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  • 1551.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Institute, Stockholm, Sweden.
    Haapala, Irja
    McNeill, Geraldine
    Tseng, Marilyn
    Hodge, Allison
    The vulnerable child2011In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 14, no 10, p. 1701-1701Article in journal (Other academic)
  • 1552.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences and Nutrition, Novum, Huddinge, Sweden .
    Hambraeus, Leif
    Unit for Preventive Nutrition, Department of Biosciences and Nutrition, Novum, Huddinge, Sweden .
    Lissner, Lauren
    Department of Community Medicine and Public Health, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.
    Serra Majem, Lluis
    Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Spain; Sociedad Espanola de Nutricion Comunitaria (Spanish Society of Public Health Nutrition), Spain .
    Vaz de Almeida, Maria Daniel
    Faculty of Nutrition and Food Sciences, University of Porto, Portugal; Portuguese Society for Nutrition and Food Sciences, Porto, Portugal .
    Berg, Christina
    Department of Home Economics, Göteborg University, Göteborg, Sweden .
    Hughes, Roger
    School of Public Health (Gold Coast), Griffith University, QLD, Australia .
    Cannon, Geoffrey
    World Health Policy Forum Juiz de Fora, Minas Gerais, Brazil.
    Thorsdottir, Inga
    Unit for Nutrition Research, Landspitali-University Hospital, Iceland; University of Iceland, Reykjavik, Iceland .
    Kearney, John
    Department of Biological Sciences, Dublin Institute of Technology, Dublin, Ireland .
    Gustafsson, Jan-Åke
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden .
    Rafter, Joseph
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden .
    Elmadfa, Ibrahim
    Department of Nutritional Sciences, University of Vienna, Austria .
    Kennedy, Nick
    Department of Clinical Medicine, Trinity College, Dublin, Ireland .
    The Women's Health Initiative. What is on trial: nutrition and chronic disease? Or misinterpreted science, media havoc and the sound of silence from peers?2006In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 9, no 2, p. 269-272Article in journal (Refereed)
    Abstract [en]

    The first results of the Women's Health Initiative dietary intervention trial were published in the USA in February. This is a colossal intervention designed to see if diets lower in fat and higher in fruits, vegetables and grains than is usual in high-income countries reduce the incidence of breast cancer, colorectal cancer, heart disease and other chronic diseases, in women aged 50-79 years. As interpreted by US government media releases, the results were unimpressive. As interpreted by a global media blitz, the results indicate that food and nutrition has little or nothing to do with health and disease. But the trial was in key respects not reaching its aims, was methodologically controversial, and in any case has not produced the reported null results. What should the public health nutrition profession do about such messes?

  • 1553.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences and Nutrition, Novum, Huddinge, Sweden .
    Hambraeus, Leif
    Unit for Preventive Nutrition, Department of Biosciences and Nutrition, Novum, Huddinge, Sweden .
    Lissner, Lauren
    Department of Community Medicine and Public Health, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.
    Serra Majem, Lluis
    Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Spain; Sociedad Espanola de Nutricion Comunitaria (Spanish Society of Public Health Nutrition), Spain .
    Vaz de Almeida, Maria Daniel
    Faculty of Nutrition and Food Sciences, University of Porto, Portugal; Portuguese Society for Nutrition and Food Sciences, Porto, Portugal .
    Berg, Christina
    Department of Home Economics, Göteborg University, Göteborg, Sweden .
    Hughes, Roger
    School of Public Health (Gold Coast), Griffith University, QLD, Australia .
    Cannon, Geoffrey
    World Health Policy Forum Juiz de Fora, Minas Gerais, Brazil.
    Thorsdottir, Inga
    Unit for Nutrition Research, Landspitali-University Hospital, Iceland; University of Iceland, Reykjavik, Iceland .
    Kearney, John
    Department of Biological Sciences, Dublin Institute of Technology, Dublin, Ireland .
    Gustafsson, Jan-Åke
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden .
    Rafter, Joseph
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden .
    Elmadfa, Ibrahim
    Department of Nutritional Sciences, University of Vienna, Austria .
    Kennedy, Nick
    Department of Clinical Medicine, Trinity College, Dublin, Ireland .
    The Women's Health Initiative. What is on trial: nutrition and chronic disease? Or misinterpreted science, media havoc and the sound of silence from peers?2006In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 9, no 2, p. 269-272Article in journal (Refereed)
    Abstract [en]

    The first results of the Women's Health Initiative dietary intervention trial were published in the USA in February. This is a colossal intervention designed to see if diets lower in fat and higher in fruits, vegetables and grains than is usual in high-income countries reduce the incidence of breast cancer, colorectal cancer, heart disease and other chronic diseases, in women aged 50-79 years. As interpreted by US government media releases, the results were unimpressive. As interpreted by a global media blitz, the results indicate that food and nutrition has little or nothing to do with health and disease. But the trial was in key respects not reaching its aims, was methodologically controversial, and in any case has not produced the reported null results. What should the public health nutrition profession do about such messes?

  • 1554.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Institute, Stockholm, Sweden.
    Hodge, Allison
    Tseng, Marilyn
    Haapala, Irja
    McNeill, Geraldine
    Public health nutrition interventions can be simple and effective2011In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 14, no 8, p. 1321-1322Article in journal (Other academic)
  • 1555.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden.
    Kylberg, Elisabeth
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden.
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden.
    Breast-feeding in Europe - rationale and prevalence, challenges and possibilities for promotion2001In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 4, no 6A, p. 1353-1355Article in journal (Refereed)
    Abstract [en]

    The status reports and other information collected showed that interpretation of the data on breast-feeding prevalence and duration collected at national or regional level within European countries is difficult, since this information is not collected in every country or it is gathered under different criteria. However, there seem to be vast differences in prevalence of breast-fed children and breast-feeding duration between European countries and possibly within countries. There is a need to establish monitoring systems enabling comparability of data between countries. Assessing determinants for breast-feeding is required as well. There are a number of important consensus documents supporting breast-feeding action. These documents are related to either one or more of the following categories: health benefits of breast-feeding; recommendations regarding breast-feeding duration and exclusiveness; providing guidance on breast-feeding promotion. Current recommendation is exclusive breast-feeding for 6 months.

  • 1556.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden.
    Kylberg, Elisabeth
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden.
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden.
    Breast-feeding in Europe - rationale and prevalence, challenges and possibilities for promotion2001In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 4, no 6A, p. 1353-1355Article in journal (Refereed)
    Abstract [en]

    The status reports and other information collected showed that interpretation of the data on breast-feeding prevalence and duration collected at national or regional level within European countries is difficult, since this information is not collected in every country or it is gathered under different criteria. However, there seem to be vast differences in prevalence of breast-fed children and breast-feeding duration between European countries and possibly within countries. There is a need to establish monitoring systems enabling comparability of data between countries. Assessing determinants for breast-feeding is required as well. There are a number of important consensus documents supporting breast-feeding action. These documents are related to either one or more of the following categories: health benefits of breast-feeding; recommendations regarding breast-feeding duration and exclusiveness; providing guidance on breast-feeding promotion. Current recommendation is exclusive breast-feeding for 6 months.

  • 1557.
    Yngve, Agneta
    et al.
    Karolinska Inst, Stockholm, Sweden.
    Margetts, Barrie
    University of Southampton, United Kingdom.
    Building centres of excellence, and a new approach to food guides2009In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 12, no 5, p. 589-590Article in journal (Other academic)
  • 1558.
    Yngve, Agneta
    et al.
    Karolinska Inst, Stockholm, Sweden.
    Margetts, Barrie
    University of Southampton, United Kingdom.
    Building centres of excellence, and a new approach to food guides2009In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 12, no 5, p. 589-590Article in journal (Other academic)
  • 1559.
    Yngve, Agneta
    et al.
    Örebro universitet, Restaurang- och hotellhögskolan.
    Margetts, Barrie
    Hughes, Roger
    Tseng, Marilyn
    Editorial on the occasion of the International Congress of Nutrition. World hunger: A good fight or a losing cause?2009In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 12, no 10, p. 1685-1686Article in journal (Other academic)
  • 1560.
    Yngve, Agneta
    et al.
    Örebro University, School of Hospitality, Culinary Arts & Meal Science.
    Margetts, Barrie
    Hughes, Roger
    Tseng, Marilyn
    Editorial on the occasion of the International Congress of Nutrition. World hunger: A good fight or a losing cause?2009In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 12, no 10, p. 1685-1686Article in journal (Other academic)
  • 1561.
    Yngve, Agneta
    et al.
    Örebro University, School of Hospitality, Culinary Arts & Meal Science.
    Margetts, Barrie
    Hughes, Roger
    Tseng, Marilyn
    Food insecurity: not just about rural communities in Africa and Asia2009In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 12, no 11, p. 1971-1972Article in journal (Other academic)
  • 1562.
    Yngve, Agneta
    et al.
    Örebro University, School of Hospitality, Culinary Arts & Meal Science.
    Margetts, Barrie
    Hughes, Roger
    Tseng, Marilyn
    Public health: someone must have been doing something right!2009In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 12, no 12, p. 2253-2254Article in journal (Other academic)
  • 1563.
    Yngve, Agneta
    et al.
    Karolinska Inst, Dept Biosci Novum, Unit Prevent Nutr, Stockholm, Sweden.
    Margetts, Barrie
    Faculty of Medicine, University of Southampton, United Kingdom.
    Sachdev, H. P. S.
    Sitaram Bhartia Inst Sci & Res, New Delhi, India.
    Guidance on publishing results and how we operate evidence-based policy2008In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 11, no 7, p. 655-656Article in journal (Other academic)
  • 1564.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Inst, Stockholm, Sweden.
    Margetts, Barrie
    Tseng, Marilyn
    Hughes, Roger
    Cannon, Geoffrey
    Climate change: time to redefine our profession2010In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 13, no 3, p. 301-302Article in journal (Other academic)
  • 1565.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Inst, Stockholm, Sweden.
    Oshaug, Arne
    Margetts, Barrie
    Tseng, Marilyn
    Hughes, Roger
    Cannon, Geoffrey
    World Food Summits: what for, and what value?2010In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 13, no 2, p. 151-152Article in journal (Other academic)
  • 1566.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden .
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden; Department of Physical Education and Health, University of Örebro, Örebro, Sweden .
    Breastfeeding determinants and a suggested framework for action in Europe2001In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 4, no 2B, p. 729-39Article in journal (Refereed)
    Abstract [en]

    This is a background paper for the EURODIET initiative. A number of international initiatives and documents were identified, such as the Baby-Friendly Hospital Initiative, the International Code of Marketing of Breast Milk Substitutes and a number of consensus reports from professional groups, that propose ways forward for breastfeeding promotion. These point at a range of initiatives on different levels. The determinants for successful breastfeeding have to be identified. They can be categorised into five groups; socio-demographic, psycho-social, health care related, community- and policy attributes. A framework for future breastfeeding promoting efforts on European level is suggested, within which these determinants are considered. A common surveillance system needs to be built in Europe, where determinants of breastfeeding are included. There is also a need for a surveillance system which makes it possible to use the collected data on local level, not only on national and supranational level. Combined with a thorough review of the effectiveness of already existing breastfeeding promotion programmes, a co-ordinated EU-EFTA action plan on breastfeeding should be formulated and implemented within a few years. Urgent action could take place in parallel, especially targeting young, low-income, less educated mothers.

