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Impact evaluation and association with EuroQol 5D health-related utility values in Menieres disease
University of Tampere, Finland.
Linköping University, Department of Behavioural Sciences and Learning, Disability Research. Linköping University, Faculty of Arts and Sciences. Linköping University, The Swedish Institute for Disability Research. Lamar University, TX 77710 USA; Audiol India, India.
University of Helsinki, Finland.
University of Helsinki, Finland.
2015 (English)In: SPRINGER INTERNATIONAL PUBLISHING AG, GEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND, ISSN 2193-1801, Vol. 4, no 717Article in journal (Refereed) PublishedText
Abstract [en]

The study was aimed at evaluating the validity of impact measures among patients with Menieres disease (MD) with outcome variables of EuroQol generic health-related quality of life (HRQoL) measures (i.e., EQ-5D) by using Visual Analogue Scale (VAS) and EQ-5D index values. 183 members (out of 200 contacted) of the Finish Meniere Association returned the questionnaires that they had filled out. Various open-ended and structured questionnaires focusing on diagnostic aspects of symptoms and impairment caused by the disease were used. For activity limitation and participation restriction, standardized questionnaires were used. Open-ended questions on impact of the disease were asked, and subsequently classified based on the WHO-ICF classification. The general HRQoL was evaluated with EQ-5D index value and EQ VAS instruments. Correlation and linear regression analyses were used to explore the association between HRQoL and other aspects. Based on the explanatory power of different models the disease specific semeionic model provides the most accurate prediction in EQ-5D index calculations (38 % of the variance explained). In EQ VAS scores, HRQoL is most accurately determined by participation restriction (53 % of the variance explained), but the worst prediction was in ICF-based limitations (8 % of the variance explained). Interestingly, attitude and personal trait explained the reduction of HRQoL somewhat better than ICF-based variables. Activity limitation and participation restrictions are significant components of MD, but are less frequently recognized as significant factors in self-evaluating the effect of MD on the quality of life. The current study results suggest that MD patients seem to have problem identifying factors causing activity limitation and participation restrictions and hence use the semiotic description focusing on complaints.

Place, publisher, year, edition, pages
Keyword [en]
Menieres disease; Quality of life; EuroQol; EQ-5D; ICF; Activity limitations; Participation restrictions
National Category
Other Medical Sciences not elsewhere specified
URN: urn:nbn:se:liu:diva-125174DOI: 10.1186/s40064-015-1527-0ISI: 000368710400004PubMedID: 26636005OAI: diva2:903366

Funding Agencies|Finnish Slot Machine Association, RAY

Available from: 2016-02-15 Created: 2016-02-15 Last updated: 2016-03-08

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Manchaiah, Vinaya
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Disability ResearchFaculty of Arts and SciencesThe Swedish Institute for Disability Research
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