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  • 1157801. Yen, Jonathan
    et al.
    Carlsson, Mats
    RISE, Swedish ICT, SICS, Computer Systems Laboratory.
    Chang, Mike
    Garcia, Joan Manel
    Nguyen, Hugh
    Constraint solving for inkjet print mask design1998Other (Other academic)
  • 1157802.
    Yen, Jonathan
    et al.
    Hewlett-Packard Research Laboratory.
    Maguire Jr., Gerald Q.
    KTH, School of Information and Communication Technology (ICT), Communication Systems, CoS.
    Saw, Chit Wei
    Hewlett-Packard Research Laboratory.
    Yihong, Xu
    Hewlett-Packard Research Laboratory.
    Authenticatable graphical bar codes2000Patent (Other (popular science, discussion, etc.))
    Abstract [en]

    Systems and methods for generating and decoding authenticatable graphical bar codes are described. In one aspect, a corroborative signed message is generated from information to be encoded, and a base image is modulated with a graphical encoding of the signed message to produce a marked image. In another aspect, a signed message is extracted from a marked image based upon a comparison of the marked image and a base image. The extracted signed message is decoded to produce a decoded message. Information encoded in the marked image is extracted from the decoded message and authenticated.

  • 1157803.
    Yen, Jonathan
    et al.
    Hewlett-Packard Research Laboratory.
    Maguire Jr., Gerald Q.
    KTH, School of Information and Communication Technology (ICT), Communication Systems, CoS.
    Saw, Chit Wei
    Hewlett-Packard Research Laboratory.
    Yihong, Xu
    Hewlett-Packard Research Laboratory.
    Method of encoding a handwritten signature2000Patent (Other (popular science, discussion, etc.))
    Abstract [en]

    Systems and methods for generating and decoding authenticatable graphical bar codes are described. In one aspect, a corroborative signed message is generated from information (12) to be encoded, and a base image (22) is modulated with a graphical encoding of the signed message to produce a marked image (14). In another aspect, a signed message is extracted from a marked image (14) and a base image (22). The extracted signed message is decoded to produce a decoded message. Information (12) encoded in the marked image (14) is extracted from the decoded message and authenticated.

  • 1157804. Yen, MA
    et al.
    Tabar, L
    Vitak, B
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Radiology. Östergötlands Läns Landsting, Centre for Medical Imaging, Department of Radiology UHL.
    Smith, RA
    Chen, HH
    Duffy, SW
    Quantifying the potential problem of overdiagnosis of ductal carcinoma in situ in breast cancer screening2003In: European Journal of Cancer, ISSN 0959-8049, E-ISSN 1879-0852, Vol. 39, no 12, p. 1746-1754Article in journal (Refereed)
    Abstract [en]

    The relevance of detection of ductal carcinoma in situ (DCIS) in a breast cancer screening programme, and the extent of overdiagnosis of non-progressive lesions, remains controversial. It was the purpose of this paper to estimate the incidence of non-progressive, 'overdiagnosed' DCIS. We defined non-progressive DCIS (DCIS0) as DCIS which could not have progressed to invasive disease if left untreated. Progressive DCIS (DCIS1) was defined as DCIS which has the propensity to progress to invasive disease. We fitted a Markov process model of the incidence of progressive and non-progressive DCIS, the transition of the former to preclinical invasive disease and the subsequent progression to clinical symptomatic cancer. We used data from the Swedish Two-County Trial and from service screening programmes in the UK, Netherlands, Australia and the USA to estimate the incidence of progressive and non-progressive DCIS, and the detection rates of each at the first and subsequent screening. Average incidence of non-progressive DCIS was 1.11 per 100 000 per year. Average incidence of progressive DCIS was 2.1 per 1000 per year. At prevalence screen, 37% of DCIS cases were estimated to be non-progressive. A woman attending prevalence screen has a 19 times greater chance of having a progressive DCIS or an invasive tumour diagnosed than of having a non-progressive DCIS diagnosed. At incidence screen, only 4% of DCIS cases were estimated to be non-progressive. A woman attending an incidence screen has a 166 times higher probability of having a progressive DCIS or invasive lesion diagnosed than of having a non-progressive DCIS diagnosed. There is an element of overdiagnosis of DCIS in breast cancer screening, but the phenomenon is small in both relative and absolute terms. ⌐ 2003 Elsevier Ltd. All rights reserved.

  • 1157805.
    Yen Panya, Saran
    University College of Arts, Crafts and Design, The Department of Design, Crafts and Art (DKK), Graphic Design & Illustration.
    Degree report2011Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 1157806. Yenamandra, Surya Pavan
    et al.
    Hellman, Ulf
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm , Ludwig Institute for Cancer Research.
    Kempkes, Bettina
    Darekar, Suhas Deoram
    Petermann, Sabine
    Sculley, Tom
    Klein, George
    Kashuba, Elena
    Epstein-Barr virus encoded EBNA-3 binds to vitamin D receptor and blocks activation of its target genes2010In: Cellular and Molecular Life Sciences (CMLS), ISSN 1420-682X, E-ISSN 1420-9071, Vol. 67, no 24, p. 4249-4256Article in journal (Refereed)
    Abstract [en]

    Epstein-Barr virus (EBV) is a human gamma herpes virus that infects B cells and induces their transformation into immortalized lymphoblasts that can grow as cell lines (LCLs) in vitro. EBNA-3 is a member of the EBNA-3-protein family that can regulate transcription of cellular and viral genes. The identification of EBNA-3 cellular partners and a study of its influence on cellular pathways are important for understanding the transforming action of the virus. In this work, we have identified the vitamin D receptor (VDR) protein as a binding partner of EBNA-3. We found that EBNA3 blocks the activation of VDR-dependent genes and protects LCLs against vitamin-D3-induced growth arrest and/or apoptosis. The presented data shed some light on the anti-apoptotic EBV program and the role of the EBNA-3-VDR interaction in the viral strategy.

  • 1157807.
    Yeneneh, Getu Temasgen
    Dalarna University, School of Technology and Business Studies, Energy Technology.
    Testing of Apis System Platform in Grid-Connected Photovoltaic System and Comparison with Metrum for Fault Detection and Diagnosis2016Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    A real time data management web-based software-platform for PV plant monitoring called Apis was tested for fault detection and diagnosis of large scale grid-connected photovoltaic systems. This method was compared with Metrum system which is also another web based monitoring system used in grid connected PV systems. The objective of testing and comparisons were to observe the Apis system performance in large scale PV systems particularly for fault detection, and to identify which of the two systems could give more information to easily identify type of fault and point out the fault location in PV plants.

    The experiment were carried out in the selected two different arrays that have a capacity of 18.4kW and 17.6 kW with four string inverters each, to test three cases at Glava energy center solar park, Sweden. The first demonstrates the response of the systems when the wiring loose or cable disconnection fault occurs in the plant. The second demonstrates the output of the inverters when partial shading is gradually increased and the third demonstrates the output when the fault at components (i.e. at inverter, fuse and circuit breaker) is applied. Both systems collect data from inverters. However, in Apis system, data from individual inverters of the plant could be collected separately in both AC and DC sides while Metrum system was measuring the total output of the whole inverters in the plant.

    During the string disconnection, the Apis monitoring system showed a power drop to zero from the defected strings making it possible to identify them. In the same way during the inverters’ fault the power output of the failed inverter was dropped to zero. However, the normal strings and inverters were still working properly. Meanwhile the Metrum system only displayed a reduced power output which doesn’t directly identify the problem and requires manual inspection. In the case of partial shading there was a persistent difference occurred between the defected string and normal one but it did not dropped to zero at all.

    Apis system is able to differentiate and locate the faults by comparing input and output results of different inverters within the plant, unlike Metrum system which measures the total output of the plant. Nevertheless, Apis system still has less possibility to determine the type of fault further than estimation.

  • 1157808.
    Yenga Muhindo, Georges
    et al.
    Mälardalen University, School of Sustainable Development of Society and Technology.
    Guliyeva, Gulafat
    Corporate Social Responsibility: Hur några svenska storbankers CSR-arbete implementerats på lokal nivå och vilka effekter som orsakats av CSR-arbetet på samma nivå2010Independent thesis Advanced level (degree of Master (One Year)), 15 credits / 22,5 HE creditsStudent thesis
    Abstract [en]

    ABSTRACT

    Title: Corporate Social Responsibility, How some major Swedish banks’ CSR work implemented at local level and which effects caused by CSR Work at the same level.

    Course: Master thesis in business administration, FÖA 400, 15 Swedish credits

    Authors: Gulafat Guliyeva gga09001@student.mdh.se

    Georges Yenga Muhindo gya09001@student.mdh.se

    Seminar date: 2010-09-30

    Supervisor: Esbjörn Segelod

    Keywords: CSR, Social Responsibility, business ethics

    Purpose: The purpose of this paper is to examine how some major Swedish banks’ CSR work has been implemented at the local level. In addition we want also to examine the effects caused by the CSR work at the local level.

