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The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study
Jonkoping Univ, Sch Hlth Sci, S-55111 Jonkoping, Sweden.;Karolinska Inst, Inst Environm Med, S-17177 Stockholm, Sweden..ORCID iD: 0000-0001-9042-4832
Jonkoping Univ, Sch Hlth Sci, S-55111 Jonkoping, Sweden..
Umea Univ, Dept Psychol, S-90187 Umea, Sweden.;Stockholm Univ, Stress Res Inst, S-10691 Stockholm, Sweden..
Jonkoping Univ, Sch Hlth Sci, S-55111 Jonkoping, Sweden.;Cty Hosp Ryhov, Dept Internal Med, S-55185 Jonkoping, Sweden..
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2015 (English)In: BioMed Research International, ISSN 2314-6133, E-ISSN 2314-6141, 371905Article in journal (Refereed) PublishedText
Abstract [en]

Introduction. Atrial fibrillation (AF) is a common heart rhythmdisorder. Several life-style factors have been identified as risk factors for AF, but less is known about the impact of work-related stress. This study aims to evaluate the association between work-related stress, defined as job strain, and risk of AF. Methods. Data from the Swedish WOLF study was used, comprising 10,121 working men and women. Job strain was measured by the demand-control model. Information on incident AF was derived from national registers. Cox proportional hazard regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for the association between job strain and AF risk. Results. In total, 253 incident AF cases were identified during a total follow-up time of 132,387 person-years. Job strain was associated with AF risk in a time-dependent manner, with stronger association after 10.7 years of follow-up (HR 1.93, 95% CI 1.10-3.36 after 10.7 years, versus HR 1.11, 95% CI 0.67-1.83 before 10.7 years). The results pointed towards a dose-response relationship when taking accumulated exposure to job strain over time into account. Conclusion. This study provides support to the hypothesis that work-related stress defined as job strain is linked to an increased risk of AF.

Place, publisher, year, edition, pages
2015. 371905
National Category
Public Health, Global Health, Social Medicine and Epidemiology
URN: urn:nbn:se:miun:diva-26520DOI: 10.1155/2015/371905ISI: 000364059500001ScopusID: 2-s2.0-84947232204OAI: diva2:882961
Available from: 2015-12-16 Created: 2015-12-16 Last updated: 2016-01-13Bibliographically approved

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