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  • 1.
    Bjällmark, Anna
    et al.
    KTH, Skolan för teknik och hälsa (STH), Medicinsk teknik.
    Gustafsson, U
    Brodin, Lars-Åke
    KTH, Skolan för teknik och hälsa (STH), Medicinsk teknik.
    Waldenström, A
    Larsson, Matilda
    KTH, Skolan för teknik och hälsa (STH), Medicinsk teknik.
    A system to quantify and visualize ventricular rotation pattern of the heart2009Patent (Annet (populærvitenskap, debatt, mm))
    Abstract [en]

    Different modalities have been used to describe the rotational motion of the ventricles of the heart and studies have indicated LV twist to be an additional integral component in LV function. So far, only amplitudes and timings of rotation have been reported, whereas no method is available to fully describe the rotation pattern of the ventricles. The object of the present application is to achieve a system that presents a novel way to quantify and visualize the ventricular rotation pattern of the heart. We present a novel method that assesses and describes the rotation pattern by calculating the rotation axis of the ventricle. Non- invasive image acquisition is required to collect rotation values from different positions of the myocardium. Thereafter, a kinematic model of a ventricle is constructed to determine the rotation planes at different levels of the heart. The motion of the rotation planes are visualized by plotting the normal vectors of the planes over time, i.e. the rotation axis of the planes. This new method is different to all other methods used today for assessing cardiac function, as it does not describe the amplitude of a motion but the relationship in motion between different parts within a ventricle. Preliminary results indicate that the rotation axis is more sensitive to changes in the rotation pattern than conventional measurements of ventricular rotation. This new method could be used for early detection of cardiac diseases and for selection of patients for and optimization of cardiac resynchronization therapy.

  • 2.
    Brodin, Lars-Åke
    et al.
    KTH, Skolan för teknik och hälsa (STH), Medicinsk teknik.
    Elmqvist, H
    Bjällmark, Anna
    KTH, Skolan för teknik och hälsa (STH), Medicinsk teknik.
    Larsson, Matilda
    KTH, Skolan för teknik och hälsa (STH), Medicinsk teknik.
    Global and local detection of blood vessel elasticity2006Patent (Annet (populærvitenskap, debatt, mm))
    Abstract [en]

    The present invention is a non-invasive analysis system for detection of global and local blood vessel elasticity. The analysis system comprises two subsystems where subsystem 1 is data collecting unit and subsystem 2 is an analysis unit. The data collecting unit comprises one or many non-invasive image generating systems, or the data collecting system makes the registration possible of movement parameters that quantifies the dynamics of the blood vessel wall in longitudinal and radial directions. Subsystem 2 performs Wave Intensity Analysis which is an analysis method using co-related parts of the circulation system by measuring the intensity change (dl) of the blood vessel during a heart cycle. The intensity change is calculated as the product of the pressure derivate and the flow velocity derivate. In subsystem 2 the changes of pressure and flow are approximated by the deformation velocity or velocity of the radial and longitudinal direction, respectively. By calculating time constants and amplitudes of the intensity change graph a measure is obtained of the local and global elasticity of the blood vessel and atherosclerotic constrictions of arterial vessels may then be identified at an early stage.

  • 3.
    von Holst, Hans
    et al.
    KTH, Skolan för teknik och hälsa (STH), Neuronik.
    Kleiven, Svein
    KTH, Skolan för teknik och hälsa (STH), Neuronik.
    Protective Material2010Patent (Annet (populærvitenskap, debatt, mm))
    Abstract [en]

    A protective material/structure is provided that reduces the risk of injury for a person after contact with said material/structure, and is based on a structure where an inner and outer shell can move relative to each other. The shells are separated by spikes or thin beams and the outer shell covers or envelops the spikes. The spikes or beams are constructed so that they permit displacement of the outer shell relative to the inner shell in the event of an oblique impact against the protective material/structure. The spikes or beams are designed to be thin/slim and can be made of flexible polymer materials such as plastics, rubber or fibers. This enables the spikes to give way after a tangential/rotational impact and thereby efficiently reduce the negative effects of such an impact on the brain. The material/structure can be used in e.g. helmets, vehicle interiors, vehicle exteriors, indoor house building material, boxing gloves and the like.

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