    Methodology: Data has been collected through interviews guided by a list of openeded questions and a webbased survey (Survey Monkey).

    Conclusions:

     

    We found that group’s global policies in the field of CSR is im- plemented at the local level in the form of guidelines, directives and values that local office managers apply in their daily activities.

    We noticed that the credit policy and the credit process are one of the main instruments through which CSR work is implemented.

    There are still some lacks regarding the important internal instrument that was unintelligible for a part of local office managers.

    In addition, it has been impossible to confirm any implementation of CSR work for some of local bank offices.

    Concerning effects we noticed that some banks have a positive or a limited impact in the areas where they operate. The reason to the limited effect is a inadequate marketing budget at the local level. There was also no specific projects for one bank while it has been impossible to find effects for another bank.

     

     

  • 1157809.
    Yenge Massa, Noela
    et al.
    Karlstad University, Faculty of Arts and Social Sciences (starting 2013), Karlstad Business School (from 2013).
    Karlsson, Per
    Karlstad University, Faculty of Arts and Social Sciences (starting 2013), Karlstad Business School (from 2013).
    The factors influencing students’ career choices towards the accounting profession in Sweden2018Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    Purpose – This thesis aimed at investigating students’ beliefs influencing their personal attitudes and subjective norms not to choose the accounting profession by using the simplified Theory of Reasoned Action (TRA) model.

    Theoretical framework – This study used the simplified TRA model to investigate the beliefs that influence students not to choose the accounting profession. From an accounting context, prior research has indicated that, there are intrinsic and extrinsic factors that determine the behavioural beliefs of students about the accounting profession. Likewise, normative beliefs are another construct of the simplified TRA model that influences students’ intentions towards the accounting profession.

    Methodology – Through a quantitative approach, questionnaires were sent electronically to first and second year students at five major universities in Sweden. In total, 323 students replied to the questionnaire. Since this study focused on students intending to choose business administration, non-business administration students were deleted from the sample giving an actual sample size of 228. The data collected was analyzed in two steps using multiple regression analysis.

    Findings – The findings of the study confirmed the simplified TRA model. The results showed that both behavioural and normative beliefs influenced students’ intentions not to choose the accounting profession. For behavioral beliefs, no personal interest in accounting, the belief that accounting is boring and the belief that other occupations (for instance, marketing and management) negatively influenced students’ attitudes not to choose the accounting profession. Similarly, for normative beliefs, teachers and peers influenced students’ subjective norms not to choose the accounting profession.

    Practical implications – The practical implications of this study are two-folded. Firstly, program directors at universities should engage in hiring qualified teachers in accounting, organize supportive activities to encourage students about the accounting profession. Also, program directors should include compulsory internships in the curriculum so that students can learn about the accounting profession. Secondly, former accounting students should get involved in the process of encouraging students about the accounting profession.

    Originality/value – This paper contributes to the existing literature by highlighting the beliefs influencing the personal attitudes and subjective norms of students not to choose the accounting profession. Therefore, the thesis provides an up-to-date theory about the TRA in the accounting profession in Sweden.

  • 1157810. Yenigun, Behiye
    Olämpliga föräldrar i fråga om umgänge och vårdnad2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 1157811.
    Yenigun, Cigdem
    University of Gävle, Faculty of Health and Occupational Studies, Department of Occupational and Public Health Sciences.
    Arbetslöshetens inverkan på nyanlända: En studie om eftergymnasialt utbildade nyanländas upplevelser av arbetslöshet2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    The purpose of this study was to examine mental health in relation to unemployment among newly arrived with post-secondary education. This was to get a deeper understanding about their experiences regarding unemployment despite their high education, the focus was on mental health and how they think their future looks like. The method used for the following study was an empirical qualitative method in which the author used the semi-structured interviews. Five participants were interviewed, four men and one woman between the ages 20-64. The results of this study found that newly arrived people with post-secondary education had poor mental health because of worries about the future. They also felt that the education they had received from their country was a waste in Sweden. These people also had a temporary residence permit which brought frustration because their future wasn’t secure. The conclusion of this study was that newly arrived individuals with post-secondary education wanted Psychological help from the society so they could start working. 

  • 1157812.
    Yeniler, Ulrika
    Halmstad University, School of Humanities (HUM).
    L'assistant Comenius: une ressource à l'école?2010Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [fr]

    Dans le cadre du projet de l’UE sur la formation tout au long de la vie, les écoles peuvent demander des subventions pour différents projets pédagogiques. Il y a beaucoup d’argent disponible. La fait d’accueillir un assistant Comenius á son école pour une période limitée est un projet possible. En Suède, 42 écoles ont reçu une subvention pour accueillir un assistant Comenius en automne 2009.

    Dans cette étude, nous cherchons à savoir si l’assistant Comenius peut aider les élèves à atteindre les objectifs de école. Pour des raisons d’ordre pratique nous nous sommes limitée à la compréhension orale  en langues vivantes. Porcher (1995, p. 46) note que la compréhension orale constitue une condition nécessaire à l’autonomie d l’élève et qu’elle doit être un souci dominant des enseignants et des programmes scolaires, Notre étude repose sur une enquête réalisée auprès des enseignants et des élèves dans des écoles qui ont accueilli un assistant.

    Toutes les phrases en italique sont notre traduction. Les commentaires des informateurs qui sont cités dans ce travail sont également notre traduction.

  • 1157813.
    Yenioglu, Melisa
    et al.
    Mälardalen University, School of Health, Care and Social Welfare.
    Strand, Johan
    Mälardalen University, School of Health, Care and Social Welfare.
    Synen på kuratorns roll i skolan: - Från kurator till elev2019Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 1157814.
    Yennego Jr, Zubah Kollie
    et al.
    Linnaeus University, School of Business and Economics, Department of Management Accounting and Logistics.
    Blomstervall, Fredrik
    Linnaeus University, School of Business and Economics, Department of Management Accounting and Logistics.
    Rasmussen, Markus
    Linnaeus University, School of Business and Economics, Department of Management Accounting and Logistics.
    Purchasing Process of Services: A Study of the Purchasing Process of Human Resource (HR) Services2017Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Title: Purchasing Process of Services: A Study of the Purchasing Process of HumanResource (HR) services

    Background: The rise in competition among organizations continues to increase. The rise in globalization, outsourcing and continuous pressure from customers have been the source for the increase in competition. Additionally, the instability in various industries is leading to high competition among firms. The purchasing of professional services is vital to organizations. Contemporary organizations spend a huge portion of their resources on the purchasing of professional services. The proper purchase of professional services can lead to cost saving and competitive advantage for companies or organizations.

    Research Questions: 

    • How can the various purchasing models be used to develop a process for professional HR service purchasing?
    • What are the factors involved in developing a process for the purchasing of professional HR services

    Purpose: The purpose of this thesis is to develop a purchasing process for the purchasing of professional HR services. It takes into consideration the various classifications models of purchasing and the factors involved in the purchasing of services in order to develop a purchasing process for professional HR services.

    Method: Through a qualitative case study, the thesis gathered empirical data and used the deductive scientific approach to building a foundation of theory. Additionally, pattern matching was used to analyze both the theory and empirical data.

    Conclusion: The thesis developed a new classification model for HR services which resulted in the development of a new purchasing process that takes into consideration the classification of services and integrates the effects of the classification in the purchasing process. Additionally, the thesis discovered that personal relationship, clarity of problem and solution, specification of supplier’s inputs, specification of supplier’s throughputs or processes, specification of supplier’s output and specification of supplier’s outcome and the characteristics of service are factors involved in the development of a purchasing process forHR Services.

    Keywords: Professional Human Resource Services, Categorization of service, PurchasingModels, Service Purchasing Process

  • 1157815.
    Yentrapalli, Ramesh
    et al.
    Stockholm University, Faculty of Science, Department of Genetics, Microbiology and Toxicology. Helmholtz Zentrum München .
    Azimzadeh, Omid
    Barjaktarovic, Zarko
    Sarioglu, Hakan
    Wojcik, Andrzej
    Stockholm University, Faculty of Science, Department of Genetics, Microbiology and Toxicology.
    Harms-Ringdahl, Mats
    Stockholm University, Faculty of Science, Department of Genetics, Microbiology and Toxicology.
    Atkinson, Michael J.
    Haghdoost, Siamak
    Stockholm University, Faculty of Science, Department of Genetics, Microbiology and Toxicology.
    Tapio, Soile
    Quantitative proteomic analysis reveals induction of premature senescence in human umbilical vein endothelial cells exposed to chronic low-dose rate gamma radiation2013In: Proteomics, ISSN 1615-9853, E-ISSN 1615-9861, Vol. 13, no 7, p. 1096-1107Article in journal (Refereed)
    Abstract [en]

    Chronic low-dose ionizing radiation induces cardiovascular disease in human populations but the mechanism is largely unknown. We suggested that chronic radiation exposure may induce endothelial cell senescence that is associated with vascular damage in vivo. We investigated whether chronic radiation exposure is causing a change in the onset of senescence in endothelial cells in vitro. Indeed, when exposed to continuous low-dose rate gamma radiation (4.1 mGy/h), primary human umbilical vein endothelial cells (HUVECs) initiated senescence much earlier than the nonirradiated control cells. We investigated the changes in the protein expression of HUVECs before and during the onset of radiation-induced senescence. Cellular proteins were quantified using isotope-coded protein label technology after 1, 3, and 6 weeks of radiation exposure. Several senescence-related biological pathways were influenced by radiation, including cytoskeletal organization, cellcell communication and adhesion, and inflammation. Immunoblot analysis showed an activation of the p53/p21 pathway corresponding to the progressing senescence. Our data suggest that chronic radiation-induced DNA damage and oxidative stress result in induction of p53/p21 pathway that inhibits the replicative potential of HUVECs and leads to premature senescence. This study contributes to the understanding of the increased risk of cardiovascular diseases seen in populations exposed to chronic low-dose irradiation.

  • 1157816.
    Yentrapalli, Ramesh
    et al.
    Stockholm University, Faculty of Science, Department of Molecular Biosciences, The Wenner-Gren Institute. Helmholtz Zentrum München.
    Azimzadeh, Omid
    Sriharshan, Arundhathi
    Malinowsky, Katharina
    Merl, Juliane
    Wojcik, Andrzej
    Stockholm University, Faculty of Science, Department of Molecular Biosciences, The Wenner-Gren Institute.
    Harms-Ringdahl, Mats
    Stockholm University, Faculty of Science, Department of Molecular Biosciences, The Wenner-Gren Institute.
    Atkinson, Michael J.
    Becker, Karl-Friedrich
    Haghdoost, Siamak
    Stockholm University, Faculty of Science, Department of Molecular Biosciences, The Wenner-Gren Institute.
    Tapio, Soile
    The PI3K/Akt/mTOR Pathway Is Implicated in the Premature Senescence of Primary Human Endothelial Cells Exposed to Chronic Radiation2013In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 8, no 8, p. e70024-Article in journal (Refereed)
    Abstract [en]

    The etiology of radiation-induced cardiovascular disease (CVD) after chronic exposure to low doses of ionizing radiation is only marginally understood. We have previously shown that a chronic low-dose rate exposure (4.1 mGy/h) causes human umbilical vein endothelial cells (HUVECs) to prematurely senesce. We now show that a dose rate of 2.4 mGy/h is also able to trigger premature senescence in HUVECs, primarily indicated by a loss of growth potential and the appearance of the senescence-associated markers ß-galactosidase (SA-ß-gal) and p21. In contrast, a lower dose rate of 1.4 mGy/h was not sufficient to inhibit cellular growth or increase SA-ß-gal-staining despite an increased expression of p21. We used reverse phase protein arrays and triplex Isotope Coded Protein Labeling with LC-ESI-MS/MS to study the proteomic changes associated with chronic radiation-induced senescence. Both technologies identified inactivation of the PI3K/Akt/mTOR pathway accompanying premature senescence. In addition, expression of proteins involved in cytoskeletal structure and EIF2 signaling was reduced. Age-related diseases such as CVD have been previously associated with increased endothelial cell senescence. We postulate that a similar endothelial aging may contribute to the increased rate of CVD seen in populations chronically exposed to low-dose-rate radiation.

  • 1157817.
    Yentrapalli, Venkata ramesh
    Stockholm University, Faculty of Science, Department of Genetics, Microbiology and Toxicology.
    Chronic low-dose gamma radiation exposure induces premature senescence in human umbilical vein endothelial cellsManuscript (preprint) (Other academic)
  • 1157818.
    Yentrapalli, Venkata Ramesh
    Stockholm University, Faculty of Science, Department of Genetics, Microbiology and Toxicology.
    Mechanism behind the development of radiation-induced cardiovascular effects2012Licentiate thesis, comprehensive summary (Other academic)
    Abstract [en]

    Epidemiological studies on acutely and chronically exposed individuals indicate that ionising radiation could be a risk factor for cardiovascular diseases. Experimental data regarding radiation-induced cardiovascular late effects are limited and biological mechanisms behind these late effects are still unclear. The estimation of risks concerning low-dose rate and low-dose ionising radiation is still challenging due to lack of experimental evidence.

    The first paper of the thesis describes the radiation-induced protein alterations in cardiac tissue of total body irradiated mice. We use a label-free proteomic approach to identify altered proteins from formalin-fixed paraffin-embedded heart tissue. Comparison between the cardiac proteomes of control and irradiated mice indicates the respiratory chain, lipid metabolism and pyruvate metabolism pathways are affected. We suggest that these biological processes may play a vital role in radiation-induced cardiovascular diseases.

    In the second paper (manuscript) we hypothesized that chronic low-dose rate ionising radiation accelerates premature senescence in endothelial cells and that this may contribute to the radiation-induced cardiovascular diseases. We tested our hypothesis by systematically analysing the growth rate, the number of accumulated senescent cells and the protein expression profiles of the chronically exposed primary human umbilical vein endothelial cells until the cells entered senescence. Decrease in cumulative population doublings and increase in senescent-associated beta-galactosidase stained cells show that chronic exposure to radiation accelerates endothelial cells senescence. Our proteomic results suggest that the cytoskeletal organisation, cell-cell communication and adhesion, inflammation and carbohydrate metabolism were influenced by chronic exposure to radiation. A few deregulated proteins have previously been associated with replicative and stress-induced premature senescence. The results presented here provide new insights on radiation-induced premature senescence in endothelial cells and the changes in protein expression associated with this process.

  • 1157819.
    Yentrapalli, Venkata Ramesh
    Stockholm University, Faculty of Science, Department of Molecular Biosciences, The Wenner-Gren Institute.
    Novel radiation targets in the endothelium and heart muscle2013Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Worldwide, people are being exposed to natural and man-made sources of radiation. Epidemiological studies have shown an increased risk of vascular diseases in populations that have been exposed to ionizing radiation. Vascular endothelium is implicated as one of the targets for radiation leading to the development of cardiovascular diseases. However, the molecular mechanisms behind the development of radiation-induced cardiovascular disease in acute or chronic exposed people are not fully elucidated. The hypothesis that chronic low dose rate ionizing radiation accelerates the onset of senescence of primary human umbilical vein endothelial cells has been tested in papers I and II presented in this thesis. In vitro studies show that, when exposed to continuous low dose rate gamma radiation these cells enter premature senescence much earlier than non-irradiated control cells. Quantitative proteomic analysis using isotope coded protein labeling coupled to LC-ESI-mass spectrometry and followed by protein network analysis identified changes in senescence-related biological pathways including cytoskeletal organisation, cell-cell communication and adhesion, and inflammation influenced by radiation. Moreover, the role of PI3K/Akt/mTOR pathway was implicated during the senescence process. Thus, chronic low dose rated endothelial senescence may contribute to increased risk of radiation-induced cardiovascular disease.

    Paper III analyse the long-term effects of local high doses of radiation to the heart using a mouse model. The results from proteomic and bioinformatics analysis indicated that an impaired activity of the peroxisome proliferator-activated receptor-alpha (PPARA) is involved in mediating the radiation response. Ionizing radiation markedly changed the phosphorylation and ubiquitination status of PPARA. This was reflected by the decreased expression of PPARA target genes involved in energy metabolism and mitochondrial respiratory chain. This in vivo study suggests that alteration of cardiac metabolism contributes to the impairment of heart structure and function after radiation.

    Taken together, these in vitro and in vivo studies provide novel information on the pathways in heart and endothelial cells that are affected over longer periods of time by ionizing radiation.

