Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Pelvic organ prolapse after subtotal and total hysterectomy: a long-term follow-up of an open randomised controlled multicentre study
Uppsala University, Sweden.
Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Center of Paediatrics and Gynaecology and Obstetrics, Department of Gynaecology and Obstetrics in Linköping.
Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Center of Paediatrics and Gynaecology and Obstetrics, Department of Gynaecology and Obstetrics in Linköping.
2013 (English)In: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 120, no 12, 1556-1565 p.Article in journal (Refereed) Published
Abstract [en]

Objective

To analyse the development of pelvic organ prolapse (POP) after subtotal (SH) and total hysterectomy (TH) in the long-term, and to assess patient-reported symptoms regarding pelvic floor dysfunction (PFD).

Design

Long-term follow-up study of a randomised controlled multicentre study.

Setting

Seven hospitals and one private clinic in the south-east of Sweden.

Population

Of the 184 women who were eligible from the original trial, 151 (82%) responded to a postal questionnaire and 128 (70%) were clinically examined.

Methods

Postal questionnaire using the short-form version of the Pelvic Floor Distress Inventory (PFDI-20) and clinical examination using the POP-Q system. Multivariate analyses were used.

Main outcome measures

POP-Q measurements and symptoms of PFD.

Results

Follow-up time was a median of 11.3 years. Less than 3% had stage-3 prolapse. No significant difference was found in the presence of stage-2 or higher stage prolapse between the two hysterectomy groups (39% in SH versus 37% in TH; OR 1.28, 95% CI 0.59–2.80). Nor was there any significant difference in the quality-of-life measurement between the SH and TH groups [summary score PFDI-20: median 93 (range 60–201) versus 87 (range 60–186); Fisher's protected least significant difference post hoc test, = 0.78 ). None of the symptoms of PFD revealed statistically significant differences between the hysterectomy groups.

Conclusions

This long-term follow-up study of PFD showed basically no significant differences in subjective or objective measurements of POP, or in specific pelvic floor quality-of-life aspects after SH and TH. However, because of the low statistical power the results are inconclusive. Larger trials, and probably also a longer follow-up period, are necessary.

Place, publisher, year, edition, pages
Wiley-Blackwell , 2013. Vol. 120, no 12, 1556-1565 p.
Keyword [en]
Hysterectomy, long-term follow-up, pelvic organ prolapse, pelvic organ prolapse-quantification, randomised trial
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-100471DOI: 10.1111/1471-0528.12399ISI: 000325627200015OAI: oai:DiVA.org:liu-100471DiVA: diva2:662994
Note

Funding Agencies|Medical Research Council of South East Sweden||County Council of Ostergotland||Linkoping University||

Available from: 2013-11-08 Created: 2013-11-08 Last updated: 2017-12-06

Open Access in DiVA

fulltext(449 kB)598 downloads
File information
File name FULLTEXT01.pdfFile size 449 kBChecksum SHA-512
f08210350cad4d04ac53b7a97c8dc03af013deddab50490211faab648d091c3cbe1b681c3d465c55327cd7f8dccea65454c4b04d331452f7636f3eac7059c667
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Brynhildsen, JanKjölhede, Preben
By organisation
Division of Clinical SciencesFaculty of Health SciencesDepartment of Gynaecology and Obstetrics in Linköping
In the same journal
British Journal of Obstetrics and Gynecology
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 598 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 93 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf