The levels of five perfluoroalkylated (PFA) compounds, PFOS, PFOA, PFHxS, PFOSA and
PFNA were determined in whole blood and plasma from 47 males and 36 females
representing the Swedish population. The analytical method developed and used includes
solid-phase extraction and liquid chromatography electrospray masspectrometry. PFOS was
the PFA found at the highest concentration in whole blood (18.2 pg/ul) followed by PFOSA
(4.1 pg/μl), PFOA (2.7 pg/μl), PFHxS (2.3 pg/μl) and PFNA (0.3 pg/μl). Besides the five
compounds determined, we were able to detect PFHxA, PFDA, PFDS, PFUnDA, PFDoDA
and PFTDA in some of the samples/at low concentrations, the only compound included in this
study that we did not detect was PFBuS. This shows that the Swedish population are exposed
for a large number of PFAs. The concentrations of PFOS and PFOA correspond to those
found in USA. The correlation between PFOS and the other compounds was studied in order
to find out if there is a common source of exposure. Only a very week correlation between
PFOS and PFOA could be seen.
2004. , 16 p.