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  • 251.
    Aronsson, Christopher
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär fysik. Linköpings universitet, Tekniska fakulteten.
    Tunable and modular assembly of polypeptides and polypeptide-hybrid biomaterials2016Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [en]

    Biomaterials are materials that are specifically designed to be in contact with biological systems and have for a long time been used in medicine. Examples of biomaterials range from sophisticated prostheses used for replacing outworn body parts to ordinary contact lenses. Currently it is possible to create biomaterials that can e.g. specifically interact with cells or respond to certain stimuli. Peptides, the shorter version of proteins, are excellent molecules for fabrication of such biomaterials. By following and developing design rules it is possible to obtain peptides that can self-assemble into well-defined nanostructures and biomaterials.

    The aim of this thesis is to create ”smart” and tunable biomaterials by molecular self-assembly using dimerizing –helical polypeptides. Two different, but structurally related, polypeptide-systems have been used in this thesis. The EKIV-polypeptide system was developed in this thesis and consists of four 28-residue polypeptides that can be mixed-and-matched to self-assemble into four different coiled coil heterodimers. The dissociation constant of the different heterodimers range from μM to < nM. Due to the large difference in affinities, the polypeptides are prone to thermodynamic social self-sorting. The JR-polypeptide system, on the other hand, consists of several 42-residue de novo designed helix-loop-helix polypeptides that can dimerize into four-helix bundles. In this work, primarily the glutamic acid-rich polypeptide JR2E has been explored as a component in supramolecular materials. Dimerization was induced by exposing the polypeptide to either Zn2+, acidic conditions or the complementary polypeptide JR2K.

    By conjugating JR2E to hyaluronic acid and the EKIV-polypeptides to star-shaped poly(ethylene glycol), respectively, highly tunable hydrogels that can be self-assembled in a modular fashion have been created. In addition, self-assembly of spherical superstructures has been investigated and were obtained by linking two thiol-modified JR2E polypeptides via a disulfide bridge in the loop region. ŒThe thesis also demonstrates that the polypeptides and the polypeptide-hybrids can be used for encapsulation and release of molecules and nanoparticles. In addition, some of the hydrogels have been explored for 3D cell culture. By using supramolecular interactions combined with bio-orthogonal covalent crosslinking reactions, hydrogels were obtained that enabled facile encapsulation of cells that retained high viability.

    The results of the work presented in this thesis show that dimerizing α–helical polypeptides can be used to create modular biomaterials with properties that can be tuned by specific molecular interactions. The modularity and the tunable properties of these smart biomaterials are conceptually very interesting andmake them useful in many emerging biomedical applications, such as 3D cell culture, cell therapy, and drug delivery

    .

  • 252.
    Aronsson, Christopher
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär fysik. Linköpings universitet, Tekniska fakulteten.
    Dånmark, Staffan
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär fysik. Linköpings universitet, Tekniska fakulteten.
    Zhou, Feng
    Nanyang Technology University, Singapore.
    Öberg, Per
    Linköpings universitet, Institutionen för systemteknik, Fordonssystem. Linköpings universitet, Tekniska högskolan.
    Enander, Karin
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär fysik. Linköpings universitet, Tekniska fakulteten.
    Su, Haibin
    Nanyang Technology University, Singapore.
    Aili, Daniel
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär fysik. Linköpings universitet, Tekniska fakulteten.
    Self-sorting heterodimeric coiled coil peptides with defined and tuneable self-assembly properties2015Ingår i: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 5, nr 14063Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Coiled coils with defined assembly properties and dissociation constants are highly attractive components in synthetic biology and for fabrication of peptide-based hybrid nanomaterials and nanostructures. Complex assemblies based on multiple different peptides typically require orthogonal peptides obtained by negative design. Negative design does not necessarily exclude formation of undesired species and may eventually compromise the stability of the desired coiled coils. This work describe a set of four promiscuous 28-residue de novo designed peptides that heterodimerize and fold into parallel coiled coils. The peptides are non-orthogonal and can form four different heterodimers albeit with large differences in affinities. The peptides display dissociation constants for dimerization spanning from the micromolar to the picomolar range. The significant differences in affinities for dimerization make the peptides prone to thermodynamic social self-sorting as shown by thermal unfolding and fluorescence experiments, and confirmed by simulations. The peptides self-sort with high fidelity to form the two coiled coils with the highest and lowest affinities for heterodimerization. The possibility to exploit self-sorting of mutually complementary peptides could hence be a viable approach to guide the assembly of higher order architectures and a powerful strategy for fabrication of dynamic and tuneable nanostructured materials.

  • 253.
    Aronsson, Christopher
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär fysik. Linköpings universitet, Tekniska fakulteten.
    Selegård, Robert
    Linköpings universitet, Institutionen för fysik, kemi och biologi. Linköpings universitet, Tekniska fakulteten.
    Aili, Daniel
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär fysik. Linköpings universitet, Tekniska fakulteten.
    Zinc-Triggered Hierarchical Self-Assembly of Fibrous Helix-Loop-Helix Peptide Superstructures for Controlled Encapsulation and Release2016Ingår i: Macromolecules, ISSN 0024-9297, E-ISSN 1520-5835, Vol. 49, nr 18, 6997-7003 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    We demonstrate a novel route for hierarchical self-assembly of sub-micrometer-sized peptide superstructures that respond to subtle changes in Zn2+ concentration. The self-assembly process is triggered by a specific folding-dependent coordination of Zn2+ by a de novo designed nonlinear helix-loop-helix peptide, resulting in a propagating fiber formation and formation of spherical superstructures. The superstructures further form larger assemblies that can be completely disassembled upon removal of Zn2+ or degradation of the nonlinear peptide. This flexible and reversible assembly strategy of the superstructures enables facile encapsulation of nanoparticles and drugs that can be released by means of different stimuli.

  • 254.
    Arshad, Sana
    et al.
    NED University of Engn and Technology, Pakistan.
    Ramzan, Rashad.
    United Arab Emirates University, U Arab Emirates.
    Zafar, Faiza
    NED University of Engn and Technology, Pakistan.
    Wahab, Qamar-Ul
    Linköpings universitet, Institutionen för fysik, kemi och biologi. Linköpings universitet, Tekniska fakulteten. NED Univ Engn and Technol, Dept Elect Engn, Pakistan.
    Highly Linear Inductively Degenerated 0.13 mu m CMOS LNA using FDC Technique2014Ingår i: 2014 IEEE ASIA PACIFIC CONFERENCE ON CIRCUITS AND SYSTEMS (APCCAS), IEEE , 2014, 225-228 s.Konferensbidrag (Refereegranskat)
    Abstract [en]

    In this paper, a highly linear, inductively degenerated, common source narrowband LNA is presented. An extremely simple feed-forward distortion circuit (FDC) which consists of an appropriately sized ac-coupled diode connected NMOS is proposed. This circuit generates distortion components at output, when added at the input node as a feed forward element (M-6). These distortion components partially cancel the 3rd order nonlinearity of the cascode pair (M-2 and M-3), thus improving the overall linearity of LNA. The prototype is manufactured in standard 0.13 mu m CMOS process from IBM. Simulation and partial measurement results show the S11 and S22 to be -19.27dB and -7.14dB respectively at 2.45GHz. The simulation results of the LNA demonstrate a power gain of 18.5dB, NF of 4.38dB, input referred 1dBCP of -11.76dBm and IIP3 of +0.7dBm consuming 27.7mA from 1.0V power supply. The proposed LNA achieves the best input referred IIP3 reported in recent literature using 0.13 mu m CMOS in 2.4GHz frequency band.

  • 255.
    Arvanitaki, Antonia
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Pappas, Nikolaos
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Modeling of a UAV-based Data Collection System2017Ingår i: IEEE 22nd International Workshop on Computer Aided Modeling and Design of Communication Links and Networks (CAMAD), Lund, Sweden, 2017Konferensbidrag (Refereegranskat)
  • 256.
    Arvola, Mattias
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Tekniska högskolan.
    Blomkvist, Johan
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Tekniska högskolan.
    Holmlid, Stefan
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Tekniska högskolan.
    Pezone, Giovanni
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    A Service Walkthrough in Astrid Lindgren's Footsteps2012Ingår i: Proceedings from ServDes.2012 Conference Proceedings Co-Creating Services, The 3rd Service Design and Service Innovation Conference, 8-10 February, Espoo, Finland, Linköping: Linköping University Electronic Press, 2012, 21-29 s.Konferensbidrag (Refereegranskat)
    Abstract [en]

    How can service prototypes be created and evaluated? This paper describes how methods like bodystorming and experience prototyping can be used in combination with pluralistic walkthrough in an evaluation method we call ‘service walkthrough’. We put the method to test in the development of augmented tourism services at the author Astrid Lindgren's childhood home. After initial design work, a mock-up and roleplay of a treasure hunt in the garden of the childhood home was made. It was evaluated using the service walkthrough method. The most important lesson learned was that a service walkthrough can be used to evaluate service prototypes and that it reveals information about practical as well as experiential issues for users.

  • 257.
    Arvola, Mattias
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Filosofiska fakulteten.
    Holmlid, Stefan
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Tekniska fakulteten.
    Service Design Ways to Value-In-Use2016Ingår i: Service design geographies: Proceedings of the ServDes2016 Conference / [ed] Nicola Morelli, Amalia de Götzen, Francesco Grani, Linköping: Linköping University Electronic Press, 2016, Vol. 125, 530-536 s.Konferensbidrag (Refereegranskat)
    Abstract [en]

    What do we mean if we say that a service design work is an example of good design? This paper presents a provisional typology for the ways in which a service design proposal can contribute to value-in-use. The typology covers instrumentality, technical excellence, usefulness, social significance, mutual advantage, collective welfare, and aesthetic values. Moral implications related to norms, power structures and tensions between stakeholders are also considered. It is argued that the typology can facilitate service designers and researchers in framing and re-framing a design effort and conceptualise a value proposition. 

  • 258.
    Arvola, Mattias
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Filosofiska fakulteten.
    Holmlid, Stefan
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Tekniska fakulteten.
    User Experience Qualities and the Use-Quality Prism2015Ingår i: The fuzzy front end of experience design: Workshop proceedings / [ed] Eija Kaasinen, Hannu Karvonen, Yichen Lu, Jari Varsaluoma, Heli Väätäjä, Espoo: VTT , 2015Konferensbidrag (Refereegranskat)
    Abstract [en]

    Deciding the desirable user experience qualities, i.e. UX goals, for a future product or service is important but difficult. This case study explores how a set of qualities is articulated in the concept design process. The case is a project aimed at exploring the use of smartphones to augment the childhood home of Astrid Lindgren—the children’s book author—with stories about her life and authorship. The results showed that articulated UX qualities focused the design work. It was also observed that one set of desirable qualities does not fit all phases in a project, and design consequences propagate between aspects of UX quality. 

  • 259.
    Arvola, Mattias
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Filosofiska fakulteten.
    Nordvall, Mathias
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Tekniska fakulteten. SICS East Swedish ICT, Linköping, Sweden.
    Broth, Mathias
    Linköpings universitet, Institutionen för kultur och kommunikation, Avdelningen för språk och kultur. Linköpings universitet, Filosofiska fakulteten.
    Transmodal interaction and user experience2016Ingår i: Proceedings of the 12'th SweCog Conference / [ed] Alexander Almér, Robert Lowe, Erik Billing, Skövde: The University of Skövde , 2016, 5-5 s.Konferensbidrag (Övrigt vetenskapligt)
    Abstract [en]

    We are in a series of studies, ranging from news production to computer gaming, looking into the intersection of transmodal interaction and user experience. The purpose of this abstract is to outline the theoretical framework for that intersection. The first area we are studying is Transmodal Interaction, which is a concept that refer to a specific aspect of multimodal interaction. Human action is multimodal (Streeck, Goodwin, & LeBaron, 2011), and different sensory modes play an important role in action. However, little attention has been given to the intricate ways in which sensory modalities (seeing – drawing, hearing – saying, moving – touching, etc.) integrate, affect, and transform each other during the course of an activity. There are transformations of meaning in every new materialisation of an idea or a thought, partly depending on the communication potential of the sensory modality. This render what we refer to as a transmodal process where ideas and thoughts materialise action by action in an emergent sequence across relatively long and discontinuous timespans (Murphy, 2012). Over a sequence of actions, the meanings expressed in one modality, dynamically blend and shape what is expressed in other modalities. This produces, according to (Murphy, 2012) “a series of semiotic modulations in which certain core qualities persist, but others are noticeably transformed in the transition from one mode to another. (p. 1969)” We can, in intersemiotic translation (Jakobson, 1959) between modalities, address what is lost, how we introduce distortions, or even introduce perceptions of things that do not exist. A question is then how continuity of meaning and experience is preserved in modality changes. The second area we are studying is User Experience. The term refers to a person's perceptions and responses resulting from the use and/or anticipated use of a product, system or service (ISO, 2010). We employ a three level model of user experience based on Leontiev’s account of consciousness (Kaptelinin & Nardi, 2012; Leont ́ev, 1978), which also relate closely to Norman’s model of emotional design (Norman, 2005). The first level is the sensory fabric of consciousness, Norman refers to this as the visceral level. It is the largely subconscious level of how things feel. The second level is the personal meaning of things, related to what and how we do things action by action. Norman (ibid.) refers to this level as the behavioural level. The third level has to do with meaning, and what Norman refers to as a reflective level. It is the level of cultural meaning and what things mean for us in our socially and historically rooted activities. The intersection of these two areas constitutes our current focus of research. We are, in domains as different as news production and computer gaming, investigating persons’ perceptions and actions resulting from interaction with each other and with materialisations across different sensory modalities that give rise to intersemiotic translation effects. 

    References ISO. (2010). ISO 9241-210: 2010 Ergonomics of human-system interaction -- Part 210: Human-centred design. Geneva: International Standardization Organization. Jakobson, R. (1959). On linguistic aspects of translation. In R. A. Brower (Ed.), On translation (pp. 232-239). Cambridge, Mass.: Harvard University Press. Kaptelinin, V., & Nardi, B. (2012). Activity theory in HCI: Fundamentals and Reflections. Synthesis Lectures on Human-Centered Informatics, 5(1), 1-105.  Leont´ev, A. N. (1978). Activity, Consciousness, and Personality. Englewood Cliffs, NJ.: Prentice-Hall. Murphy, K. M. (2012). Transmodality and temporality in design interactions. Journal of Pragmatics, 44(14), 1966-1981. doi:10.1016/j.pragma.2012.08.013 Norman, D. A. (2005). Emotional design: Why we love (or hate) everyday things. New York, NY.: Basic Books. Streeck, J. r., Goodwin, C., & LeBaron, C. (2011). Embodied interaction: language and body in the material

  • 260.
    Arvola, Mattias
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Filosofiska fakulteten.
    Nordvall, Mathias
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Tekniska fakulteten.
    Hägglund, Sture
    SICS East Swedish ICT.
    Hult, Lars
    SICS East Swedish ICT.
    Katarina, Bohm
    Karolinska Institutet, Institution of Clinical Science and Education, Södersjukhuset.
    Multi-Touchpoint Design of Multimodal Healthcare Services2016Konferensbidrag (Refereegranskat)
    Abstract [en]

    The purpose of this paper is to identify research themes and outline a research-through-design project that will explore opportunities and challenges in human-centred multi- touchpoint design for multimodal emergency calls, healthcare counselling, and elderly patient monitoring. Relevant research areas for the project include multimodal user interfaces and interaction, transmodality, accessibility, and multi-touchpoint user experience (UX) and service design. Research questions will primarily focus on opportunities and challenges of interaction and visualisation; dialogue and communication; and operations and organisation. On a higher level, beyond the specific case, the overarching research questions concern what roles modalities play in multi-touchpoint UX and service design. The knowledge contribution is a better understanding of how different modalities can be designed, employed, combined, and transduced in and between multiple touchpoints. 

  • 261.
    Arvola, Mattias
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Filosofiska fakulteten.
    Walfridsson, Andreas
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    The Mediated Action Sheets: Structuring the Fuzzy Front-End of UX2015Ingår i: The fuzzy front end of experience design: Workshop proceedings / [ed] Eija Kaasinen, Hannu Karvonen, Yichen Lu, Jari Varsaluoma, Heli Väätäjä, Espoo: VTT , 2015Konferensbidrag (Refereegranskat)
    Abstract [en]

    Decisions about what to design, for whom, and why to design it, are made during the fuzzy front of user experience (UX) design. Our approach to structure this process is to use a theoretical and methodological framework based on mediated action. This position paper describes how we put the framework, called the Mediated Action Sheets, to test in UX design practice. The test consisted of two workshops with professional designers. Transcripts of video recordings and results were qualitatively analyzed. The results are used to improve the framework. 

  • 262.
    Arwin, Hans
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska högskolan.
    Magnusson, Roger
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska högskolan.
    Fernández del Río, Lia
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska högskolan.
    Åkerlind, Christina
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska högskolan. Swedish Defence Research Agency, Linköping, Sweden.
    Muñoz-Pineda, Eloy
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska högskolan. Cinvestav-IPN, Unidad Querétaro, Libramiento Norponiente 2000, 76230 Querétaro, Mexico.
    Landin, Jan
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Mendoza-Galván, Arturo
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Cinvestav-IPN, Unidad Querétaro, Libramiento Norponiente 2000, 76230 Querétaro, Mexico.
    Järrendahl, Kenneth
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska fakulteten.
    Exploring optics of beetle cuticles with Mueller-matrix ellipsometry2014Ingår i: Materials Today, ISSN 1369-7021, Vol. 1S, 155-160 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Spectroscopic Mueller-matrix ellipsometry at variable angles of incidence is applied to beetle cuticles using a small (50 -100 μm) spot size. It is demonstrated how ellipticity and degree of polarization of the reflected light can be derived from a Mueller matrix providing a detailed insight into reflection properties. Results from Cetonia aurata, Chrysina argenteola and Cotinis mutabilis are presented. The use of Mueller matrices in regression analysis to extract structural and optical parameters of cuticles is briefly described and applied to cuticle data from Cetonia aurata whereby the pitch of the twisted layered structure in the cuticle is determined as well as the refractive indices of the epicuticle and the exocuticle.

