Aerosol sampling using an electrostatic precipitator integrated with a microfluidic interface
2015 (English)In: Sensors and actuators. B, Chemical, ISSN 0925-4005, Vol. 212, 344-352 p.Article in journal (Refereed) Published
In this work, the development of a point-of-care (PoC) system to capture aerosol from litres of air directly onto a microfluidic lab-on-chip for subsequent analysis is addressed. The system involves an electrostatic precipitator that uses corona charging and electrophoretic transport to capture aerosol droplets onto a microfluidic air-to-liquid interface for downstream analysis. A theoretical study of the governing geometric and operational parameters for optimal electrostatic precipitation is presented. The fabrication of an electrostatic precipitator prototype and its experimental validation using a laboratory-generated aerosolized dye is described. Collection efficiencies were comparable to those of a state-of-the-art Biosampler impinger, with the significant advantage of providing samples that are at least 10 times more concentrated. Finally, we discuss the potential of such a system for breath-based diagnostics.
Place, publisher, year, edition, pages
Elsevier, 2015. Vol. 212, 344-352 p.
breath analysis, poc, point-of-care, lab-on-chip, loc, microfluidics, aerosol, sampling, medical device, diagnostics, electrostatic precipitation, corona discharge
Other Electrical Engineering, Electronic Engineering, Information Engineering Other Medical Biotechnology
Research subject Electrical Engineering
IdentifiersURN: urn:nbn:se:kth:diva-144986DOI: 10.1016/j.snb.2015.02.008ISI: 000351017700043ScopusID: 2-s2.0-84923763722OAI: oai:DiVA.org:kth-144986DiVA: diva2:715441
QC 201502232014-05-052014-05-052015-04-29Bibliographically approved