  • 1567.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden .
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden; Department of Physical Education and Health, University of Örebro, Örebro, Sweden .
    Breastfeeding determinants and a suggested framework for action in Europe2001In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 4, no 2B, p. 729-39Article in journal (Refereed)
    Abstract [en]

    This is a background paper for the EURODIET initiative. A number of international initiatives and documents were identified, such as the Baby-Friendly Hospital Initiative, the International Code of Marketing of Breast Milk Substitutes and a number of consensus reports from professional groups, that propose ways forward for breastfeeding promotion. These point at a range of initiatives on different levels. The determinants for successful breastfeeding have to be identified. They can be categorised into five groups; socio-demographic, psycho-social, health care related, community- and policy attributes. A framework for future breastfeeding promoting efforts on European level is suggested, within which these determinants are considered. A common surveillance system needs to be built in Europe, where determinants of breastfeeding are included. There is also a need for a surveillance system which makes it possible to use the collected data on local level, not only on national and supranational level. Combined with a thorough review of the effectiveness of already existing breastfeeding promotion programmes, a co-ordinated EU-EFTA action plan on breastfeeding should be formulated and implemented within a few years. Urgent action could take place in parallel, especially targeting young, low-income, less educated mothers.

  • 1568.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Stockholm, Sweden .
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Stockholm, Sweden .
    Breastfeeding in countries of the European Union and EFTA: current and proposed recommendations, rationale, prevalence, duration and trends2001In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 4, no 2B, p. 631-645Article in journal (Refereed)
    Abstract [en]

    Recommendations suggest exclusive breast feeding for at least the first 4 to 6 months after birth. Paradoxically, an overwhelming proportion of breast feeding (BF) data in Europe refers to all BF, i.e. not only exclusive but also partial BF (including formula, juices, water, sweetened water etc). This makes it difficult to estimate to what extent the recommendations are met. There is currently strong evidence for recommending exclusive breast feeding for at least 6 months. Exclusive BF has progressively gained scientific support. Prevention of infections, allergies and chronic diseases and a favourable cognitive development are highlighted in the recent scientific literature. Further long-term studies on the effects of BF on prevention of chronic disease in the adult are needed. Great differences exist in BF prevalence and duration both within and between European countries. Trends point towards higher prevalence and duration, with some exceptions. Young mothers breast feed less than older mothers; single and/or less educated mothers breast feed less than married mothers with more education. However, inefficient and unreliable monitoring systems prevail, and the data are scarce, not only on exclusive BF but also on demographic, socio-economic, psychosocial and medical determinants of BF patterns. National BF coordinators have not been appointed in many countries, and only every second country has promotion of BF incorporated into their national plan of action for nutrition.

    Conclusions: Efficient surveillance systems, comparable across Europe and using common definitions and methodology, need to be developed. These should include determinants of breast feeding. A European consensus conference should urgently be organised, in which strategies for successful promotion of exclusive BF should be particularly considered. There is now strong evidence for a recommendation to breast feed exclusively for about 6 months, which is more than the duration recommended previously.

  • 1569.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Stockholm, Sweden .
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Stockholm, Sweden .
    Breastfeeding in countries of the European Union and EFTA: current and proposed recommendations, rationale, prevalence, duration and trends2001In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 4, no 2B, p. 631-645Article in journal (Refereed)
    Abstract [en]

    Recommendations suggest exclusive breast feeding for at least the first 4 to 6 months after birth. Paradoxically, an overwhelming proportion of breast feeding (BF) data in Europe refers to all BF, i.e. not only exclusive but also partial BF (including formula, juices, water, sweetened water etc). This makes it difficult to estimate to what extent the recommendations are met. There is currently strong evidence for recommending exclusive breast feeding for at least 6 months. Exclusive BF has progressively gained scientific support. Prevention of infections, allergies and chronic diseases and a favourable cognitive development are highlighted in the recent scientific literature. Further long-term studies on the effects of BF on prevention of chronic disease in the adult are needed. Great differences exist in BF prevalence and duration both within and between European countries. Trends point towards higher prevalence and duration, with some exceptions. Young mothers breast feed less than older mothers; single and/or less educated mothers breast feed less than married mothers with more education. However, inefficient and unreliable monitoring systems prevail, and the data are scarce, not only on exclusive BF but also on demographic, socio-economic, psychosocial and medical determinants of BF patterns. National BF coordinators have not been appointed in many countries, and only every second country has promotion of BF incorporated into their national plan of action for nutrition.

    Conclusions: Efficient surveillance systems, comparable across Europe and using common definitions and methodology, need to be developed. These should include determinants of breast feeding. A European consensus conference should urgently be organised, in which strategies for successful promotion of exclusive BF should be particularly considered. There is now strong evidence for a recommendation to breast feed exclusively for about 6 months, which is more than the duration recommended previously.

  • 1570.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden.
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden; Department of Physical Education and Health, University of Örebro, Örebro, Sweden:.
    Warm, Daniel
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden; Institue of Human Nutrition, University of Southampton, Southampton, UK.
    Margetts, Barrie
    Institue of Human Nutrition, University of Southampton, Southampton, UK.
    Rodrigo, Carmen Pérez
    Community Nutrition Unit, Department of Public Health, Bilbao, Spain.
    Nissinen, Aulikki
    Department of Community Health and General Practice, University of Kuopio, Kuopio, Finland.
    Effective promotion of healthy nutrition and physical activity in Europe requires skilled and competent people: European Master's Programme in Public Health Nutrition1999In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 2, no 3A, p. 449-452Article in journal (Refereed)
    Abstract [en]

    Scientists in basic research and epidemiology deliver messages to policy makers. Effective population based strategies then require people trained and competent in the discipline of Public Health Nutrition (PHN). Since 1997, a European Master's Programme in PHN has been undergoing planning and implementation with the aid of funding from the European Commission (DGV). PHN is used as a broad term covering Nutrition and Physical Activity as well as Health Promotion and Disease Prevention.

