Endre søk
Begrens søket
1 - 22 of 22
RefereraExporteraLink til resultatlisten
Permanent link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Treff pr side
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sortering
  • Standard (Relevans)
  • Forfatter A-Ø
  • Forfatter Ø-A
  • Tittel A-Ø
  • Tittel Ø-A
  • Type publikasjon A-Ø
  • Type publikasjon Ø-A
  • Eldste først
  • Nyeste først
  • Skapad (Eldste først)
  • Skapad (Nyeste først)
  • Senast uppdaterad (Eldste først)
  • Senast uppdaterad (Nyeste først)
  • Disputationsdatum (tidligste først)
  • Disputationsdatum (siste først)
  • Standard (Relevans)
  • Forfatter A-Ø
  • Forfatter Ø-A
  • Tittel A-Ø
  • Tittel Ø-A
  • Type publikasjon A-Ø
  • Type publikasjon Ø-A
  • Eldste først
  • Nyeste først
  • Skapad (Eldste først)
  • Skapad (Nyeste først)
  • Senast uppdaterad (Eldste først)
  • Senast uppdaterad (Nyeste først)
  • Disputationsdatum (tidligste først)
  • Disputationsdatum (siste først)
Merk
Maxantalet träffar du kan exportera från sökgränssnittet är 250. Vid större uttag använd dig av utsökningar.
  • 1.
    Alpe, Marianne
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Synthesis of oligosaccharides related to the capsular polysaccharides of Streptococcus pneumoniae serotype 9 and of Cryptococcus neoformans2003Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    In the present investigation, synthesis of oligosaccharides corresponding to structural elements present in the capsular polysaccharides of Streptococcus pneumoniae and Cryptococcus neoformans has been achieved. The first two sections describe the synthesis of spacer-equipped oligosaccharides corresponding to structures from the CPS of Streptococcus pneumoniae serotypes 9N, 9A and 9L, the production of which involved synthetic challenges such as the construction of β-ManNAc and α-GlcA linkages. The former challenge was met by employing azide displacement of a 2-O-triflate substituent on a β-glucoside, whereas the latter task was accomplished utilizing thioethyl glucuronic acid donors in the presence of various promoters. The pentasaccharide product obtained correspond to the complete repeating unit of the CPS of serotype 9A.

    The last two sections of this thesis describe the construction of thioglycoside di- and trisaccharide building blocks containing α-Man, β-Xyl, β-GlcA and 6-O-acetyl motifs, as well as subsequent assembly of these building blocks into oligosaccharides corresponding to the repeating units of the capsular polysaccharide of the yeast Cryptococcus neoformans. The GlcA moiety was introduced via trichloroacetimidate coupling involving the peracetylated glucuronic acid methyl ester donor, after which the subsequent necessary benzylation was performed with the di- and trisaccharides. All of the target oligosaccharides were synthesized as amino-spacer glycosides in order to make conjugation to a carrier protein possible.

  • 2.
    Balan, Daniela
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Adolfsson, Hans
    Chiral quinuclidine-based amine catalysts for the asymmetric one-pot, three-component aza-Baylis–Hillman reaction2003Inngår i: Tetrahedron Letters, Vol. 44, nr 12, s. 2521-2524Artikkel i tidsskrift (Fagfellevurdert)
  • 3. Borgström, Magnus
    et al.
    Johansson, Olof
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Lomoth, Reiner
    Berglund-Baudin, Helena
    Wallin, Staffan
    Sun, Licheng
    Åkermark, Björn
    Hammarström, Leif
    Electron Donor-Acceptor Dyads and Triads Based on Tris(bipyridine)ruthenium(II) and Benzoquinone: Synthesis, Characterization, and Photoinduced Electron Transfer Reactions2003Inngår i: Inorganic Chemistry, ISSN 0020-1669, Vol. 42, nr 17, s. 5173-5184Artikkel i tidsskrift (Fagfellevurdert)
  • 4. Dorange, Ismet
    et al.
    Löfstedt, Joakim
    Franzén, Johan
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Närhi, Katja
    Bäckvall, Jan E.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Allenes as Carbon Nucleophiles in Intramolecular Attack on (π-1,3-diene)Palladium Complexes: Evidence for trans-Carbopalladation of the 1,3-Diene2003Inngår i: Chemistry - A European Journal, ISSN 0947-6539, E-ISSN 1521-3765, Vol. 9, nr 14, s. 3445-3449Artikkel i tidsskrift (Fagfellevurdert)
  • 5.
    Edin, Michaela
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Bäckvall, Jan-E.
    On the mechanism of the unexpected facile formation of meso-diacetate products in enzymatic acetylation of alkanediols2003Inngår i: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 68, s. 2216-2222Artikkel i tidsskrift (Fagfellevurdert)
  • 6.