  • 263.
    Arwin, Hans
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska fakulteten.
    Magnusson, Roger
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska fakulteten.
    Garcia-Caurel, Enric
    CNRS 91128 Palaiseau, France.
    de Martino, Antonello
    CNRS 91128 Palaiseau, FranceCNRS 91128 Palaiseau, France.
    Järrendahl, Kenneth
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska fakulteten.
    Ossikovski, Razvigor
    CNRS 91128 Palaiseau, France.
    Sum decomposition of Mueller matrices from beetle cuticles2015Konferensbidrag (Övrigt vetenskapligt)
    Abstract [en]

    Spectral Mueller matrices are very rich in information about physical properties of a sample. We have recently shown that polarizing properties like ellipticity and degree of polarization can be extracted from a Mueller matrix measured on a beetle cuticle (exoskeleton). Mueller matrices can also be used in regression analysis to model nanostructures in cuticles. Here we present the use of sum decomposition of Mueller matrices from these depolarizing biological reflectors to explore the fundamental character of these reflectors. The objective is to decompose a Mueller matrix into well- defined ideal non-depolarizing matrices corresponding to mirrors, circular polarizers, halfwave retarders etc.Generally it is possible to decompose a measured depolarizing Mueller matrix M into four (or fewer) non-depolarizing matrices according to M=λ1M1+λ2M2+λ3M3+λ4M4, where λ1, λ2, λ3 and λ4 are eigenvalues of the covariance matrix of M. Two strategies for decomposition will be discussed. A Cloude decomposition will provide the eigenvalues and also the Mi’s although the latter will contain severe noise in some spectral regions. However, a major advantage with the Cloude decomposition is that the number of nonzero eigenvalues is directly obtained, i.e. the number of contributing Mi matrices. In an alternative decomposition, the Mi’s are assumed and the eigenvalues are found by regression analysis based on M. In the case with two non-zero eigenvalues we define a model Mueller matrix MD=αRM1+βRM2 with αR+βR=1. With αR as adjustable parameter, the Frobenius norm ||M-MD|| is minimized for each wavelength in the spectral range of M. For more complex structures, the regression can be extended by adding more matrices up to a total of four. Advantages with a regression approach are its simplicity and stability compared to a Cloude decomposition.Mueller-matrix spectra of beetle cuticles are recorded with a dual rotating compensator ellipsometer in the spectral range 400 – 900 nm at angles of incidence in the range 20 - 75°. The application of decomposition on biological reflectors is demonstrated on M measured on the beetle Cetonia aurata, which represents a narrow-band chiral Bragg reflector with two non-zero eigenvalues. A decomposition in an ideal mirror and a circular polarizer is feasible. In another example, the broad-band and gold-colored beetle Chrysina argenteola, we show that more than two eigenvalues can be nonzero, especially at oblique incidence, and additional matrices are involved.

  • 264.
    Arwin, Hans
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska högskolan.
    Magnusson, Roger
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska fakulteten.
    Garcia-Caurel, Enric
    Laboratoire des Physique des Interfaces et Couches Minces, Ecole Polytechnique, CNRS, France.
    Fallet, C.
    Bioaxial SAS, 40 rue de Paradis, France.
    Järrendahl, Kenneth
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska högskolan.
    Foldyna, M.
    Laboratoire des Physique des Interfaces et Couches Minces, Ecole Polytechnique, CNRS, France.
    De Martino, A.
    Laboratoire des Physique des Interfaces et Couches Minces, Ecole Polytechnique, CNRS, France.
    Ossikovski, R.
    Laboratoire des Physique des Interfaces et Couches Minces, Ecole Polytechnique, CNRS, France.
    Sum decomposition of Mueller-matrix images and spectra of beetle cuticles2015Ingår i: Optics Express, ISSN 1094-4087, Vol. 23, nr 3, 1951-1966 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Spectral Mueller matrices measured at multiple angles of incidence as well as Mueller matrix images are recorded on the exoskeletons (cuticles) of the scarab beetles Cetonia aurata and Chrysina argenteola. Cetonia aurata is green whereas Chrysina argenteola is gold-colored. When illuminated with natural (unpolarized) light, both species reflect left-handed and near-circularly polarized light originating from helicoidal structures in their cuticles. These structures are referred to as circular Bragg reflectors. For both species the Mueller matrices are found to be nondiagonal depolarizers. The matrices are Cloude decomposed to a sum of non-depolarizing matrices and it is found that the cuticle optical response, in a first approximation can be described as a sum of Mueller matrices from an ideal mirror and an ideal circular polarizer with relative weights determined by the eigenvalues of the covariance matrices of the measured Mueller matrices. The spectral and image decompositions are consistent with each other. A regression-based decomposition of the spectral and image Mueller matrices is also presented whereby the basic optical components are assumed to be a mirror and a circular polarizer as suggested by the Cloude decomposition. The advantage with a regression decomposition compared to a Cloude decomposition is its better stability as the matrices in the decomposition are determined a priori. The origin of the depolarizing features are discussed but from present data it is not possible to conclude whether the two major components, the mirror and the circular polarizer are laterally separated in domains in the cuticle or if the depolarization originates from the intrinsic properties of the helicoidal structure.

  • 265.
    Arwin, Hans
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska fakulteten.
    Mendoza-Galvan, A.
    Cinvestav IPN, Mexico.
    Magnusson, Roger
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska fakulteten.
    Andersson, Anette
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten.
    Landin, Jan
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Ekologi. Linköpings universitet, Tekniska fakulteten.
    Järrendahl, Kenneth
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tillämpad optik. Linköpings universitet, Tekniska fakulteten.
    Garcia-Caurel, E.
    University of Paris Saclay, France.
    Ossikovski, R.
    University of Paris Saclay, France.
    Structural circular birefringence and dichroism quantified by differential decomposition of spectroscopic transmission Mueller matrices from Cetonia aurata2016Ingår i: Optics Letters, ISSN 0146-9592, E-ISSN 1539-4794, Vol. 41, nr 14, 3293-3296 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Transmission Mueller-matrix spectroscopic ellipsometry is applied to the cuticle of the beetle Cetonia aurata in the spectral range 300-1000 nm. The cuticle is optically reciprocal and exhibits circular Bragg filter features for green light. By using differential decomposition of the Mueller matrix, the circular and linear birefringence as well as dichroism of the beetle cuticle are quantified. A maximum value of structural optical activity of 560 degrees/mm is found. (C) 2016 Optical Society of America

  • 266.
    Arwinge, Olof
    et al.
    Swedbank, Sweden.
    Nilsson, Fredrik
    Företagsekonomiska institutionen, Uppsala universitet, Sweden.
    Olve, Nils-Göran
    Linköpings universitet, Tekniska fakulteten. Linköpings universitet, Institutionen för ekonomisk och industriell utveckling, Industriell ekonomi.
    Intern styrning och kontroll med särskilt fokus på försäkringssektorn2015Ingår i: Trovärdighet och förtroende i ekonomiska relationer / [ed] Peter Öhman, Heléne Lundberg, Lund: Studentlitteratur AB, 2015, 1, 95-124 s.Kapitel i bok, del av antologi (Övrigt vetenskapligt)
    Abstract [sv]

    De fem servicebranscherna bank, försäkring, pension, fastighet och revision har viktiga samhällsfunktioner och därmed behov av att skapa trovärdiga och förtroendefulla ekonomiska relationer. Detta förutsätter informationsutbyte, styrning, kontroll och samverkan. Formerna för detta, liksom för arbetssätt och beslutsfattande, har förändrats, och i Trovärdighet och förtroende i ekonomiska relationer visas hur detta har skapat både problem och möjligheter.

    I boken diskuteras de fem servicebranschernas verksamhet såväl teoretiskt som praktiskt. Vi får ta del av både den historiska framväxten och de utmaningar branscherna står inför idag. Det ges också exempel på hur ökad reglering, teknikutveckling och globalisering kommit att påverka utvecklingen, på gott och ont. I ett summerande kapitel diskuterar representanter från branscherna de resultat som presenterats i bokens övriga delar.

    Boken vänder sig i första hand till universitets- och högskole­studenter i företagsekonomi och service management, men även till forskare samt yrkesverksamma inom de fem branscherna.

  • 267.
    Asad, Sara
    et al.
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Calmfors, Tomas
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Forzelius, Magnus
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Fransson, Ellen
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Granath, Vilhelm
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Johansson, Axel
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Karlsson, Lisa
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Werdin, Andreas
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Pralinbutiken: Erfarenheter från utvecklingen av en webbapplikation2015Självständigt arbete på grundnivå (kandidatexamen), 12 poäng / 18 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Denna rapport beskriver arbetet med att utveckla en e-butik för egenkomponerade askar med chokladpraliner, Pralinbutiken, utifrån den agila utvecklingsmetodiken Scrum. Arbetet har utförts av ett team bestående av åtta studenter vid Linköpings Universitet som en del i ett kandidatarbete inom Civilingenjörsprogrammet i industriell ekonomi.

    Teamet kom fram med idé och koncept till Pralinbutiken. Rapporten tar upp erfarenheter kring utvecklingsprocessen, arbetsmetodiken och teamet. Vidare presenteras och diskuteras tekniska problem samt lösningar som uppkommit under projektets gång.

    Målet med Pralinbutiken är att erbjuda en egenkomponerad pralinask anpassad efter kundernas egna allergier och önskemål.

    Tack till Ejes Choklad, Pralinaskar.se och DarkPassion för ert bidragande med bilder på produkter till Pralinbutikens sortiment. 

  • 268.
    Asada, Satoshi
    et al.
    Department of Electronic Science and Engineering, Kyoto University, Katsura, Nishikyo, Kyoto, Japan.
    Kimoto, Tsunenobu
    Department of Electronic Science and Engineering, Kyoto University, Katsura, Nishikyo, Kyoto, Japan.
    Ivanov, Ivan Gueorguiev
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Halvledarmaterial. Linköpings universitet, Tekniska fakulteten.
    Calibration on wide-ranging aluminum doping concentrations by photoluminescence in high-quality uncompensated p-type 4H-SiC2017Ingår i: Applied Physics Letters, ISSN 0003-6951, E-ISSN 1077-3118, Vol. 111, nr 7, 072101Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Previous work has shown that the concentration of shallow dopants in a semiconductor can be estimated from the photoluminescence (PL) spectrum by comparing the intensity of the bound-to-the- dopant exciton emission to that of the free exciton. In this work, we study the low-temperature PL of high-quality uncompensated Al-doped p-type 4H-SiC and propose algorithms for determining the Al-doping concentration using the ratio of the Al-bound to free-exciton emission. We use three different cryogenic temperatures (2, 41, and 79 K) in order to cover the Al-doping range from mid 10(14) cm(-3) up to 10(18) cm(-3). The Al-bound exciton no-phonon lines and the strongest free-exciton replica are used as a measure of the bound-and free-exciton emissions at a given temperature, and clear linear relationships are obtained between their ratio and the Al-concentration at 2, 41, and 79 K. Since nitrogen is a common unintentional donor dopant in SiC, we also discuss the criteria allowing one to determine from the PL spectra whether a sample can be considered as uncompensated or not. Thus, the low-temperature PL provides a convenient non-destructive tool for the evaluation of the Al concentration in 4H-SiC, which probes the concentration locally and, therefore, can also be used for mapping the doping homogeneity. Published by AIP Publishing.

  • 269.
    Aschebrock, Thilo
    et al.
    University of Bayreuth, Germany.
    Armiento, Rickard
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Fysik. Linköpings universitet, Tekniska fakulteten.
    Kuemmel, Stephan
    University of Bayreuth, Germany.
    Challenges for semilocal density functionals with asymptotically nonvanishing potentials2017Ingår i: Physical Review B, ISSN 2469-9950, E-ISSN 2469-9969, Vol. 96, nr 7, 075140Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The Becke-Johnson model potential [A. D. Becke and E. R. Johnson, J. Chem. Phys. 124, 221101 ( 2006)] and the potential of the AK13 functional [R. Armiento and S. Kummel, Phys. Rev. Lett. 111, 036402 ( 2013)] have been shown to mimic features of the exact Kohn-Sham exchange potential, such as step structures that are associated with shell closings and particle-number changes. A key element in the construction of these functionals is that the potential has a limiting value far outside a finite system that is a system-dependent constant rather than zero. We discuss a set of anomalous features in these functionals that are closely connected to the nonvanishing asymptotic potential. The findings constitute a formidable challenge for the future development of semilocal functionals based on the concept of a nonvanishing asymptotic constant.

  • 270.
    Aschebrock, Thilo
    et al.
    University of Bayreuth, Germany.
    Armiento, Rickard
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Fysik. Linköpings universitet, Tekniska fakulteten.
    Kuemmel, Stephan
    University of Bayreuth, Germany.
    Orbital nodal surfaces: Topological challenges for density functionals2017Ingår i: Physical Review B, ISSN 2469-9950, E-ISSN 2469-9969, Vol. 95, nr 24, 245118Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Nodal surfaces of orbitals, in particular of the highest occupied one, play a special role in Kohn-Sham density-functional theory. The exact Kohn-Sham exchange potential, for example, shows a protruding ridge along such nodal surfaces, leading to the counterintuitive feature of a potential that goes to different asymptotic limits in different directions. We show here that nodal surfaces can heavily affect the potential of semilocal density-functional approximations. For the functional derivatives of the Armiento-Kummel (AK13) [Phys. Rev. Lett. 111, 036402 (2013)] and Becke88 [Phys. Rev. A 38, 3098 (1988)] energy functionals, i.e., the corresponding semilocal exchange potentials, as well as the Becke-Johnson [J. Chem. Phys. 124, 221101 (2006)] and van Leeuwen-Baerends (LB94) [Phys. Rev. A 49, 2421 (1994)] model potentials, we explicitly demonstrate exponential divergences in the vicinity of nodal surfaces. We further point out that many other semilocal potentials have similar features. Such divergences pose a challenge for the convergence of numerical solutions of the Kohn-Sham equations. We prove that for exchange functionals of the generalized gradient approximation (GGA) form, enforcing correct asymptotic behavior of the potential or energy density necessarily leads to irregular behavior on or near orbital nodal surfaces. We formulate constraints on the GGA exchange enhancement factor for avoiding such divergences.

  • 271.
    Asekritova, Irina
    et al.
    Linköpings universitet, Matematiska institutionen, Matematik och tillämpad matematik. Linköpings universitet, Tekniska fakulteten.
    Kruglyak, Natan
    Linköpings universitet, Matematiska institutionen, Matematik och tillämpad matematik. Linköpings universitet, Tekniska fakulteten.
    Mastylo, Mieczyslaw
    University of Poznan, Poland.
    Interpolation of Fredholm Operators2016Ingår i: Advances in Mathematics, ISSN 0001-8708, E-ISSN 1090-2082, Vol. 295, 421-496 s.Artikel i tidskrift (Refereegranskat)
  • 272.
    Asghar, Adeel
    et al.
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Pfeiffer, Andreas
    DLR Institute of System Dynamic and Control, Wessling, Tyskland.
    Palanisamy, Arunkumar
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Mengist, Alachew
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Sjölund, Martin
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Pop, Adrian
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Fritzson, Peter
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Automatic Regression Testing of Simulation Models and Concept for Simulation of Connected FMUs in PySimulator2015Ingår i: Proceedings of the 11th International Modelica Conference: Versailles, France, September 21-23, 2015 / [ed] Peter Fritzson, Hilding Elmqvist, Linköping, 2015, 671-679 s.Konferensbidrag (Refereegranskat)
    Abstract [en]

    The Modelica and FMI tool ecosystem is growing each year with new tools and methods becoming available. The open Modelica standard promises portability but it is important to ensure that a certain model behaves the same in different Modelica tools or in a different version of the same tool. It is also very important (for model evolution) to check that a new version of the same model produces comparable results. Finally, it is desirable to verify that a model exported in FMU form from a Modelica tool gives exactly the same results as the original model. This paper presents a framework for automatic regression testing as part of PySimulator which provides an efficient and concise way of testing if a model or a range of models behaves in the same way in several tools or versions of a tool by checking that the results produced are essentially identical. The FMI standard has been adopted by many tool vendors and is growing in popularity each year. This paper proposes a concept for building and simulating a system made from connected FMUs generated by different tools. The FMUs for Co-Simulation can be connected together using a GUI. The system model built graphically in this way can be saved for later use or simulated directly inside PySimulator. Active development is going on to support simulation of connected FMUs for Model Exchange.

  • 273.
    Asgharian Bourkheili, Ehsan
    Linköpings universitet, Institutionen för ekonomisk och industriell utveckling, Industriell ekonomi. Linköpings universitet, Tekniska fakulteten.
    Performance in Franchise Systems: The Franchisee Perspective2015Doktorsavhandling, monografi (Övrigt vetenskapligt)
    Abstract [en]

    During the last decades, franchising as an organizational form has received a lot of attention from researchers and practitioners alike. While many studies have examined various aspects of franchising from the franchisor's perspective, little research has taken the franchisee’s perspective. Therefore, given the importance of franchisees in a franchise system, the lack of research about consequences from the franchisee's perspective, and that many of the previous studies have taken a top-bottom view, this research concentrated on the franchisee's performance. This study focused on business format franchising in the restaurant industry in two countries, Iran and Sweden.

    In this study, the three perspectives of entrepreneurship, strategic management, and marketing were used to study the franchisee’s performance. Moreover, the resourcebased view, relational view, and relational exchange theory have been used to find the influential factors in a franchisee’s performance. Therefore, by considering franchising as a mutual relationship and examining the influential factors in a franchisee's performance, the related factors of both the franchisor and franchisee, as well as the relationship between them, were examined.

    According to the franchisee’s related factors, the franchisor's related factors, and the relationship and environmental factors, 12 main hypotheses and 9 sub-hypotheses were developed. In total, 191 usable questionnaires from Sweden and Iran, comprising a response rate of 22 percent, were returned from the franchisees. In this study, confirmatory factor analysis was used to test the construct measurement; to test the hypothesis, hierarchical multiple regression analysis was performed. Moreover, the Chow test was conducted to integrate the data from these two countries.

    A primary contribution of this study is taking a bottom-top view in franchising research. This study also provided a detailed and holistic view about the consequences of franchising for franchisees. Moreover, this study, offers important contributions toward understanding entrepreneurial activities, as a controversial issue, in franchising outlets.

    The results provide interesting insights into the franchisee’s performance. While the franchisees’ related factors of absorptive capacity, Kirznerian entrepreneurial orientation, and social capital positively affected their performance, Schumpeterian entrepreneurial orientation and human capital did not affect their performance. Moreover, the franchisor’s related factors of system profitability, brand reputation, advertisement and providing raw material had a positive influence on the performance. However, training did not cause a difference in the franchisee’s performance. All relationship factors also positively affected the performance, and conflict and satisfaction mediated the relationship between trust and performance. Finally, the implications of this study and suggestions for further contributions in this stream of research are discussed.