  • 1157820.
    Yeo, Andy
    Royal College of Music in Stockholm, Department of Jazz.
    Om improvisation och att hitta tillbaka till mina rötter2013Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 1157821.
    Yeo, Astrid
    et al.
    GlaxoSmithKline Med Res Ctr, Dept Genet, Stevenage, Herts, England..
    Li, Li
    GlaxoSmithKline Med Res Ctr, Dept Genet, Res Triangle Pk, NC USA.;PAREXEL Int, Genom Med, Durham, NC USA..
    Warren, Liling
    GlaxoSmithKline Med Res Ctr, Dept Genet, Res Triangle Pk, NC USA.;Teva Pharmaceut, Raleigh, NC USA..
    Aponte, Jennifer
    GlaxoSmithKline Med Res Ctr, Dept Genet, Res Triangle Pk, NC USA.;PAREXEL Int, Genom Med, Durham, NC USA..
    Fraser, Dana
    GlaxoSmithKline Med Res Ctr, Dept Genet, Res Triangle Pk, NC USA.;PAREXEL Int, Genom Med, Durham, NC USA..
    King, Karen
    GlaxoSmithKline Med Res Ctr, Dept Genet, Res Triangle Pk, NC USA.;PAREXEL Int, Genom Med, Durham, NC USA..
    Johansson, Kelley
    GlaxoSmithKline Med Res Ctr, Dept Genet, Res Triangle Pk, NC USA.;PAREXEL Int, Genom Med, Durham, NC USA..
    Barnes, Allison
    GlaxoSmithKline Med Res Ctr, Clin Stat, Res Triangle Pk, NC USA.;PAREXEL Int, Biostat, Durham, NC USA..
    MacPhee, Colin
    GlaxoSmithKline Med Res Ctr, Dept Vasc Biol & Thrombosis, King Of Prussia, PA USA..
    Davies, Richard
    GlaxoSmithKline Med Res Ctr, Metab Pathways & Cardiovasc Therapeut Area, King Of Prussia, PA USA..
    Chissoe, Stephanie
    GlaxoSmithKline Med Res Ctr, Dept Genet, Res Triangle Pk, NC USA.;GlaxoSmithKline, Elliott Ave, Seattle, WA USA..
    Tarka, Elizabeth
    GlaxoSmithKline Med Res Ctr, Metab Pathways & Cardiovasc Therapeut Area, King Of Prussia, PA USA.;Janssen Pharmaceut, Spring House, PA USA..
    O'Donoghue, Michelle L.
    Brigham & Womens Hosp, Div Cardiovasc, TIMI Study Grp, 75 Francis St, Boston, MA 02115 USA..
    White, Harvey D.
    Auckland City Hosp, Green Lane Cardiovasc Serv, Auckland, New Zealand.;Univ Auckland, Auckland, New Zealand..
    Wallentin, Lars
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Cardiology. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, UCR-Uppsala Clinical Research Center.
    Waterworth, Dawn
    GlaxoSmithKline Med Res Ctr, Dept Genet, Philadelphia, PA USA..
    Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib2017In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 12, no 7, article id e0182115Article in journal (Refereed)
    Abstract [en]

    Darapladib, a lipoprotein-associated phospholipase A2 (Lp-PLA(2)) inhibitor, failed to demonstrate efficacy for the primary endpoints in two large phase III cardiovascular outcomes trials, one in stable coronary heart disease patients (STABILITY) and one in acute coronary syndrome (SOLID-TIMI 52). No major safety signals were observed but tolerability issues of diarrhea and odor were common (up to 13%). We hypothesized that genetic variants associated with Lp-PLA(2) activity may influence efficacy and tolerability and therefore performed a comprehensive pharmacogenetic analysis of both trials. We genotyped patients within the STABILITY and SOLID-TIMI 52 trials who provided a DNA sample and consent (n = 13,577 and 10,404 respectively, representing 86% and 82% of the trial participants) using genomewide arrays with exome content and performed imputation using a 1000 Genomes reference panel. We investigated baseline and change from baseline in Lp-PLA(2) activity, two efficacy endpoints (major coronary events and myocardial infarction) as well as tolerability parameters at genome-wide and candidate gene level using a meta-analytic approach. We replicated associations of published loci on baseline Lp-PLA2 activity (APOE, CELSR2, LPA, PLA2G7, LDLR and SCARB1) and identified three novel loci (TOMM5, FRMD5 and LPL) using the GWAS-significance threshold P <= 5E-08. Review of the PLA2G7 gene (encoding Lp-PLA(2)) within these datasets identified V279F null allele carriers as well as three other rare exonic null alleles within various ethnic groups, however none of these variants nor any other loci associated with Lp-PLA(2) activity at baseline were associated with any of the drug response endpoints. The analysis of darapladib efficacy endpoints, despite low power, identified six low frequency loci with main genotype effect (though with borderline imputation scores) and one common locus (minor allele frequency 0.24) with genotype by treatment interaction effect passing the GWAS-significance threshold. This locus conferred risk in placebo subjects, hazard ratio (HR) 1.22 with 95% confidence interval (CI) 1.11-1.33, but was protective in darapladib subjects, HR 0.79 ( 95% CI 0.71-0.88). No major loci for tolerability were found. Thus, genetic analysis confirmed and extended the influence of lipoprotein loci on Lp-PLA(2) levels, identified some novel null alleles in the PLA2G7 gene, and only identified one potentially efficacious subgroup within these two large clinical trials.

  • 1157822.
    Yeo, Jiho
    et al.
    Korea Advanced Institute of Science and Technology.
    Lee, Jooyoung
    Korea Advanced Institute of Science and Technology.
    Jang, Kitae
    Korea Advanced Institute of Science and Technology.
    Develop safety surrogate measure for evaluating motor carrier companies and drivers2018Conference paper (Refereed)
    Abstract [en]

    The risk of accidents of commercial vehicles is higher than that of ordinary vehicles. Traffic fatalities per registered vehicles are 3.8 times higher than in commercial vehicles than ordinary vehicles in 2016. Because of the high severity of accidents, there should be a lot of effort to reduce accidents and manage traffic safety of motor carrier companies. So far, safety assessments for commercial vehicles have been evaluated according to the frequency and the severity of accidents. This approach has several problems. First, the accident can not be preemptively prevented because it is based on the post evaluation of the accident. Second, it is difficult to provide consulting or action guidelines because it is impossible to determine what factors caused traffic accidents. With the recent development of data collection technology, not only traffic accident information, but also the various characteristics of motor carrier companies and drivers such as vehicle driving record, dangerous driving behavior, law violation information are collected. Therefore, this study aims to develop a new safety surrogate measure based on various characteristics of motor carrier companies and drivers.

  • 1157823. Yeo, Lay Hwee
    et al.
    Amer, Ramses
    Statsvetenskapliga institutionen, Umeå universitet.
    Caballero-Anthony, Mely
    Fjader, Christian
    Friberg, Erik
    Kivimaki, Timo
    Odgaard, Liselotte
    Packer, John
    Sukma, Rizal
    Tay, Simon S C
    Operationalising Preventive Diplomacy – Building Conflict Prevention Capacities in ASEAN and the ASEAN Regional Forum (ARF)2007Report (Other academic)
  • 1157824. Yeo, Leonard L L
    et al.
    Andersson, Tommy
    Yee, Kong Wan
    Tan, Benjamin Y Q
    Paliwal, Prakash
    Gopinathan, Anil
    Nadarajah, Mahendran
    Ting, Eric
    Teoh, Hock L
    Cherian, Robin
    Lundström, Erik
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Neurology.
    Tay, Edgar L W
    Sharma, Vijay K
    Synchronous cardiocerebral infarction in the era of endovascular therapy: which to treat first?2017In: Journal of Thrombosis and Thrombolysis, ISSN 0929-5305, E-ISSN 1573-742X, Vol. 44, no 1, p. 104-111Article in journal (Refereed)
    Abstract [en]

    A cardiocerebral ischemic attack (CCI) or a concurrent acute ischemic stroke (AIS) and myocardial infarction (AMI) is a severe event with no clear recommendations for ideal management because of the rarity of the scenario. The narrow time window for treatment and complexity of the treatment decision puts immense pressure on the treating physician. We evaluated this challenging situation at our tertiary center. Using our prospective stroke database out of a total of 555 patients with acute ischemic stroke between 2009 and 2014, we identified five consecutive cases with CCI (incidence 0.009%). Demography, risk factor characteristics, vascular occlusions and treatment approach were recorded. Good functional outcome was defined by the modified Rankin scale (mRS) score of 0-2 points. Out of five patients, AIS was treated with endovascular treatment in three cases, while two were treated with intravenous thrombolysis only. One out of three patients had embolectomy of the brain performed prior to the coronary intervention, while the other two patients underwent coronary intervention first. One patient developed sudden cardiac arrest on day-2 and passed away. CCI is an uncommon and devastating clinical scenario, further research is needed for the ideal management strategy that provides the best outcomes. However, the rarity of the disease does not lend itself to the conduct of a trial easily. We have proposed a considered treatment algorithm based on the current literature and our experience.

  • 1157825. Yeo, Leonard L L
    et al.
    Holmin, Staffan
    Andersson, Tommy
    Lundström, Erik
    Karolinska institutet, Solna, Sweden.
    Gopinathan, Anil
    Lim, Er Luen
    Leong, Benjamin S H
    Kuan, Win Sen
    Ting, Eric
    Tan, Benjamin Y Q
    Eide, Sterling Ellis
    Tay, Edgar L K
    Nongated Cardiac Computed Tomographic Angiograms for Detection of Embolic Sources in Acute Ischemic Stroke2017In: Stroke, ISSN 0039-2499, E-ISSN 1524-4628, Vol. 48, no 5, p. 1256-1261Article in journal (Refereed)
    Abstract [en]

    BACKGROUND AND PURPOSE: axis coverage of a non-ECG-gated computed tomographic angiogram performed in the primary evaluation of acute stroke without increasing the contrast dose.

    METHODS: Twenty consecutive patients with acute ischemic stroke within the 4.5 hours of symptom onset were prospectively recruited. We increased the longitudinal coverage to the domes of the diaphragm to include the heart. Contrast administration (Omnipaque 350) remained unchanged (injected at 3-4 mL/s; total 60-80 mL, triggered by bolus tracking). Images of the heart and aorta, reconstructed at 5 mm slice thickness in 3 orthogonal planes, were read by a radiologist and cardiologist, findings conveyed to the treating neurologist, and correlated with the transthoracic or transesophageal echocardiogram performed within the next 24 hours.

    RESULTS: Of 20 patients studied, 3 (15%) had abnormal findings: a left ventricular thrombus, a Stanford type A aortic dissection, and a thrombus of the left atrial appendage. Both thrombi were confirmed by transesophageal echocardiography, and anticoagulation was started urgently the following day. None of the patients developed contrast-induced nephropathy on follow-up. The radiation dose was slightly increased from a mean of 4.26 mSV (range, 3.88-4.70 mSV) to 5.17 (range, 3.95 to 6.25 mSV).

    CONCLUSIONS: Including the heart and ascending aorta in a routine non-ECG-gated computed tomographic angiogram enhances an existing imaging modality, with no increased incidence of contrast-induced nephropathy and minimal increase in radiation dose. This may help in the detection of high-risk cardiac and aortic sources of embolism in acute stroke patients.

  • 1157826. Yeo, L.H.
    et al.
    Zaslavsky, Arkady
    Simulation model for managing mobile workstations in distributed computing environment1994In: Meeting user needs: proceedings / Australian Telecommunication Networks & Applications Conference 1994, ATNAC, Melbourne, Australia, 5 - 7 December 1994, Monash University , 1994, p. 163-168Conference paper (Refereed)
  • 1157827.
    Yeo, L.H.
    et al.
    Monash University, Melbourne, VIC.
    Zaslavsky, Arkady
    Submission of transactions from mobile workstations in a cooperative multidatabase processing environment1994In: Proceedings of the 14th International Conference on Distributed Computing Systems: June 21 - 24, 1994, Poznan, Poland, Los Alamitos, Calif: IEEE Communications Society, 1994, p. 372-379Conference paper (Refereed)
    Abstract [en]

    In a multidatabase environment with mobile computers involved, the nature of computing is such that the user may not wait for the submitted global transaction to complete before disconnecting from the network. In this paper, a basic architectural framework to support transaction management in multidatabase systems is proposed and discussed. A simple message and queuing facility is suggested which provides a common communication and data exchange protocol to effectively manage global transactions submitted by mobile workstations (MWS). The state of global transactions is modelled through the use of transaction sub-queues. The proposed strategy allows an MWS to submit global transactions and then disconnect itself from the network to perform some other tasks, thereby increasing processing parallelism and independence

  • 1157828.
    Yeo, M.
    et al.
    Department of Food and Resource Economics, Korea University, Seoul, South Korea.
    Heshmati, Almas
    Department of Economics, Sogang University, Seoul, South Korea.
    Healthy Residential Environments for the Elderly2014In: Journal of Housing for the Elderly, ISSN 0276-3893, E-ISSN 1540-353X, Vol. 28, no 1, p. 1-20Article in journal (Refereed)
    Abstract [en]

    This study aims to analyze the environmental elements of residential facilities for elderly people by using Antonovsky’s salutogenic concept. The relationship between the environment and health is clearly identified. This information facilitates the presentation and development of residential facilities with healthy living conditions for elderly people in South Korea. The concept includes providing a residential environment that is safe from a variety of dangers by applying a barrier-free concept to address the physical changes of elderly people. It also provides an environment equipped with a continuous protection system that considers both the physical and sociopsychological aspects of this particular treatment environment. ©2014 Copyright Taylor & Francis Group, LLC.

  • 1157829.
    Yeo, Sara K.
    et al.
    University of Hawaii.
    Huggett, Megan J.
    University of Hawaii.
    Eiler, Alexander
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Limnology.
    Rappé, Michael S.
    University of Hawaii.
    Coastal Bacterioplankton Community Dynamics in Response to a Natural Disturbance2013In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 8, no 2, p. e56207-Article in journal (Refereed)
    Abstract [en]

    In order to characterize how disturbances to microbial communities are propagated over temporal and spatial scales in aquatic environments, the dynamics of bacterial assemblages throughout a subtropical coastal embayment were investigated via SSU rRNA gene analyses over an 8-month period, which encompassed a large storm event. During non-perturbed conditions, sampling sites clustered into three groups based on their microbial community composition: an offshore oceanic group, a freshwater group, and a distinct and persistent coastal group. Significant differences in measured environmental parameters or in the bacterial community due to the storm event were found only within the coastal cluster of sampling sites, and only at 5 of 12 locations; three of these sites showed a significant response in both environmental and bacterial community characteristics. These responses were most pronounced at sites close to the shoreline. During the storm event, otherwise common bacterioplankton community members such as marine Synechococcus sp. and members of the SAR11 clade of Alphaproteobacteria decreased in relative abundance in the affected coastal zone, whereas several lineages of GammaproteobacteriaBetaproteobacteria, and members of the Roseobacter clade of Alphaproteobacteria increased. The complex spatial patterns in both environmental conditions and microbial community structure related to freshwater runoff and wind convection during the perturbation event leads us to conclude that spatial heterogeneity was an important factor influencing both the dynamics and the resistance of the bacterioplankton communities to disturbances throughout this complex subtropical coastal system. This heterogeneity may play a role in facilitating a rapid rebound of regions harboring distinctly coastal bacterioplankton communities to their pre-disturbed taxonomic composition.

  • 1157830. Yeoh, Joseph G. C.
    et al.
    Pandit, Aniruddha A.
    Zandawala, Meet
    Stockholm University, Faculty of Science, Department of Zoology.
    Nässel, Dick R.
    Stockholm University, Faculty of Science, Department of Zoology.
    Davies, Shireen-Anne
    Dow, Julian A. T.
    DINeR: Database for Insect Neuropeptide Research2017In: Insect Biochemistry and Molecular Biology, ISSN 0965-1748, E-ISSN 1879-0240, Vol. 86, p. 9-19Article in journal (Refereed)
    Abstract [en]

    Neuropeptides are responsible for regulating a variety of functions, including development, metabolism, water and ion homeostasis, and as neuromodulators in circuits of the central nervous system. Numerous neuropeptides have been identified and characterized. However, both discovery and functional characterization of neuropeptides across the massive Class Insecta has been sporadic. To leverage advances in post-genomic technologies for this rapidly growing field, insect neuroendocrinology requires a consolidated, comprehensive and standardised resource for managing neuropeptide information. The Database for Insect Neuropeptide Research (DINeR) is a web-based database-application used for search and retrieval of neuropeptide information of various insect species detailing their isoform sequences, physiological functionality and images of their receptor-binding sites, in an intuitive, accessible and user-friendly format. The curated data includes representatives of 50 well described neuropeptide families from over 400 different insect species. Approximately 4700 FASTA formatted, neuropeptide isoform amino acid sequences and over 200 records of physiological functionality have been recorded based on published literature. Also available are images of neuropeptide receptor locations. In addition, the data include comprehensive summaries for each neuropeptide family, including their function, location, known functionality, as well as cladograms, sequence alignments and logos covering most insect orders. Moreover, we have adopted a standardised nomenclature to address inconsistent classification of neuropeptides. As part of the H2020 nEUROSTRESSPEP project, the data will be actively maintained and curated, ensuring a comprehensive and standardised resource for the scientific community. DINeR is publicly available at the project website: http://www.neurostresspep.eu/diner/.

  • 1157831. Yeoh, Phee
    et al.
    Elkashlan, Maged
    Duong, Quang Trung
    Blekinge Institute of Technology, School of Computing.
    Yang, Nan
    Da Costa, Daniel
    Transmit antenna selection in cognitive relay networks with Nakagami-m fading2013Conference paper (Refereed)
    Abstract [en]

    We examine the impact of multiple primary receivers on cognitive multiple-input multiple-output (MIMO) relay networks with underlay spectrum sharing. For such a network, we propose transmit antenna selection with receive maximal-ratio combining (TAS/MRC) as an interference-aware design to satisfy the power constraints in the primary and secondary networks. To demonstrate this, we derive new closed-form expressions for the exact and asymptotic outage probability with TAS/MRC and decode-and-forward (DF) relaying over independent Nakagami-m fading channels in the primary and secondary networks. Several important design insights are reached. We find that the TAS/MRC strategy achieves a full diversity gain when the transmit power in the secondary network is proportional to the peak interference power in the primary network. Furthermore, we highlight that the diversity-multiplexing tradeoff (DMT) of TAS/MRC is independent of the primary network and entirely dependent on the secondary network.

