Combining a resonance and a Raman sensor: towards a new method for localizing prostate tumors in vivo
2007 (English)Report (Other academic)
Prostate cancer is the most common malignancy diagnosed in western men today. Measuring the amount of prostate-specific antigen in blood is the most widespread tool for diagnosing prostate cancer early on. However, clinical investigations show that many people with high levels of PSA can be healthy and vice versa. Ultrasound-guided biopsies is the clinical method used to prove prostate cancer. Unfortunately, many tumors are overlooked by this procedure. It has been estimated that about 30% of the biopsy examinations fail to find a present tumor. The resonance technique, which can differentiate hard and soft materials, has in vitro been shown to be able to distinguish prostate cancer and healthy epithelial prostate tissue. Raman spectroscopy is also a good candidate for detecting prostate cancer. Our novel idea of combining the resonance and Raman techniques into a portable probe, appropriate for in vivo examinations of the prostate, will be discussed in this report. The two techniques are presented and explained, and the feasibility of combining them is discussed. Planned experiments and investigations are outlined.
Place, publisher, year, edition, pages
Luleå: Luleå tekniska universitet, 2007. , 17 p.
Technical report / Luleå University of Technology, ISSN 1402-1536 ; 2007:15
Research subject Medical Engineering for Healthcare
IdentifiersURN: urn:nbn:se:ltu:diva-22635Local ID: 398b2f20-da1a-11dc-b464-000ea68e967bOAI: oai:DiVA.org:ltu-22635DiVA: diva2:995684
Godkänd; 2007; 20080213 (ysko)2016-09-292016-09-29Bibliographically approved