  • 274.
    Ashaduzzaman, Md
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten. University of Dhaka, Bangladesh.
    Anto Antony, Aswathi
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten.
    Murugan, N. Arul
    Royal Institute Technology, Sweden.
    Deshpande, Swapneel R.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten.
    Turner, Anthony
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten.
    Tiwari, Ashutosh
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten. Tekidag AB, UCS, S-58330 Linkoping, Sweden.
    Studies on an on/off-switchable immunosensor for troponin T2015Ingår i: Biosensors & bioelectronics, ISSN 0956-5663, E-ISSN 1873-4235, Vol. 73, 100-107 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Regeneration is a key goal in the design of immunosensors. In this study, we report the temperature-regulated interaction of N-isopropylacrylamide (PNIPAAm) functionalised cardiac troponin T (cTnT) with anti-cTnT. Covalently bonded PNIPAAm on an anti-cTnT bioelectrode showed on/off-switchability, regeneration capacity and temperature triggered sensitivity for cTnT. Above the lower critical solution temperature (LCST), PNIPAAm provides a liphophilic microenvironment with specific volume reduction at the bioelectrode surface, making available binding space for cTnT, and facilitating analyte recognition. Computational studies provide details about the structural changes occurring at the electrode above and below the LCST. Furthermore, free energies associated with the binding of cTnT with PNIPAAm at 25 (Delta G(coil)=-6.0 Kcal/mole) and 37 degrees C (Delta G(globular)=-41.0 kcal/mole) were calculated to elucidate the interaction and stability of the antigen-antibody complex. The responsiveness of such assemblies opens the way for miniaturised, smart immuno-technologies with built-in programmable interactions of antigen-antibody upon receiving stimuli.

  • 275.
    Ashaduzzaman, Md.
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten. UCS, Institute Adv Mat, Teknikringen 4A,Mjardevi Science Pk, SE-58330 Linkoping, Sweden.
    Deshpande, Swapneel R.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten. UCS, Institute Adv Mat, Teknikringen 4A,Mjardevi Science Pk, SE-58330 Linkoping, Sweden.
    Arul Murugan, N.
    Royal Institute Technology, Sweden.
    Kumar Mishra, Yogendra
    University of Kiel, Germany.
    Turner, Anthony
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten.
    Tiwari, Ashutosh
    Linköpings universitet, Institutionen för fysik, kemi och biologi. Linköpings universitet, Tekniska fakulteten. UCS, Institute Adv Mat, Teknikringen 4A,Mjardevi Science Pk, SE-58330 Linkoping, Sweden; Vinoba Bhave Research Institute, India.
    On/off-switchable LSPR nano-immunoassay for troponin-T2017Ingår i: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 7, 44027Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Regeneration of immunosensors is a longstanding challenge. We have developed a re-usable troponin-T (TnT) immunoassay based on localised surface plasmon resonance (LSPR) at gold nanorods (GNR). Thermosensitive poly(N-isopropylacrylamide) (PNIPAAM) was functionalised with anti-TnT to control the affinity interaction with TnT. The LSPR was extremely sensitive to the dielectric constant of the surrounding medium as modulated by antigen binding after 20 min incubation at 37 degrees C. Computational modelling incorporating molecular docking, molecular dynamics and free energy calculations was used to elucidate the interactions between the various subsystems namely, IgG-antibody (c. f., anti-TnT), PNIPAAM and/or TnT. This study demonstrates a remarkable temperature dependent immuno-interaction due to changes in the PNIPAAM secondary structures, i.e., globular and coil, at above or below the lower critical solution temperature (LCST). A series of concentrations of TnT were measured by correlating the lambda(LSPR) shift with relative changes in extinction intensity at the distinct plasmonic maximum (i. e., 832 nm). The magnitude of the red shift in lambda(LSPR) was nearly linear with increasing concentration of TnT, over the range 7.6 x 10(-15) to 9.1 x 10(-4) g/mL. The LSPR based nano-immunoassay could be simply regenerated by switching the polymer conformation and creating a gradient of microenvironments between the two states with a modest change in temperature.

  • 276. Ashaduzzaman, Md
    et al.
    Parlak, Onur
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten.
    Turner, Anthony
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten.
    Tiwari, Ashutosh
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biosensorer och bioelektronik. Linköpings universitet, Tekniska fakulteten.
    Fabrication of on/off-switchable enzymatic bioreactor for smart bioelectronics.2015Ingår i: Sweden-Japan Seminar on Nanomaterials and Nanotechnology – SJS-Nano, Linköping, Sweden, 10-11 March 2015., Japan Society for the Promotion of Science (JSPS), Stockholm , 2015, 36-37 s.Konferensbidrag (Refereegranskat)
  • 277.
    Asif, Muhammad H.
    et al.
    COMSATS Institute Informat Technology, Pakistan; Acromed Invest AB, Sweden.
    Danielsson, Bengt
    Acromed Invest AB, Sweden.
    Willander, Magnus
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Fysik och elektroteknik. Linköpings universitet, Tekniska fakulteten.
    ZnO Nanostructure-Based Intracellular Sensor2015Ingår i: Sensors, ISSN 1424-8220, Vol. 15, nr 5, 11787-11804 s.Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    Recently ZnO has attracted much interest because of its usefulness for intracellular measurements of biochemical species by using its semiconducting, electrochemical, catalytic properties and for being biosafe and biocompatible. ZnO thus has a wide range of applications in optoelectronics, intracellular nanosensors, transducers, energy conversion and medical sciences. This review relates specifically to intracellular electrochemical (glucose and free metal ion) biosensors based on functionalized zinc oxide nanowires/nanorods. For intracellular measurements, the ZnO nanowires/nanorods were grown on the tip of a borosilicate glass capillary (0.7 mu m in diameter) and functionalized with membranes or enzymes to produce intracellular selective metal ion or glucose sensors. Successful intracellular measurements were carried out using ZnO nanowires/nanorods grown on small tips for glucose and free metal ions using two types of cells, human fat cells and frog oocytes. The sensors in this study were used to detect real-time changes of metal ions and glucose across human fat cells and frog cells using changes in the electrochemical potential at the interface of the intracellular micro-environment. Such devices are helpful in explaining various intracellular processes involving ions and glucose.

  • 278.
    Askari Ghotbabadi, Sadegh
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska fakulteten. University of Ulster, North Ireland.
    Ul Haq, Atta
    University of Ulster, North Ireland.
    Macias-Montero, Manuel
    University of Ulster, North Ireland.
    Levchenko, Igor
    Queensland University of Technology, Australia.
    Yu, Fengjiao
    University of St Andrews, Scotland.
    Zhou, Wuzong
    University of St Andrews, Scotland.
    (Ken) Ostrikov, Kostya
    Queensland University of Technology, Australia; Queensland University of Technology, Australia; CSIRO, Australia.
    Maguire, Paul
    University of Ulster, North Ireland.
    Svrcek, Vladimir
    National Institute Adv Ind Science and Technology, Japan.
    Mariotti, Davide
    University of Ulster, North Ireland.
    Ultra-small photoluminescent silicon-carbide nanocrystals by atmospheric-pressure plasmas2016Ingår i: Nanoscale, ISSN 2040-3364, E-ISSN 2040-3372, Vol. 8, nr 39, 17141-17149 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Highly size-controllable synthesis of free-standing perfectly crystalline silicon carbide nanocrystals has been achieved for the first time through a plasma-based bottom-up process. This low-cost, scalable, ligand-free atmospheric pressure technique allows fabrication of ultra-small (down to 1.5 nm) nanocrystals with very low level of surface contamination, leading to fundamental insights into optical properties of the nanocrystals. This is also confirmed by their exceptional photoluminescence emission yield enhanced by more than 5 times by reducing the nanocrystals sizes in the range of 1-5 nm, which is attributed to quantum confinement in ultra-small nanocrystals. This method is potentially scalable and readily extendable to a wide range of other classes of materials. Moreover, this ligand-free process can produce colloidal nanocrystals by direct deposition into liquid, onto biological materials or onto the substrate of choice to form nanocrystal films. Our simple but efficient approach based on non-equilibrium plasma environment is a response to the need of most efficient bottom-up processes in nanosynthesis and nanotechnology.

  • 279.
    Askenberger, Erik
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Hur är relationen mellan kommunikationen i en crowdfundingkampanj och dess utfall? En studie av glassprojekt i USA på kickstarter.2015Självständigt arbete på grundnivå (kandidatexamen), 10,5 poäng / 16 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    I denna studie har tidigare forskning kring faktorer som bidragit till lyckade crowdfundingkampanjer sammanställts och en undersökning gjorts på lyckade glassprojekt från kickstarter. Crowdfunding är en relativt ny typ av investeringskanal, där man genom många och små donationer från allmänheten samlar ihop en stor summa till ett projekt. Kommunikationen i en crowdfundingkampanj verkar ha stor betydelse för hur väl ett projekt har lyckats och det gemensamma ifrån tidigare undersökningar är att ett projekt skall hålla hög kvalitet för att bli framgångsrikt. Glassprojekten som analyserats gav resultatet att antalet projektuppdateringar har ett direkt samband med resultatet. Videolängd korrelerar inte med resultatet och är inte ett mått på kampanjens kvalitet. Antalet Facebookvänner skaparen har privat påverkar kampanjens resultat med den troliga förklaringen att flertalet donationer sker från familj och vänner, och dessa donationer kan vara en indikation för andra att projektet är seröst och därmed lockar in fler donationer.

