Mechanism of palladium/amine cocatalyzed carbocyclization of aldehydes with alkynes and its merging with "Pd oxidase catalysis"
2014 (English)In: ACS Catalysis, ISSN 2155-5435, E-ISSN 2155-5435, Vol. 4, no 12, 4474-4484 p.Article in journal (Refereed) Published
The reaction mechanism for the palladium and amine cocatalyzed carbocyclization of aldehydes with alkynes has been investigated by means of density functional theory calculations and experiments. The Pd/amine cocatalyzed transformation is a carbocyclization of in situ generated enaminynes where the C-C bond-forming step is most likely promoted by a Pd(II) species. Notably, the latent Pd(0)/Pd(II) catalytic redox cycle of this metal/organo cooperative catalytic reaction can be merged with catalytic direct aerobic alcohol oxidation (Pd oxidase catalysis). (Chemical Equation Presented).
Place, publisher, year, edition, pages
2014. Vol. 4, no 12, 4474-4484 p.
Carbocyclization, Density functional theory, Multicatalysis, Oxidations, Oxygen, Relay catalysis
IdentifiersURN: urn:nbn:se:miun:diva-24072DOI: 10.1021/cs500905rISI: 000346041600030ScopusID: 2-s2.0-84915793230OAI: oai:DiVA.org:miun-24072DiVA: diva2:777026
CODEN: ACCAC2015-01-082015-01-072016-12-01Bibliographically approved