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First evidence of Seoul hantavirus in the wild rat population in the Netherlands
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology. (Åke Lundkvist)ORCID iD: 0000-0002-0467-944X
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2015 (English)In: Infection Ecology & Epidemiology, ISSN 2000-8686, E-ISSN 2000-8686, Vol. 5, 27215- p.Article in journal (Refereed) Published
Abstract [en]

We report the first detection of Seoul hantavirus (SEOV)-specific antibodies in the wild brown rat population in the Netherlands. SEOV-reactive antibodies were found in three rats out of 16 in a repeated series of tests including immunofluorescence assay, immunoblot, and enzyme-linked immunosorbent assay. Focus reduction neutralization test confirmed the presence of SEOV-specific antibodies, and reverse-transcription polymerase chain reaction (RT-PCR) confirmed the presence of hantaviral RNA. This discovery follows the recent findings of SEOV infections in wild and pet brown rats and humans in England, Wales, France, Belgium, and Sweden, indicating an even higher importance of this hantavirus for public health in large areas of Europe.

Place, publisher, year, edition, pages
2015. Vol. 5, 27215- p.
National Category
Infectious Medicine
Identifiers
URN: urn:nbn:se:uu:diva-254988DOI: 10.3402/iee.v5.27215PubMedID: 25656468OAI: oai:DiVA.org:uu-254988DiVA: diva2:821256
Available from: 2015-06-15 Created: 2015-06-12 Last updated: 2017-12-04Bibliographically approved

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