Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Shift work and cardiovascular disease
Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
2012 (English)Licentiate thesis, comprehensive summary (Other academic)
Abstract [en]

Shift work is a work schedule being the opposite of normal daytime work, often defined as working time outside normal daytime hours (06:00 to 18:00). In recent years, shift work has been associated with an increased risk of numerous chronic conditions including for example cardiovascular disease, some types of cancer, type II diabetes, and the metabolic syndrome. While some studies on the association between shift work and chronic disease have found results supporting it, others have not. Therefore, more research is needed to clarify potential associations.The aim of this thesis was to further study the proposed association between shift work and cardiovascular disease. This was addressed by performing two studies, one analysing if shift workers had an increased risk of ischemic stroke compared to day workers. The other study analysed whether shift workers had an increased risk of short-term mortality (case fatality) after a myocardial infarction compared to day workers. The studies were performed using logistic regression analysis in two different case-control databasesThe findings from the first study indicated that shift workers did not have an increased risk of ischemic stroke. The findings from the second study showed that male shift workers had an increased risk of death within 28 days after a myocardial infarction; the results did not indicate an increased risk for female shift workers. The results from both studies were adjusted for both behavioural and medical risk factors without affecting the results. The findings from this thesis provide new evidence showing that male shift workers have an increased risk of death 28 days after a myocardial infarction, however more research is needed to clarify and characterise any such potential associations.

Place, publisher, year, edition, pages
Sundsvall: Mid Sweden University , 2012. , 26 p.
Series
Mid Sweden University licentiate thesis, ISSN 1652-8948 ; 89
Keyword [en]
Shift work, epidemiology, cardiovascular disease, stroke, case fatality
National Category
Health Sciences
Identifiers
URN: urn:nbn:se:miun:diva-17466ISBN: 978-91-87103-32-2 (print)OAI: oai:DiVA.org:miun-17466DiVA: diva2:572531
Supervisors
Available from: 2012-11-28 Created: 2012-11-28 Last updated: 2012-11-30Bibliographically approved
List of papers
1. Ischemic stroke and shift work
Open this publication in new window or tab >>Ischemic stroke and shift work
Show others...
2007 (English)In: Scandinavian Journal of Work, Environment and Health, ISSN 0355-3140, E-ISSN 1795-990X, Vol. 33, no 6, 435-439 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: This study analyzed the potential association between shift work and ischemic stroke. METHODS: The analysis was carried out using a nested case-control study consisting of 138 shift workers and 469 day workers from the register of the Northern Sweden Monitoring of Trends and Determinants in Cardiovascular Diseases (MONICA) study and the Vasterbotten Intervention Programme. Logistic regression analysis was used to analyze the risk estimate for day workers in a comparison with shift workers and the risk of ischemic stroke. RESULTS: The crude odds ratio for shift workers' risk of experiencing an ischemic stroke was 1.0 (95% confidence interval 0.6-1.8) for both the men and the women. The risk estimates were consistent despite the introduction of several recognized risk factors for ischemic stroke in the logistic regression models. CONCLUSIONS: In the present study, none of the findings indicated a higher risk of shift workers undergoing an ischemic stroke than day workers.

Keyword
Ischemic stroke, shift work
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:miun:diva-4088 (URN)000253834000004 ()18327511 (PubMedID)2-s2.0-40749141220 (Scopus ID)4646 (Local ID)4646 (Archive number)4646 (OAI)
Available from: 2008-12-09 Created: 2008-12-09 Last updated: 2017-10-20Bibliographically approved
2. Case fatality of myocardial infarction among shift workers
Open this publication in new window or tab >>Case fatality of myocardial infarction among shift workers
Show others...
2015 (English)In: International Archives of Occupational and Environmental Health, ISSN 0340-0131, E-ISSN 1432-1246, Vol. 88, no 5, 599-605 p.Article in journal (Refereed) Published
Abstract [en]

Purpose: Shift work has been associated with an excess risk of cardiovascular disease (CVD) and more specifically myocardial infarction (MI). The majority of the studies that found a positive association between shift work and CVD have been based on incidence data. The results from studies on cardiovascular-related mortality among shift workers have shown little or no elevated mortality associated with shift work. None of the previous studies have analysed short-term mortality (case fatality) after MI. Therefore, we investigated whether shift work is associated with increased case fatality after MI compared with day workers.Methods: Data on incident cases with first MI were obtained from case–control study conducted in two geographical sites in Sweden (Stockholm Heart Epidemiology Program and Västernorrland Heart Epidemiology Program), including 1,542 cases (1,147 men and 395 women) of MI with complete working time information and 65 years or younger. Case fatality was defined as death within 28 days of onset of MI. Risk estimates were calculated using logistic regression.Results: The crude odds ratios for case fatality among male shift workers were 1.63 [95 % confidence interval (CI) 1.12, 2.38] and 0.56 (95 % CI 0.26, 1.18) for female shift workers compared with day workers. Adjustments for established cardiovascular risk factors such as diabetes type II and socio-economic status did not alter the results.Conclusion: Shift work was associated with increased risk of case fatality among male shift workers after the first MI.

Keyword
Cardiovascular disease, Case–control, Epidemiology, Risk estimation, Shift work
National Category
Health Sciences
Identifiers
urn:nbn:se:miun:diva-17465 (URN)10.1007/s00420-014-0984-z (DOI)000354624400007 ()2-s2.0-84939876826 (Scopus ID)
Available from: 2012-11-28 Created: 2012-11-28 Last updated: 2017-12-07Bibliographically approved

Open Access in DiVA

Lic thesis 89(841 kB)859 downloads
File information
File name FULLTEXT01.pdfFile size 841 kBChecksum SHA-512
34687bec95e92c50737dd8b00eb9ceef352517d20a0f6f9e1624541eaec39dc44cb5fe43052cdb06b000e686f76dcf5720e1284ce80e1a17eec646c2cde70cd3
Type fulltextMimetype application/pdf

Search in DiVA

By author/editor
Hermansson, Jonas
By organisation
Department of Health Sciences
Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 859 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

isbn
urn-nbn

Altmetric score

isbn
urn-nbn
Total: 1236 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf