Episodic Learning and Memory in Prodromal Huntington’s Disease: The Role of Multimodal Encoding and Selective Reminding
2015 (English)In: International Journal of Clinical Medicine, ISSN 2158-284X, E-ISSN 2158-2882, Vol. 6, no 11, 876-886 p.Article in journal (Refereed) Published
This study investigated episodic memory in prodromal HD. Three groups were compared (N=70): mutation carriers with less than 12.5 years to disease onset (n=16), mutation carriers with 12.5 or more years to disease onset (n=16), and noncarriers (n=38). Episodic memory was assessed using the Fuld Object Memory Evaluation, which includes multimodal presentation and selective reminding, and the Claeson-Dahl Learning Test which includes verbal repeated presentation and recall trials. Both carrier groups demonstrated deficient episodic memory compared to noncarriers. The results suggest deficient episodic memory in prodromal HD, and that inconsistent retrieval contributes to these deficits. Multimodal presentation attenuates the deficits.
Place, publisher, year, edition, pages
2015. Vol. 6, no 11, 876-886 p.
Prodromal Huntington’s disease, Fuld Object Memory Evaluation, Episodic Memory, Short-Term Memory, Neurodegenerative Diseases
Gerontology, specializing in Medical and Health Sciences
IdentifiersURN: urn:nbn:se:hj:diva-28646DOI: 10.4236/ijcm.2015.611115Local ID: HHJÅldrandeISOAI: oai:DiVA.org:hj-28646DiVA: diva2:882791