools from classical narratology, I focus on the form of the texts. The tools help me investigate the narrator’s as well as the characters’ subjectivity and interpret the narra- tive’s construction as an expression of a journalistic mission. I systematize variables such as the narrator’s visibility, the relation between an experienc- ing reporter and a narrating reporter, the interplay between the experienc- ing reporter and other characters in the text, and in what way a level with a director (an implied author) can facilitate a comparison between vari- ous kinds of literary journalism. I also examine whether it might be time to abandon the theory that a first-person reportage is more subjective in general than a third-person reportage. I explore whether it is instead the narrator’s visibility that determines the position of the text on a scale be- tween “subjective” and “objective” forms. (Note: I have provided a glossary of terms at the end of the essay.)

35363738394041 1851 - 1900 of 1156728
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf