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Assessment of wear and periacetabular osteolysis using dual energy computed tomography on a pig cadaver to identify the lowest acceptable radiation dose
Karolinska Institute, Sweden.
Karolinska Institute, Sweden.
Karolinska Institute, Sweden; Karolinska University Hospital, Sweden.
Karolinska Institute, Sweden.
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2016 (English)In: BONE and JOINT RESEARCH, ISSN 2046-3758, Vol. 5, no 7, 307-313 p.Article in journal (Refereed) Published
Abstract [en]

Objectives Computed tomography (CT) plays an important role in evaluating wear and periacetabular osteolysis (PAO) in total hip replacements. One concern with CT is the high radiation exposure since standard pelvic CT provides approximately 3.5 millisieverts (mSv) of radiation exposure, whereas a planar radiographic examination with three projections totals approximately 0.5 mSv. The objective of this study was to evaluate the lowest acceptable radiation dose for dual-energy CT (DECT) images when measuring wear and periacetabular osteolysis in uncemented metal components. Materials and Methods A porcine pelvis with bilateral uncemented hip prostheses and with known linear wear and acetabular bone defects was examined in a third-generation multidetector DECT scanner. The examinations were performed with four different radiation levels both with and without iterative reconstruction techniques. From the high and low peak kilo voltage acquisitions, polychrmoatic images were created together with virtual monochromatic images of energies 100 kiloelectron volts (keV) and 150 keV. Results We could assess wear and PAO while substantially lowering the effective radiation dose to 0.7 mSv for a total pelvic view with an accuracy of around 0.5 mm for linear wear and 2 mm to 3 mm for PAO. Conclusion CT for detection of prosthetic wear and PAO could be used with clinically acceptable accuracy at a radiation exposure level equal to plain radiographic exposures.

Place, publisher, year, edition, pages
BRITISH EDITORIAL SOC BONE JOINT SURGERY , 2016. Vol. 5, no 7, 307-313 p.
Keyword [en]
Low-dose dual-energy computed tomography; Wear; Osteolysis; Accuracy
National Category
URN: urn:nbn:se:liu:diva-131188DOI: 10.1302/2046-3758.57.2000566ISI: 000380955700005PubMedID: 27445358OAI: diva2:971926
Available from: 2016-09-19 Created: 2016-09-12 Last updated: 2016-10-11

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Persson, Anders
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Division of Radiological SciencesFaculty of Medicine and Health SciencesDepartment of Radiology in LinköpingCenter for Medical Image Science and Visualization (CMIV)

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