Change search
ReferencesLink to record
Permanent link

Direct link
Legionnaires' disease from a cooling tower in a community outbreak in Lidkoping, Sweden-epidemiological, environmental and microbiological investigation supported by meteorological modelling
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Microbiology and Infectious Medicine.
Show others and affiliations
2012 (English)In: BMC Infectious Diseases, ISSN 1471-2334, Vol. 12, 313- p.Article in journal (Refereed) Published
Abstract [en]

Background: An outbreak of Legionnaires' Disease took place in the Swedish town Lidkoping on Lake Vanern in August 2004 and the number of pneumonia cases at the local hospital increased markedly. As soon as the first patients were diagnosed, health care providers were informed and an outbreak investigation was launched. Methods: Classical epidemiological investigation, diagnostic tests, environmental analyses, epidemiological typing and meteorological methods. Results: Thirty-two cases were found. The median age was 62 years (range 36 - 88) and 22 (69%) were males. No common indoor exposure was found. Legionella pneumophila serogroup 1 was found at two industries, each with two cooling towers. In one cooling tower exceptionally high concentrations, 1.2 x 10(9) cfu/L, were found. Smaller amounts were also found in the other tower of the first industry and in one tower of the second plant. Sero-and genotyping of isolated L. pneumophila serogroup 1 from three patients and epidemiologically suspected environmental strains supported the cooling tower with the high concentration as the source. In all, two L. pneumophila strains were isolated from three culture confirmed cases and both these strains were detected in the cooling tower, but one strain in another cooling tower as well. Meteorological modelling demonstrated probable spread from the most suspected cooling tower towards the town centre and the precise location of four cases that were stray visitors to Lidkoping. Conclusions: Classical epidemiological, environmental and microbiological investigation of an LD outbreak can be supported by meteorological modelling methods. The broad competence and cooperation capabilities in the investigation team from different authorities were of paramount importance in stopping this outbreak.

Place, publisher, year, edition, pages
2012. Vol. 12, 313- p.
Keyword [en]
Legionnaires' disease, Outbreak, Epidemiology, Cooling tower, Meteorological computer models, Sequence based typing
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-193039DOI: 10.1186/1471-2334-12-313ISI: 000312983300001OAI: diva2:601201
Available from: 2013-01-28 Created: 2013-01-28 Last updated: 2013-01-28Bibliographically approved

Open Access in DiVA

fulltext(1196 kB)42 downloads
File information
File name FULLTEXT01.pdfFile size 1196 kBChecksum SHA-512
Type fulltextMimetype application/pdf

Other links

Publisher's full text
By organisation
Clinical Microbiology and Infectious Medicine
In the same journal
BMC Infectious Diseases
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 42 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 228 hits
ReferencesLink to record
Permanent link

Direct link