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  • 1.
    Elmstedt, Nina
    et al.
    KTH, School of Technology and Health (STH), Medical Engineering.
    Lind, Britta
    KTH, School of Technology and Health (STH), Medical Engineering.
    Ferm-Widlund, K.
    Westgren, M.
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering.
    Fetal heart contractile function and gestational age2012In: Cardiovascular Research, ISSN 0008-6363, E-ISSN 1755-3245, Vol. 93, p. S108-S108Article in journal (Other academic)
  • 2.
    Erlandsson, Björn-Erik
    et al.
    KTH, School of Technology and Health (STH), Health Systems Engineering, Systems Safety and Management.
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering.
    Medicinsk säkerhet2016In: Anestesi / [ed] Sten GE Lindahl, Ola Winsö, Jonas Åkeson, Stockholm: Liber AB , 2016, 3, p. 168-173Chapter in book (Other academic)
  • 3. Govindan, Malini
    et al.
    Kiotsekoglou, Anatoli
    Batchvarov, Velislav
    Saha, Samir K.
    Dougal, Kate
    Teoh, Evaun
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering.
    Camm, John
    LEFT ATRIAL EXPANSION INDEX IN PATIENTS WITH ATRIAL FIBRILLATION IS A PREDICTOR OF SINUS RHYTHM MAINTENANCE AFTER CARDIOVERSION2010In: Journal of the American College of Cardiology, ISSN 0735-1097, E-ISSN 1558-3597, Vol. 55, no 10Article in journal (Other academic)
  • 4.
    Kothapalli, Satya V.V.N.
    et al.
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.
    Wiklund, Martin
    KTH, School of Engineering Sciences (SCI), Applied Physics, Cell Physics.
    Janerot Sjöberg, Birgitta
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging. Karolinska Institutet, Sweden; Karolinska University Hospital, Sweden .
    Paradossi, Gaio
    Diapartimento di Chimica, Università di Roma Tor Vergata.
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.
    Grishenkov, Dmitry
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging. Karolinska Institutet, Sweden; Karolinska University Hospital, Sweden .
    Investigation of Polymer-Shelled Microbubble Motions in AcoustophoresisManuscript (preprint) (Other academic)
    Abstract [en]

    The objective of this paper is to explore the trajectory motion of microsize (typically smaller than a redblood cell) encapsulated polymer-shelled gas bubbles propelled by radiation force in an acousticstanding-wave field and to compare the corresponding movements of solid polymer microbeads. Theexperimental setup consists of a microfluidic chip coupled to a piezoelectric crystal (PZT) with aresonance frequency of about 2.8 MHz. The microfluidic channel consists of a rectangular chamberwith a width, w, corresponding to one wavelength of the ultrasound standing wave. It creates one fullwave ultrasound of a standing-wave pattern with two pressure nodes at4w and43w and threeantinodes at 0,2w , and w. The peak-to-peak amplitude of the electrical potential over the PZT wasvaried between 1 and 10 volts. From Gor’kov’s potential equation, the acoustic contrast factor, Φ, forthe polymer-shelled microbubbles was calculated to about -60.7. Experimental results demonstratethat the polymer-shelled microbubbles are translated and accumulated at the pressure antinode planes.This trajectory motion of polymer-shelled microbubbles toward the pressure antinode plane is similarto what has been described for other acoustic contrast particles with a negative Φ. First, primaryradiation forces dragged the polymer-shelled microbubbles into proximity with each other at thepressure antinode planes. Then, secondary radiation forces caused them to aggregate at different spotsalong the channel. The relocation time for polymer-shelled microbubbles was 40 times shorter thanthat for polymer microbeads, and in contrast to polymer microbeads, the polymer-shelledmicrobubbles were actuated even at driving voltages (proportional to radiation forces) as low as 1 volt.In short, the polymer-shelled microbubbles demonstrate the behavior attributed to the negativeacoustic contrast factor particles and thus can be trapped at the antinode plane and thereby seperatedfrom solid particles, such as cells. This phenomenon could be utilized in exploring future applications,such as bioassay, bioaffinity, and cell interaction studies in vitro in a well-controlled environment.