  • 1157832. Yeoh, Phee
    et al.
    Elkashlan, Maged
    Yang, Nan
    Benevides Da Costa, Daniel
    Duong, Quang Trung
    Blekinge Institute of Technology, School of Computing.
    MIMO multi-relay networks with TAS/MRC and TAS/SC in Weibull fading channels2012Conference paper (Refereed)
    Abstract [en]

    We examine transmit antenna selection with receiver maximal-ratio combining (TAS/MRC) and transmit antenna selection with receiver selection combining (TAS/SC) in multiple-input multiple-output (MIMO) relay networks. Amongst L two-hop relay links, a single relay offering the highest end-to-end signal-to-noise ratio (SNR) is activated. Assuming independent non-identically distributed Weibull fading between the hops, new closed-form asymptotic expressions for the outage probability and the symbol error rate are derived considering NS, NR, and ND antennas at the source, the relays, and the destination, respectively. Based on such expressions, the diversity order and the array gain for M-ary phase shift keying and M-ary quadrature amplitude modulation are analyzed. We highlight that the diversity order of TAS/MRC is the same as TAS/SC. As such, we explicitly characterize the SNR gap between TAS/MRC and TAS/SC as the ratio of their respective array gains. An interesting observation is reached that for equal per-hop SNRs, the SNR gap between the two protocols is independent of L.

  • 1157833. Yeoh, Phee Lep
    et al.
    Elkashlan, Maged
    Duong, Quang Trung
    Blekinge Institute of Technology, School of Computing.
    Yang, Nan
    Leung, Cyril
    Cognitive MIMO relaying in Nakagami-m fading2013Conference paper (Refereed)
    Abstract [en]

    We propose transmit antenna selection with receive maximal-ratio combining (TAS/MRC) as an effective approach to reduce interference in cognitive multiple-input multiple-output (MIMO) relay networks. To demonstrate this, we derive new closed-form expressions for the exact and asymptotic outage probability of TAS/MRC with multiple antennas at the primary and secondary users. We consider underlay spectrum sharing where the secondary users (SUs) transmit in the presence of multiple primary users (PUs). We consider independent Nakagami-m fading in both the primary and secondary networks. Several important design insights are revealed. We find that TAS/MRC achieves a full diversity when the transmit power at the SUs is proportional to the peak interference power at the PUs. Furthermore, we highlight that this diversity gain is completely independent of the number of antennas at the PUs.

  • 1157834. Yeoh, Phee Lep
    et al.
    Elkashlan, Maged
    Duong, Trung Q.
    Blekinge Institute of Technology, Faculty of Computing, Department of Communication Systems.
    Yang, Nan
    da Costa, Daniel Benevides
    Transmit Antenna Selection for Interference Management in Cognitive Relay Networks2014In: IEEE Transactions on Vehicular Technology, ISSN 0018-9545, E-ISSN 1939-9359, Vol. 63, no 7, p. 3250-3262Article in journal (Refereed)
    Abstract [en]

    We propose transmit antenna selection (TAS) in decode-and-forward (DF) relaying as an effective approach to reduce the interference in underlay spectrum sharing networks with multiple primary users (PUs) and multiple antennas at the secondary users (SUs). We compare two distinct protocols: 1) TAS with receiver maximal-ratio combining (TAS/MRC) and 2) TAS with receiver selection combining (TAS/SC). For each protocol, we derive new closed-form expressions for the exact and asymptotic outage probability with independent Nakagami-m fading in the primary and secondary networks. Our results are valid for two scenarios related to the maximum SU transmit power, i.e., P, and the peak PU interference temperature, i.e., Q. When P is proportional to Q, our results confirm that TAS/MRC and TAS/SC relaying achieve the same full diversity gain. As such, the signal-to-noise ratio (SNR) advantage of TAS/MRC relaying relative to TAS/SC relaying is characterized as a simple ratio of their respective SNR gains. When P is independent of Q, we find that an outage floor is obtained in the large P regime where the SU transmit power is constrained by a fixed value of Q. This outage floor is accurately characterized by our exact and asymptotic results.

  • 1157835. Yeoh, Phee Lep
    et al.
    Elkashlan, Maged
    Kim, Kyeong Jin
    Duong, Trung Quang
    Blekinge Institute of Technology, School of Computing.
    Karagiannidis, George K.
    Cognitive MIMO Relaying with Multiple Primary Transceivers2013In: 2013 IEEE GLOBAL COMMUNICATIONS CONFERENCE (GLOBECOM), 2013, p. 1956-1961Conference paper (Refereed)
    Abstract [en]

    We examine the impact of clusters of primary transceivers in cognitive multiple-input multiple-output (MIMO) relay networks with underlay spectrum sharing. In such a network, we propose antenna selection as an interference-aware design to satisfy the power constraints in the primary and secondary networks. To demonstrate this, we consider transmit antenna selection with maximal ratio combining (TAS/MRC) in the primary and secondary networks. With this in mind, we derive new closed-form asymptotic expressions for the outage probability and the symbol error rate (SER) over independent Nakagami-m fading channels. Our results lead to several new fundamental insights. In particular, we highlight that TAS/MRC achieves a full diversity gain when the maximum transmit power in the secondary network is proportional to the peak interference temperature in the primary network.

  • 1157836. Yeoh, Phee Lep
    et al.
    Elkashlan, Maged
    Yang, Nan
    da Costa, Daniel B.
    Duong, Quang Trung
    Blekinge Institute of Technology, School of Computing.
    Unified Analysis of Transmit Antenna Selection in MIMO Multi-Relay Networks2013In: IEEE Transactions on Vehicular Technology, ISSN 0018-9545, E-ISSN 1939-9359, Vol. 62, no 2Article in journal (Refereed)
    Abstract [en]

    We present a unified asymptotic framework for transmit antenna selection in multiple-input multiple-output (MIMO) multi-relay networks with Rician, Nakagami-m, Weibull, and Generalized-K fading channels. We apply this framework to derive new closed-form expressions for the outage probability and symbol error rate (SER) of amplify-andforward relaying in MIMO multi-relay networks with two distinct protocols: 1) transmit antenna selection with receiver maximalratio combining (TAS/MRC), and 2) transmit antenna selection with receiver selection combining (TAS/SC). Based on these expressions, the diversity order and the array gain with M-ary phase shift keying and M-ary quadrature amplitude modulation are derived.We corroborate that the diversity order only depends on the fading distribution and the number of diversity branches, whereas the array gain depends on the fading distribution, the modulation format, the number of diversity branches, and the average per-hop signal-to-noise ratios (SNRs). We highlight that the diversity order of TAS/MRC is the same as TAS/SC, regardless of the underlying fading distribution. As such, we explicitly characterize the SNR gap between TAS/MRC and TAS/SC as the ratio of their respective array gains. An interesting observation is reached that for equal per-hop SNRs, the SNR gap between the two protocols is independent of the number of relays.

  • 1157837. Yeoh, Phee Lep
    et al.
    Elkashlan, Maged
    Yang, Nan
    da Costa, Daniel
    Duong, Quang Trung
    Blekinge Institute of Technology, School of Computing.
    Unified Analysis of Transmit Antenna Selection in MIMO Multirelay Networks2013In: IEEE Transactions on Vehicular Technology, ISSN 0018-9545, E-ISSN 1939-9359, Vol. 62, no 2, p. 933-939Article in journal (Refereed)
    Abstract [en]

    We present a unified asymptotic framework for transmit antenna selection in multiple-input multiple-output (MIMO) multirelay networks with Rician, Nakagami-m, Weibull, and generalized-K fading channels. We apply this framework to derive new closed-form expressions for the outage probability and symbol error rate (SER) of amplify-and-forward (AF) relaying in MIMO multirelay networks with two distinct protocols: 1) transmit antenna selection with receiver maximal-ratio combining (TAS/MRC) and 2) transmit antenna selection with receiver selection combining (TAS/SC). Based on these expressions, the diversity order and the array gain with M-ary phase-shift keying and M-ary quadrature-amplitude modulation are derived. We corroborate that the diversity order only depends on the fading distribution and the number of diversity branches, whereas the array gain depends on the fading distribution, the modulation format, the number of diversity branches, and the average per-hop signal-to-noise ratios (SNRs). We highlight that the diversity order of TAS/MRC is the same as TAS/SC, regardless of the underlying fading distribution. As such, we explicitly characterize the SNR gap between TAS/MRC and TAS/SC as the ratio of their respective array gains. An interesting observation is reached that for equal per-hop SNRs, the SNR gap between the two protocols is independent of the number of relays.

