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Selective detection of bacterial layers with terahertz plasmonic antennas
Universität Stuttgart, Physikalisches Institut, Germany.
FOM Institute AMOLF, Centre for Nanophotonics, c/o Philips Research Laboratories, Eindhoven, Netherlands.
CEA Leti, MINATEC Campus, Department of microtechnologies for Biology and Healthcare, France.
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - BMC, Analytical Chemistry.
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2012 (English)In: Biomedical Optics Express, ISSN 2156-7085, Vol. 3, no 11, 2937-2949 p.Article in journal (Refereed) Published
Abstract [en]

Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate complex, time-consuming procedures. In a medical context, the determination of the bacteria Gram type is of significant interest. The diagnostic of microbial infection often requires the identification of the microbiological agent responsible for the infection, or at least the identification of its family (Gram type), in a matter of minutes. In this work, we propose to use terahertz frequency range antennas for the enhanced selective detection of bacteria types. Several microorganisms are investigated by terahertz time-domain spectroscopy: a fast, contactless and damage-free investigation method to gain information on the presence and the nature of the microorganisms. We demonstrate that plasmonic antennas enhance the detection sensitivity for bacterial layers and allow the selective recognition of the Gram type of the bacteria.

Place, publisher, year, edition, pages
2012. Vol. 3, no 11, 2937-2949 p.
National Category
Chemical Sciences Medical and Health Sciences
URN: urn:nbn:se:uu:diva-184698DOI: 10.1364/BOE.3.002937ISI: 000310644700023OAI: diva2:567429
EU, FP7, Seventh Framework Programme, 224189Swedish Research Council, 621-2008-3562Swedish Research Council, 621-2011-4423
Available from: 2012-11-15 Created: 2012-11-13 Last updated: 2012-12-10Bibliographically approved

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