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Optimisation of conductive polymer biomaterials for cardiac progenitor cells
Linköping University, Department of Physics, Chemistry and Biology, Biosensors and Bioelectronics. Linköping University, Faculty of Science & Engineering.
Linköping University, Department of Physics, Chemistry and Biology, Biosensors and Bioelectronics. Linköping University, Faculty of Science & Engineering.
Linköping University, Department of Clinical and Experimental Medicine, Division of Cell Biology. Linköping University, Faculty of Medicine and Health Sciences.
Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0001-6024-4144
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2016 (English)In: RSC Advances, ISSN 2046-2069, E-ISSN 2046-2069, Vol. 6, no 67, 62270-62277 p.Article in journal (Refereed) PublishedText
Abstract [en]

The characterisation of biomaterials for cardiac tissue engineering applications is vital for the development of effective treatments for the repair of cardiac function. New smart materials developed from conductive polymers can provide dynamic benefits in supporting and stimulating stem cells via controlled surface properties, electrical and electromechanical stimulation. In this study we investigate the control of surface properties of conductive polymers through a systematic approach to variable synthesis parameters, and how the resulting surface properties influence the viability of cardiac progenitor cells. A thorough analysis investigating the effect of electropolymerisation parameters, such as current density and growth, and reagent variation on physical properties provides a fundamental understanding of how to optimise conductive polymer biomaterials for cardiac progenitor cells.

Place, publisher, year, edition, pages
ROYAL SOC CHEMISTRY , 2016. Vol. 6, no 67, 62270-62277 p.
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Polymer Chemistry
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URN: urn:nbn:se:liu:diva-130451DOI: 10.1039/c6ra11682eISI: 000379678200028OAI: oai:DiVA.org:liu-130451DiVA: diva2:951151
Note

Funding Agencies|Linkoping University; IGEN (post-doc grant); COST-Action [MP1003]; Knut och Alice Wallenberg Commemorative Fund; European Research Agency

Available from: 2016-08-06 Created: 2016-08-05 Last updated: 2016-09-01

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Puckert, C.Gelmi, A.Kozak Ljunggren, MonikaRafat, MehrdadJager, Edwin
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Biosensors and BioelectronicsFaculty of Science & EngineeringDivision of Cell BiologyFaculty of Medicine and Health SciencesBiomedical Instrumentation
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