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Genome-wide mapping of Painting of fourth on Drosophila melanogaster salivary gland polytene chromosomes
Umeå University, Faculty of Science and Technology, Department of Molecular Biology (Faculty of Science and Technology). (Jan Larsson)
Umeå University, Faculty of Science and Technology, Department of Molecular Biology (Faculty of Science and Technology). (Jan Larsson)
2014 (English)In: Genomics Data, ISSN 1025-6059, E-ISSN 2213-5960, Vol. 2, 63-65 p.Article in journal (Refereed) Published
Abstract [en]

The protein Painting of fourth (POF) in Drosophila melanogaster specifically targets and stimulates expression output from the heterochromatic 4th chromosome, thereby representing an autosome specific protein [1,2]. Despite the high specificity for chromosome 4 genes, POF is occasionally observed binding to the cytological region 2L:31 in males and females [3] and two loci on the X-chromosome, PoX1 and PoX2 only in females [4]. Here we provide a detailed description of the experimental design and analysis of the tiling array data presented by Lundberg and colleagues in G3: Genes, Genomes, Genetics 2013 [4], where the female specific POF binding to PoX1 and PoX2 loci on the X chromosome was reported. We show the genome-wide high resolution binding profile of the POF protein where these different POF binding sites are detected. The complete data set is available at http://www.ncbi.nlm.nih.gov/geo/ (accession: GSE45402).

Place, publisher, year, edition, pages
2014. Vol. 2, 63-65 p.
Keyword [en]
Painting of fourth, Drosophila melanogaster, ChIP-chip
National Category
Genetics
Research subject
Genetics
Identifiers
URN: urn:nbn:se:umu:diva-112366DOI: 10.1016/j.gdata.2014.04.007PubMedID: 26484072OAI: oai:DiVA.org:umu-112366DiVA: diva2:877325
Available from: 2015-12-07 Created: 2015-12-07 Last updated: 2017-12-01Bibliographically approved

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