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Gender differences in psychological morbidity and treatment in intensive care survivors - a cohort study
Department of Anesthesiology, Surgical Services and Intensive Care Medicine, Karolinska University Hospital Solna, Sweden.
The Unit of Biostatistics, The Institution of Environmental Medicine, Karolinska Institute, Solna, Sweden.
Mid Sweden University, Faculty of Human Sciences, Department of Social Sciences.ORCID iD: 0000-0002-4116-5501
Department of Anesthesiology, Surgical Services and Intensive Care Medicine, Karolinska University Hospital Solna, Sweden.
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2012 (English)In: Critical Care, ISSN 1364-8535, E-ISSN 1466-609X, ISSN 1364-8535, Vol. 16, no 3, Art. no. R80- p.Article in journal (Refereed) Published
Abstract [en]


Many hospitals have initiated follow-up to facilitate rehabilitation after critical illness and intensive care, although the efficacy of such an intervention is uncertain. Studies in trauma research indicate significant differences in psychological reactions to traumatic events between men and women. Our aim was, in a quasi-experimental design, to compare psychological morbidity and treatment effects between men and women enrolled in a multidisciplinary intensive care unit (ICU) follow-up programme (follow-up group) and ICU patients not offered such follow-up (control group).


Men and women treated > 4 days in the ICU in 2006, before ICU follow-up started, were compared with men and women treated in 2007 and 2008, when all patients with ICU stay > 4 days were offered ICU follow-up at 3, 6 and 12 months post-ICU. Fourteen months after ICU discharge, psychological problems were measured with Impact of Event Scale (IES) for posttraumatic stress and Hospital Anxiety and Depression Scale (HADS) for anxiety and depression.


Women with no follow-up reported significantly higher IES scores than men. Women in the follow-up group reported significantly lower IES scores compared to women in the control group, both in crude analysis and after adjusting for significant confounders/predictors (age, ICU length of stay and previous psychological problems). Furthermore, the 75th percentile for IES and HADS-Depression scores (high scores and degree of symptoms of psychological problems) in women in the follow-up group was lower than in those without follow-up (IES: -17.4 p, p<.01, HADS-depression: -4.9 p, p<.05). For men, no significant differences were found between the no follow-up and the follow-up group.


Psychological problems after critical illness and intensive care appear to be more common in women than in men. A multidisciplinary ICU follow-up may reduce the incidence of long-term symptoms of posttraumatic stress and depression for women.

Place, publisher, year, edition, pages
2012. Vol. 16, no 3, Art. no. R80- p.
Keyword [en]
anxiety; critical care; critical illness; depression; follow-up; multidisciplinary; post-traumatic stress
National Category
URN: urn:nbn:se:miun:diva-17461DOI: 10.1186/cc11338ISI: 000313197500010ScopusID: 2-s2.0-84860797010OAI: diva2:572508
Available from: 2013-04-04 Created: 2012-11-28 Last updated: 2016-10-17Bibliographically approved

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Sundin, Örjan
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