  • 280.
    Asklund Andersson, Alexandra
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Digitala spel och dyslexi2015Självständigt arbete på grundnivå (kandidatexamen), 10,5 poäng / 16 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Dagens samhälle lägger stor vikt på individens förmåga att ta till sig information i form av text men då mellan 5-8% av Sveriges befolkning beräknas lida av läs och skrivsvårigheter blir detta snabbt ett stort problem. Det faktum att dyslexi är ett dolt funktionshinder som kan ta tid att upptäcka hjälper inte de drabbade utan kan istället leda till sviktande självförtroende och låg studiemotivation.

     

    Därmed finns det ett behov för nya screeningverktyg som kan upptäcka dyslexi tidigt, det ide som specifikt är på frammarsch är att göra detta genom spel. Det är detta problem som denna studie har fokuserat på att lösa. Genom en serie på 16 kvalitativa intervjuer och 15 förebildsanalyser har författaren producerat en kravspecifikation för ett spelbaserat screeningverktyg, en sammanfattning på vad ett sådant spel bör ta hänsyn till och hur barn uppfattar spel.

    Studiens resultat sammanställdes inte bara i den tekniska kravspecifikationen utan ger även inblick i barnens åsikter samt mer praktiska förslag till ett tänkt screeningverktyg.

  • 281.
    Asp, Filip
    et al.
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Krispinsson, Tobias
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Distributed certificates in ad hoc networks2015Självständigt arbete på grundnivå (kandidatexamen), 10,5 poäng / 16 hpStudentuppsats (Examensarbete)
    Abstract [en]

    In this report an ad hoc system is defined with the capabilities to validate the integrity ofevery node in the network without a third party, as long as every node has possession of acertificate. The system is developed to function in an ad hoc network with many externalthreats. The main target group would be the military and first responders. There are manydifferent problems with such a network, and many parts have been researched, but few fullsystems have been developed. This report defines a hierarchical system where nodes cancommunicate in an encrypted way, with the help of certificates. In a military situation therisk for compromised nodes must be considered. Therefore, the system can both detectand handle compromised nodes by revocation certificates. The proposed system is alsodetecting and handling partitions. The system has been put together by first making aliterature study to find existing solutions to different problems, then making a synthesisof those solutions. We also came up with new solutions where the three cornerstones ofsecurity: availability, confidentiality and integrity were in focus. To make the solutionmore trustworthy a risk analysis on the resulting system was made, which defined theweak points of the system.

  • 282.
    Asplund, Mikael
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Model-based Membership Verification in Vehicular Platoons2015Ingår i: Proceedings: 2015 45th Annual IEEE/IFIP International Conference on Dependable Systems and Networks Workshops , IEEE Computer Society, 2015, 125-132 s.Konferensbidrag (Refereegranskat)
    Abstract [en]

    Cooperative vehicular systems have the potentialto significantly increase traffic efficiency and safety. However,they also raise the question of to what extent information thatis received from other vehicles can be trusted. In this paperwe present a novel approach for increasing the trustworthinessof cooperative driving through a model-based approach forverifying membership views in vehicular platoons. We define aformal model for platoon membership, cooperative awarenessclaims, and membership verification mechanisms. With the helpof a satisfiability solver, we are able to quantitatively analysethe impact of different system parameters on the verifiability ofreceived information. Our results demonstrate the importance ofcross validating received messages, as well as the surprising diffi-culty in establishing correct membership views despite powerfulverification mechanisms.

  • 283.
    Asplund, Mikael
    et al.
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska fakulteten.
    Lövhall, Jakob
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Villani, Emilia
    Auronatics Institute of Technology, Brazil.
    Specification, Implementation and Verification of Dynamic Group Membership for Vehicle Coordination2017Ingår i: Dependable Computing (PRDC), 2017 IEEE 22nd Pacific Rim International Symposium on, IEEE, 2017, 321-328 s.Konferensbidrag (Refereegranskat)
    Abstract [en]

    New advanced traffic management solutions with fully or semi-autonomous vehicles that communicate over a wireless interface to coordinate their driving decisions create new challenges in distributed computing. In this paper we address the problem of dynamic group membership in three stages. First, we propose three criteria to specify correctness and performance of the group views created by such algorithms in terms of soundness, completeness and freshness. Second, we develop a group membership protocol tailored for vehicular coordination. Finally, we show through simulation and model-based verification that the protocol does indeed meet the criteria and provide at least 95% perfect group membership views under as adverse conditions as 70% packet loss or very high churn rate.

  • 284.
    Asplund, Mikael
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Nadjm-Tehrani, Simin
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Attitudes and Perceptions of IoT Security in Critical Societal Services2016Ingår i: IEEE Access, E-ISSN 2169-3536, Vol. 4, 2130-2138 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A quiet revolution that impacts several sectors, ranging over transport, home automation, energy, industrial control, and health services is undergoing with addition of new networked devices leading to enhanced services. In this paper, we aim to identify information security requirements that are common over several (vertical) sectors, and in particular, ones that impact critical societal services, namely, the energy, water, and health management systems. We present the results of an interview-based study where actors in these sectors were asked about their perceptions and attitudes on the security of Internet of Things (IoT). We set these perceptions and attitudes in context through a literature review of IoT security, and relate to current challenges in this area. This paper demonstrates that despite an overall optimistic view on IoT in critical societal services, there is a lack of consensus on risks related to IoT security.

  • 285.
    Asratian, Armen
    et al.
    Linköpings universitet, Matematiska institutionen, Matematik och tillämpad matematik. Linköpings universitet, Tekniska fakulteten.
    Casselgren, Carl Johan
    Linköpings universitet, Matematiska institutionen, Matematik och tillämpad matematik. Linköpings universitet, Tekniska fakulteten. University of Southern Denmark, Denmark.
    Solution of Vizings Problem on Interchanges for the case of Graphs with Maximum Degree 4 and Related Results2016Ingår i: Journal of Graph Theory, ISSN 0364-9024, E-ISSN 1097-0118, Vol. 82, nr 4, 350-373 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Let G be a Class 1 graph with maximum degree 4 and let t amp;gt;= 5 be an integer. We show that any proper t-edge coloring of G can be transformed to any proper 4-edge coloring of G using only transformations on 2-colored subgraphs (so-called interchanges). This settles the smallest previously unsolved case of a well-known problem of Vizing on interchanges, posed in 1965. Using our result we give an affirmative answer to a question of Mohar for two classes of graphs: we show that all proper 5-edge colorings of a Class 1 graph with maximum degree 4 are Kempe equivalent, that is, can be transformed to each other by interchanges, and that all proper 7-edge colorings of a Class 2 graph with maximum degree 5 are Kempe equivalent. (C) 2015 Wiley Periodicals, Inc.

  • 286.
    Atakan, Aylin
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Nanostrukturerade material. Linköpings universitet, Tekniska fakulteten.
    Mäkie, Peter
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Nanostrukturerade material. Linköpings universitet, Tekniska fakulteten.
    Söderlind, Fredrik
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Kemi. Linköpings universitet, Tekniska fakulteten.
    Keraudy, Julien
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska fakulteten.
    Björk, Emma
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Nanostrukturerade material. Linköpings universitet, Tekniska fakulteten.
    Odén, Magnus
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Nanostrukturerade material. Linköpings universitet, Tekniska fakulteten.
    Synthesis of a Cu-infiltrated Zr-doped SBA-15 catalyst for CO2 hydrogenation into methanol and dimethyl ethert2017Ingår i: Physical Chemistry, Chemical Physics - PCCP, ISSN 1463-9076, E-ISSN 1463-9084, Vol. 19, nr 29, 19139-19149 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A catalytically active nanoassembly comprising Cu-nanoparticles grown on integrated and active supports (large pore Zr-doped mesoporous SBA-15 silica) has been synthesized and used to promote CO2 hydrogenation. The doped mesoporous material was synthesized using a sal-gel method, in which the pore size was tuned between 11 and 15 nm while maintaining a specific surface area of about 700 m(2) g (1). The subsequent Cu nanoparticle growth was achieved by an infiltration process involving attachment of different functional groups on the external and internal surfaces of the mesoporous structure such that 7-10 nm sized Cu nanoparticles grew preferentially inside the pores. Chemisorption showed improved absorption of both CO2 and H-2 for the assembly compared to pure SBA-15 and 15% of the total CO2 was converted to methanol and dimethyl ether at 250 degrees C and 33 bar.

  • 287.
    Atikuzzaman, Mohammad
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Alvarez-Rodriguez, Manuel
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Carrillo, Alejandro Vicente
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Johnsson, Martin
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Wright, Dominic
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Rodriguez-Martinez, Heriberto
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Conserved gene expression in sperm reservoirs between birds and mammals in response to mating.2017Ingår i: BMC Genomics, ISSN 1471-2164, E-ISSN 1471-2164, Vol. 18, nr 1Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Spermatozoa are stored in the oviductal functional sperm reservoir in animals with internal fertilization, including zoologically distant classes such as pigs or poultry. They are held fertile in the reservoir for times ranging from a couple of days (in pigs), to several weeks (in chickens), before they are gradually released to fertilize the newly ovulated eggs. It is currently unknown whether females from these species share conserved mechanisms to tolerate such a lengthy presence of immunologically-foreign spermatozoa. Therefore, global gene expression was assessed using cDNA microarrays on tissue collected from the avian utero-vaginal junction (UVJ), and the porcine utero-tubal junction (UTJ) to determine expression changes after mating (entire semen deposition) or in vivo cloacal/cervical infusion of sperm-free seminal fluid (SF)/seminal plasma (SP).

    RESULTS: In chickens, mating changed the expression of 303 genes and SF-infusion changed the expression of 931 genes, as compared to controls, with 68 genes being common to both treatments. In pigs, mating or SP-infusion changed the expressions of 1,722 and 1,148 genes, respectively, as compared to controls, while 592 genes were common to both treatments. The differentially expressed genes were significantly enriched for GO categories related to immune system functions (35.72-fold enrichment). The top 200 differentially expressed genes of each treatment in each animal class were analysed for gene ontology. In both pig and chicken, an excess of genes affecting local immune defence were activated, though frequently these were down-regulated. Similar genes were found in both the chicken and pig, either involved in pH-regulation (SLC16A2, SLC4A9, SLC13A1, SLC35F1, ATP8B3, ATP13A3) or immune-modulation (IFIT5, IFI16, MMP27, ADAMTS3, MMP3, MMP12).

    CONCLUSION: Despite being phylogenetically distant, chicken and pig appear to share some gene functions for the preservation of viable spermatozoa in the female reservoirs.

  • 288.
    Atikuzzaman, Mohammad
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Alvarez-Rodriguez, Manuel
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för barns och kvinnors hälsa. Linköpings universitet, Medicinska fakulteten.
    Vicente Carrillo, Alejandro
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Johnsson, Martin
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Wright, Dominic
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Rodriguez-Martinez, Heriberto
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för barns och kvinnors hälsa. Linköpings universitet, Medicinska fakulteten.
    Correction: Conserved gene expression in sperm reservoirs between birds and mammals in response to mating (vol 18, 98, 2017)2017Ingår i: BMC Genomics, ISSN 1471-2164, E-ISSN 1471-2164, Vol. 18, 563Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    n/a

  • 289.
    Atikuzzaman, Mohammad
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Bhai Mehta, Ratnesh
    Linköpings universitet, Medicinska fakulteten. Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för neuro- och inflammationsvetenskap.
    Fogelholm, Jesper
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Wright, Dominic
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Rodriguez-Martinez, Heriberto
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Mating induces the expression of immune- and pH-regulatory genes in the utero-vaginal junction containing mucosal sperm-storage tubuli of hens2015Ingår i: Reproduction, Vol. 150, nr 6, 473-483 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The female chicken, as with other species with internal fertilization, can tolerate the presence of spermatozoa within specialized sperm-storage tubuli (SST) located in the mucosa of the utero-vaginal junction (UVJ) for days or weeks, without eliciting an immune response. To determine if the oviduct alters its gene expression in response to sperm entry, segments from the oviduct (UVJ, uterus, isthmus, magnum and infundibulum) of mated and unmated (control) hens, derived from an advanced inter-cross line between Red Junglefowl and White Leghorn, were explored 24 h after mating using cDNA microarray analysis. Mating shifted the expression of fifteen genes in the UVJ (53.33% immune-modulatory and 20.00% pH-regulatory) and seven genes in the uterus, none of the genes in the latter segment overlapping the former (with the differentially expressed genes themselves being less related to immune-modulatory function). The other oviductal segments did not show any significant changes. These findings suggest sperm deposition causes a shift in expression in the UVJ (containing mucosal SST) and the uterus for genes involved in immune-modulatory and pH-regulatory functions, both relevant for sperm survival in the hen's oviduct.

  • 290.
    Atikuzzaman, Mohammad
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Sanz, Libia
    Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain.
    Pla, Davinia
    Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain.
    Alvarez-Rodriguez, Manuel
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Rubér, Marie
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Wright, Dominic
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Calvete, Juan J.
    Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain.
    Rodriguez-Martinez, Heriberto
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
    Selection for higher fertility reflects in the seminal fluid proteome of modern domestic chicken2017Ingår i: Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics, ISSN 1744-117X, E-ISSN 1878-0407, Vol. 21, 27-40 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The high egg-laying capacity of the modern domestic chicken (i.e. White Leghorn, WL) has arisen from the low egg-laying ancestor Red Junglefowl (RJF) via continuous trait selection and breeding. To investigate whether this long-term selection impacted the seminal fluid (SF)-proteome, 2DE electrophoresis-based proteomic analyses and immunoassays were conducted to map SF-proteins/cytokines in RJF, WL and a 9th generation Advanced Intercross Line (AIL) of RJF/WL-L13, including individual SF (n = 4, from each RJF, WL and AIL groups) and pools of the SF from 15 males of each group, analyzed by 2DE to determine their degree of intra-group (AIL, WL, and RJF) variability using Principal Component Analysis (PCA); respectively an inter-breed comparative analysis of intergroup fold change of specific SF protein spots intensity between breeds. The PCA clearly highlighted a clear intra-group similarity among individual roosters as well as a clear inter-group variability (e.g. between RJF, WL and AIL) validating the use of pools to minimize confounding individual variation. Protein expression varied considerably for processes related to sperm motility, nutrition, transport and survival in the female, including signaling towards immunomodulation. The major conserved SF-proteins were serum albumin and ovotransferrin. Aspartate aminotransferase, annexin A5, arginosuccinate synthase, glutathione S-transferase 2 and l-lactate dehydrogenase-A were RJF-specific. Glyceraldehyde-3-phosphate dehydrogenase appeared specific to the WL-SF while angiotensin-converting enzyme, γ-enolase, coagulation factor IX, fibrinogen α-chain, hemoglobin subunit α-D, lysozyme C, phosphoglycerate kinase, Src-substrate protein p85, tubulins and thioredoxin were AIL-specific. The RJF-SF contained fewer immune system process proteins and lower amounts of the anti-inflammatory/immunomodulatory TGF-β2 compared to WL and AIL, which had low levels- or lacked pro-inflammatory CXCL10 compared to RJF. The seminal fluid proteome differs between ancestor and modern chicken, with a clear enrichment of proteins and peptides related to immune-modulation for sperm survival in the female and fertility.

    Publikationen är tillgänglig i fulltext från 2017-11-03 13:41
  • 291.
    Atxabal, Ainhoa
    et al.
    CIC NanoGUNE, Spain.
    Braun, Slawomir
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Ytors Fysik och Kemi. Linköpings universitet, Tekniska fakulteten.
    Arnold, Thorsten
    Technical University of Dresden, Germany.
    Sun, Xiangnan
    National Centre Nanosci and Technology, Peoples R China.
    Parui, Subir
    CIC NanoGUNE, Spain.
    Liu, Xianjie
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Ytors Fysik och Kemi. Linköpings universitet, Tekniska fakulteten.
    Gozalvez, Cristian
    University of Basque Country UPV EHU, Spain.
    Llopis, Roger
    CIC NanoGUNE, Spain.
    Mateo-Alonso, Aurelio
    University of Basque Country UPV EHU, Spain; Basque Fdn Science, Spain.
    Casanova, Felix
    CIC NanoGUNE, Spain; Basque Fdn Science, Spain.
    Ortmann, Frank
    Technical University of Dresden, Germany.
    Fahlman, Mats
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Ytors Fysik och Kemi. Linköpings universitet, Tekniska fakulteten.
    Hueso, Luis E.
    CIC NanoGUNE, Spain; Basque Fdn Science, Spain.
    Energy Level Alignment at Metal/Solution-Processed Organic Semiconductor Interfaces2017Ingår i: Advanced Materials, ISSN 0935-9648, E-ISSN 1521-4095, Vol. 29, nr 19, 1606901Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Energy barriers between the metal Fermi energy and the molecular levels of organic semiconductor devoted to charge transport play a fundamental role in the performance of organic electronic devices. Typically, techniques such as electron photoemission spectroscopy, Kelvin probe measurements, and in-device hot-electron spectroscopy have been applied to study these interfacial energy barriers. However, so far there has not been any direct method available for the determination of energy barriers at metal interfaces with n-type polymeric semiconductors. This study measures and compares metal/solution-processed electron-transporting polymer interface energy barriers by in-device hot-electron spectroscopy and ultraviolet photoemission spectroscopy. It not only demonstrates in-device hot-electron spectroscopy as a direct and reliable technique for these studies but also brings it closer to technological applications by working ex situ under ambient conditions. Moreover, this study determines that the contamination layer coming from air exposure does not play any significant role on the energy barrier alignment for charge transport. The theoretical model developed for this work confirms all the experimental observations.

  • 292.
    Augusto Berrocal, Jose
    et al.
    Eindhoven University of Technology, Netherlands.
    Di Meo, Florent
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk kemi. Linköpings universitet, Tekniska fakulteten. University of Limoges, France.
    Garcia-Iglesias, Miguel
    Eindhoven University of Technology, Netherlands.
    Gosens, Ronald P. J.
    Eindhoven University of Technology, Netherlands.
    Meijer, E. W.
    Eindhoven University of Technology, Netherlands.
    Linares, Mathieu
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Bioinformatik. Linköpings universitet, Tekniska fakulteten.
    Palmans, Anja R. A.
    Eindhoven University of Technology, Netherlands.
    Consequences of conformational flexibility in hydrogen-bond-driven self-assembly processes2016Ingår i: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 52, nr 72, 10870-10873 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    We report the synthesis and self-assembly of chiral, conformationally flexible C-3-symmetrical trisamides. A strong Cotton effect is observed for the supramolecular polymers in linear alkanes but not in cyclic alkanes. MD simulations suggest 2:1 conformations of the amides within the aggregates in both types of solvents, but a chiral bias in only linear alkanes.