  • 1157838. Yeom, H. W.
    et al.
    Horikoshi, K.
    Zhang, Hanmin
    Karlstad University, Faculty of Technology and Science, Department of Physics and Electrical Engineering.
    Ono, K.
    Uhrberg, R. I. G.
    Nature of the broken-symmetry phase of the one-dimensional metallic In/Si(111) surface2002In: Physical Review B. Condensed Matter and Materials Physics, ISSN 1098-0121, E-ISSN 1550-235X, Vol. 65, no 24Article in journal (Refereed)
  • 1157839.
    Yeom, H. W.
    et al.
    Atomic-scale Surface Science Research Center and Institute of Physics and Applied Physics, Yonsei University, bKorea.
    Horikoshi, K
    Department of Physics, The University of Tokyo, Japan.
    Zhang, Hanmin
    Linköping University, Department of Physics, Chemistry and Biology. Linköping University, The Institute of Technology.
    Ono, K
    Department of Applied Chemistry, The University of Tokyo, Japan .
    Uhrberg, Roger
    Linköping University, Department of Physics, Chemistry and Biology, Surface and Semiconductor Physics. Linköping University, The Institute of Technology.
    Nature of the broken-symmetry phase of the one-dimensional metallic In/Si(111) surface2002In: Physical Review B. Condensed Matter and Materials Physics, ISSN 1098-0121, E-ISSN 1550-235X, Vol. 65, no 24Article in journal (Refereed)
    Abstract [en]

    The phase transition of a metallic In chain structure on Si(111) was investigated by high-resolution photoemission. Core-level spectra clearly elucidate that the symmetry breaking at low temperature occurs only within the inner parts of the In chains. In the valence bands, the transition is accompanied by the formation of pseudogaps of 80–150 meV and the band backfolding with only marginal changes of the band dispersion. No sign of Luttinger liquid behavior is observed in the spectral function near the Fermi level. This result is generally consistent with the idea of a fluctuating one-dimensional charge-density wave state but conflicting with the present structure model for the low-temperature phase.

  • 1157840.
    Yeom, HW
    et al.
    Department of Applied Chemistry, University of Tokyo, Japan.
    Matsuda, I
    Department of Chemistry, University of Tokyo, Japan.
    Chao, Y.-C.
    Linköping University, Department of Physics, Chemistry and Biology. Linköping University, The Institute of Technology.
    Hara, S
    Electrotechnical Laboratory, Tsukuba, Japan.
    Yoshida, S
    Electrotechnical Laboratory, Tsukuba, Japan.
    Uhrberg, Roger
    Linköping University, Department of Physics, Chemistry and Biology, Surface and Semiconductor Physics. Linköping University, The Institute of Technology.
    Hydrogen-induced 3×1 phase of the Si-rich 3C-SiC(001) surface2000In: Physical Review B. Condensed Matter and Materials Physics, ISSN 1098-0121, E-ISSN 1550-235X, Vol. 61, no 4, p. R2417-R2420Article in journal (Refereed)
    Abstract [en]

    A single-domain 3×1 phase induced by hydrogen adsorption on a Si-rich 3C-SiC(001)3×2 surface is investigated by photoemission using synchrotron radiation. Three surface components of the Si 2p core level are identified for the 3×1-H phase, which resemble those of the 3×2 surface. A H-Si bonding state is observed by angle-resolved valence-band photoemission. These results are consistent with the recent assignments of the Si 2p surface components and the valence band spectra of the 3×2 surface, based on the 3×2 structure model with 2/3 ML Si addimers. A straightforward 3×1-H structure model is introduced featuring Si dimer-bond breaking and dangling-bond saturation.

  • 1157841.
    Yeom, HW
    et al.
    Yonsei Univ, Atom Scale Surface Sci Res Ctr, Seoul 120749, South Korea Yonsei Univ, Inst Phys & Appl Phys, Seoul 120749, South Korea Linkoping Univ, Dept Phys & Measurement Technol, S-58183 Linkoping, Sweden.
    Uhrberg, Roger
    Linköping University, The Institute of Technology. Linköping University, Department of Physics, Chemistry and Biology, Surface and Semiconductor Physics .
    High resolution photoemission study of low-temperature oxidation on the Si(001) surface2000In: Japanese Journal of Applied Physics, ISSN 0021-4922, E-ISSN 1347-4065, Vol. 39, no 7B, p. 4460-4463Article in journal (Refereed)
    Abstract [en]

    High-resolution photoemission is applied to the oxygen adsorption on the Si(001) surface at 120 K and the subsequent evolution of the adsorbates upon annealing. Si 2p components due to the Si2+ and Si3+ species are observed from the very early stage of adsorption at similar to 120 K, which grow linearly with the oxygen coverage. This indicates an active agglomeration of oxygen adsorbates even for the submonolayer adsorption at low temperature. Annealing above 500 K enhances the agglomeration by mostly converting the Si1+ species into Si3+ and then into Si4+. In addition, the annealing changes the Si 2p binding energies for the Si2+ and Si3+ species by 0.14 and 0.23 eV, respectively. These shifts are attributed to the structural relaxation (strain relief) of the metastable oxygen-adsorbate complex formed at low temperature.

  • 1157842.
    Yeom, Kee Yoon
    Umeå University, Faculty of Social Sciences, Department of applied educational science.
    Idrott och hälsa i gymnasiet med fokus ur ett hälsoperspektiv och idrottspraktiker2015Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    En djupare insikt i elevernas förkunskaper inom hälsa och träningspraktiker bör kunna underlätta för lärare att planera och genomföra undervisningen, samt att genom denna kunskap enklare kunna motivera sina elever att utvecklas i ämnet idrott och hälsa. Syftet var att undersöka och analysera idrottsundervisningen i ämnet idrott och hälsa på gymnasiet med fokus ur elevers hälsoperspektiv och vilken idrottspraktik de inriktat sig på. För att undersöka detta användes både en kvantitativ och en kvalitativ metoddel i form av en enkät, samt en portfoliouppgift som delades ut till elever i årskurs tre på gymnasiet. Urvalet utgjordes av 100 elever i den kvantitativa delen, och 20 elever fördelat på 10 tjejer och 10 killar i den kvalitativa delen. Utifrån denna studie så har det tydligt uppkommit ett kvantifierbart underlag, där tre av de sju idrottspraktikerna fanns representerade. En hel del skillnader fanns mellan tjejerna och killarna men överlag var de samstämmiga i sina reflektioner i den kvalitativa delen. Där de flesta ansåg att det fria valet ökade motivationen till att prestera under lektionerna i ämnet idrott och hälsa. För att nå detta krävdes det enligt eleverna att lärarna var mer lyhörda till elevernas önskemål. Därmed bör man med hjälp av en djupare insikt i de idrottspraktiker som finns representerade hos eleverna kunna bygga upp en mer varierad och anpassad studieplan, som direkt går att knyta till läroplanen för idrott och hälsa.

  • 1157843.
    Yeomans, N
    et al.
    Univ Melbourne, Western Hosp, Dept Med, Footscray, Vic 3011, Australia AstraZeneca R&D Molndal, Molndal, Sweden Univ Nottingham Hosp, Div Gastroenterol, Nottingham NG7 2UH, England Linkoping Univ, Dept Biomed & Surg, S-58183 Linkoping, Sweden Linkoping Univ, Dept Internal Med, S-58183 Linkoping, Sweden Univ Bergen, Dept Publ Hlth & Primary Hlth Care, N-5020 Bergen, Norway.
    Wilson, I
    Univ Melbourne, Western Hosp, Dept Med, Footscray, Vic 3011, Australia AstraZeneca R&D Molndal, Molndal, Sweden Univ Nottingham Hosp, Div Gastroenterol, Nottingham NG7 2UH, England Linkoping Univ, Dept Biomed & Surg, S-58183 Linkoping, Sweden Linkoping Univ, Dept Internal Med, S-58183 Linkoping, Sweden Univ Bergen, Dept Publ Hlth & Primary Hlth Care, N-5020 Bergen, Norway.
    Langstrom, G
    Univ Melbourne, Western Hosp, Dept Med, Footscray, Vic 3011, Australia AstraZeneca R&D Molndal, Molndal, Sweden Univ Nottingham Hosp, Div Gastroenterol, Nottingham NG7 2UH, England Linkoping Univ, Dept Biomed & Surg, S-58183 Linkoping, Sweden Linkoping Univ, Dept Internal Med, S-58183 Linkoping, Sweden Univ Bergen, Dept Publ Hlth & Primary Hlth Care, N-5020 Bergen, Norway.
    Hawkey, C
    Univ Melbourne, Western Hosp, Dept Med, Footscray, Vic 3011, Australia AstraZeneca R&D Molndal, Molndal, Sweden Univ Nottingham Hosp, Div Gastroenterol, Nottingham NG7 2UH, England Linkoping Univ, Dept Biomed & Surg, S-58183 Linkoping, Sweden Linkoping Univ, Dept Internal Med, S-58183 Linkoping, Sweden Univ Bergen, Dept Publ Hlth & Primary Hlth Care, N-5020 Bergen, Norway.
    Naesdal, J
    Univ Melbourne, Western Hosp, Dept Med, Footscray, Vic 3011, Australia AstraZeneca R&D Molndal, Molndal, Sweden Univ Nottingham Hosp, Div Gastroenterol, Nottingham NG7 2UH, England Linkoping Univ, Dept Biomed & Surg, S-58183 Linkoping, Sweden Linkoping Univ, Dept Internal Med, S-58183 Linkoping, Sweden Univ Bergen, Dept Publ Hlth & Primary Hlth Care, N-5020 Bergen, Norway.
    Walan, A
    Wiklund, I
    Quality of life in chronic NSAID users: a comparison of the effect of omeprazole and misoprostol2001In: Scandinavian Journal of Rheumatology, ISSN 0300-9742, E-ISSN 1502-7732, Vol. 30, no 6, p. 328-334Article in journal (Refereed)
    Abstract [en]

