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Cutoff sample size estimation for survival data: a simulation study
Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Statistics.
2014 (English)Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

This thesis demonstrates the possible cutoff sample size point that balances goodness of es-timation and study expenditure by a practical cancer case. As it is crucial to determine the sample size in designing an experiment, researchers attempt to find the suitable sample size that achieves desired power and budget efficiency at the same time. The thesis shows how simulation can be used for sample size and precision calculations with survival data. The pre-sentation concentrates on the simulation involved in carrying out the estimates and precision calculations. The Kaplan-Meier estimator and the Cox regression coefficient are chosen as point estimators, and the precision measurements focus on the mean square error and the stan-dard error.

Place, publisher, year, edition, pages
2014. , 33 p.
Keyword [en]
sample size, simulation, survival analysis
National Category
Probability Theory and Statistics
URN: urn:nbn:se:uu:diva-234982OAI: diva2:758585
Subject / course
Educational program
Master Programme in Statistics
Available from: 2014-11-17 Created: 2014-10-27 Last updated: 2014-11-17Bibliographically approved

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Department of Statistics
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