    The partners in this project are academic departments from 17 countries. The students will undertake core modules and electives for a year and a half, followed by a research project for six months. In order to set up formalised procedures for the evaluation of the quality assurance of individual modules from across Europe, a quality assurance system has been set up.

    The academic year 1999-2000 will allow an opportunity for Universities and Institutes to start new modules, to develop other modules, assess the movement of students between modules, tackle funding issues and allow further marketing of the programme. Future activities include strengthening of the European Network for Public Health Nutrition (ENPHN), the establishment of a consortium with universities, the co-ordination of programme activities with other European Master's Programmes in Public Health, and the incorporation of new Member States from Eastern Europe.

    We can look forward to a new brand of professionals, who are truly European in their training, but who also have an integrated view of nutrition and physical activity, health promotion and disease prevention and who are prepared for policy making, action planning, implementation and evaluation.

  • 1571.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden.
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden; Department of Physical Education and Health, University of Örebro, Örebro, Sweden:.
    Warm, Daniel
    Unit for Preventive Nutrition, Department of Biosciences, Karolinska Institutet, Huddinge, Sweden; Institue of Human Nutrition, University of Southampton, Southampton, UK.
    Margetts, Barrie
    Institue of Human Nutrition, University of Southampton, Southampton, UK.
    Rodrigo, Carmen Pérez
    Community Nutrition Unit, Department of Public Health, Bilbao, Spain.
    Nissinen, Aulikki
    Department of Community Health and General Practice, University of Kuopio, Kuopio, Finland.
    Effective promotion of healthy nutrition and physical activity in Europe requires skilled and competent people: European Master's Programme in Public Health Nutrition1999In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 2, no 3A, p. 449-452Article in journal (Refereed)
    Abstract [en]

    Scientists in basic research and epidemiology deliver messages to policy makers. Effective population based strategies then require people trained and competent in the discipline of Public Health Nutrition (PHN). Since 1997, a European Master's Programme in PHN has been undergoing planning and implementation with the aid of funding from the European Commission (DGV). PHN is used as a broad term covering Nutrition and Physical Activity as well as Health Promotion and Disease Prevention.

    The partners in this project are academic departments from 17 countries. The students will undertake core modules and electives for a year and a half, followed by a research project for six months. In order to set up formalised procedures for the evaluation of the quality assurance of individual modules from across Europe, a quality assurance system has been set up.

    The academic year 1999-2000 will allow an opportunity for Universities and Institutes to start new modules, to develop other modules, assess the movement of students between modules, tackle funding issues and allow further marketing of the programme. Future activities include strengthening of the European Network for Public Health Nutrition (ENPHN), the establishment of a consortium with universities, the co-ordination of programme activities with other European Master's Programmes in Public Health, and the incorporation of new Member States from Eastern Europe.

    We can look forward to a new brand of professionals, who are truly European in their training, but who also have an integrated view of nutrition and physical activity, health promotion and disease prevention and who are prepared for policy making, action planning, implementation and evaluation.

