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The influence of age, gender, insulin dose, BMI, and blood pressure on metabolic control in young patients with type 1 diabetes
Ryhov County Hospital, Sweden; Jonköping County Council, Sweden; University of Jonköping, Sweden.
Linköping University, Department of Medical and Health Sciences, Division of Nursing Science. Linköping University, Faculty of Medicine and Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center of Paediatrics and Gynaecology and Obstetrics, Department of Paediatrics in Linköping.
2015 (English)In: Pediatric Diabetes, ISSN 1399-543X, E-ISSN 1399-5448, Vol. 16, no 8, 581-586 p.Article in journal (Refereed) Published
Abstract [en]

ObjectiveTo explore the relationship between certain clinical variables and metabolic HbA1c at diagnosis correlated to HbA1c at follow-up (p less than 0.001). There was a clear gender difference regarding HbA1c. Girls had higher values both at diagnosis and at follow-up (p less than 0.001). Girls also had lower BMI and pH at diagnosis than boys (p less than 0.001). In contrast, girls with the highest body mass index (BMI) at follow-up had higher mean HbA1c at follow-up in 2010 (p less than 0.001). Having a mother and/or a father with high BMI implied higher HbA1c at diagnosis (p less than 0.003). ConclusionsHbA1c at diagnosis seems to predict metabolic control years later. There is a gender difference at diagnosis as female patients have higher HbA1c than males at diagnosis as well as at follow up. As metabolic control is very much correlated to complications there is a need to early identify patients at risk of poor metabolic control. Even though we do not know whether a high HbA1c level is mainly due to severity of the disease or to behavioral patterns, new ways to treat and support these children, especially girls, are needed.

Place, publisher, year, edition, pages
WILEY-BLACKWELL , 2015. Vol. 16, no 8, 581-586 p.
Keyword [en]
children; gender; HbA1c; metabolic control; quality register; type 1 diabetes
National Category
Clinical Medicine
URN: urn:nbn:se:liu:diva-123060DOI: 10.1111/pedi.12219ISI: 000363929400003PubMedID: 25270077OAI: diva2:876660

Funding Agencies|Ostergotland County Council; academy for Health and Care; Jonkoping County Council; Futurum

Available from: 2015-12-04 Created: 2015-12-03 Last updated: 2016-03-09

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Hanberger, LenaSamuelsson, Ulf
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