    Eklund, Robert
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Widmalm, Göran
    Molecular dynamics simulations of an oligosaccharide using a force field modified for carbohydrates2003Inngår i: Carbohydrate Research, ISSN 0008-6215, Vol. 338, nr 5, s. 393-398Artikkel i tidsskrift (Fagfellevurdert)
  • 7.
    Franzén, Johan
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Bäckvall, Jan E.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Carbon-Carbon bond formation in Palladium(II)-Catalyzed Allylic Oxidation: A Novel Oxidative Carbozyclization of Allene-Substituted Olefins2003Inngår i: Journal of the American Chemical Society, ISSN 0002-7863, E-ISSN 1520-5126, Vol. 125, nr 20, s. 6056-6057Artikkel i tidsskrift (Fagfellevurdert)
  • 8.
    Franzén, Johan
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Löfstedt, Joakim
    Falk, Jennica
    Bäckvall, Jan-E
    Stereoselective Palladium-Catalyzed Carbocyclization of Allenic Allylic Carboxylates.2003Inngår i: Journal of the American Chemical Society, ISSN 0002-7863, E-ISSN 1520-5126, Vol. 125, nr 46, s. 14140-14148Artikkel i tidsskrift (Fagfellevurdert)
  • 9.
    Johansson, Olof
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Borgström, Magnus
    Lomoth, Reiner
    Palmblad, Magnus
    Bergquist, Jonas
    Hammarström, Leif
    Sun, Licheng
    Åkermark, Björn
    Electron Donor-Acceptor Dyads Based on Ruthenium(II) Bipyridine and Terpyridine Complexes Bound to Naphthalenediimide2003Inngår i: Inorganic Chemistry, ISSN 0020-1669, Vol. 42, nr 9, s. 2908-2918Artikkel i tidsskrift (Fagfellevurdert)
  • 10. Kapoor, Mili
    et al.
    Srinivas, Honnappa
    Kandiah, Eaazhisai
    Gemma, Emiliano
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Ellgaard, Lars
    Oscarson, Stefan
    Helenius, Ari
    Surolia, Avadhesha
    Interactions of Substrate with Calreticulin, an Endoplasmic Reticulum Chaperone2003Inngår i: Journal of Biological Chemistry, ISSN 0021-9258, E-ISSN 1083-351X, Vol. 278, nr 8, s. 6194–6200-Artikkel i tidsskrift (Fagfellevurdert)
  • 11.
    Lindén, Auri
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Krüger, Lars
    Bäckvall, Jan-Erling
    Highly Selective Sulfoxidation of Allylic and Vinylic Sulfides by Hydrogen Peroxide Using a Flavin as Catalyst2003Inngår i: Journal of Organic Chemistry, ISSN 0022-3263, Vol. 68, nr 15, s. 5890-5896Artikkel i tidsskrift (Fagfellevurdert)
  • 12. Lomoth, Reiner
    et al.
    Magnuson, Ann
    Xu, Yunhua
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Sun, Licheng
    Mixed-valence Properties of an Acetate-Bridged Dinuclear Ruthenium(II,III) Complex2003Inngår i: The Journal of Physical Chemistry A, ISSN 1089-5639, Vol. 107, nr 22, s. 4373-4380Artikkel i tidsskrift (Fagfellevurdert)
  • 13. Löfstedt, Joakim
    et al.
    Närhi, Katja
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Dorange, Ismet
    Bäckvall, Jan-E.
    Palladium-Catalyzed Carbocyclization of Allene-Diene derivatives. Exploring Different Nucleophiles.2003Inngår i: Journal of Organic Chemistry, ISSN 0022-3263, Vol. 68, nr 19, s. 7243-7248Artikkel i tidsskrift (Fagfellevurdert)
  • 14. Mohan, Halasayam
    et al.
    Gemma, Emiliano
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Ruda, Katinka
    Oscarson, Stefan
    Efficient Synthesis of Spacer-linked Dimers of N-Acetyllactosamine Using Microvawe-assisted Pyridinium Triflate-promoted Glycosylations with Oxazoline Donors2003Inngår i: Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry, ISSN 0936-5214, E-ISSN 1437-2096, nr 9, s. 1255-1256Artikkel i tidsskrift (Fagfellevurdert)
  • 15.
    Niclas, Solin
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Kjellgren, Johan
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Szabó, Kálmán J.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Palladium-Catalyzed Electrophilic Substitution via Monoallylpalladium Intermediates2003Inngår i: Angewandte Chemie International Edition, ISSN 1433-7851, E-ISSN 1521-3773, Vol. 42, nr 31, s. 3656-3658Artikkel i tidsskrift (Fagfellevurdert)
  • 16. Pastor, Isidro
    et al.