  • 1572.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences at Novum, Huddinge, Sweden.
    Strindlund, Åsa
    Unit for Preventive Nutrition, Department of Biosciences at Novum, Huddinge, Sweden.
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences at Novum, Huddinge, Sweden.
    The development of a European master programme in public health nutrition2003In: Forum of nutrition, ISSN 1660-0347, Vol. 56, p. 135-136Article in journal (Refereed)
  • 1573.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Biosciences at Novum, Huddinge, Sweden.
    Strindlund, Åsa
    Unit for Preventive Nutrition, Department of Biosciences at Novum, Huddinge, Sweden.
    Sjöström, Michael
    Unit for Preventive Nutrition, Department of Biosciences at Novum, Huddinge, Sweden.
    The development of a European master programme in public health nutrition2003In: Forum of nutrition, ISSN 1660-0347, Vol. 56, p. 135-136Article in journal (Refereed)
  • 1574.
    Yngve, Agneta
    et al.
    Karolinska Inst, Dept Biosci & Nutr, Unit Publ Hlth Nutr, S-10401 Stockholm, Sweden.
    Thulin, Susanna
    A European network for public health nutrition: The EUNUTNET project2007In: Annals of Nutrition and Metabolism, ISSN 0250-6807, E-ISSN 1421-9697, Vol. 51, p. 321-322Article in journal (Other academic)
  • 1575.
    Yngve, Agneta
    et al.
    Karolinska Inst, Dept Biosci & Nutr, Unit Publ Hlth Nutr, S-10401 Stockholm, Sweden.
    Thulin, Susanna
    A European network for public health nutrition: The EUNUTNET project2007In: Annals of Nutrition and Metabolism, ISSN 0250-6807, E-ISSN 1421-9697, Vol. 51, p. 321-322Article in journal (Other academic)
  • 1576.
    Yngve, Agneta
    et al.
    Karolinska Inst, Dept Biosci & Nutr, Unit Publ Hlth Nutr, S-10401 Stockholm, Sweden.
    Thulin, Susanna
    Karolinska Inst, Dept Biosci & Nutr, Unit Publ Hlth Nutr, S-10401 Stockholm, Sweden.
    Kennedy, Nick
    Trinity Coll Dublin, Dublin, Ireland.
    Margetts, Barrie
    University of Southampton, United Kingdom.
    Thorsdottir, Inga
    Karolinska Inst, Dept Biosci & Nutr, Unit Publ Hlth Nutr, S-10401 Stockholm, Sweden.
    Leonhauser, Ingrid-Ute
    Univ Giessen, D-35390 Giessen, Germany.
    Training in public health nutrition in Europe results from the EUNUTNET project2007In: Annals of Nutrition and Metabolism, ISSN 0250-6807, E-ISSN 1421-9697, Vol. 51, p. 334-335Article in journal (Other academic)
  • 1577.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Inst, Stockholm, Sweden.
    Tseng, Marilyn
    Breastfeeding - still not reaching the target2010In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 13, no 6, p. 749-750Article in journal (Other academic)
  • 1578.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Inst, Stockholm, Sweden.
    Tseng, Marilyn
    Congress in Porto September 2010 and increased impact factor2010In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 13, no 9, p. 1295-1295Article in journal (Other academic)
  • 1579.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Inst, Stockholm, Sweden.
    Tseng, Marilyn
    Dietary guidelines and goal-setting2010In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 13, no 8, p. 1149-1150Article in journal (Other academic)
  • 1580.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Inst, Stockholm, Sweden.
    Tseng, Marilyn
    Salt: importance in iodine deficiency and sodium excess2010In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 13, no 5, p. 599-600Article in journal (Other academic)
  • 1581.
    Yngve, Agneta
    et al.
    Karolinska Inst, Dept Biosci & Nutr, S-10401 Stockholm, Sweden.
    Tseng, Marilyn
    Haapala, Irja
    Hodge, Allison
    A robust and knowledgeable workforce is essential for public health nutrition policy implementation2012In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 15, no 11, p. 1979-1980Article in journal (Other academic)
  • 1582.
    Yngve, Agneta
    et al.
    Department of Bioscience & Nutrition, Karolinska Institute, Stockholm, Sweden.
    Tseng, Marilyn
    Haapala, Irja
    Hodge, Allison
    A robust and knowledgeable workforce is essential for public health nutrition policy implementation2012In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 15, no 11, p. 1979-1980Article in journal (Other academic)
  • 1583.
    Yngve, Agneta
    et al.
    Dept Bioscience & Nutriton, Karolinska Inst, Stockholm, Sweden.
    Tseng, Marilyn
    Haapala, Irja
    Hodge, Allison
    Nutrition of infants and young children2012In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 15, no 9, p. 1601-1602Article in journal (Other academic)
  • 1584.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Inst, Stockholm, Sweden.
    Tseng, Marilyn
    Haapala, Irja
    Hodge, Allison
    McNeill, Geraldine
    The epidemic of obesity publications, award to legend and more2011In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 14, no 1, p. 1-2Article in journal (Other academic)
  • 1585.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Institute, Stockholm, Sweden.
    Tseng, Marilyn
    Haapala, Irja
    McNeill, Caroline
    Hodge, Allison
    Vitamin D - the big D-bate2011In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 14, no 4, p. 565-565Article in journal (Other academic)
  • 1586.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Institute, Stockholm, Sweden.
    Tseng, Marilyn
    Haapala, Irja
    McNeill, Geraldine
    Hodge, Allison
    The local touch2011In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 14, no 6, p. 943-944Article in journal (Other academic)
  • 1587.
    Yngve, Agneta
    et al.
    Karolinska Inst, Novum, Dept Biosci & Nutr, SE-14183 Huddinge, Sweden.
    Tseng, Marilyn
    Hodge, Allison
    Haapala, Irja
    McNeill, Geraldine
    World Nutrition 2012-a global Public Health Nutrition opportunity2012In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 15, no 4, p. 567-567Article in journal (Other academic)
  • 1588.
    Yngve, Agneta
    et al.
    Novum, Dept Bioscience & Nutrition, Karolinska Inst, Huddinge, Sweden.
    Tseng, Marilyn
    Hodge, Allison
    Haapala, Irja
    McNeill, Geraldine
    World Nutrition 2012-a global Public Health Nutrition opportunity2012In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 15, no 4, p. 567-567Article in journal (Other academic)
  • 1589.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Institute, Stockholm, Sweden.
    Tseng, Marilyn
    Hodge, Allison
    McNeill, Geraldine
    Haapala, Irja
    Assessment of diet and physical activity: new tools; old challenges2011In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 14, no 3, p. 377-378Article in journal (Other academic)
  • 1590.
    Yngve, Agneta
    et al.
    Dept Bioscience & Nutrition, Karolinska Inst, Stockholm, Sweden.
    Tseng, Marilyn
    Hodge, Allison
    McNeill, Geraldine
    Haapala, Irja
    Cooking in this issue: back to basics!2012In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 15, no 7, p. 1141-1141Article in journal (Other academic)
  • 1591.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Inst, Stockholm, Sweden.
    Tseng, Marilyn
    Hodge, Allison
    McNeill, Geraldine
    Haapala, Irja
    The fantastic year of 2010 - and the really hot topic: breast-feeding2010In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 13, no 12, p. 1945-1945Article in journal (Other academic)
  • 1592.
    Yngve, Agneta
    et al.
    Dept Bioscience & Nutrition, Karolinska Inst, Stockholm, Sweden.
    Tseng, Marilyn
    McNeill, Caroline
    Haapala, Irja
    Hodge, Allison
    2012-starting with overweight and obesity2012In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 15, no 1, p. 1-2Article in journal (Other academic)
  • 1593. Yngve, Agneta
    et al.
    Tseng, Marilyn
    McNeill, Geraldine
    Haapala, Irja
    Hodge, Allison
    The year that passed: 20112011In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 14, no 12, p. 2081-2082Article in journal (Other academic)
  • 1594.
    Yngve, Agneta
    et al.
    Dept Biosci & Nutr, Karolinska Institute, Stockholm, Sweden.
    Tseng, Marilyn
    McNeill, Geraldine
    Hodge, Allison
    Haapala, Irja
    Is the emperor nude?: impact factor or health impact factor?2011In: Public Health Nutrition, ISSN 1368-9800, E-ISSN 1475-2727, Vol. 14, no 5, p. 753-753Article in journal (Other academic)
  • 1595.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Medical Nutrition/Biosciences, Karolinska Institutet, Stockholm, Sweden;.
    Wolf, Alexandra
    nstitute for Nutritional Sciences, University of Vienna, Vienna, Austria.
    Poortvliet, Eric
    Department of Biosciences, Unit for Preventive Nutrition, Karolinska Institutet, Stockholm, Sweden.
    Elmadfa, Ibrahim
    nstitute for Nutritional Sciences, University of Vienna, Vienna, Austria.
    Brug, Johannes
    Department of Public Health, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
    Ehrenblad, Bettina
    Department of Biosciences, Unit for Preventive Nutrition, Karolinska Institutet, Stockholm, Sweden.
    Franchini, Bela
    Faculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal.
    Haraldsdóttir, Jóhanna
    Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Copenhagen, Denmark.
    Krølner, Rikke
    Department of Social Medicine, Institute of Public Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
    Maes, Lea
    Department of Public Health, Ghent University, Ghent , Belgium.
    Pérez-Rodrigo, Carmen
    Community Nutrition Unit, Bilbao, Spain.
    Sjoström, Michael
    Department of Biosciences, Unit for Preventive Nutrition, Karolinska Institutet, Stockholm, Sweden.
    Thórsdóttir, Inga
    Unit for Nutrition Research, Landspitali University Hospital, Reykjavik, Iceland; Department of Food Science, University of Iceland, Reykjavik, Iceland.
    Klepp, Knut-Inge
    Department of Nutrition, Faculty of Medicine, University of Oslo, Oslo, Norway .
    Fruit and vegetable intake in a sample of 11-year-old children in 9 European countries: the pro children cross-sectional survey2005In: Annals of Nutrition and Metabolism, ISSN 0250-6807, E-ISSN 1421-9697, Vol. 49, no 4, p. 236-245Article in journal (Refereed)
    Abstract [en]

