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Mass Spectrometry Based Proteomics: Toward understanding neuropathic pain
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - BMC, Analytical Chemistry. Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - Ångström. Uppsala University, Disciplinary Domain of Science and Technology, Biology, Biology Education Centre.
2016 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

The aim of this project was to get insight into mass spectrometry based proteomics, get familiarized with novel techniques, and obtain the operating skills with modern Orbitrap mass spectrometers. In order to achieve this, the proteome changes in neuropathic pain responses corresponding to nerve injury side in individual rat’s spinal cord were explored. We focused in protein identification and quantification of the expressed proteins in 3 different set of samples, SNL, Sham and Naive rats. 

Place, publisher, year, edition, pages
2016.
Keyword [en]
neuropathic pain, mass spectrometry based proteomics, explorative proteomics
National Category
Analytical Chemistry
Identifiers
URN: urn:nbn:se:uu:diva-297658OAI: oai:DiVA.org:uu-297658DiVA: diva2:942733
Educational program
Master Programme in Applied Biotechnology
Supervisors
Available from: 2016-09-16 Created: 2016-06-26 Last updated: 2016-09-16Bibliographically approved

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fulltext(2402 kB)4 downloads
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Analytical ChemistryDepartment of Chemistry - ÅngströmBiology Education Centre
Analytical Chemistry

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