Development of iridium-catalyzed asymmetric hydrogenation: New catalysts, new substrate scope
2012 (English)In: Journal of Organometallic Chemistry, ISSN 0022-328X, E-ISSN 1872-8561, Vol. 714, 3-11 p.Article, review/survey (Refereed) Published
A review. The asym. hydrogenation of olefins is a tremendously powerful tool used to synthesize chiral mols. The field was pioneered using rhodium- and ruthenium- based catalysts; however, catalysts based on both of these metals suffer from limitations, such as the need for directing substituents near or even adjacent to the olefin. Iridium-based catalysts do not suffer from this flaw and can thus hydrogenate a wide variety of olefins, including some tetra substituted ones. It is also possible for iridium-based catalysts to hydrogenate hetero-π bonds such as those found in heteroarom. rings. This review summarizes the contributions made to this field by the authors in the past few years. [on SciFinder(R)]
Place, publisher, year, edition, pages
2012. Vol. 714, 3-11 p.
review iridium catalyst asym hydrogenation alkene heteroarom
Research subject Chemistry
IdentifiersURN: urn:nbn:se:uu:diva-187584DOI: 10.1016/j.jorganchem.2012.04.002ISI: 000306239400003OAI: oai:DiVA.org:uu-187584DiVA: diva2:575232