    BACKGROUND/AIMS: An adequate fruit and vegetable intake provides essential nutrients and nutritive compounds and is considered an important part of a healthy lifestyle. No simple instrument has been available for the assessment of fruit and vegetable intake as well as its determinants in school-aged children applicable in different European countries. Within the Pro Children Project, such an instrument has been developed. This paper describes the cross-sectional survey in 11-year-olds in 9 countries.

    METHODS: The cross-sectional survey used nationally, and in 2 countries regionally, representative samples of schools and classes. The questionnaires, including a precoded 24-hour recall component and a food frequency part, were completed in the classroom. Data were treated using common syntax files for portion sizes and for merging of vegetable types into four subgroups.

    RESULTS: The results show that the fruit and vegetable intake in amounts and choice were highly diverse in the 9 participating countries. Vegetable intake was in general lower than fruit intake, boys consumed less fruit and vegetables than girls did. The highest total intake according to the 24-hour recall was found in Austria and Portugal, the lowest in Spain and Iceland.

    CONCLUSION: The fruit and vegetable intake in 11-year-old children was in all countries far from reaching population goals and food-based dietary guidelines on national and international levels.

  • 1596.
    Yngve, Agneta
    et al.
    Unit for Preventive Nutrition, Department of Medical Nutrition/Biosciences, Karolinska Institutet, Stockholm, Sweden;.
    Wolf, Alexandra
    nstitute for Nutritional Sciences, University of Vienna, Vienna, Austria.
    Poortvliet, Eric
    Department of Biosciences, Unit for Preventive Nutrition, Karolinska Institutet, Stockholm, Sweden.
    Elmadfa, Ibrahim
    nstitute for Nutritional Sciences, University of Vienna, Vienna, Austria.
    Brug, Johannes
    Department of Public Health, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
    Ehrenblad, Bettina
    Department of Biosciences, Unit for Preventive Nutrition, Karolinska Institutet, Stockholm, Sweden.
    Franchini, Bela
    Faculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal.
    Haraldsdóttir, Jóhanna
    Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Copenhagen, Denmark.
    Krølner, Rikke
    Department of Social Medicine, Institute of Public Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
    Maes, Lea
    Department of Public Health, Ghent University, Ghent , Belgium.
    Pérez-Rodrigo, Carmen
    Community Nutrition Unit, Bilbao, Spain.
    Sjoström, Michael
    Department of Biosciences, Unit for Preventive Nutrition, Karolinska Institutet, Stockholm, Sweden.
    Thórsdóttir, Inga
    Unit for Nutrition Research, Landspitali University Hospital, Reykjavik, Iceland; Department of Food Science, University of Iceland, Reykjavik, Iceland.
    Klepp, Knut-Inge
    Department of Nutrition, Faculty of Medicine, University of Oslo, Oslo, Norway .
    Fruit and vegetable intake in a sample of 11-year-old children in 9 European countries: the pro children cross-sectional survey2005In: Annals of Nutrition and Metabolism, ISSN 0250-6807, E-ISSN 1421-9697, Vol. 49, no 4, p. 236-245Article in journal (Refereed)
    Abstract [en]

    BACKGROUND/AIMS: An adequate fruit and vegetable intake provides essential nutrients and nutritive compounds and is considered an important part of a healthy lifestyle. No simple instrument has been available for the assessment of fruit and vegetable intake as well as its determinants in school-aged children applicable in different European countries. Within the Pro Children Project, such an instrument has been developed. This paper describes the cross-sectional survey in 11-year-olds in 9 countries.

    METHODS: The cross-sectional survey used nationally, and in 2 countries regionally, representative samples of schools and classes. The questionnaires, including a precoded 24-hour recall component and a food frequency part, were completed in the classroom. Data were treated using common syntax files for portion sizes and for merging of vegetable types into four subgroups.

    RESULTS: The results show that the fruit and vegetable intake in amounts and choice were highly diverse in the 9 participating countries. Vegetable intake was in general lower than fruit intake, boys consumed less fruit and vegetables than girls did. The highest total intake according to the 24-hour recall was found in Austria and Portugal, the lowest in Spain and Iceland.

    CONCLUSION: The fruit and vegetable intake in 11-year-old children was in all countries far from reaching population goals and food-based dietary guidelines on national and international levels.

  • 1597.
    Yuan, Shuai
    et al.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences. Karolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, Nobelsvag 13, S-17177 Stockholm, Sweden.
    Larsson, Susanna C.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics. Karolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, Nobelsvag 13, S-17177 Stockholm, Sweden.
    No association between coffee consumption and risk of atrial fibrillation: A Mendelian randomization study2019In: NMCD. Nutrition Metabolism and Cardiovascular Diseases, ISSN 0939-4753, E-ISSN 1590-3729, Vol. 29, no 11, p. 1185-1188Article in journal (Refereed)
    Abstract [en]

    Background and aims: Some observational studies have found that habitual coffee and caffeine consumption might reduce the risk of atrial fibrillation (AF). We conducted a two-sample Mendelian randomization study to explore the potential association between coffee consumption and AF.

    Methods and results: This study was based on summary-level data from the Atrial Fibrillation Consortium, including 588 190 individuals (65 446 cases and 522 744 non-cases). Nine single-nucleotide polymorphisms associated with coffee consumption at significance level of P < 5 x 10(-8) were used as instrumental variables and were obtained from a genome-wide association study that included up to 375 833 individuals. The odds ratio of AF per genetically-predicted 50% increase of coffee consumption was 0.98 (95% confidence interval, 0.88, 1.10; P = 0.80) in the standard inverse-variance weighted analysis. Results were consistent in sensitivity analyses using the weighted median and MR-Egger methods, and no directional pleiotropy (P = 0.37) was observed. Moreover, complementary analyses that separated the coffee-related single-nucleotide polymorphisms based on their association with blood levels of caffeine metabolites (lower, higher, unrelated or unknown association) revealed no association with AF.

    Conclusions: This study does not support a causal association between habitual coffee consumption and risk of AF. 

  • 1598. Yubero-Serrano, Elena M
    et al.
    Delgado-Lista, Javier
    Tierney, Audrey C
    Perez-Martinez, Pablo
    Garcia-Rios, Antonio
    Alcala-Diaz, Juan F
    Castaño, Justo P
    Tinahones, Francisco J
    Drevon, Christian A
    Defoort, Catherine
    Blaak, Ellen E
    Dembinska-Kieć, Aldona
    Risérus, Ulf
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism.
    Lovegrove, Julie A
    Perez-Jimenez, Francisco
    Roche, Helen M
    Lopez-Miranda, Jose
    Insulin resistance determines a differential response to changes in dietary fat modification on metabolic syndrome risk factors: the LIPGENE study2015In: American Journal of Clinical Nutrition, ISSN 0002-9165, E-ISSN 1938-3207, Vol. 102, no 6, p. 1509-1517Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Previous data support the benefits of reducing dietary saturated fatty acids (SFAs) on insulin resistance (IR) and other metabolic risk factors. However, whether the IR status of those suffering from metabolic syndrome (MetS) affects this response is not established.

    OBJECTIVE: Our objective was to determine whether the degree of IR influences the effect of substituting high-saturated fatty acid (HSFA) diets by isoenergetic alterations in the quality and quantity of dietary fat on MetS risk factors.

    DESIGN: In this single-blind, parallel, controlled, dietary intervention study, MetS subjects (n = 472) from 8 European countries classified by different IR levels according to homeostasis model assessment of insulin resistance (HOMA-IR) were randomly assigned to 4 diets: an HSFA diet; a high-monounsaturated fatty acid (HMUFA) diet; a low-fat, high-complex carbohydrate (LFHCC) diet supplemented with long-chain n-3 polyunsaturated fatty acids (1.2 g/d); or an LFHCC diet supplemented with placebo for 12 wk (control). Anthropometric, lipid, inflammatory, and IR markers were determined.

    RESULTS: Insulin-resistant MetS subjects with the highest HOMA-IR improved IR, with reduced insulin and HOMA-IR concentrations after consumption of the HMUFA and LFHCC n-3 diets (P < 0.05). In contrast, subjects with lower HOMA-IR showed reduced body mass index and waist circumference after consumption of the LFHCC control and LFHCC n-3 diets and increased HDL cholesterol concentrations after consumption of the HMUFA and HSFA diets (P < 0.05). MetS subjects with a low to medium HOMA-IR exhibited reduced blood pressure, triglyceride, and LDL cholesterol levels after the LFHCC n-3 diet and increased apolipoprotein A-I concentrations after consumption of the HMUFA and HSFA diets (all P < 0.05).

    CONCLUSIONS: Insulin-resistant MetS subjects with more metabolic complications responded differently to dietary fat modification, being more susceptible to a health effect from the substitution of SFAs in the HMUFA and LFHCC n-3 diets. Conversely, MetS subjects without IR may be more sensitive to the detrimental effects of HSFA intake. The metabolic phenotype of subjects clearly determines response to the quantity and quality of dietary fat on MetS risk factors, which suggests that targeted and personalized dietary therapies may be of value for its different metabolic features. This study was registered at clinicaltrials.gov as NCT00429195.

