Selective detection of bacterial layers with terahertz plasmonic antennas
2012 (English)In: Biomedical Optics Express, ISSN 2156-7085, Vol. 3, no 11, 2937-2949 p.Article in journal (Refereed) Published
Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate complex, time-consuming procedures. In a medical context, the determination of the bacteria Gram type is of significant interest. The diagnostic of microbial infection often requires the identification of the microbiological agent responsible for the infection, or at least the identification of its family (Gram type), in a matter of minutes. In this work, we propose to use terahertz frequency range antennas for the enhanced selective detection of bacteria types. Several microorganisms are investigated by terahertz time-domain spectroscopy: a fast, contactless and damage-free investigation method to gain information on the presence and the nature of the microorganisms. We demonstrate that plasmonic antennas enhance the detection sensitivity for bacterial layers and allow the selective recognition of the Gram type of the bacteria.
Place, publisher, year, edition, pages
2012. Vol. 3, no 11, 2937-2949 p.
Chemical Sciences Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-184698DOI: 10.1364/BOE.3.002937ISI: 000310644700023OAI: oai:DiVA.org:uu-184698DiVA: diva2:567429
FunderEU, FP7, Seventh Framework Programme, 224189Swedish Research Council, 621-2008-3562Swedish Research Council, 621-2011-4423