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Effekten av glukosmätningsmetoden FGM (LIBRE) på glukoskontrollen mätt som HbA1c i löpande diabetologisk rutinsjukvård
Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
2016 (Swedish)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
Abstract [sv]

Bakgrund: Diabetes mellitus typ 1 är en endokrin autoimmun sjukdom som kräver daglig insulinbehandling och en noggrann kontroll av blodglukoshalten. Sjukdomen medför en kroniskt hög blodglukoshalt som ligger till grund för diabeteskomplikationer senare i livet. Tidigare studier har visat god effekt av en intensivbehandling av diabetes mellitus för att reducera risken att drabbas av diabeteskomplikationer.

Syfte: Syftet med studien var att mäta effekten av glukosmätningsmetoden FGM (LIBRE) mätt som HbA1c i löpande diabetologisk rutinsjukvård.

Metod: Studien är en retrospektiv journalstudie som genomförts tillsammans med endokrinmottagningen på Ängelholms sjukhus.

Resultat: FreeStyle LIBRE glukosmätningsmetod leder via en intensivbehandling till förbättring av HbA1c hos de diabetespatienter med ett utgångs-HbA1c >62,4 mmol/mol. Patienter med ett utgångs-HbA1c på 70 mmol/mol reducerar med hjälp av FreeStyle LIBRE sitt HbA1c med 5 mmol/mol.

Slutsats: Ett utgångs-HbA1c >62,4 mmol/mol kommer med hjälp av FreeStyle LIBRE leda till en sänkning av HbA1c. Genom att sänka HbA1c reduceras risken att drabbas av de vanligaste diabeteskomplikationerna retinopati, nefropati, neuropati samt hjärt- och kärlsjukdomar. FreeStyle LIBRE ger goda förutsättningar för en reducering av diabeteskomplikationer för de patienter metoden ses vara effektiv för.

Abstract [en]

Background: Type 1 diabetes is an endocrine autoimmune disease that requires daily insulin therapy and careful monitoring of blood glucose. The disease causes a chronic high blood glucose level which is the basis of diabetes complications later in life. Previous studies have shown that intensive treatment of diabetes mellitus has a positive effect by reducing the risk of diabetes complications. 

Purpose: The aim of this study was to measure the effect of the glucose measurement method FGM (LIBRE) as measured by HbA1c at current diabetologic routine medical care.

Method: The study is a retrospective medical record study conducted together with endocrine recipiency at Ängelholms hospital.

Results: FreeStyle LIBRE glucose measurement method leads to improvement in HbA1c in diabetes patients with a baseline HbA1c >62,4 mmol/mol. Patients with a baseline HbA1c of 70 mmol/mol reducing their HbA1c with 5 mmol/mol by using FreeStyle LIBRE.

Conclusion: For diabetes patients with a baseline HbA1c >62,4 mmol/mol, use of FreeStyle LIBRE as part of an intensive treatment regime is likely to lead to a reduction in HbA1c. By lowering HbA1c and therby blood glucose levels, the risk for the most common diabetes complications retinopathy, nephropathy, neuropathy and cardiovascular diseases is likely to be reduced. 

Place, publisher, year, edition, pages
2016. , 25 p.
National Category
Medical and Health Sciences Other Health Sciences
Identifiers
URN: urn:nbn:se:lnu:diva-53602OAI: oai:DiVA.org:lnu-53602DiVA: diva2:937870
External cooperation
Endokrinmottagningen Ängelholms sjukhus
Subject / course
Biomedical Sciences
Educational program
Health Science Programme with Specialisation in Bio Sciences, 180 credits
Presentation
2016-05-26, 10:09 (Swedish)
Supervisors
Examiners
Available from: 2016-06-16 Created: 2016-06-16 Last updated: 2016-06-16Bibliographically approved

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