  • 1599.
    Zamaratskaia, Galia
    et al.
    Swedish Univ Agr Sci SLU, Dept Mol Sci, BioCtr, S-75007 Uppsala, Sweden..
    Johansson, Daniel P.
    Swedish Univ Agr Sci SLU, Dept Mol Sci, BioCtr, S-75007 Uppsala, Sweden..
    Junqueira, Matheus Antunes
    Swedish Univ Agr Sci SLU, Dept Mol Sci, BioCtr, S-75007 Uppsala, Sweden..
    Deissler, Linda
    Swedish Univ Agr Sci SLU, Dept Mol Sci, BioCtr, S-75007 Uppsala, Sweden.;Univ Hohenheim, Inst Biol Chem & Nutr, Garbenstr 28, D-70599 Stuttgart, Germany..
    Langton, Maud
    Swedish Univ Agr Sci SLU, Dept Mol Sci, BioCtr, S-75007 Uppsala, Sweden..
    Hellström, Per M.
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Gastroenterology/Hepatology.
    Landberg, Rikard
    Swedish Univ Agr Sci SLU, Dept Mol Sci, BioCtr, S-75007 Uppsala, Sweden.;Karolinska Inst, Dept Environm Med, Unit Nutr Epidemiol, S-17177 Stockholm, Sweden.;Chalmers Univ Technol, Dept Biol & Biol Engn, Gothenburg, Sweden..
    Impact of sourdough fermentation on appetite and postprandial metabolic responses - a randomised cross-over trial with whole grain rye crispbread2017In: British Journal of Nutrition, ISSN 0007-1145, E-ISSN 1475-2662, Vol. 118, no 9, p. 686-697Article in journal (Refereed)
    Abstract [en]

    Sourdough fermentation is considered to have beneficial effects on postprandial satiety and metabolic responses, but studies demonstrating effects at physiological conditions are lacking. The aim of this acute breakfast intervention study was to determine the effect of consumption of sourdough-fermented and unfermented rye crispbread on self-rated appetite, postprandial glucose and insulin response in healthy subjects. In all, twenty-four Swedish adults were included in a single-blinded, randomised cross-over trial. Three crispbreads (sourdough-fermented and unfermented whole grain rye and yeast-fermented refined wheat as control) were consumed as part of a standardised breakfast. Subjective appetite score, assessed using visual analogue scale, and plasma glucose and insulin concentrations were measured at baseline and postprandially until 360 and 240 min, respectively. Structural changes and viscosity during mastication and gastric digestion were investigated using in vitro methods. Hunger and desire to eat were lower (P<005) based on AUC measurements after intake of sourdough-fermented rye crispbread compared with after intake of yeast-fermented refined wheat crispbread. On the basis of AUC (0-230 min), insulin response was lowest after intake of unfermented rye crispbread compared with sourdough-fermented rye and yeast-fermented refined wheat crispbread. Degradation of viscous fibres and faster bolus disintegration for the sourdough-fermented bread may partly explain the less favourable metabolic responses compared with unfermented bread. Our results showed that food processing affects the composition and structural characteristics of rye bread, which has implications for appetite and metabolic responses.

  • 1600.
    Zamaratskaia, Galia
    et al.
    Swedish University of Agricultural Sciences, Department of Molecular Sciences, Box, 7015, Uppsala, Sweden..
    Mhd Omar, Nor Adila
    Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden. .
    Brunius, Carl
    Swedish University of Agricultural Sciences, Department of Molecular Sciences, Box, 7015, Uppsala, Sweden; Department of Biology and Biological Engineering, Division of Food and Nutrition Science, Chalmers University of Technology, Gothenburg, Sweden..
    Hallmans, Göran
    Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden..
    Johansson, Jan-Erik
    Department of Urology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden..
    Andersson, Sven-Olof
    Larsson, Anders
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Chemistry.
    Åman, Per
    Swedish University of Agricultural Sciences, Department of Molecular Sciences, Box, 7015, Uppsala, Sweden..
    Landberg, Rikard
    Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden; Department of Biology and Biological Engineering, Division of Food and Nutrition Science, Chalmers University of Technology, Gothenburg, Sweden..
    Consumption of whole grain/bran rye instead of refined wheat decrease concentrations of TNF-R2, e-selectin, and endostatin in an exploratory study in men with prostate cancer2019In: Clinical Nutrition, ISSN 0261-5614, E-ISSN 1532-1983Article in journal (Refereed)
    Abstract [en]

    BACKGROUND & AIMS: Rye consumption has shown beneficial effects on prostate cancer tumors, as indicated by slower initial tumor growth in animal models and lowering of prostate-specific antigen (PSA) in humans. This study evaluated the effects of whole grain/bran rye consumption on low-grade inflammation and endothelial function biomarkers in men with prostate cancer.

    METHODS: Seventeen men with untreated, low-grade prostate cancer consumed 485 g rye whole grain and bran products (RP) per day or refined wheat products with added cellulose (WP) in a randomized crossover design. Fasting blood samples were taken before and after 2, 4, and 6 weeks of treatment.

    RESULTS: Concentrations of tumor nuclear factor-receptor 2 (TNF-R2), e-selectin, and endostatin were significantly lower after consumption of the RP diet compared with WP (p < 0.05). Cathepsin S concentration was positively correlated to TNF-R2 and endostatin concentrations across all occasions. Strong correlations were consistently found between intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) and between interleukin-6 (IL-6) and interleukin-1 receptor antagonist (IL-1RA). No effect of intervention was found in 92 inflammation-related protein biomarkers measured in a proximity extension assay.

    CONCLUSIONS: RP diet lowered TNF-R2, e-selectin, and endostatin, compared with WP in men with prostate cancer. These effects were accompanied by a reduction in PSA.

2930313233 1551 - 1600 of 1628
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