  • 5.
    Kothapalli, Veeravenkata S.
    et al.
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.
    Oddo, L.
    Paradossi, G.
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.
    Grishenkov, Dmitry
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.
    Assessment of the viscoelastic and oscillation properties of a nanoengineered-shelled multimodality contrast agentManuscript (preprint) (Other academic)
  • 6.
    Kronander, Håkan
    et al.
    KTH, School of Technology and Health (STH), Medical Engineering.
    Fischer-Colbrie, W
    Hammar, N.
    Nowak, J.
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering.
    Elmqvist, Håkan
    Analysis of ST/HR hysterisis improves long-term prognostic value of exercise ECG test.Manuscript (preprint) (Other academic)
  • 7.
    Larsson, Malin
    et al.
    KTH, School of Technology and Health (STH), Medical Engineering.
    Bjällmark, Anna
    KTH, School of Technology and Health (STH), Medical Engineering.
    Larsson, Matilda
    KTH, School of Technology and Health (STH), Medical Engineering.
    Caidahl, Kenneth
    Winter, Reidar
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering.
    A novel technique to visualize target specific polymeric contrast agents2011Conference paper (Other academic)
  • 8.
    Manouras, Aristomenis
    et al.
    KTH, School of Technology and Health (STH), Medical Engineering.
    Nyktari, Evangelia
    Sahlén, Anders
    Winter, Reidar
    Vardas, Panagiotis
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering.
    The value of E/Em ratio in the estimation of left ventricular filling pressures: impact of acute hemodynamic load reductionManuscript (preprint) (Other academic)
  • 9. Sahlen, A.
    et al.
    Abdula, G.
    Norman, M.
    Manouras, Aristomenis
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.
    Lund, L. H.
    Shahgaldi, Kambiz
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.
    Winter, Reidar
    KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.
    Altered arterial haemodynamics during exercise in elderly female hypertensives with poor stroke volume reserve2011In: European Heart Journal, ISSN 0195-668X, E-ISSN 1522-9645, Vol. 32, p. 10-11Article in journal (Other academic)
  • 10. Shahgaldi, K.
    et al.
    Söderqvist, E.
    Ostenfeld, E.
    Winter, R.
    Nowak, J.
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering.
    Flow-volume loops from three-dimensional echocardiography: A novel technique for assessment of left ventricular function and hemodynamics2006In: Journal of the American College of Cardiology, ISSN 0735-1097, E-ISSN 1558-3597, Vol. 47, no 4, p. 141A-141AArticle in journal (Other academic)
  • 11. Winter, R.
    et al.
    Mobasseri, Y.
    Nowak, J.
    Saha, S.
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering.
    Colour-coded tissue tracking is an accurate, fast, and simple tool for identification of non-ischemic patients in the hand of inexperienced stress echocardiography reader2006In: Journal of the American College of Cardiology, ISSN 0735-1097, E-ISSN 1558-3597, Vol. 47, no 4, p. 124A-124AArticle in journal (Other academic)
  • 12. Wågström, Elle
    et al.
    Johnson, Jonas
    KTH, School of Technology and Health (STH), Medical Engineering.
    Ferm-Widlund, Kjerstin
    Elmstedt, Nina
    KTH, School of Technology and Health (STH), Medical Engineering.
    Liuba, Karina
    Lind, Britta
    KTH, School of Technology and Health (STH), Medical Engineering.
    Brodin, Lars-Åke
    KTH, School of Technology and Health (STH), Medical Engineering.
    Westgren, Magnus
    The Cardiac State Diagram as a novel approach for evaluation of phases of the cardiac cycle in asfyxiated fetal lambs2012In: Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, E-ISSN 1600-0412, Vol. 91, p. 144-144Article in journal (Other academic)
1 - 12 of 12
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