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Important differences between topoisomerase-I and -II targeting agents
Manitoba Institute of Cell Biology, Winnipeg, Manitoba, Canada .
Manitoba Institute of Cell Biology, Cancer Care Manitoba; Manitoba Institute of Child Health; Department of Biochemistry and Medical Genetics; Department of Human Anatomy and Cell Science, University Manitoba, Winnipeg, Canada.ORCID iD: 0000-0001-9518-1411
2006 (English)In: Cancer Biology & Therapy, ISSN 1538-4047, E-ISSN 1555-8576, Vol. 5, no 8, 965-966 p.Article in journal, Letter (Other academic) Published
Abstract [en]

Commentary to: Activation of ATM and Histone H2AX Phosphorylation Induced by Mitoxantrone But Not by Topotecan is Prevented by the Antioxidant N-acetyl-L-Cysteine Xuan Huang, Akira Kurose, Toshiki Tanaka, Frank Traganos, Wei Dai and Zbigniew Darzynkiewicz

 

Place, publisher, year, edition, pages
Landes Bioscience , 2006. Vol. 5, no 8, 965-966 p.
Keyword [en]
Apoptosis, atm, camptothecin, dependent protein-kinase, dna-damage, double-strand breaks, histone h2ax, inhibitor, mitoxantrone, perspective, phosphorylation, reactive oxygen species (ROS), topoisomerase targeting agents, topotecan, x2hs
National Category
Biochemistry and Molecular Biology Genetics Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
Identifiers
URN: urn:nbn:se:liu:diva-86982DOI: 10.4161/cbt.5.8.3274ISI: 000242400700020OAI: oai:DiVA.org:liu-86982DiVA: diva2:584079
Note

 

 

Available from: 2013-01-08 Created: 2013-01-08 Last updated: 2017-12-06

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Los, Marek Jan
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