Interference-Free Electrochemical Detection of Nanomolar Dopamine Using Doped Polypyrrole and Silver Nanoparticles
2014 (English)In: Electroanalysis, ISSN 1040-0397, E-ISSN 1521-4109, Vol. 26, no 10, 2197-2206 p.Article in journal (Refereed) Published
This paper presents a new approach to detect dopamine in nanomolar range using an electrochemical sensor utilizing a composite made of chitosan-stabilized silver nanoparticles and p-toluene sulfonic acid-doped ultrathin polypyrrole film. Studies included cyclic voltammogram, amperometry, differential pulse voltammetry and also investigation by electrochemical impedance spectroscopy. A detection limit of 0.58 nM was achieved in the linear range 1 x 10(-9) M to 1.2 x 10(-7) M. High sensitivity towards DA, good reproducibility and long-term stability have been demonstrated without interference from ascorbic acid, uric acid, epinephrine, l-dopa, glucose. The sensing system was successfully applied for quantitative determination of dopamine in commercially available human blood serum.
Place, publisher, year, edition, pages
Wiley-VCH Verlag , 2014. Vol. 26, no 10, 2197-2206 p.
Dopamine; Polypyrrole; Silver nanoparticles; Selectivity; Impedance
IdentifiersURN: urn:nbn:se:liu:diva-112650DOI: 10.1002/elan.201400332ISI: 000343927400016OAI: oai:DiVA.org:liu-112650DiVA: diva2:768940
Funding Agencies|DST (INSPIRE), New Delhi2014-12-052014-12-052014-12-17