    Västilä, Patrik
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Adolfsson, Hans
    Employing the structural diversity of nature: Development of modular dipeptide-analogue ligands for ruthenium-catalyzed enantioselective transfer-hydrogenation of ketones2003Inngår i: Chemistry a European journal, ISSN 1521-3765, Vol. 9, nr 17, s. 4031-4045Artikkel i tidsskrift (Fagfellevurdert)
  • 17. Sebelius, Sara
    et al.
    Wallner, Olov
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Szabó, Kálmán J
    Palladium-Catalyzed Coupling of Allyl Acetates with Aldehyde and Imine Electrophiles in the Presence of Bis(pinacolato)diboron2003Inngår i: Organic Letters, ISSN 1523-7060, Vol. 5, nr 17, s. 3065-3068Artikkel i tidsskrift (Fagfellevurdert)
  • 18.
    Segerstedt, Eva
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Approaches to the synthesis of candidate glycoconjugate vaccines against non-typeable Haemophilus influenzae2003Doktoravhandling, med artikler (Annet vitenskapelig)
  • 19.
    Wallner, Olov
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Szabó, Kálmán J
    Origin of the Regio- and Stereoselectivity in Palladium-Catalyzed Electrophilic Substitution via Bis-allylpalladium Complexes2003Inngår i: Chemistry : a European journal, ISSN 0947-6539, Vol. 9, nr 17, s. 4025-4030Artikkel i tidsskrift (Fagfellevurdert)
  • 20.
    Wallner, Olov
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Szabó, Kálmán J
    Palladium-Catalyzed Electrophilic Allylic Substitution of Allyl Chlorides and Acetates via Bis-allylpalladium Intermediates2003Inngår i: Journal of Organic Chemistry, ISSN 0022-3263, Vol. 68, nr 7, s. 2934-2943Artikkel i tidsskrift (Fagfellevurdert)
  • 21.
    Wolpher, Henriette
    et al.
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Borgström, Magnus
    Hammarström, Leif
    Bergquist, Jonas
    Sundström, Villy
    Styring, Stenbjörn
    Sun, Licheng
    Åkermark, Björn
    Synthesis and Properties of an Iron Hydrogenase Active Site Model Linked to Ruthenium tris-Bipyridine Photosensitizer2003Inngår i: Inorganic Chemical Communications, Vol. 6, s. 989-991Artikkel i tidsskrift (Fagfellevurdert)
  • 22.
    Zmudzka, Katarzyna
    et al.
    Polish Acad Sci, Ctr Mol & Macromol Studies.
    Johansson, Tommy
    Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
    Wojcik, Marzena
    Polish Acad Sci, Ctr Mol & Macromol Studies.
    Janicka, Magdalena
    Polish Acad Sci, Ctr Mol & Macromol Studies.
    Nowak, Marian
    Polish Acad Sci, Ctr Mol & Macromol Studies.
    Stawinski, Jacek
    Nawrot, Barbara
    Polish Acad Sci, Ctr Mol & Macromol Studies.
    Novel DNA Analogues with 2-, 3- and 4-Pyridylphosphonate Internucleotide Bonds: Synthesis and Hybridisation Properties2003Inngår i: New Journal of Chemistry, ISSN 1144-0546, Vol. 27, nr 12, s. 1698-1705Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Oligothymidylates modified with stereodefined 2-pyridyl-, 3-pyridyl- and 4-pyridylphosphonate moieties at one or two juxtaposed internucleotide positions were prepared, and their avidity towards complementary single stranded DNA and RNA, as well as toward double stranded DNA were evaluated by UV melting temperature and CD studies. It was found that the sense of chirality at the phosphorus centre and the position of the nitrogen atom in the pyridyl ring of a pyridylphosphonate moiety are important factors governing stability of double- and triple-stranded complexes formed by these oligonucleotides. DNA/DNA and DNA/RNA duplexes containing oligothymidylate strands with R-P-pyridylphosphonate units differed only slightly from unmodified reference complexes. In contrast to this, the S-P-pyridylphosphonate derivatives exhibited lower binding affinity than both their R-P-counterparts and the unmodified reference oligonucleotide T-20. Triplexes of oligo(thymidyl pyridylphosphonate)s with hairpin oligomer d(A(21)C(4)T(21)) were found mostly to be thermodynamically slightly more stable in pH 7.4 and less stable in pH 5.0 than non-modified complexes. As expected, oligonucleotides with pyridylphosphonate internucleotide bonds were recognised by 3'- and 5'-exonucleases but the chimeric oligonucleotide chains were not cleaved at the modi. cation sites.

1 - 22 of 22
RefereraExporteraLink til resultatlisten
Permanent link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf