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Integrated treatment vs. treatment-as-usual for recent onset schizophrenia; 12 year follow-up on a randomized controlled trial
Norwegian University of Science and Technology, Faculty of Medicine, Department of Neuroscience. PH - Nidaros distriktspsykiatriske senter - St Olavs Hospital HF.
Helse Midt-Norge .
Norwegian University of Science and Technology, Faculty of Medicine, Department of Neuroscience. PH - Divisjonsstab Psykisk Helsevern - St Olavs Hospital HF.
2013 (English)In: BMC Psychiatry, ISSN 1471-244X, Vol. 13:200, -8 p.Article in journal (Refereed) Published
Abstract [en]

Background: The aim of this study is to compare the 12-year follow-up effects on in- and outpatient services of 2 years of integrated treatment for recent-onset schizophrenia versus treatment as usual in a randomized controlled trial.

Methods: 50 patients aged 18–35 years were randomized to Integrated Treatment (IT) (N = 30) or Treatment-as-Usual (TAU) (N = 20) for two years. TAU comprised optimal pharmacotherapy and outreach assertive treatment, while IT also included cognitive-behavioural family treatment, skills training, strategies for residual psychotic and non-psychotic problems and home-based crisis management.

Results: There were no differences in number of days in hospital, time to readmission, number of admittances to psychiatric wards, number of involuntarily psychiatric admissions or number of outpatient contacts over a period of 12 years following the initial 2-year treatment trial. Fewer patients in the IT group were, however, involuntary admitted to hospital in the period.

Conclusions: The intensive two-year psychosocial intervention seemed to have little long-term effects on use of in- and outpatient services.

Place, publisher, year, edition, pages
BioMed Central, 2013. Vol. 13:200, -8 p.
URN: urn:nbn:no:ntnu:diva-23180DOI: 10.1186/1471-244X-13-200OAI: diva2:658853

© 2013 Sigrúnarson et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available from: 2013-10-23 Created: 2013-10-23 Last updated: 2013-10-23

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