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Cornea Regeneration as an Alternative to Human Donor Transplantation
University of Montreal, Canada.
University of Ottawa Heart Institute, Canada.
Linköping University, Department of Clinical and Experimental Medicine, Division of Cell Biology. Linköping University, Faculty of Medicine and Health Sciences.ORCID iD: 0000-0003-1222-6720
2015 (English)In: European Ophthalmic Review, ISSN 1756-1795, Vol. 9, no 2, 111-114 p.Article in journal (Refereed) Published
Abstract [en]

There is a need for an alternative to human donor corneas as the availability of good-quality tissues remains limited, with this situation potentially worsening as the population in many countries is progressively ageing. There have been numerous attempts to develop corneal equivalent as alternatives to donated human corneas as well as prostheses. In this short review, we focus on the efforts in bioengineering implants that promote regeneration by Canadian researchers, including our current team of authors. The examples of technologies developed that we describe include biomaterials that allow for partial regeneration of corneal tissue, self-assembled cornea constructs and cell-free corneal implants that promoted regeneration when evaluated in clinical trials in Europe.

Place, publisher, year, edition, pages
touchOPHTHALMOLOGY.com , 2015. Vol. 9, no 2, 111-114 p.
Keyword [en]
Cornea, biomaterials, prostheses, regeneration, self-assembly, implants, clinical studies
National Category
Biomaterials Science
Identifiers
URN: urn:nbn:se:liu:diva-126611DOI: 10.17925/EOR.2015.09.02.111OAI: oai:DiVA.org:liu-126611DiVA: diva2:915882
Available from: 2016-03-31 Created: 2016-03-31 Last updated: 2016-04-20Bibliographically approved

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