  • 293.
    Avgouleas, Ioannis
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    IoT Networking Resource Allocation and Cooperation2017Licentiatavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [en]

    The Internet of Things (IoT) promises that "anything that can be connected, will be connected". It comprises of Information and Communication Technologies that interconnect billions of physical and visual things with some "basic" intelligence. The emerging IoT services will be able to react with minimal human intervention and further contribute to the big data era that requires real-time, ultrareliable, ubiquitous, scalable, and heterogeneous operation.

    This thesis is the result of our investigations on problems dealing with the evolution of such technologies. First, we explore the potential of using relay i.e., intermediate, nodes that assist users to transmit their packets in a a cellular network. Paper I provides insights into how adapting the cooperation of the relay's receiver and transmitter optimizes the network-wide throughput while the relay's queue stability is guaranteed.

    The next part of the thesis copes with the resource allocation of services on IoT devices equipped with multiple network interfaces. The resources are heterogeneous and can be split among dierent interfaces. Additionally, they are not interchangeable. In paper II, we develop optimization models for this resource allocation problem, prove the complexity of the models, and derive results that give intuition into the problems. Moreover, we propose algorithms that approximate the optimal solution and show under which circumstances this is possible.

    Finally, in paper III, we present a resource allocation problem specically for smart cities services. In comparison to the previous problem denition, resources are of one type but the IoT network device can oer capacities that vary over time. Furthermore, services have a tolerance regarding their preferred scheduling, namely, their allocation over time. We parametrize each service with a pricing function to indicate its tolerance to be served at the beginning of the scheduling window. We prove that the problem is computationally hard and provide numerical results to gain insight into how different pricing weight functions impact the allocations' distribution within the scheduling window.

  • 294.
    Avgouleas, Ioannis
    et al.
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Angelakis, Vangelis
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Pappas, Nikolaos
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Utilizing multiple full-duplex relays in wireless systems with multiple packet reception2014Ingår i: 2014 IEEE 19th International Workshop on Computer Aided Modeling and Design of Communication Links and Networks (CAMAD), 2014, 193-197 s.Konferensbidrag (Refereegranskat)
    Abstract [en]

    Relay nodes with physical layer cooperation have been used extensively to assist users' transmissions in wireless networks. This network level cooperation has been lately been gaining popularity and analytical expressions of the performance of a network with up to two relay nodes exist in recent literature. In this work, we give simulation results outlining the potential network level benefits of using multiple full-duplex relay nodes. We examine configurations where multiple full-duplex transceivers offer consistent improvement and provide guidelines on using them different network conditions.

  • 295.
    Avgouleas, Ioannis
    et al.
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Pappas, Nikolaos
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Angelakis, Vangelis
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Cooperative Wireless Networking with Probabilistic On/Off Relaying2015Ingår i: 2015 IEEE 81ST VEHICULAR TECHNOLOGY CONFERENCE (VTC SPRING), IEEE , 2015Konferensbidrag (Refereegranskat)
    Abstract [en]

    In this work, we investigate the operation of energy efficient relay nodes assisting the transmission of packets from a number of users to a destination node. We study the impact of switching randomly a fraction of the relays on and off to the aggregate throughput, the average queue size and delay per packet of systems with relays transmitting in either Full-or Half-Duplex mode and under different channel transmissions characteristics. Furthermore, we prove analytically and illustrate via simulation means how these network metrics are affected.

  • 296.
    Avgouleas, Ioannis
    et al.
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Pappas, Nikolaos
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Angelakis, Vangelis
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Scheduling Services on an IoT Device Under Time-Weighted Pricing2017Ingår i: IEEE 28th Annual International Symposium on Personal, Indoor, and Mobile Radio Communications (PIMRC): Workshop on "Communications for Networked Smart Cities", IEEE conference proceedings, 2017Konferensbidrag (Refereegranskat)
    Abstract [en]

    The emerging vision of smart cities necessitates the use of Internet of Things (IoT) network devices to implement sustainable solutions that will improve the operations of urban areas. A massive amount of smart cities services may demand allocation of computational resources, such as processing power or storage, that IoT devices offer. Within this context, we present an IoT network device comprising interfaces with one specific computational resource available. The efficient utilization of available IoT resources would improve the Quality of Service (QoS) of the IoT network that serves the smart city. All resource allocations must be completed within a given scheduling window and every service is parametrized by a pricing weight function to indicate its tolerance to be served at the beginning of the scheduling window. We propose a mathematical optimization formulation to minimize the total cost of allocating all demands within the scheduling window considering the tolerance level of each service at the same time. Moreover, we prove that the problem is computationally hard and we provide numerical results to gain insight into the impact of different pricing weight functions on the allocations’ distribution within the scheduling window.

  • 297.
    Avgouleas, Ioannis
    et al.
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Pappas, Nikolaos
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Yuan, Di
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Angelakis, Vangelis
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Probabilistic Cooperation of a Full-Duplex Relay in Random Access Networks2017Ingår i: IEEE Access, E-ISSN 2169-3536, Vol. 5, 7394-7404 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    In this paper, we analyze the probabilistic cooperation of a full-duplex relay in a multiuser random-access network. The relay is equipped with on/off modes for the receiver and the transmitter independently. These modes are modeled as probabilities by which the receiver and the transmitter are activated. We provide analytical expressions for the performance of the relay queue, such as arrival and service rates, stability conditions, and the average queue size. We optimize the relays operation setup to maximize the network-wide throughput while, simultaneously, we keep the relays queue stable and lower the relays receptions and transmissions. Furthermore, we study the effect of the SINR threshold and the self-interference coefficient on the per-user and network-wide throughput. For low SINR threshold, we show under which circumstances it is beneficial to switch off the relay completely, or switch off the relays receiver only.

  • 298.
    Ax, Christian
    et al.
    Handelshögskolan vid Göteborgs universitet, Göteborg.
    Cöster, Mathias
    Linköpings universitet, Institutionen för ekonomisk och industriell utveckling, Industriell ekonomi. Linköpings universitet, Tekniska fakulteten.
    Iveroth, Einar
    Företagsekonomiska institutionen, Uppsala universitet, Uppsala.
    Strategisk prissättning: sambandet mellan strategi, prismodeller och kostnadskalkyler2016Ingår i: Strategisk ekonomistyrning: med dialog i fokus / [ed] Fredrik Nilsson, Carl-Johan Petri, Alf Westelius, Lund: Studentlitteratur AB, 2016, 123-154 s.Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 299.
    Axell, Erik
    et al.
    Dept. of Robust Telecommunications, Swedish Defence Research Agency, Sweden .
    Larsson, Erik G
    Linköpings universitet, Institutionen för systemteknik, Kommunikationssystem. Linköpings universitet, Tekniska fakulteten.
    Persson, Daniel
    Linköpings universitet, Institutionen för systemteknik, Kommunikationssystem. Linköpings universitet, Tekniska fakulteten.
    GNSS spoofing detection using multiple mobile COTS receivers2015Ingår i: ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings, Institute of Electrical and Electronics Engineers (IEEE), 2015, 3192-3196 s.Konferensbidrag (Refereegranskat)
    Abstract [en]

    In this paper we deal with spoofing detection in GNSS receivers. We derive the optimal genie detector when the true positions are perfectly known, and the observation errors are Gaussian, as a benchmark for other detectors. The system model considers three dimensional positions, and includes correlated errors. In addition, we propose several detectors that do not need any position knowledge, that outperform recently proposed detectors in many interesting cases.

  • 300.
    Axelsson, Emil
    et al.
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Medie- och Informationsteknik. Linköpings universitet, Tekniska fakulteten.
    Costa, Jonathas
    NYU, NY 10003 USA.
    Silva, Claudio
    NYU, NY 10003 USA.
    Emmart, Carter
    Amer Museum Nat Hist, NY 10024 USA.
    Bock, Alexander
    Linköpings universitet, Institutionen för teknik och naturvetenskap. Linköpings universitet, Tekniska fakulteten.
    Ynnerman, Anders
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Medie- och Informationsteknik. Linköpings universitet, Tekniska fakulteten. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Dynamic Scene Graph: Enabling Scaling, Positioning, and Navigation in the Universe2017Ingår i: Computer graphics forum (Print), ISSN 0167-7055, E-ISSN 1467-8659, Vol. 36, nr 3, 459-468 s.Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    In this work, we address the challenge of seamlessly visualizing astronomical data exhibiting huge scale differences in distance, size, and resolution. One of the difficulties is accurate, fast, and dynamic positioning and navigation to enable scaling over orders of magnitude, far beyond the precision of floating point arithmetic. To this end we propose a method that utilizes a dynamically assigned frame of reference to provide the highest possible numerical precision for all salient objects in a scene graph. This makes it possible to smoothly navigate and interactively render, for example, surface structures on Mars and the Milky Way simultaneously. Our work is based on an analysis of tracking and quantification of the propagation of precision errors through the computer graphics pipeline using interval arithmetic. Furthermore, we identify sources of precision degradation, leading to incorrect object positions in screen-space and z-fighting. Our proposed method operates without near and far planes while maintaining high depth precision through the use of floating point depth buffers. By providing interoperability with order-independent transparency algorithms, direct volume rendering, and stereoscopy, our approach is well suited for scientific visualization. We provide the mathematical background, a thorough description of the method, and a reference implementation.

    Publikationen är tillgänglig i fulltext från 2018-07-01 14:42
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