Metal-Free N-Arylation of Secondary Amides at Room Temperature
Number of Authors: 5
2015 (English)In: Organic Letters, ISSN 1523-7060, E-ISSN 1523-7052, Vol. 17, no 11, 2688-2691 p.Article in journal (Refereed) Published
The arylation of secondary acyclic amides has been achieved with diaryliodonium salts under mild and metal-free conditions. The methodology has a wide scope, allows synthesis of tertiary amides with highly congested aryl moieties, and avoids the regioselectivity problems observed in reactions with (diacetoxyiodo)benzene.
Place, publisher, year, edition, pages
2015. Vol. 17, no 11, 2688-2691 p.
IdentifiersURN: urn:nbn:se:su:diva-119153DOI: 10.1021/acs.orglett.5b01079ISI: 000355962200032OAI: oai:DiVA.org:su-119153DiVA: diva2:845575