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Synthesis and characterization of superparamagnetic iron oxide nanoparticles coated with silica
KTH, School of Information and Communication Technology (ICT).
2012 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Multifunctional superparamagnetic iron oxide nanoparticles (SPIONs) coated with silica are a promising research field for lots of biomedical applications. The scope of this work is a preparation of SPIONs and coating them with silica to form core-shell structured nanoparticles for nanomedicine applications.

SPIONs were synthesized by two chemical methods – co-precipitation and thermal decomposition of organic iron precursor. Prepared nanoparticles were carefully characterized –average size, size distribution, morphology, crystallinity, colloidal stability and magnetic properties were studied. After comparing SPIONs synthetized by two routes the most suitable method for biomedical applicable nanoparticles preparation is determined. The nanomedicine requires nanoparticles of the highest quality.

The next step was coating SPIONs with silica shell. For this purpose inverse microemulsion method was chosen. TEOS was used as a silica precursor. Mean size, size distribution, magnetic properties, structure of silica shell were studied.

Place, publisher, year, edition, pages
2012. , 50 p.
TRITA-ICT-EX, 2012:314
Keyword [en]
magnetite, co-precipitation, thermal decomposition, silica, inverse microemulsion, TEOS, biomedical applications, core-shell
National Category
Engineering and Technology
URN: urn:nbn:se:kth:diva-121520OAI: diva2:618655
Subject / course
Microelectronics and Applied Physics
Available from: 2013-04-29 Created: 2013-04-29 Last updated: 2014-01-17Bibliographically approved

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