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Residential Risk Factors for Atopic Dermatitis in 3-to 6-Year Old Children: A Cross-Sectional Study in Shanghai, China
Fudan Univ, Shanghai Med Coll, Huashan Hosp, Dept Dermatol, Shanghai 200040, Peoples R China..
Fudan Univ, Shanghai Med Coll, Huashan Hosp, Dept Dermatol, Shanghai 200040, Peoples R China..
Fujian Med Univ, Dept Dermatol, Affiliated Hosp 1, Fuzhou 350000, Peoples R China..
Fudan Univ, Shanghai Med Coll, Huashan Hosp, Dept Dermatol, Shanghai 200040, Peoples R China..
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2016 (English)In: International Journal of Environmental Research and Public Health, ISSN 1661-7827, E-ISSN 1660-4601, Vol. 13, no 6, 537Article in journal (Refereed) Published
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Abstract [en]

Background: Atopic dermatitis (AD) is common among pre-school children in Shanghai. This study aimed to identify the risk factors for childhood AD from the perspectives of home environment, demographics and parents-grandparents' atopic disease. Methods: A cross-sectional study was conducted in Shanghai in April-June, 2010. Preschool children's parents or guardians were invited to participate a questionnaire survey in six districts (two urban and four suburban/rural) and 6624 children were finally recruited (51.3% boys). AD diagnosis was based on the U.K. Working Party's (UKWP) criteria. Adjusted odds ratios (AOR) with 95% confidence intervals (95% CI) were calculated by multiple logistic regression. Results: A total of 8.5% of children ever had AD. Around 10.2% of the mothers had lived in newly renovated/decorated homes (NRDH) during the prenatal period (one year before or during pregnancy) and 9.5% got new home furniture (NHF) during the same period. AD was more common in children when mothers had lived in NRDH homes during the prenatal period (AOR = 1.41; 95% CI 1.03-1.93), the current home had indoor mold (2.00, 1.48-2.70), parents-grandparents' had atopic diseases (3.85, 3.05-4.87), the children had food allergy (3.40, 2.63-4.40) or children lived in urban area (1.52, 1.18-1.96). Associations between AD and NRDH, NHF and indoor molds were only significant in children without parents-grandparents' atopic diseases. There was an interaction effect between parents-grandparents' atopic diseases and NRDH (p < 0.05). Conclusions: Home renovation/redecoration, new furniture and indoor mold, urban residency, heredity disposition and food allergy can be risk factors for childhood AD in Shanghai.

Place, publisher, year, edition, pages
2016. Vol. 13, no 6, 537
Keyword [en]
dermatology, home environment, redecoration, mold, dampness, urban residency, heredity
National Category
Dermatology and Venereal Diseases
Identifiers
URN: urn:nbn:se:uu:diva-299906DOI: 10.3390/ijerph13060537ISI: 000378860100016OAI: oai:DiVA.org:uu-299906DiVA: diva2:950356
Available from: 2016-07-29 Created: 2016-07-29 Last updated: 2017-11-28Bibliographically approved

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Norbäck, Dan

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