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Twenty-one days of isolation: A prospective observational cohort study of an Ebola-exposed hot zone community in Liberia
World Health Organization, Liberia Mission, Liberia .
World Health Organization, Liberia Mission, Liberia .
Ministry of Health & Social Welfare, Liberia .
African Union-ASEOWA Liberia, Liberia .
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2015 (English)In: Journal of Infection, ISSN 0163-4453, E-ISSN 1532-2742, Vol. 71, no 2, 150-7 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: As West Africa continues to suffer from a deadly Ebola epidemic, the national health sectors struggle to minimize the damages and stop the spread of disease.

METHODS: A cohort of inhabitants of a small village and an Ebola hot zone in Sinoe County of Liberia was followed on a day-by-day basis to search for new cases and to minimize the spread of Ebola to the other community members or to other regions. Technical, clinical, and humanistic aspects of the response are discussed in this report.

RESULTS: Of the 22 confirmed Ebola cases in Sinoe County since the beginning of outbreak (June 16, 2014), 7 cases were inhabitants of Polay Town, a small village 5.5 miles east of Greenville, the Sinoe County capital. After the last wave of outbreak at the beginning of December, enhanced response activity provided essential coordination and mobilized the resources to stop the epidemic. Despite unprotected contacts in crowded houses, no new cases were detected among the contact families, or in the surrounding houses or communities.

CONCLUSIONS: Strong national mobilization in a decentralized but harmonized system at the community level has been of great value in controlling the epidemic in Liberia. The major interventions include epidemiological surveillance, public information dissemination, effective communication, case management, and infection control.

Place, publisher, year, edition, pages
2015. Vol. 71, no 2, 150-7 p.
National Category
Infectious Medicine
URN: urn:nbn:se:liu:diva-120614DOI: 10.1016/j.jinf.2015.05.003ISI: 000365137700002PubMedID: 25982026OAI: diva2:846969
Available from: 2015-08-18 Created: 2015-08-18 Last updated: 2015-12-21

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Nayeri, Fariba
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Division of Microbiology and Molecular MedicineFaculty of Medicine and Health SciencesDepartment of Infectious Diseases
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