Change search
ReferencesLink to record
Permanent link

Direct link
Synthesis of highly substituted dienes via silaboration and crosscouplingreactions
KTH, School of Chemical Science and Engineering (CHE).
2012 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

A synthetic approach to highly substituted dienes has been investigated. In a four step

synthesis, a wide range of molecules can be formed: Sonogashira coupling between an

alkyne and a bromoalkene, silaboration of the newly formed enyne, Suzuki‐Miyaura

coupling to exchange the boronic ester moiety, and silver(I) oxide activated crosscoupling

to replace the silicon atom. The majority of final compounds are afforded in

moderate to good yields (20‐55% over 4 steps). In some cases, the last step where the

silyl moiety is exchanged to an aromatic ring has caused some problems: isomerization

and lower yields.

Place, publisher, year, edition, pages
2012. , 49 p.
National Category
Engineering and Technology
URN: urn:nbn:se:kth:diva-156208OAI: diva2:765776
Available from: 2014-11-25 Created: 2014-11-25 Last updated: 2014-11-25Bibliographically approved

Open Access in DiVA

fulltext(18859 kB)63 downloads
File information
File name FULLTEXT01.pdfFile size 18859 kBChecksum SHA-512
Type fulltextMimetype application/pdf

By organisation
School of Chemical Science and Engineering (CHE)
Engineering and Technology

Search outside of DiVA

GoogleGoogle Scholar
Total: 63 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 18 hits
ReferencesLink to record
Permanent link

Direct link