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Acetylene in breath: background levels and real-time elimination kinetics after smoking
University of Helsinki. (Laboratory of Physical Chemistry)ORCID iD: 0000-0002-5065-7786
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2010 (English)In: Journal of Breath Research, ISSN 1752-7155, E-ISSN 1752-7163, Vol. 4, no 4, 046003Article in journal (Refereed) Published
Abstract [en]

We have measured the acetylene concentration in the exhaled breath of 40 volunteers (31 non-smokers, nine smokers) using near-infrared cavity ring-down spectroscopy. The acetylene levels were found to be the same as in ambient air for non-smokers, whereas elevated levels were observed for smokers. Real-time measurements with sub-second time resolution have been applied to measure the elimination kinetics of acetylene in breath after exposure to tobacco smoke. Three exponential time constants can be distinguished from the data and these can be used to define the residence times for different compartments, according to the multi-compartment model of the human body.

Place, publisher, year, edition, pages
Bristol, UK: Institute of Physics Publishing (IOPP), 2010. Vol. 4, no 4, 046003
Keyword [en]
reaction-mass-spectrometry, exhaled breath, ethane traces, cavity ring, ptr-ms, spectroscopy, hydrocarbons, biomarkers, ethylene, region
National Category
Biophysics Medical Biotechnology Medical Engineering Atom and Molecular Physics and Optics
Identifiers
URN: urn:nbn:se:umu:diva-64490DOI: 10.1088/1752-7155/4/4/046003ISI: 000284756600004OAI: oai:DiVA.org:umu-64490DiVA: diva2:601744
Note

687DS Times Cited:2 Cited References Count:29

Available from: 2013-01-30 Created: 2013-01-30 Last updated: 2017-12-06Bibliographically approved

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Schmidt, Florian M.

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