Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Association between neighbourhood air pollution concentrations and dispensed medication for psychiatric disorders in a large longitudinal cohort of Swedish children and adolescents
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine. (Umeå SIMSAM Lab ; Arcum)
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
Umeå University, Faculty of Social Sciences, Department of Geography and Economic History.
Show others and affiliations
2016 (English)In: BMJ Open, ISSN 2044-6055, E-ISSN 2044-6055, Vol. 6, no 6, e010004Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To investigate associations between exposure to air pollution and child and adolescent mental health.

DESIGN: Observational study.

SETTING: Swedish National Register data on dispensed medications for a broad range of psychiatric disorders, including sedative medications, sleeping pills and antipsychotic medications, together with socioeconomic and demographic data and a national land use regression model for air pollution concentrations for NO2, PM10 and PM2.5.

PARTICIPANTS: The entire population under 18 years of age in 4 major counties. We excluded cohort members whose parents had dispensed a medication in the same medication group since the start date of the register. The cohort size was 552 221.

MAIN OUTCOME MEASURES: Cox proportional hazards models to estimate HRs and their 95% CIs for the outcomes, adjusted for individual-level and group-level characteristics.

RESULTS: The average length of follow-up was 3.5 years, with an average number of events per 1000 cohort members of ∼21. The mean annual level of NO2 was 9.8 µg/m(3). Children and adolescents living in areas with higher air pollution concentrations were more likely to have a dispensed medication for a psychiatric disorder during follow-up (HR=1.09, 95% CI 1.06 to 1.12, associated with a 10 µg/m(3) increase in NO2). The association with NO2 was clearly present in 3 out of 4 counties in the study area; however, no statistically significant heterogeneity was detected.

CONCLUSION: There may be a link between exposure to air pollution and dispensed medications for certain psychiatric disorders in children and adolescents even at the relatively low levels of air pollution in the study regions. The findings should be corroborated by others.

Place, publisher, year, edition, pages
2016. Vol. 6, no 6, e010004
Keyword [en]
Epidemiology, Public health
National Category
Environmental Health and Occupational Health
Identifiers
URN: urn:nbn:se:umu:diva-121686DOI: 10.1136/bmjopen-2015-010004ISI: 000380237100010PubMedID: 27259522OAI: oai:DiVA.org:umu-121686DiVA: diva2:933626
Available from: 2016-06-07 Created: 2016-06-07 Last updated: 2017-11-30Bibliographically approved

Open Access in DiVA

fulltext(2696 kB)75 downloads
File information
File name FULLTEXT01.pdfFile size 2696 kBChecksum SHA-512
23d5a5c32e920625aed385fd5069ce393e66039fd86085f29da32a48d7973a9f379f7601127f87f8bce3368b2d6e1220eb4c7966b8a2f8fe72d656cc91ff7e7f
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Oudin, AnnaBråbäck, LennartOudin Åström, DanielStrömgren, MagnusForsberg, Bertil
By organisation
Occupational and Environmental MedicineDepartment of Geography and Economic History
In the same journal
BMJ Open
Environmental Health and Occupational Health

Search outside of DiVA

GoogleGoogle Scholar
Total: 75 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 146 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf