Endre søk
Begrens søket
1 - 3 of 3
RefereraExporteraLink til resultatlisten
Permanent link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Treff pr side
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sortering
  • Standard (Relevans)
  • Forfatter A-Ø
  • Forfatter Ø-A
  • Tittel A-Ø
  • Tittel Ø-A
  • Type publikasjon A-Ø
  • Type publikasjon Ø-A
  • Eldste først
  • Nyeste først
  • Skapad (Eldste først)
  • Skapad (Nyeste først)
  • Senast uppdaterad (Eldste først)
  • Senast uppdaterad (Nyeste først)
  • Disputationsdatum (tidligste først)
  • Disputationsdatum (siste først)
  • Standard (Relevans)
  • Forfatter A-Ø
  • Forfatter Ø-A
  • Tittel A-Ø
  • Tittel Ø-A
  • Type publikasjon A-Ø
  • Type publikasjon Ø-A
  • Eldste først
  • Nyeste først
  • Skapad (Eldste først)
  • Skapad (Nyeste først)
  • Senast uppdaterad (Eldste først)
  • Senast uppdaterad (Nyeste først)
  • Disputationsdatum (tidligste først)
  • Disputationsdatum (siste først)
Merk
Maxantalet träffar du kan exportera från sökgränssnittet är 250. Vid större uttag använd dig av utsökningar.
  • 1.
    Malmgren, Joel
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Iodonium Salts: Preparation, Chemoselectivity and Metal-Catalyzed Applications2014Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    This thesis concerns the preparation and use of diaryliodonium salts. In Project I various unsymmetrical diaryliodonium salts were reacted with three different nucleophiles in order to study the chemoselectivity of the reactions of the salts. The main focus of this project was to gain a deeper understanding of the underlying factors that affect the chemoselectivity in transition metal-free arylation reactions. They were found to be very nucleophile-dependent. Some nucleophiles were very sensitive to electronic effects, whereas others were sensitive to steric factors. Ultimately, some arenes are never transferred. A very interesting scrambling reaction was also observed under the reaction conditions, where unsymmetrical diaryliodonium salts form symmetrical salts in situ.

    Project II details the preparation of N-heteroaryliodonium salts via a one-pot procedure. The salts were designed so that the N-heteroaryl moiety was selectively transferred in applications both with and without transition metals. The chemoselectivity was demonstrated by selective transfer of the pyridyl group onto two different nucleophiles.

    The third project in the thesis discusses the synthesis of alkynyl(aryl)iodonium salts and alkynylbenziodoxolones from arylsilanes. This protocol could potentially be a very useful complement to the existing procedures, in which boronic acids are used.

    The last part of the thesis (Project IV) describes a C-2 selective arylation of indoles where diaryliodonium salts were used in combination with hetero-geneous palladium catalysis. This transformation was performed in water at ambient temperature to 50 °C, and tolerated variations of both the indole and the diaryliodonium salt. Importantly, several N-H indoles could be arylated. The MCF-supported Pd-catalyst showed very little leaching and it was demonstrated that the main part of the reaction occurred via heterogeneous catalysis.

  • 2.
    Malmgren, Joel
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Synthesis of Alkynyl(aryl)iodonium salts from TMS-alkynesManuskript (preprint) (Annet vitenskapelig)
  • 3.
    Malmgren, Joel
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Unsymmetrical Diaryliodonium Salts: Development and Chemoselectivity studies2013Licentiatavhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    The first part describes a chemoselectivity study on diaryliodonium salts where oxygen, nitrogen and carbon nucleophiles have been arylated. Twelve different unsymmetric phenyl(aryl)iodonium salts were designed with a systematic variation of the steric and electronic properties of the aryl group. The chemoselectivity varies greatly between the nucleophiles but several “dummy” aryl groups were identified where selective transfer of the phenyl moiety was consequently observed. HRMS studies of the salts revealed an interesting ligand exchange between the aryl groups of the iodine under certain conditions. This will aid the understanding of the mechanism operating in diaryliodonium salt arylation reactions. The results will facilitate the design of catalytic systems employing diaryliodonium salts, as well as help in search for applications with polymer-bound salts.

    The second part of the thesis describes the development of a new synthetic route towards unsymmetric diaryliodonium salts containing one heteroaryl moiety. The substrate scope of the facile one-pot protocol involves salts containing dummy groups with large steric bulk as well as electron-rich aryl groups. The utility of the salts are demonstrated in the arylation of both phenols and malonates where selective transfer of the heteroaryl moiety was consistently observed

1 - 3 of 3
RefereraExporteraLink til resultatlisten
Permanent link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf