Change search
ReferencesLink to record
Permanent link

Direct link
Environmentally relevant concentrations of citalopram partially inhibit feeding in the three-spine stickleback (Gasterosteus aculeatus)
Södertörn University, School of Natural Sciences, Technology and Environmental Studies, Environmental Science.ORCID iD: 0000-0002-0856-9707
Södertörn University, School of Natural Sciences, Technology and Environmental Studies, Environmental Science.
Södertörn University, School of Natural Sciences, Technology and Environmental Studies, Biology.ORCID iD: 0000-0001-9498-3033
Univ. of Copenhagen.
Show others and affiliations
2015 (English)In: Aquatic Toxicology, ISSN 0166-445X, E-ISSN 1879-1514, Vol. 158, 165-170 p.Article in journal (Refereed) Published
Abstract [en]

Selective Serotonin Re-uptake Inhibitors (SSRI) are mood-altering, psychotropic drugs commonly used in the treatment of depression and other psychological illnesses. Many of them are poorly degraded in sewage treatment plants and enter the environment unaltered. In laboratory studies, they have been demonstrated to affect a wide range of behaviours in aquatic organisms. In this study we investigated the effect of a three-week exposure to 0.15 and 1.5 μg/l of the SSRI citalopram dissolved in the ambient water on the feeding behaviour in three-spine stickleback (Gasterosteus aculeatus). Feeding, measured as the number of attacks performed on a piece of frozen bloodworms during a 10-min period, was reduced by 30–40% in fish exposed to both 0.15 and 1.5 μg/l citalopram. The effects of the environmentally relevant concentration 0.15 μg/l on feeding, an important fitness characteristic, suggests that the ecological significance of environmental SSRI exposure may be pronounced.

Place, publisher, year, edition, pages
Elsevier, 2015. Vol. 158, 165-170 p.
Keyword [en]
SSRI, citalopram, fish, stickleback, feeding, antidepressant
National Category
Environmental Sciences
Research subject
Environmental Studies
Identifiers
URN: urn:nbn:se:sh:diva-25351DOI: 10.1016/j.aquatox.2014.11.003ISI: 000348888400018PubMedID: 25438122ScopusID: 2-s2.0-84912082657OAI: oai:DiVA.org:sh-25351DiVA: diva2:767709
Funder
The Foundation for Baltic and East European Studies
Available from: 2014-12-02 Created: 2014-12-02 Last updated: 2016-12-01Bibliographically approved

Open Access in DiVA

fulltext(343 kB)2 downloads
File information
File name FULLTEXT01.pdfFile size 343 kBChecksum SHA-512
07536a216865a1561745f3a3505d43b2a130979b69c836cce9a43e1b591c56b145b0ee613b71ec164658579ed7de8ab03c9ecacbd82fdec00bb0464edfcdc6f0
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Search in DiVA

By author/editor
Kellner, MartinPorseryd, TovePorsch-Hällström, IngerOlsén, K. Håkan
By organisation
Environmental ScienceBiology
In the same journal
Aquatic Toxicology
Environmental Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 2 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 200 hits
ReferencesLink to record
Permanent link

Direct link