    Objective: To compare the impact on quality of life (QoL) of omeprazole and misoprostol during healing, and omeprazole, misoprostol, and placebo during maintenance treatment in chronic NSAID users with NSAID-associated gastroduodenal lesions. Methods: Validated baseline and follow-up QoL questionnaires were completed by 610 patients (healing: after 4.8 weeks: maintenance: after 6 months). Results: Patients with arthritis being treated with NSAIDs have a poor QoL. Rheumatoid arthritis causes more joint problem. and physical mobility limitations than osteoarthritis. Chronic NSAID use causes heartburn and dyspepsia. QoL improved on both treatments (about equally on two general QOL scales), but omeprazole relieved gastrointestinal symptoms more than misoprostol, particularly reflux. abdominal pain and indigestion symptoms, During maintenance, both treatments maintained QoL, but misoprostol induced diarrhoea, Conclusion: QoL in arthritis patient, on chronic NSAID treatment is destroyed. Omeprazole is superior to misoprostol for relief and prevention of NSAID-associated gastrointestinal symptoms allowing continued NSAID treatment without compromising the patients' QoL.

  • 1157844. Yeow, Paul
    et al.
    Yuen, Yee Yen
    Tong, David Yoon Kin
    Lim, Nena
    Örebro University, Swedish Business School at Örebro University.
    User acceptance of online banking service in Australia2008In: 10th International Business Information Management (IBIMA) Conference on Innovation and Knowledge Management in Business Globalization, 2008, p. 129-135Conference paper (Refereed)
  • 1157845. Yep, Ray
    Negotiating Autonomy in Greater China: Hong Kong and its Sovereign Before and After 19972013Collection (editor) (Refereed)
    Abstract [en]

    Local autonomy is a complex and often contentious issue in many countries, not least because the situation often involves a process of continuous (re)negotiation. Moreover, the actual power relationship is defined not only by legal permissibility but also by such other factors as varying political perceptions, economic interests and previous encounters between the centre and periphery.

    This volume demonstrates that Hong Kong is a good illustration of the intricacies of the dynamic relationship in a Chinese context. The territory has a long history of pursuing its own path, both in colonial times and since 1997. With essays spanning both periods, the volume offers an understanding of the mind-set and actions of both Beijing and Hong Kong in pursuing their goals. It also provides a nuanced framework for evaluating central–local interaction in general.

  • 1157846.
    Yepes-Baldó, Montserrat
    et al.
    Universitat de Barcelona.
    Romeo, Marina
    Universitat de Barcelona.
    Westerberg, Kristina
    Umeå University, Faculty of Social Sciences, Department of Psychology.
    Nordin, Maria
    Umeå University, Faculty of Social Sciences, Department of Psychology.
    Job crafting, employee well-being, and quality of care2018In: Western Journal of Nursing Research, ISSN 0193-9459, E-ISSN 1552-8456, Vol. 40, no 1, p. 52-66Article in journal (Refereed)
    Abstract [en]

    The main objective is to study the effects of job crafting activities of elder care and nursing home employees on their perceived well-being and quality of care in two European countries, Spain and Sweden. The Job Crafting, the General Health, and the Quality of Care questionnaires were administered to 530 employees. Correlations and hierarchical regression analyses were performed. Results confirm the effects of job crafting on quality of care (r = .291, p < .01; β = .261, p < .01; ΔR2 = .065, p < .01) and employees’ well-being (r = .201, p < .01; β = .171, p < .01; ΔR2 = .028, p < .01). A positive linear relationship was found between job crafting and well-being in Spain and Sweden and with quality of care in Spain. On the contrary, in Sweden, the relationship between job crafting and well-being was not linear. Job crafting contributes significantly to employees’ and residents’ well-being. Management should promote job crafting to co-create meaningful and productive work. Cultural effects are proposed to explain the differences found.

  • 1157847.
    Yeqiang, Lin
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Information Systems and Technology.
    Visualizing large-scale and high-dimensional time series data2017Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    Time series is one of the main research objects in the field of data mining.

    Visualization is an important mechanism to present processed time series for further

    analysis by users. In recent years researchers have designed a number of

    sophisticated visualization techniques for time series. However, most of these

    techniques focus on the static format, trying to encode the maximal amount of

    information through one image or plot. We propose the pixel video technique, a

    visualization technique displaying data in video format. Using pixel video technique,

    a hierarchal dimension cluster tree for generating the similarity order of

    dimensions is first constructed, each frame image is generated according to pixeloriented

    techniques displaying the data in the form of a video.

  • 1157848.
    Yera, Daniel
    et al.
    Halmstad University, School of Business, Engineering and Science.
    Pichou, Alexandra
    Halmstad University, School of Business, Engineering and Science.
    Sports Marketing in European Clubs2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Sports marketing have been growing constantly over the last years and have become a key for the success of the football clubs. The methods used have become more sophisticated and an increasing number of clubs are realizing the importance of the marketing and specially the promotion strategies. The purpose of this study is to have a better understanding on how the communication strategies are being used in the European football teams (French, Spanish and German) to attract fans to their stadiums. In order to reach this purpose, research question is focused on how the European teams use this promotion strategies to attract people to the stadium. Based on this research question, a review of relevant literature was conducted, resulting in a frame of references, which was used to guide this study's data collection. A qualitative, multiple case study approach was used to find the data. The findings indicate that although his individual objectives of the tools can be different they can still be used overall to lead to the same overall goal.

  • 1157849.
    Yeranossian, Tzovinar
    Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Sociology.
    Changing Countries, Changing Cultures: A Qualitative Study of Cultural Change After Migration2017Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    In a time of globalization and multiculturalism, the discourses on migration and social issues have become increasingly focused on culture. Although cultural changes are considered an important part of integration processes, there is uncertainty about what these changes actually are, and how they come about. The purpose of this study is to examine how migrants define and experience culture and cultural changes, and how they construct these changes. Starting from an elaborated version of Ann Swidler’s concept of culture as a toolkit, and through interviews with 19 people who have migrated to Sweden, the study shows that people experience culture as permeating all aspects of their life, intimately linked to their social lives. They also actively use culture as a tool to negotiate between cultural preservation, and integration into a new society. In the process of cultural changes, culture is both the subject of change, and the method for their construction.

  • 1157850.
    Yeranossian, Tzovinar
    Linnaeus University, Faculty of Humanities and Social Sciences, School of Social Sciences. Linnaeus University, Faculty of Humanities and Social Sciences, School of Cultural Sciences.
    Integration från ord till handling: En undersökning av integrationens betydelser inom sociologi, politik och praktiskt arbete2012Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    This study deals with the concept of ’integration’. Starting from the concept of reality as socially and linguistically constructed, it is an attempt to see how lingual constructions and perceptions affect the official structures of society and vice versa. The main purpose is to compare the different meanings integration has in a sociological context and in a political one. Further, the purpose is to see how the relationship between the sociological and political concepts affects the integrational work in the Swedish County Administrative Boards, and which consequences these effects might have. The study is carried out with ethnographic methods, i.e. participant observation and textual analysis, in a specific County Administrative Board, focusing mainly on its policy and strategy for integrational work. The results are that the main differences between the sociological and political definitions of integration lie in their extent of meanings. The sociological definitions contain many different meanings which sometimes contradict each other. The political ones however are more fixed and limited in their scope. The goal of the integrational politics is not always clear and this affects the practical work. Other problems are that the political as well as practical integrational definitions are limited to certain groups during certain conditions. The consequences of these problems can be that certain groups are left out of the integrational process, that some of the factors of integration are neglected and that immigrants, being the designated group in need of integration, are stigmatized.

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