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Exploring linkage disequilibrium to date admixture using ancient DNA
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Plant Ecology and Evolution.
2016 (English)Independent thesis Advanced level (professional degree), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Admixture studies based on contemporary DNA are well studied and results from these have

shown to correlate well with other evidence. The study of using ancient DNA for determining

admixture times is a less explored alternative for determining admixture. Admixture-induced

Linkage Disequilibrium for Evolutionary Relationships (ALDER) is an established tool for

determining admixture time from contemporary DNA. This project investigates the use of

ALDER on simulated ancient DNA to determine if it can be used in actual ancient DNA

studies. The results from this project suggest that ALDER can be used in actual studies, with

good accuracy and reliability.

Place, publisher, year, edition, pages
UPTEC X, 16 001
National Category
Bioinformatics and Systems Biology
URN: urn:nbn:se:uu:diva-298198OAI: diva2:945151
Educational program
Molecular Biotechnology Engineering Programme
Available from: 2016-07-01 Created: 2016-06-30 Last updated: 2016-07-01Bibliographically approved

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fulltext(741 kB)13 downloads
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Plant Ecology and Evolution
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