Change search
ReferencesLink to record
Permanent link

Direct link
WINROP identifies severe retinopathy of prematurity at an early stage in a nation-based cohort of extremely preterm infants.
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Paediatrics.
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Paediatrics.
Show others and affiliations
2013 (English)In: PLoS ONE, ISSN 1932-6203, Vol. 8, no 9, e73256- p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To evaluate the ability of a postnatal weight-gain algorithm (WINROP) to identify sight-threatening retinopathy of prematurity (ROP type 1) in a nation-based extremely preterm infant cohort.

METHODS: This study enrolled all 707 live-born extremely preterm (gestational age [GA] <27 weeks) infants, born 2004-2007 in Sweden; the Extremely preterm Infants in Sweden Study (EXPRESS). WINROP analysis was performed retrospectively in 407 of the infants using weekly weight gain to assess the preterm infant's risk of developing ROP type 1 requiring treatment. GA, birthweight (BW), and weekly postnatal weight measurements were entered into WINROP. WINROP signals with an alarm to indicate if the preterm infant is at risk for ROP type 1.

RESULTS: In this extremely preterm population, WINROP correctly identified 96% (45/47) of the infants who required treatment for ROP type 1. The median time from alarm to treatment was 9 weeks (range, 4-20 weeks).

CONCLUSIONS: WINROP, an online surveillance system using weekly weight gain, identified extremely preterm infants at risk for ROP type 1 requiring treatment at an early stage and with high sensitivity in a Swedish nation-based cohort.

Place, publisher, year, edition, pages
Public Library of Science, PLoS , 2013. Vol. 8, no 9, e73256- p.
National Category
Research subject
URN: urn:nbn:se:umu:diva-83483DOI: 10.1371/journal.pone.0073256PubMedID: 24069180OAI: diva2:667609
Vinnova, 2009-01152, 2009-00221Swedish Research Council, 2008-2842, 2011-2432
Available from: 2013-11-27 Created: 2013-11-27 Last updated: 2013-12-04Bibliographically approved

Open Access in DiVA

fulltext(478 kB)58 downloads
File information
File name FULLTEXT01.pdfFile size 478 kBChecksum SHA-512
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Stoltz Sjöström, ElisabethDomellöf, Magnus
By organisation
In the same journal

Search outside of DiVA

GoogleGoogle Scholar
Total: 58 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 65 hits
ReferencesLink to record
Permanent link

Direct link