Change search
ReferencesLink to record
Permanent link

Direct link
Do non-communicable diseases such as hypertension and diabetes associate with primary open-angle glaucoma?: Insights from a case-control study in Nepal
Nepal Medical College Teaching Hospital, Kathmandu, Nepal / Nordic School of Public Health NHV, Gothenburg, Sweden.
Nordic School of Public Health NHV, Gothenburg, Sweden / Kathmandu Medical College, Kathmandu, Nepal.
B.P. Eye Foundation, Kathmandu, Nepal.
Nordic School of Public Health NHV, Gothenburg, Sweden / Sahlgrenska Academy at University of Gothenburg, Sweden.ORCID iD: 0000-0002-4583-9315
2013 (English)In: Global Health Action, ISSN 1654-9880, E-ISSN 1654-9880, Vol. 6, 22636- p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Non-communicable diseases (NCDs) such as hypertension and diabetes are rapidly emerging public health problems worldwide, and they associate with primary open-angle glaucoma (POAG). POAG is the most common cause of irreversible blindness. The most effective ways to prevent glaucoma blindness involve identifying high-risk populations and conducting routine screening for early case detection. This study investigated whether POAG associates with hypertension and diabetes in a Nepalese population.

METHODS: To explore the history of systemic illness, our hospital-based case-control study used non-random consecutive sampling in the general eye clinics in three hospitals across Nepal to enroll patients newly diagnosed with POAG and controls without POAG. The study protocol included history taking, ocular examination, and interviews with 173 POAG cases and 510 controls. Data analysis comprised descriptive and inferential statistics. Descriptive statistics computed the percentage, mean, and standard deviation (SD); inferential statistics used McNemar's test to measure associations between diseases.

RESULTS: POAG affected males more frequently than females. The odds of members of the Gurung ethnic group having POAG were 2.05 times higher than for other ethnic groups. Hypertension and diabetes were strongly associated with POAG. The overall odds of POAG increased 2.72-fold among hypertensive and 3.50-fold among diabetic patients.

CONCLUSION: POAG associates significantly with hypertension and diabetes in Nepal. Thus, periodic glaucoma screening for hypertension and diabetes patients in addition to opportunistic screening at eye clinics may aid in detecting more POAG cases at an early stage and hence in reducing avoidable blindness.

Place, publisher, year, edition, pages
CoAction Publishing, 2013. Vol. 6, 22636- p.
Keyword [en]
blindness, diabetes mellitus, hypertension, non-communicable disease (NCD), primary open-angle glaucoma (POAG)
National Category
Public Health, Global Health, Social Medicine and Epidemiology
URN: urn:nbn:se:his:diva-11348DOI: 10.3402/gha.v6i0.22636PubMedID: 24192283OAI: diva2:846444
Available from: 2015-08-17 Created: 2015-08-17 Last updated: 2016-04-12Bibliographically approved

Open Access in DiVA

fulltext(91 kB)114 downloads
File information
File name FULLTEXT01.pdfFile size 91 kBChecksum SHA-512
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Krettek, Alexandra
In the same journal
Global Health Action
Public Health, Global Health, Social Medicine and Epidemiology

Search outside of DiVA

GoogleGoogle Scholar
Total: 114 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 290 hits
ReferencesLink to record
Permanent link

Direct link