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New Photoplethysmographic Signal Analysis Algorithm for Arterial Stiffness Estimation
Tallinn University of Technology, Estonia .
Tallinn University of Technology, Estonia .
Tallinn University of Technology, Estonia .
Linköping University, Department of Biomedical Engineering, Physiological Measurements. Linköping University, The Institute of Technology.
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2013 (English)In: Scientific World Journal, ISSN 1537-744X, Vol. 2013Article in journal (Refereed) Published
Abstract [en]

The ability to identify premature arterial stiffening is of considerable value in the prevention of cardiovascular diseases. The "ageing index" (AGI), which is calculated from the second derivative photoplethysmographic (SDPPG) waveform, has been used as one method for arterial stiffness estimation and the evaluation of cardiovascular ageing. In this study, the new SDPPG analysis algorithm is proposed with optimal filtering and signal normalization in time. The filter parameters were optimized in order to achieve the minimal standard deviation of AGI, which gives more effective differentiation between the levels of arterial stiffness. As a result, the optimal low-pass filter edge frequency of 6 Hz and transitionband of 1 Hz were found, which facilitates AGI calculation with a standard deviation of 0.06. The study was carried out on 21 healthy subjects and 20 diabetes patients. The linear relationship (r = 0.91) between each subjects age and AGI was found, and a linear model with regression line was constructed. For diabetes patients, the mean AGI value difference from the proposed model y(AGI) was found to be 0.359. The difference was found between healthy and diabetes patients groups with significance level of P andlt; 0.0005.

Place, publisher, year, edition, pages
Hindawi Publishing Corporation , 2013. Vol. 2013
National Category
Engineering and Technology
URN: urn:nbn:se:liu:diva-97461DOI: 10.1155/2013/169035ISI: 000323341400001OAI: diva2:647768

Funding Agencies|Estonian Science Foundation|7506|Estonian Targeted Financing Project|SF0140027s07|European Union through the European Regional Development Fund||

Available from: 2013-09-12 Created: 2013-09-12 Last updated: 2014-10-30

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Lindberg, Lars-Göran
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